Click here to switch to the map view.

The map label for this gene is gpmA [H]

Identifier: 91781665

GI number: 91781665

Start: 317805

End: 318551

Strand: Reverse

Name: gpmA [H]

Synonym: Bxe_A4181

Alternate gene names: 91781665

Gene position: 318551-317805 (Counterclockwise)

Preceding gene: 91781671

Following gene: 91781664

Centisome position: 6.51

GC content: 62.65

Gene sequence:

>747_bases
ATGTACAAACTCGTTCTCATCCGCCACGGCGAATCGACGTGGAACAAGGAAAACCGCTTCACGGGCTGGGTCGACGTCGA
CCTCACCGAGCAGGGCAACAATGAGGCGCAGCAAGCGGGCGTGCTGCTGAAGGATTCGGGCTACACGTTCGACATCGCCT
ACACGTCGGTGCTCAAGCGCGCGATCCGCACCTTGTGGCACGTGCAGGACAAGATGGATCTGATGTACCTGCCGGTGGTC
CATTCGTGGCGTCTGAACGAACGGCACTACGGTGCGCTGTCGGGTCTGAACAAGGCTGAGACGGCCGCCAGATTCGGCGA
CGAACAGGTGCTGGTCTGGCGCCGCAGCTACGACACGCCGCCGCCCGCTCTCGAGCCGACGGACGAGCGCGCGCCCTACA
ACGATCCGCGCTACGCCAAAGTGCCGCGCGAACAGTTGCCGCTCACCGAATGCCTGAAGGACACGGTCGCGCGCGTTCTG
CCCCTGTGGAACGAGTCGATTGCGCCGGCCATCAAGTCGGGCCGCCAGGTGCTGATCGCCGCCCACGGCAATTCGATCCG
CGCGCTCGTCAAATACCTCGACGATATTTCGGACAACGACATCGTCGGTCTGAATATTCCGAACGGCGTGCCGCTCGTTT
ACGAACTCGACGAAAACCTGCGGCCAATCAAGCACTACTATCTGGGCGACCAGGAAGCGATCGCCAAGGCGCAGGCCGCA
GTCGCCAGGCAGGGAAAGGCAGGCTGA

Upstream 100 bases:

>100_bases
CAATCCACCCATTATAAAATAACCGTCTGACGCGATGGCGGCGCTCCTCCGGAGGACCCCGCAGCGCTTTACCGCTTCCT
CACTACCGACCGGCAATCTC

Downstream 100 bases:

>100_bases
TTTGCCATCTCGCCGCCATGTTGCCGTCAGAAACGAAGCGAATGGCGGCTAACGGCCGCACCGACCGGCAAGACATACCG
GTCGGCGCGGCTCGCCTCAT

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNNEAQQAGVLLKDSGYTFDIAYTSVLKRAIRTLWHVQDKMDLMYLPVV
HSWRLNERHYGALSGLNKAETAARFGDEQVLVWRRSYDTPPPALEPTDERAPYNDPRYAKVPREQLPLTECLKDTVARVL
PLWNESIAPAIKSGRQVLIAAHGNSIRALVKYLDDISDNDIVGLNIPNGVPLVYELDENLRPIKHYYLGDQEAIAKAQAA
VARQGKAG

Sequences:

>Translated_248_residues
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNNEAQQAGVLLKDSGYTFDIAYTSVLKRAIRTLWHVQDKMDLMYLPVV
HSWRLNERHYGALSGLNKAETAARFGDEQVLVWRRSYDTPPPALEPTDERAPYNDPRYAKVPREQLPLTECLKDTVARVL
PLWNESIAPAIKSGRQVLIAAHGNSIRALVKYLDDISDNDIVGLNIPNGVPLVYELDENLRPIKHYYLGDQEAIAKAQAA
VARQGKAG
>Mature_248_residues
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNNEAQQAGVLLKDSGYTFDIAYTSVLKRAIRTLWHVQDKMDLMYLPVV
HSWRLNERHYGALSGLNKAETAARFGDEQVLVWRRSYDTPPPALEPTDERAPYNDPRYAKVPREQLPLTECLKDTVARVL
PLWNESIAPAIKSGRQVLIAAHGNSIRALVKYLDDISDNDIVGLNIPNGVPLVYELDENLRPIKHYYLGDQEAIAKAQAA
VARQGKAG

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=252, Percent_Identity=57.9365079365079, Blast_Score=310, Evalue=6e-85,
Organism=Homo sapiens, GI4505753, Length=249, Percent_Identity=61.0441767068273, Blast_Score=301, Evalue=3e-82,
Organism=Homo sapiens, GI71274132, Length=249, Percent_Identity=59.0361445783133, Blast_Score=288, Evalue=2e-78,
Organism=Homo sapiens, GI4502445, Length=254, Percent_Identity=51.5748031496063, Blast_Score=263, Evalue=9e-71,
Organism=Homo sapiens, GI40353764, Length=254, Percent_Identity=51.5748031496063, Blast_Score=263, Evalue=9e-71,
Organism=Homo sapiens, GI310129614, Length=162, Percent_Identity=62.3456790123457, Blast_Score=197, Evalue=1e-50,
Organism=Escherichia coli, GI1786970, Length=245, Percent_Identity=65.7142857142857, Blast_Score=331, Evalue=2e-92,
Organism=Saccharomyces cerevisiae, GI6322697, Length=246, Percent_Identity=52.8455284552846, Blast_Score=243, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6324516, Length=286, Percent_Identity=32.1678321678322, Blast_Score=146, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6320183, Length=294, Percent_Identity=31.2925170068027, Blast_Score=135, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24646216, Length=250, Percent_Identity=53.6, Blast_Score=276, Evalue=6e-75,
Organism=Drosophila melanogaster, GI85725270, Length=250, Percent_Identity=52.8, Blast_Score=265, Evalue=3e-71,
Organism=Drosophila melanogaster, GI85725272, Length=250, Percent_Identity=52.8, Blast_Score=265, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24650981, Length=250, Percent_Identity=52.8, Blast_Score=265, Evalue=3e-71,
Organism=Drosophila melanogaster, GI28571815, Length=251, Percent_Identity=42.2310756972112, Blast_Score=187, Evalue=8e-48,
Organism=Drosophila melanogaster, GI28571817, Length=251, Percent_Identity=42.2310756972112, Blast_Score=186, Evalue=9e-48,
Organism=Drosophila melanogaster, GI24648979, Length=251, Percent_Identity=42.2310756972112, Blast_Score=186, Evalue=1e-47,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 28035; Mature: 28035

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNNEAQQAGVLLKDSGYTFDIAYTSVLKR
CEEEEEEECCCCCCCCCCCEEEEEEEEECCCCCCHHHHCCEEEECCCCEEEHHHHHHHHH
AIRTLWHVQDKMDLMYLPVVHSWRLNERHYGALSGLNKAETAARFGDEQVLVWRRSYDTP
HHHHHHHHHHCCCEEEECEEECEECCCCCCHHHHCCCHHHHHHHCCCCEEEEEEECCCCC
PPALEPTDERAPYNDPRYAKVPREQLPLTECLKDTVARVLPLWNESIAPAIKSGRQVLIA
CCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEE
AHGNSIRALVKYLDDISDNDIVGLNIPNGVPLVYELDENLRPIKHYYLGDQEAIAKAQAA
ECCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHHCCCHHHHHHHHHH
VARQGKAG
HHHCCCCC
>Mature Secondary Structure
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNNEAQQAGVLLKDSGYTFDIAYTSVLKR
CEEEEEEECCCCCCCCCCCEEEEEEEEECCCCCCHHHHCCEEEECCCCEEEHHHHHHHHH
AIRTLWHVQDKMDLMYLPVVHSWRLNERHYGALSGLNKAETAARFGDEQVLVWRRSYDTP
HHHHHHHHHHCCCEEEECEEECEECCCCCCHHHHCCCHHHHHHHCCCCEEEEEEECCCCC
PPALEPTDERAPYNDPRYAKVPREQLPLTECLKDTVARVLPLWNESIAPAIKSGRQVLIA
CCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEE
AHGNSIRALVKYLDDISDNDIVGLNIPNGVPLVYELDENLRPIKHYYLGDQEAIAKAQAA
ECCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHHCCCHHHHHHHHHH
VARQGKAG
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA