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The map label for this gene is yyaJ [H]

Identifier: 91781755

GI number: 91781755

Start: 410217

End: 411632

Strand: Reverse

Name: yyaJ [H]

Synonym: Bxe_A4090

Alternate gene names: 91781755

Gene position: 411632-410217 (Counterclockwise)

Preceding gene: 91781764

Following gene: 91781754

Centisome position: 8.41

GC content: 63.77

Gene sequence:

>1416_bases
ATGTACATGGAAAAGGAGATTGCCGGCACGGCCGGCGTGCAAGCAAGCGTTTCGGCGCGGCTCGACCGCCTGCCCCCGAC
GCGCTATTTCAGCGGCCTCGTCGCACGCATCGCGATCGGCGGCTGGTTCGAGTTTTATGAAATGTTCATGGCGGCCTATA
TCTCACTGGGACTCATCAGCAGCGGCCTGTATCGCGCCACCACGGCCGGCCTGTTCGACGTCGACGGCTTCGCCAGCTTT
CTCGGCTCGTTTTTCGCCGGAATGTTCGTGGGCACGGTGGCGCTCGGCGGCTTCACCGACCGCTTCGGACGCCGCGCCGT
ATTCACCTGCGCAATGCTGATCTATTCGGTCGCGACCTTCGCCGCGGCGTTCCAGCATTCGCCGCAAGCGATGGATCTCT
GGCGCTTCGTCGCGGGCCTCGGCATCGGCGTGCAGCTCATTACTGTCGACACTTATATTTCCGAGCTCACGCCGCATCAC
ACCCGCGGCCGCTACAGCGCGTTCAGCATCCTCGTGATCCTGACTTCCGTGCCGACCGTCGCCGTACTGTCGTTTCTGCT
CGTGCCGCACACCATCCTAGGTCTCGAGGGTTGGCGCTGGGTGATGATCATCGGCTCGGCGGGCGCCGTGCTGATCTGGT
TCATGCGGCGCGGCCTTCCGGAGTCGCCGCGCTGGCTCGAAAGCAAAGGCCGGCTCGACGAAGCGCGCGCGATCGTCGAC
GCGATCGAGGCTCGCGTGGTCGCGGAAACCGGCCGCGCATTGCAGGCGCCGGCACAGCGCGCGCCGCAACCGTTGACCGG
CGAGCACGGCGGTTCCTGGTCGGAGATGTGGAAAGGCCGCTATCTGAGCCGCACCATCATGCTGTCGTTCTTCAACTTCT
TCCAGACCTTCGGCGTGTACGGCTTCGGCGCGTGGGTGCCGGTGCTGCTGTACACGAAAGGCATCACGATCACGCATTCG
CTGCTCTACACGATGGTGATCGCGTTCGCGACGCCGCTAGGCGCGCTCGGTGCGATGGCGTGTGCGGAGCGCATCCAGCG
CAAGTGGCAACTGGTCGGCTGCGCGATCGTCGTGGCGGTGGCCGGCGTACTGTTCGGCATGGTGCGCGAGCCGTTGCTGA
TCCTGCTGTTCGGCAGCGCCGTGACCATCGCGAACAACTGGCTGATCGGTATCTTTCACACCTATCAGGCCGAGCTGTAT
CCGACCCGGATTCGCGCCCGCGCCGTCGGTTTCGTGTTTAGCTGGAGCCGTCTGAGTTCGATCTTCGTCGGTTTCTGGGT
GGCGGCATTGCTCAAGCATTCGGGCGTGCCCGCCGTGTTCGTGCTGATTTCGTCAGCCATGTTCGTGATCGTCGTGATGG
TCGGGCTGCTAGGGCCGAAGACCAACGGCATTCGTCTGGAGGAGTTGTCTCAATGA

Upstream 100 bases:

>100_bases
GTTAATAGAATTTCACTTGAAATATGCCGATGATTCGTCCTACACTTGCCAAAAGTGTCGACACTATCAATATAGGACAT
CAGTCCAGCCAGGAGACGGC

Downstream 100 bases:

>100_bases
GTTCCATCGCCGCCGCATTCGCGCACGGCCTTTTCGCACTGGCGCAGCGTCCGCTGCCGGTTCCGGTCGCAGAGGAAGCC
AGGCGTTCGCTGATCAATGT

Product: major facilitator superfamily metabolite(sugar)/H(+) symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MYMEKEIAGTAGVQASVSARLDRLPPTRYFSGLVARIAIGGWFEFYEMFMAAYISLGLISSGLYRATTAGLFDVDGFASF
LGSFFAGMFVGTVALGGFTDRFGRRAVFTCAMLIYSVATFAAAFQHSPQAMDLWRFVAGLGIGVQLITVDTYISELTPHH
TRGRYSAFSILVILTSVPTVAVLSFLLVPHTILGLEGWRWVMIIGSAGAVLIWFMRRGLPESPRWLESKGRLDEARAIVD
AIEARVVAETGRALQAPAQRAPQPLTGEHGGSWSEMWKGRYLSRTIMLSFFNFFQTFGVYGFGAWVPVLLYTKGITITHS
LLYTMVIAFATPLGALGAMACAERIQRKWQLVGCAIVVAVAGVLFGMVREPLLILLFGSAVTIANNWLIGIFHTYQAELY
PTRIRARAVGFVFSWSRLSSIFVGFWVAALLKHSGVPAVFVLISSAMFVIVVMVGLLGPKTNGIRLEELSQ

Sequences:

>Translated_471_residues
MYMEKEIAGTAGVQASVSARLDRLPPTRYFSGLVARIAIGGWFEFYEMFMAAYISLGLISSGLYRATTAGLFDVDGFASF
LGSFFAGMFVGTVALGGFTDRFGRRAVFTCAMLIYSVATFAAAFQHSPQAMDLWRFVAGLGIGVQLITVDTYISELTPHH
TRGRYSAFSILVILTSVPTVAVLSFLLVPHTILGLEGWRWVMIIGSAGAVLIWFMRRGLPESPRWLESKGRLDEARAIVD
AIEARVVAETGRALQAPAQRAPQPLTGEHGGSWSEMWKGRYLSRTIMLSFFNFFQTFGVYGFGAWVPVLLYTKGITITHS
LLYTMVIAFATPLGALGAMACAERIQRKWQLVGCAIVVAVAGVLFGMVREPLLILLFGSAVTIANNWLIGIFHTYQAELY
PTRIRARAVGFVFSWSRLSSIFVGFWVAALLKHSGVPAVFVLISSAMFVIVVMVGLLGPKTNGIRLEELSQ
>Mature_471_residues
MYMEKEIAGTAGVQASVSARLDRLPPTRYFSGLVARIAIGGWFEFYEMFMAAYISLGLISSGLYRATTAGLFDVDGFASF
LGSFFAGMFVGTVALGGFTDRFGRRAVFTCAMLIYSVATFAAAFQHSPQAMDLWRFVAGLGIGVQLITVDTYISELTPHH
TRGRYSAFSILVILTSVPTVAVLSFLLVPHTILGLEGWRWVMIIGSAGAVLIWFMRRGLPESPRWLESKGRLDEARAIVD
AIEARVVAETGRALQAPAQRAPQPLTGEHGGSWSEMWKGRYLSRTIMLSFFNFFQTFGVYGFGAWVPVLLYTKGITITHS
LLYTMVIAFATPLGALGAMACAERIQRKWQLVGCAIVVAVAGVLFGMVREPLLILLFGSAVTIANNWLIGIFHTYQAELY
PTRIRARAVGFVFSWSRLSSIFVGFWVAALLKHSGVPAVFVLISSAMFVIVVMVGLLGPKTNGIRLEELSQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI166064021, Length=397, Percent_Identity=23.6775818639798, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI203098995, Length=156, Percent_Identity=31.4102564102564, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI166197673, Length=375, Percent_Identity=25.6, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI4506999, Length=414, Percent_Identity=24.3961352657005, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI262399383, Length=261, Percent_Identity=22.2222222222222, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI7662270, Length=261, Percent_Identity=22.2222222222222, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1788074, Length=470, Percent_Identity=29.3617021276596, Blast_Score=159, Evalue=5e-40,
Organism=Escherichia coli, GI1788068, Length=469, Percent_Identity=26.6524520255864, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI87082159, Length=411, Percent_Identity=27.7372262773723, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1786229, Length=437, Percent_Identity=25.1716247139588, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790463, Length=433, Percent_Identity=24.4803695150115, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082231, Length=163, Percent_Identity=28.2208588957055, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1789207, Length=273, Percent_Identity=24.5421245421245, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17565978, Length=292, Percent_Identity=25, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17560496, Length=400, Percent_Identity=23.75, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323653, Length=438, Percent_Identity=23.7442922374429, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321100, Length=419, Percent_Identity=23.6276849642005, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640198, Length=442, Percent_Identity=23.9819004524887, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640196, Length=442, Percent_Identity=23.9819004524887, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640200, Length=442, Percent_Identity=23.9819004524887, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19922616, Length=416, Percent_Identity=25.2403846153846, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 51574; Mature: 51574

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYMEKEIAGTAGVQASVSARLDRLPPTRYFSGLVARIAIGGWFEFYEMFMAAYISLGLIS
CCCCHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGLYRATTAGLFDVDGFASFLGSFFAGMFVGTVALGGFTDRFGRRAVFTCAMLIYSVATF
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AAAFQHSPQAMDLWRFVAGLGIGVQLITVDTYISELTPHHTRGRYSAFSILVILTSVPTV
HHHHHCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHH
AVLSFLLVPHTILGLEGWRWVMIIGSAGAVLIWFMRRGLPESPRWLESKGRLDEARAIVD
HHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHH
AIEARVVAETGRALQAPAQRAPQPLTGEHGGSWSEMWKGRYLSRTIMLSFFNFFQTFGVY
HHHHHHHHHCCCHHHCCHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCC
GFGAWVPVLLYTKGITITHSLLYTMVIAFATPLGALGAMACAERIQRKWQLVGCAIVVAV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGVLFGMVREPLLILLFGSAVTIANNWLIGIFHTYQAELYPTRIRARAVGFVFSWSRLSS
HHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFVGFWVAALLKHSGVPAVFVLISSAMFVIVVMVGLLGPKTNGIRLEELSQ
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHCCCC
>Mature Secondary Structure
MYMEKEIAGTAGVQASVSARLDRLPPTRYFSGLVARIAIGGWFEFYEMFMAAYISLGLIS
CCCCHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGLYRATTAGLFDVDGFASFLGSFFAGMFVGTVALGGFTDRFGRRAVFTCAMLIYSVATF
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AAAFQHSPQAMDLWRFVAGLGIGVQLITVDTYISELTPHHTRGRYSAFSILVILTSVPTV
HHHHHCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHH
AVLSFLLVPHTILGLEGWRWVMIIGSAGAVLIWFMRRGLPESPRWLESKGRLDEARAIVD
HHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHH
AIEARVVAETGRALQAPAQRAPQPLTGEHGGSWSEMWKGRYLSRTIMLSFFNFFQTFGVY
HHHHHHHHHCCCHHHCCHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCC
GFGAWVPVLLYTKGITITHSLLYTMVIAFATPLGALGAMACAERIQRKWQLVGCAIVVAV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGVLFGMVREPLLILLFGSAVTIANNWLIGIFHTYQAELYPTRIRARAVGFVFSWSRLSS
HHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFVGFWVAALLKHSGVPAVFVLISSAMFVIVVMVGLLGPKTNGIRLEELSQ
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]