Click here to switch to the map view.

The map label for this gene is lolB [H]

Identifier: 91781715

GI number: 91781715

Start: 365318

End: 365953

Strand: Reverse

Name: lolB [H]

Synonym: Bxe_A4131

Alternate gene names: 91781715

Gene position: 365953-365318 (Counterclockwise)

Preceding gene: 91781716

Following gene: 91781714

Centisome position: 7.47

GC content: 65.88

Gene sequence:

>636_bases
ATGCGTCTTTCCCGTCTGATTTCCTTTCCCCGGGCGCCGCGTGGCGCGGCGCTCGGATTCGCAGCGGCGGCGGTTGTCGC
ATTGGCCGGTTGTGCGTCGGTGAAACCGCAGGGGCCATCCACGTCGAATGCCGCAACCTCCGTCACCGCGCAGACGAGCC
GTTCTTACCAGGGCCGTTTCGCGGTCCAGTACAACGATCAGAACGGCCAGCAGCGCAACGCCTACGGCAATTTCGCCTGG
CAGGAAACCGGCGATACCGTGACTCTGGAGTTACGCAATCCGCTCGGCCAGACGCTGGCGGTGGTGACGTCGTCGCCAGC
GTCGGCCACGCTGGAGTTGCCGAATCGCCAGCCGCTCACCGCGGACAACGTCTCCACGCTGATGCAGAATGCGCTCGGCT
TCGCACTGCCGGTCGAGGGGCTGCGCTACTGGCTGCAACCGTCGCCGGCACCCACTTCGCGCGCCAGGACCGAGAAGGAT
CCCGACCAGCCGTCGCGGCTGAAAGAGATCACGCAGGACGGCTGGACGATCGACTACCTGGCGTATGTCGAGCCGCCTGC
CACGGGCGTGAAGCGCGTCAACCTGACGCGCTCGGAGCCGCCGCTCGACATCAAGCTCGTCCTGGATCATCAGTAA

Upstream 100 bases:

>100_bases
AGGATCAGGCCCGCGCCGCTTTCCGCGACGCGCGCAAGCTCGAACCGGACAACGACACGCTGGTCAAAACGCTCCAACGT
CTTCAGGTGAACGATCTTTG

Downstream 100 bases:

>100_bases
CCGGTGCCGCTTCACGCACCTTTCACGCATCTTTTTCGCGCGCGACCTTGCCGCTTCTTCAGCGCCACGTGGCGCATGTA
GCCTCGACTCATGATTGAAA

Product: outer membrane lipoprotein LolB

Products: 5-aminolevulinate; CoA; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MRLSRLISFPRAPRGAALGFAAAAVVALAGCASVKPQGPSTSNAATSVTAQTSRSYQGRFAVQYNDQNGQQRNAYGNFAW
QETGDTVTLELRNPLGQTLAVVTSSPASATLELPNRQPLTADNVSTLMQNALGFALPVEGLRYWLQPSPAPTSRARTEKD
PDQPSRLKEITQDGWTIDYLAYVEPPATGVKRVNLTRSEPPLDIKLVLDHQ

Sequences:

>Translated_211_residues
MRLSRLISFPRAPRGAALGFAAAAVVALAGCASVKPQGPSTSNAATSVTAQTSRSYQGRFAVQYNDQNGQQRNAYGNFAW
QETGDTVTLELRNPLGQTLAVVTSSPASATLELPNRQPLTADNVSTLMQNALGFALPVEGLRYWLQPSPAPTSRARTEKD
PDQPSRLKEITQDGWTIDYLAYVEPPATGVKRVNLTRSEPPLDIKLVLDHQ
>Mature_211_residues
MRLSRLISFPRAPRGAALGFAAAAVVALAGCASVKPQGPSTSNAATSVTAQTSRSYQGRFAVQYNDQNGQQRNAYGNFAW
QETGDTVTLELRNPLGQTLAVVTSSPASATLELPNRQPLTADNVSTLMQNALGFALPVEGLRYWLQPSPAPTSRARTEKD
PDQPSRLKEITQDGWTIDYLAYVEPPATGVKRVNLTRSEPPLDIKLVLDHQ

Specific function: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein [H]

COG id: COG3017

COG function: function code M; Outer membrane lipoprotein involved in outer membrane biogenesis

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolB family [H]

Homologues:

Organism=Escherichia coli, GI1787460, Length=169, Percent_Identity=30.1775147928994, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004565 [H]

Pfam domain/function: PF03550 LolB [H]

EC number: NA

Molecular weight: Translated: 22791; Mature: 22791

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSRLISFPRAPRGAALGFAAAAVVALAGCASVKPQGPSTSNAATSVTAQTSRSYQGRF
CCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCEE
AVQYNDQNGQQRNAYGNFAWQETGDTVTLELRNPLGQTLAVVTSSPASATLELPNRQPLT
EEEECCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCEEEEEECCCCCEEEECCCCCCCC
ADNVSTLMQNALGFALPVEGLRYWLQPSPAPTSRARTEKDPDQPSRLKEITQDGWTIDYL
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEE
AYVEPPATGVKRVNLTRSEPPLDIKLVLDHQ
EEECCCCCCCEEEEECCCCCCEEEEEEEECC
>Mature Secondary Structure
MRLSRLISFPRAPRGAALGFAAAAVVALAGCASVKPQGPSTSNAATSVTAQTSRSYQGRF
CCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCEE
AVQYNDQNGQQRNAYGNFAWQETGDTVTLELRNPLGQTLAVVTSSPASATLELPNRQPLT
EEEECCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCEEEEEECCCCCEEEECCCCCCCC
ADNVSTLMQNALGFALPVEGLRYWLQPSPAPTSRARTEKDPDQPSRLKEITQDGWTIDYL
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEE
AYVEPPATGVKRVNLTRSEPPLDIKLVLDHQ
EEECCCCCCCEEEEECCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Succinyl-CoA; glycine [C]

Specific reaction: Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2 [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA