Click here to switch to the map view.

The map label for this gene is tldD [H]

Identifier: 91781873

GI number: 91781873

Start: 547907

End: 549373

Strand: Reverse

Name: tldD [H]

Synonym: Bxe_A3972

Alternate gene names: 91781873

Gene position: 549373-547907 (Counterclockwise)

Preceding gene: 91781874

Following gene: 91781872

Centisome position: 11.22

GC content: 65.71

Gene sequence:

>1467_bases
ATGAACATCATCGAACCCGGTATCCGTAATCTCGCCACCGCCAAGGACATCCTCCTGACGCCCTATGGTCTCGACGAAGC
CCTGCTCACCCGCACGCTCGCCGAAATCTTCACGCACAAGATCGACTACGCCGACCTGTATTTCCAGTACACGCGCAGCG
AAGCGTGGAGTCTCGAAGAAGGCATCGTGAAGTCCGGCAGCTTCAGCATCGACCAGGGCGTCGGCGTGCGCGCCGTGTCG
GGCGACCGCACGGCGTTCGCCTATTCGGACGACCTGTCGCCCGAAGCGATCCGCCAGGCGGCGCTCGCCACCCGTTCGAT
CGCCAGGGCGGGCGGCGGCAAGCAGAAGATCAAGGTGGCCTCGTCGCTGACCGGCATTGCCGGGCGCGATCTGTATCTGC
CGGCCGATCCGCTGCATTCGCTCGACGCGACCGCCAAGGTCAAGCTGCTCGAGCGCATCGAAAAGATGGCGCGCGGCCGC
GATCCGCGCATCCAGCAGGTCATGGCGGGTCTCGCCGGCGAATACGACGTAGTGCTGGTCGCGCGCAGCGACGGCGGCTT
CGCGGCCGACATCCGGCCGCTCGTGCGCGTGTCGGTCACGGTGATCGCCGAGCAGAACGGCCGCCGCGAAATCGGCAGCG
GCGGCGGCGGCGGCCGCTTCGACTACGCCTATTTCACCGACGAGGTGCTGTCAGGCTATGTCGACGACGCGGTGCATGCG
GCGCTGGTGAACCTCGAAGCCCGTCCGGCGCCGGCCGGCGCGATGACCGTCGTGCTCGGACCGGGCTGGCCCGGCGTACT
GCTGCACGAAGCGATCGGCCACGGTCTGGAAGGCGACTTCAACCGCAAGGGTTCGTCGGCATTCGCGGGGCGCATCGGCG
AACAGGTGGCCGCCAGGGGCGTGACCGTGGTGGACGACGGCACGCTGCCGAACCGCCGCGGCTCGCTCAATATCGACGAC
GAAGGCAATCCGACCCAGTGCACCACGCTGATCGAAGACGGCATCCTGAAGGGCTACATCCAGGACACGCTGAACGCGCG
TCTGATGAAGATGCCGGTCACGGGCAATGCGCGCCGTGAGTCGTACGCCGCGCTACCCATGCCGCGCATGACCAACACGT
ACATGCTCAATGGCGACAAGGATCCGCAGGAAATCATCGCCTCCGTGAAGAACGGCTTGTATGCGGTGAACTTCGGCGGC
GGCCAGGTCGACATCACCAACGGCAAGTTCGTGTTCTCGGCTTCCGAGGCGTACATGATCGAAGACGGCAAGGTCACGTA
TCCGGTGAAGGGCGCAACGCTGATCGGCAGTGGTCCGGAATCGCTCAAATACGTCAGCATGATCGGCAACGACATGAAGC
TCGATTCGGGCGTGGGCGTGTGCGGCAAGGAAGGCCAGAGCGTGCCGGTGGGCGTCGGCCAGCCCACGCTGCGGATCGAC
CGGATGACGGTTGGCGGCACTGCCTGA

Upstream 100 bases:

>100_bases
CAACCCACTCGTGTGACATTGAAAGTGCGGCGCCCTGGACTCATTTGTGAGTGACAGACGCGCTAACCGAATCCTTCGTA
TCGAGCAGAACATACTTCGC

Downstream 100 bases:

>100_bases
TTCGTTACAAACGCATACTTCGTGCATACATTGCGCGAAGTATGCGGATTTCCCGCATTTTTATGCCCGGTAGCTTGCAA
GTGCAGCCTGACCGGGTTAT

Product: microcin-processing peptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MNIIEPGIRNLATAKDILLTPYGLDEALLTRTLAEIFTHKIDYADLYFQYTRSEAWSLEEGIVKSGSFSIDQGVGVRAVS
GDRTAFAYSDDLSPEAIRQAALATRSIARAGGGKQKIKVASSLTGIAGRDLYLPADPLHSLDATAKVKLLERIEKMARGR
DPRIQQVMAGLAGEYDVVLVARSDGGFAADIRPLVRVSVTVIAEQNGRREIGSGGGGGRFDYAYFTDEVLSGYVDDAVHA
ALVNLEARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAARGVTVVDDGTLPNRRGSLNIDD
EGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDKDPQEIIASVKNGLYAVNFGG
GQVDITNGKFVFSASEAYMIEDGKVTYPVKGATLIGSGPESLKYVSMIGNDMKLDSGVGVCGKEGQSVPVGVGQPTLRID
RMTVGGTA

Sequences:

>Translated_488_residues
MNIIEPGIRNLATAKDILLTPYGLDEALLTRTLAEIFTHKIDYADLYFQYTRSEAWSLEEGIVKSGSFSIDQGVGVRAVS
GDRTAFAYSDDLSPEAIRQAALATRSIARAGGGKQKIKVASSLTGIAGRDLYLPADPLHSLDATAKVKLLERIEKMARGR
DPRIQQVMAGLAGEYDVVLVARSDGGFAADIRPLVRVSVTVIAEQNGRREIGSGGGGGRFDYAYFTDEVLSGYVDDAVHA
ALVNLEARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAARGVTVVDDGTLPNRRGSLNIDD
EGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDKDPQEIIASVKNGLYAVNFGG
GQVDITNGKFVFSASEAYMIEDGKVTYPVKGATLIGSGPESLKYVSMIGNDMKLDSGVGVCGKEGQSVPVGVGQPTLRID
RMTVGGTA
>Mature_488_residues
MNIIEPGIRNLATAKDILLTPYGLDEALLTRTLAEIFTHKIDYADLYFQYTRSEAWSLEEGIVKSGSFSIDQGVGVRAVS
GDRTAFAYSDDLSPEAIRQAALATRSIARAGGGKQKIKVASSLTGIAGRDLYLPADPLHSLDATAKVKLLERIEKMARGR
DPRIQQVMAGLAGEYDVVLVARSDGGFAADIRPLVRVSVTVIAEQNGRREIGSGGGGGRFDYAYFTDEVLSGYVDDAVHA
ALVNLEARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAARGVTVVDDGTLPNRRGSLNIDD
EGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDKDPQEIIASVKNGLYAVNFGG
GQVDITNGKFVFSASEAYMIEDGKVTYPVKGATLIGSGPESLKYVSMIGNDMKLDSGVGVCGKEGQSVPVGVGQPTLRID
RMTVGGTA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=485, Percent_Identity=58.7628865979381, Blast_Score=547, Evalue=1e-157,
Organism=Escherichia coli, GI1790682, Length=452, Percent_Identity=24.3362831858407, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51822; Mature: 51822

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIEPGIRNLATAKDILLTPYGLDEALLTRTLAEIFTHKIDYADLYFQYTRSEAWSLEE
CCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCHHH
GIVKSGSFSIDQGVGVRAVSGDRTAFAYSDDLSPEAIRQAALATRSIARAGGGKQKIKVA
HHHCCCCCEECCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
SSLTGIAGRDLYLPADPLHSLDATAKVKLLERIEKMARGRDPRIQQVMAGLAGEYDVVLV
HHHCCCCCCEEECCCCCCHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEE
ARSDGGFAADIRPLVRVSVTVIAEQNGRREIGSGGGGGRFDYAYFTDEVLSGYVDDAVHA
EECCCCCCHHCCCEEEEEEEEEECCCCCEECCCCCCCCCEEHHEEHHHHHHHHHHHHHHH
ALVNLEARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAARG
HHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCC
VTVVDDGTLPNRRGSLNIDDEGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRE
CEEEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
SYAALPMPRMTNTYMLNGDKDPQEIIASVKNGLYAVNFGGGQVDITNGKFVFSASEAYMI
CEECCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEE
EDGKVTYPVKGATLIGSGPESLKYVSMIGNDMKLDSGVGVCGKEGQSVPVGVGQPTLRID
ECCEEEEEECCCEEECCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEE
RMTVGGTA
EEECCCCC
>Mature Secondary Structure
MNIIEPGIRNLATAKDILLTPYGLDEALLTRTLAEIFTHKIDYADLYFQYTRSEAWSLEE
CCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCHHH
GIVKSGSFSIDQGVGVRAVSGDRTAFAYSDDLSPEAIRQAALATRSIARAGGGKQKIKVA
HHHCCCCCEECCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
SSLTGIAGRDLYLPADPLHSLDATAKVKLLERIEKMARGRDPRIQQVMAGLAGEYDVVLV
HHHCCCCCCEEECCCCCCHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEE
ARSDGGFAADIRPLVRVSVTVIAEQNGRREIGSGGGGGRFDYAYFTDEVLSGYVDDAVHA
EECCCCCCHHCCCEEEEEEEEEECCCCCEECCCCCCCCCEEHHEEHHHHHHHHHHHHHHH
ALVNLEARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAARG
HHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCC
VTVVDDGTLPNRRGSLNIDDEGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRE
CEEEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
SYAALPMPRMTNTYMLNGDKDPQEIIASVKNGLYAVNFGGGQVDITNGKFVFSASEAYMI
CEECCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEE
EDGKVTYPVKGATLIGSGPESLKYVSMIGNDMKLDSGVGVCGKEGQSVPVGVGQPTLRID
ECCEEEEEECCCEEECCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEE
RMTVGGTA
EEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]