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The map label for this gene is frlR [H]

Identifier: 91781742

GI number: 91781742

Start: 395251

End: 395991

Strand: Direct

Name: frlR [H]

Synonym: Bxe_A4103

Alternate gene names: 91781742

Gene position: 395251-395991 (Clockwise)

Preceding gene: 91781739

Following gene: 91781745

Centisome position: 8.07

GC content: 64.78

Gene sequence:

>741_bases
ATGCCAGGATTTCGTACTCCGGGAGAGCAACCGCTCTATGAAATCGTCCGCGCCCGTATTCTCGAGCGCCTGCGTACCGG
CCAATGGACGGCCGGCGACAAGATCCCCGCAGAGCCGCAACTGGCCGAAGAATTCGGCGTGGGCATCGGCACGATCCGCC
GCGCCGTCGAAGAACTGGTGGCCGAGCGCCTGCTGATTCGCCGCGCGGGGCGCGGCACGATCGTCGCGAAGTTCGCCGAC
GAACACGCGTTCGACCAGTACTTCAGCTTTGTCGATACGACCGGCGAGCTGATGAAGGTGACCGCGCGCCTGCTGCGCTT
TGGCAAGGAGCGCGCGAGCCCGGCGCTCGCCTCGACGCTCAGGCTCGAGCGCGGCGCACGGCTTGCCACTGCGGATAATC
TTCGGCTGCATGACGACGTTCCGGTCATGCTCGATCGCTTGTGGATGCCACTCGACGTGTTTCCGGACCTCGACGCAGGA
AAGTTCGAAGCGCGGCGCGGCTCTATCTACGGTTTTTACCAGGAGCACTTCGGGATTTCAGTCGTGCGCGTGGTGGAAGA
CCTGGGCGGCGCGGCCGCCGACGAAGAAGCGGCGCGCGCGCTCAACATTGAAGTGGGCGCGCCGGTGCTGCGCATCGAGC
GCACGGCTTACACGTTCAAGGACCAGCCGGTCGAATTTCGCGTGCGCCTTGTCGATTCGAGCCGCTGTTCCTATCGGAAC
GTGCGCGGCTTGCAGGACTGA

Upstream 100 bases:

>100_bases
GGGCCGGGGCGGCGCATGTCGTACGTGCGCTCGCGGCCATTTCATCGCGGTTCGAGCGGCTCGTTCCGACTTCTTTCTCT
TCACTCTGACACTGACCTGA

Downstream 100 bases:

>100_bases
TCGGCTATTGCCGGAACCGTGCGATCGTGCCGAGGGCCGGCTCGCCGAACACGGTTTCGCACCATCCGCGCGCCTCGTCG
GCGAGCGCGGCGTTCCAGCC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MPGFRTPGEQPLYEIVRARILERLRTGQWTAGDKIPAEPQLAEEFGVGIGTIRRAVEELVAERLLIRRAGRGTIVAKFAD
EHAFDQYFSFVDTTGELMKVTARLLRFGKERASPALASTLRLERGARLATADNLRLHDDVPVMLDRLWMPLDVFPDLDAG
KFEARRGSIYGFYQEHFGISVVRVVEDLGGAAADEEAARALNIEVGAPVLRIERTAYTFKDQPVEFRVRLVDSSRCSYRN
VRGLQD

Sequences:

>Translated_246_residues
MPGFRTPGEQPLYEIVRARILERLRTGQWTAGDKIPAEPQLAEEFGVGIGTIRRAVEELVAERLLIRRAGRGTIVAKFAD
EHAFDQYFSFVDTTGELMKVTARLLRFGKERASPALASTLRLERGARLATADNLRLHDDVPVMLDRLWMPLDVFPDLDAG
KFEARRGSIYGFYQEHFGISVVRVVEDLGGAAADEEAARALNIEVGAPVLRIERTAYTFKDQPVEFRVRLVDSSRCSYRN
VRGLQD
>Mature_245_residues
PGFRTPGEQPLYEIVRARILERLRTGQWTAGDKIPAEPQLAEEFGVGIGTIRRAVEELVAERLLIRRAGRGTIVAKFADE
HAFDQYFSFVDTTGELMKVTARLLRFGKERASPALASTLRLERGARLATADNLRLHDDVPVMLDRLWMPLDVFPDLDAGK
FEARRGSIYGFYQEHFGISVVRVVEDLGGAAADEEAARALNIEVGAPVLRIERTAYTFKDQPVEFRVRLVDSSRCSYRNV
RGLQD

Specific function: May regulate the transcription of the frlABCD operon [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082252, Length=219, Percent_Identity=31.9634703196347, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790118, Length=221, Percent_Identity=30.7692307692308, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786950, Length=204, Percent_Identity=29.4117647058824, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27664; Mature: 27533

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGFRTPGEQPLYEIVRARILERLRTGQWTAGDKIPAEPQLAEEFGVGIGTIRRAVEELV
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHH
AERLLIRRAGRGTIVAKFADEHAFDQYFSFVDTTGELMKVTARLLRFGKERASPALASTL
HHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHH
RLERGARLATADNLRLHDDVPVMLDRLWMPLDVFPDLDAGKFEARRGSIYGFYQEHFGIS
HHHCCCCEECCCCCEECCCHHHHHHHHCCCCCCCCCCCCCCCHHCCCCEEEEHHHHHCHH
VVRVVEDLGGAAADEEAARALNIEVGAPVLRIERTAYTFKDQPVEFRVRLVDSSRCSYRN
HHHHHHHHCCCCCCHHHHHEEEEECCCCEEEEEHHHHCCCCCCEEEEEEEECCCCCCHHC
VRGLQD
CCCCCC
>Mature Secondary Structure 
PGFRTPGEQPLYEIVRARILERLRTGQWTAGDKIPAEPQLAEEFGVGIGTIRRAVEELV
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHH
AERLLIRRAGRGTIVAKFADEHAFDQYFSFVDTTGELMKVTARLLRFGKERASPALASTL
HHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHH
RLERGARLATADNLRLHDDVPVMLDRLWMPLDVFPDLDAGKFEARRGSIYGFYQEHFGIS
HHHCCCCEECCCCCEECCCHHHHHHHHCCCCCCCCCCCCCCCHHCCCCEEEEHHHHHCHH
VVRVVEDLGGAAADEEAARALNIEVGAPVLRIERTAYTFKDQPVEFRVRLVDSSRCSYRN
HHHHHHHHCCCCCCHHHHHEEEEECCCCEEEEEHHHHCCCCCCEEEEEEEECCCCCCHHC
VRGLQD
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]