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The map label for this gene is gmhB [H]

Identifier: 91781831

GI number: 91781831

Start: 500410

End: 500964

Strand: Reverse

Name: gmhB [H]

Synonym: Bxe_A4014

Alternate gene names: 91781831

Gene position: 500964-500410 (Counterclockwise)

Preceding gene: 91781832

Following gene: 91781830

Centisome position: 10.23

GC content: 66.31

Gene sequence:

>555_bases
ATGCCGACCAAAAAAGTGGTGATCCTCGACCGCGACGGCGTGATCAACGTCGACTCCGACGCGTTCATCAAGTCGCCGGA
CGAATGGGTCGCCCTGCCCGGTGCGCTGGAAGCCATCGCGCGTCTGAACCAGGCGGGCTACCGCGTGGCGATCGCGACCA
ACCAGTCGGGCATCGGCCGCGGCCTGTTCGACATGAACGCGCTCAATGCAATGCACCTGAAGATGCATCGCATGGCGGCC
GCCGTCGGCGGGCGCATCGACGCGGTGTTCTTCTGCCCGCACACGGCGGAGGACCACTGCGAATGCCGCAAGCCGAAGCC
CGGCATGCTGAAGATGATCACGGAGCGCTTCGAGGTCGATCCGGAAAATACGCCGGTAGTGGGCGACGCCATGCGCGATC
TGCAAGCCGGCGCGGCGCTCGGCCATCCGGTTCACCTGGTGCTGACGGGCAAGGGCCGCAAAACGCTCGCGGCCGGCGGC
TTGCCCGAAGGCACGATCGTGCACGACGACCTGCGTGCGTTCGCGCTCGACTTCCTCGCCGACGCTCAAGAGTGA

Upstream 100 bases:

>100_bases
CCCGCGTTGCGCGCCAACCGTCTGGCCTTGCTCGGCGCACTGCATCAGCAGATGAACTGCGTCGCCGACATTTCCCGACT
CGCCGCCTGAGCCCCGCGCC

Downstream 100 bases:

>100_bases
CGCGCGCCACGCGCGTCCCCATTCCTCACTGACCACGCCGATGCGCTTCATCCGTTCTTTGCTTCTGCTGATCTACTTCG
TTCTGTTCACGGTGCCGTAC

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MPTKKVVILDRDGVINVDSDAFIKSPDEWVALPGALEAIARLNQAGYRVAIATNQSGIGRGLFDMNALNAMHLKMHRMAA
AVGGRIDAVFFCPHTAEDHCECRKPKPGMLKMITERFEVDPENTPVVGDAMRDLQAGAALGHPVHLVLTGKGRKTLAAGG
LPEGTIVHDDLRAFALDFLADAQE

Sequences:

>Translated_184_residues
MPTKKVVILDRDGVINVDSDAFIKSPDEWVALPGALEAIARLNQAGYRVAIATNQSGIGRGLFDMNALNAMHLKMHRMAA
AVGGRIDAVFFCPHTAEDHCECRKPKPGMLKMITERFEVDPENTPVVGDAMRDLQAGAALGHPVHLVLTGKGRKTLAAGG
LPEGTIVHDDLRAFALDFLADAQE
>Mature_183_residues
PTKKVVILDRDGVINVDSDAFIKSPDEWVALPGALEAIARLNQAGYRVAIATNQSGIGRGLFDMNALNAMHLKMHRMAAA
VGGRIDAVFFCPHTAEDHCECRKPKPGMLKMITERFEVDPENTPVVGDAMRDLQAGAALGHPVHLVLTGKGRKTLAAGGL
PEGTIVHDDLRAFALDFLADAQE

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=154, Percent_Identity=35.0649350649351, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI87082027, Length=141, Percent_Identity=30.4964539007092, Blast_Score=85, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 19792; Mature: 19661

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTKKVVILDRDGVINVDSDAFIKSPDEWVALPGALEAIARLNQAGYRVAIATNQSGIGR
CCCCEEEEEECCCEEEECCCCEEECCCCEEECCHHHHHHHHHCCCCEEEEEEECCCCCCC
GLFDMNALNAMHLKMHRMAAAVGGRIDAVFFCPHTAEDHCECRKPKPGMLKMITERFEVD
CCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCCCCCHHHHHHHHHCCC
PENTPVVGDAMRDLQAGAALGHPVHLVLTGKGRKTLAAGGLPEGTIVHDDLRAFALDFLA
CCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCCCCCCCEEHHHHHHHHHHHHH
DAQE
CCCC
>Mature Secondary Structure 
PTKKVVILDRDGVINVDSDAFIKSPDEWVALPGALEAIARLNQAGYRVAIATNQSGIGR
CCCEEEEEECCCEEEECCCCEEECCCCEEECCHHHHHHHHHCCCCEEEEEEECCCCCCC
GLFDMNALNAMHLKMHRMAAAVGGRIDAVFFCPHTAEDHCECRKPKPGMLKMITERFEVD
CCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCCCCCHHHHHHHHHCCC
PENTPVVGDAMRDLQAGAALGHPVHLVLTGKGRKTLAAGGLPEGTIVHDDLRAFALDFLA
CCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCCCCCCCEEHHHHHHHHHHHHH
DAQE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919; 12101286 [H]