Click here to switch to the map view.

The map label for this gene is pdxA [H]

Identifier: 91781823

GI number: 91781823

Start: 493118

End: 494128

Strand: Direct

Name: pdxA [H]

Synonym: Bxe_A4022

Alternate gene names: 91781823

Gene position: 493118-494128 (Clockwise)

Preceding gene: 91781822

Following gene: 91781824

Centisome position: 10.07

GC content: 69.24

Gene sequence:

>1011_bases
ATGACAACCGCCGCCCAGTCCGTCCGCCCACCGTTGCAGATCGCGATCACGACCGGCGAGCCCGCCGGCGTCGGCCCCGA
GCTGACGGCGCAGGCGCTCGCCGGCGCGGCGGCGCATTGGCCCCACGCGCAGTTCATCGTGCTGGGCGACGCGGACCTGC
TGGCCGAACGCGCGCGCGCCGTGGGTGTCGATTGGCGCGCGCTGGTGGCGGACGGCAAGCGCGTGCGCCTGCAACACCGG
CCGCTTGCGGCGCCTGCGGTCGCGGGCAAGCTGAACGCGGCCAACGGCCGCTACGTGCTCGATCTGCTCGACAGCGCAAT
CGACGCAGCGGTGGCCGGCACCTTCGACGCGATCGTGACCGCGCCGCTGCAAAAGAGCACCATCAACGACGCCGGCGTGC
CGTTCACCGGCCACACCGAATATCTGGCCGAGCGCACGCATACGCCGCGCGTGGTGATGATGCTGGCCGGCACCGGCAAG
CGGCCGTTGCGGGTCGCGCTGGCAACCACGCATCTGCCGCTCAAGGATGTTTCCGCCGCGCTGTCGATCGAAGGCATTCT
CGAAACGCTTCGCATCATCGATCACGATTTGCGGCATCACTTCGGCTTGCCGGCGCCGCGTATTCTCGTGACCGGGCTGA
ACCCGCACGCGGGCGAAAACGGTTATCTTGGCCGCGAGGAAATCGAGGTCATCACGCCGGCGCTAAAGCTCGCGGACGCT
CAAGGCATCGACGCGCGCGGCCCGTACCCGGCCGACACGCTGTTCCAGCCGCGTTACCTGGAGCAGGCCGACTGCGTGCT
GGCCATGTTCCACGACCAGGGTCTGCCGGTGTTGAAGTACGCCACGTTCGGCGAAGGCATCAATGTCACGCTCGGCTTGC
CGATCATCCGCACTTCGGTCGATCACGGCACCGCGCTCGACCTGGCGGGCACGGGCCGCGCCGACGCGGGCAGCCTGATC
GCTGCGATCGATACGGCGGTGTCGATGGCGCAGCATCGCCGCGCGGGCTGA

Upstream 100 bases:

>100_bases
AGCGCAAGGCGGAACAGGCCTACGCCGACTGGTTGCGCGAACTGCGCGACACCGCGTATGTCGAAGTGAAGCCCACGCTG
TCGAGCACGCAATAACCGTC

Downstream 100 bases:

>100_bases
TTCGGCGCCGCGGCGCCTTGCACGTTCGTTGCGCGTTCGTTGCGCGTTTTATACGCTGCCGCGGGCAGCAGGTGCGGCAC
GGCGCGCCCGCGCAACCAAG

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTTAAQSVRPPLQIAITTGEPAGVGPELTAQALAGAAAHWPHAQFIVLGDADLLAERARAVGVDWRALVADGKRVRLQHR
PLAAPAVAGKLNAANGRYVLDLLDSAIDAAVAGTFDAIVTAPLQKSTINDAGVPFTGHTEYLAERTHTPRVVMMLAGTGK
RPLRVALATTHLPLKDVSAALSIEGILETLRIIDHDLRHHFGLPAPRILVTGLNPHAGENGYLGREEIEVITPALKLADA
QGIDARGPYPADTLFQPRYLEQADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALDLAGTGRADAGSLI
AAIDTAVSMAQHRRAG

Sequences:

>Translated_336_residues
MTTAAQSVRPPLQIAITTGEPAGVGPELTAQALAGAAAHWPHAQFIVLGDADLLAERARAVGVDWRALVADGKRVRLQHR
PLAAPAVAGKLNAANGRYVLDLLDSAIDAAVAGTFDAIVTAPLQKSTINDAGVPFTGHTEYLAERTHTPRVVMMLAGTGK
RPLRVALATTHLPLKDVSAALSIEGILETLRIIDHDLRHHFGLPAPRILVTGLNPHAGENGYLGREEIEVITPALKLADA
QGIDARGPYPADTLFQPRYLEQADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALDLAGTGRADAGSLI
AAIDTAVSMAQHRRAG
>Mature_335_residues
TTAAQSVRPPLQIAITTGEPAGVGPELTAQALAGAAAHWPHAQFIVLGDADLLAERARAVGVDWRALVADGKRVRLQHRP
LAAPAVAGKLNAANGRYVLDLLDSAIDAAVAGTFDAIVTAPLQKSTINDAGVPFTGHTEYLAERTHTPRVVMMLAGTGKR
PLRVALATTHLPLKDVSAALSIEGILETLRIIDHDLRHHFGLPAPRILVTGLNPHAGENGYLGREEIEVITPALKLADAQ
GIDARGPYPADTLFQPRYLEQADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALDLAGTGRADAGSLIA
AIDTAVSMAQHRRAG

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=326, Percent_Identity=51.840490797546, Blast_Score=321, Evalue=4e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 35363; Mature: 35232

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAAQSVRPPLQIAITTGEPAGVGPELTAQALAGAAAHWPHAQFIVLGDADLLAERARA
CCCCCHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHH
VGVDWRALVADGKRVRLQHRPLAAPAVAGKLNAANGRYVLDLLDSAIDAAVAGTFDAIVT
CCCCCEEEECCCCEEEEECCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHEE
APLQKSTINDAGVPFTGHTEYLAERTHTPRVVMMLAGTGKRPLRVALATTHLPLKDVSAA
CCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHH
LSIEGILETLRIIDHDLRHHFGLPAPRILVTGLNPHAGENGYLGREEIEVITPALKLADA
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCC
QGIDARGPYPADTLFQPRYLEQADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSV
CCCCCCCCCCCCCCCCCCHHCCCCEEEEEECCCCCCEEEEEECCCCEEEEECCEEEEECC
DHGTALDLAGTGRADAGSLIAAIDTAVSMAQHRRAG
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTAAQSVRPPLQIAITTGEPAGVGPELTAQALAGAAAHWPHAQFIVLGDADLLAERARA
CCCCHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHH
VGVDWRALVADGKRVRLQHRPLAAPAVAGKLNAANGRYVLDLLDSAIDAAVAGTFDAIVT
CCCCCEEEECCCCEEEEECCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHEE
APLQKSTINDAGVPFTGHTEYLAERTHTPRVVMMLAGTGKRPLRVALATTHLPLKDVSAA
CCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHH
LSIEGILETLRIIDHDLRHHFGLPAPRILVTGLNPHAGENGYLGREEIEVITPALKLADA
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCC
QGIDARGPYPADTLFQPRYLEQADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSV
CCCCCCCCCCCCCCCCCCHHCCCCEEEEEECCCCCCEEEEEECCCCEEEEECCEEEEECC
DHGTALDLAGTGRADAGSLIAAIDTAVSMAQHRRAG
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA