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The map label for this gene is hisC1 [H]

Identifier: 91781710

GI number: 91781710

Start: 360527

End: 361606

Strand: Reverse

Name: hisC1 [H]

Synonym: Bxe_A4136

Alternate gene names: 91781710

Gene position: 361606-360527 (Counterclockwise)

Preceding gene: 91781711

Following gene: 91781706

Centisome position: 7.39

GC content: 62.69

Gene sequence:

>1080_bases
TTGAGCCGTTATTGGAGTGACATCGTTCACCGTCTGACGCCATATGTGCCTGGCGAGCAGCCCGTGGTTACGCATCCGGT
GAAGCTGAATACCAACGAGAATCCGTATCCGCCGTCGCCTCGTGTGCTCGAAGCGATCCGGCAGGAACTGGGCGACGCAG
CCGAATCGCTGCGCCGCTACCCCGATCCGACGGCGCAAAAGCTCCGCGAAACGGTTGCCGCGTACCACGGCATCCGCGCC
GAGCAGGTCTTTGCGGGCAACGGCTCGGACGAAGTGCTCGCGCTCACGTTCCAGGCACTGCTCAAGCACGACAAGCCGCT
GCTGTTTCCGGACGTCACCTACAGCTTCTATCCGACGTACGCGCGGCTGTTCGAAGTCGACTACCGGACTATCCCGCTCG
ACGATAGCTTCACGATCCACGTCGACGATTACATGTCGCCGAACGGCGGCATCCTGTTCCCGAATCCGAATGCGCCGACC
GGCCGCCCGCTGCCGCTTGCCGATATCGAGCGCCTGGTGGCGAGCAGTCCCGATTCCGTGGTGGTGATCGACGAAGCGTA
CGTGGATTTCGGCGCGCAGTCGGCCATCGGTTTGATCGATCGCTATCCGAATCTGCTGGTCGTTCAGACCGTATCGAAGT
CGCGTTCGCTGGCCGGGATGCGCGTCGGCTTTGCGTTCGGCAATCCGGACCTGATCGGCGCGCTGAACCGTGTAAAGGAC
AGCTTCAACTCCTATCCGTTAGACCGCCTCGCGCAGGCTGCCGCCGCGGCGGCGTACGAAGACGACGCATGGTTTCGCGA
CACGTGCGCCAAGGTCGTGGCGAGCCGTGAACGACTGGCGGCCGGGCTGACGGCGCTGGGCTTCGAGGTGCTGCCGTCGG
CCGCGAATCTGCTGTTCGCACGCCACGAAGGCTACGACGCCGCAACGCTCGCATTGCGGTTGAGGGACAAGGAAATTTTC
GTGCGCCATTTCAAGGCTCCGCGAATCGACCAGCATTTGCGGATCTCAGTCGGGACGGACGCCGAATGCGACATTCTTCT
GGACGCGCTGCGGGACATCTTCAGCGCTTACGTCGGTTAA

Upstream 100 bases:

>100_bases
CGCGATGATGCAACTGCATCGCAATCCGTAGGCGGCGCCTCTGCCGGAACCGGGCTGCCGTGCCGCCATCGACCGTAACT
TTCCTGCTTGGGAGAATCGC

Downstream 100 bases:

>100_bases
CACGACGAACAGCGCAGAAACGTTGCGGCAAAAAAAAACGGCGAGGCCGAAAGGTCTCGCCGTTTTTTTAGACTTCGAAC
TTCACTCGCCCTTTGCAGCC

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 1 [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MSRYWSDIVHRLTPYVPGEQPVVTHPVKLNTNENPYPPSPRVLEAIRQELGDAAESLRRYPDPTAQKLRETVAAYHGIRA
EQVFAGNGSDEVLALTFQALLKHDKPLLFPDVTYSFYPTYARLFEVDYRTIPLDDSFTIHVDDYMSPNGGILFPNPNAPT
GRPLPLADIERLVASSPDSVVVIDEAYVDFGAQSAIGLIDRYPNLLVVQTVSKSRSLAGMRVGFAFGNPDLIGALNRVKD
SFNSYPLDRLAQAAAAAAYEDDAWFRDTCAKVVASRERLAAGLTALGFEVLPSAANLLFARHEGYDAATLALRLRDKEIF
VRHFKAPRIDQHLRISVGTDAECDILLDALRDIFSAYVG

Sequences:

>Translated_359_residues
MSRYWSDIVHRLTPYVPGEQPVVTHPVKLNTNENPYPPSPRVLEAIRQELGDAAESLRRYPDPTAQKLRETVAAYHGIRA
EQVFAGNGSDEVLALTFQALLKHDKPLLFPDVTYSFYPTYARLFEVDYRTIPLDDSFTIHVDDYMSPNGGILFPNPNAPT
GRPLPLADIERLVASSPDSVVVIDEAYVDFGAQSAIGLIDRYPNLLVVQTVSKSRSLAGMRVGFAFGNPDLIGALNRVKD
SFNSYPLDRLAQAAAAAAYEDDAWFRDTCAKVVASRERLAAGLTALGFEVLPSAANLLFARHEGYDAATLALRLRDKEIF
VRHFKAPRIDQHLRISVGTDAECDILLDALRDIFSAYVG
>Mature_358_residues
SRYWSDIVHRLTPYVPGEQPVVTHPVKLNTNENPYPPSPRVLEAIRQELGDAAESLRRYPDPTAQKLRETVAAYHGIRAE
QVFAGNGSDEVLALTFQALLKHDKPLLFPDVTYSFYPTYARLFEVDYRTIPLDDSFTIHVDDYMSPNGGILFPNPNAPTG
RPLPLADIERLVASSPDSVVVIDEAYVDFGAQSAIGLIDRYPNLLVVQTVSKSRSLAGMRVGFAFGNPDLIGALNRVKDS
FNSYPLDRLAQAAAAAAYEDDAWFRDTCAKVVASRERLAAGLTALGFEVLPSAANLLFARHEGYDAATLALRLRDKEIFV
RHFKAPRIDQHLRISVGTDAECDILLDALRDIFSAYVG

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=354, Percent_Identity=31.0734463276836, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788722, Length=230, Percent_Identity=30.8695652173913, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322075, Length=381, Percent_Identity=28.0839895013123, Blast_Score=117, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 39737; Mature: 39606

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYWSDIVHRLTPYVPGEQPVVTHPVKLNTNENPYPPSPRVLEAIRQELGDAAESLRRY
CCHHHHHHHHHHCCCCCCCCCEEECCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
PDPTAQKLRETVAAYHGIRAEQVFAGNGSDEVLALTFQALLKHDKPLLFPDVTYSFYPTY
CCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
ARLFEVDYRTIPLDDSFTIHVDDYMSPNGGILFPNPNAPTGRPLPLADIERLVASSPDSV
HHHEECCCEEECCCCCEEEEECCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCE
VVIDEAYVDFGAQSAIGLIDRYPNLLVVQTVSKSRSLAGMRVGFAFGNPDLIGALNRVKD
EEEEHHHHCCCCHHHHHHHHCCCCEEEEEEHHHCCCCCCEEEEEEECCCHHHHHHHHHHH
SFNSYPLDRLAQAAAAAAYEDDAWFRDTCAKVVASRERLAAGLTALGFEVLPSAANLLFA
HHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
RHEGYDAATLALRLRDKEIFVRHFKAPRIDQHLRISVGTDAECDILLDALRDIFSAYVG
CCCCCCEEEEEEEECCHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRYWSDIVHRLTPYVPGEQPVVTHPVKLNTNENPYPPSPRVLEAIRQELGDAAESLRRY
CHHHHHHHHHHCCCCCCCCCEEECCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
PDPTAQKLRETVAAYHGIRAEQVFAGNGSDEVLALTFQALLKHDKPLLFPDVTYSFYPTY
CCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
ARLFEVDYRTIPLDDSFTIHVDDYMSPNGGILFPNPNAPTGRPLPLADIERLVASSPDSV
HHHEECCCEEECCCCCEEEEECCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCE
VVIDEAYVDFGAQSAIGLIDRYPNLLVVQTVSKSRSLAGMRVGFAFGNPDLIGALNRVKD
EEEEHHHHCCCCHHHHHHHHCCCCEEEEEEHHHCCCCCCEEEEEEECCCHHHHHHHHHHH
SFNSYPLDRLAQAAAAAAYEDDAWFRDTCAKVVASRERLAAGLTALGFEVLPSAANLLFA
HHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
RHEGYDAATLALRLRDKEIFVRHFKAPRIDQHLRISVGTDAECDILLDALRDIFSAYVG
CCCCCCEEEEEEEECCHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA