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The map label for this gene is moeB [H]

Identifier: 91781663

GI number: 91781663

Start: 314961

End: 315719

Strand: Reverse

Name: moeB [H]

Synonym: Bxe_A4183

Alternate gene names: 91781663

Gene position: 315719-314961 (Counterclockwise)

Preceding gene: 91781664

Following gene: 91781655

Centisome position: 6.45

GC content: 64.16

Gene sequence:

>759_bases
ATGAACGACGATCAACTCCTTCGCTATTCCCGCCATATCCTCGTCGACGAAATCGGCATCGAGGCGCAGCAGCGTTTTAT
CGACGCGCACGCGATCATCGTCGGTGCGGGCGGTCTGGGTTCACCCGCTGCGATGTACCTCGCCGCAGCGGGCGTCGGCC
GCCTGACGCTGGTCGATGCCGATACGGTCGATCTGACCAATCTGCAACGGCAGATCCTGCATGTGACCGCATCTGTCGGG
CGCAAGAAGGTGGAGTCCGGGCGGGACGCGATCGCGCGGATCAATCCCGAGGTCGTGGTGAACGCAGTGGCCGAGCGCGT
CGACGACGCGTGGCTCGACGCGCAAGTCCCGCATGCCACGGTCGTGCTCGACTGCACCGATAACTTCGCGACGCGCCACG
CGATCAACCGCGCGTGCGTGAAGCACGGCGTGCCGCTCGTATCGGGTGCGGCGTTGCGCTTTGACGGCCAGATCAGCACC
TTCGATTTCCGCGACGAAGCGTCGCCCTGCTATGCATGCGTGTTTCCCGAAGACCAGCCCTTCGAGGAAGTCGCGTGTTC
GACTATGGGCGTGTTCGCGCCGACAGTCGGCATCGTGGGTTCGATGCAGGCCGCCGAAGCGCTCAAGGTGATCGGCGGAA
TCGGCACGCCTTTGCTTGGCCGCCTGATGATGCTCGATTCGTTGCGCATGGAATGGAACACCATGCGCATCGCGCGTCAG
CCGGATTGCCCGGTGTGCGGGCAGACACACGCGGTCTGA

Upstream 100 bases:

>100_bases
CAGGAACACCCGCTCCCCCGCGCGATTAAAATAACGAAACCGCGCACGGCAGGCCCATCGGACCTGCATCTCATCGCGCG
ACACACTCACGCGCCCCGCC

Downstream 100 bases:

>100_bases
TTTCGTGCATCGAGGCTGTCGATGCAATCAAGGCTGAAAAAGAAATGCCGCCCATAAGGCGGCGTTTCTCATTCGAAGAC
GTGAATCCGGCAACTCACGC

Product: putative molybdopterin biosynthesis protein

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MNDDQLLRYSRHILVDEIGIEAQQRFIDAHAIIVGAGGLGSPAAMYLAAAGVGRLTLVDADTVDLTNLQRQILHVTASVG
RKKVESGRDAIARINPEVVVNAVAERVDDAWLDAQVPHATVVLDCTDNFATRHAINRACVKHGVPLVSGAALRFDGQIST
FDFRDEASPCYACVFPEDQPFEEVACSTMGVFAPTVGIVGSMQAAEALKVIGGIGTPLLGRLMMLDSLRMEWNTMRIARQ
PDCPVCGQTHAV

Sequences:

>Translated_252_residues
MNDDQLLRYSRHILVDEIGIEAQQRFIDAHAIIVGAGGLGSPAAMYLAAAGVGRLTLVDADTVDLTNLQRQILHVTASVG
RKKVESGRDAIARINPEVVVNAVAERVDDAWLDAQVPHATVVLDCTDNFATRHAINRACVKHGVPLVSGAALRFDGQIST
FDFRDEASPCYACVFPEDQPFEEVACSTMGVFAPTVGIVGSMQAAEALKVIGGIGTPLLGRLMMLDSLRMEWNTMRIARQ
PDCPVCGQTHAV
>Mature_252_residues
MNDDQLLRYSRHILVDEIGIEAQQRFIDAHAIIVGAGGLGSPAAMYLAAAGVGRLTLVDADTVDLTNLQRQILHVTASVG
RKKVESGRDAIARINPEVVVNAVAERVDDAWLDAQVPHATVVLDCTDNFATRHAINRACVKHGVPLVSGAALRFDGQIST
FDFRDEASPCYACVFPEDQPFEEVACSTMGVFAPTVGIVGSMQAAEALKVIGGIGTPLLGRLMMLDSLRMEWNTMRIARQ
PDCPVCGQTHAV

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=254, Percent_Identity=41.7322834645669, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI4885649, Length=167, Percent_Identity=27.5449101796407, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1787048, Length=251, Percent_Identity=46.2151394422311, Blast_Score=238, Evalue=2e-64,
Organism=Escherichia coli, GI87082356, Length=251, Percent_Identity=43.8247011952191, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1789177, Length=132, Percent_Identity=38.6363636363636, Blast_Score=74, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17540406, Length=263, Percent_Identity=39.5437262357414, Blast_Score=197, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI193203301, Length=165, Percent_Identity=26.0606060606061, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321903, Length=256, Percent_Identity=35.546875, Blast_Score=160, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6320598, Length=148, Percent_Identity=26.3513513513513, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582879, Length=248, Percent_Identity=40.7258064516129, Blast_Score=191, Evalue=6e-49,
Organism=Drosophila melanogaster, GI24660640, Length=158, Percent_Identity=29.1139240506329, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR012730
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 27078; Mature: 27078

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDDQLLRYSRHILVDEIGIEAQQRFIDAHAIIVGAGGLGSPAAMYLAAAGVGRLTLVDA
CCCHHHHHHHHHHHHHHHCHHHHHHHHHEEEEEEECCCCCCHHHHHHHHCCCCEEEEEEC
DTVDLTNLQRQILHVTASVGRKKVESGRDAIARINPEVVVNAVAERVDDAWLDAQVPHAT
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEE
VVLDCTDNFATRHAINRACVKHGVPLVSGAALRFDGQISTFDFRDEASPCYACVFPEDQP
EEEECCCCHHHHHHHHHHHHHCCCCEECCCEEEECCCEEEEECCCCCCCEEEEECCCCCC
FEEVACSTMGVFAPTVGIVGSMQAAEALKVIGGIGTPLLGRLMMLDSLRMEWNTMRIARQ
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEECC
PDCPVCGQTHAV
CCCCCCCCCCCC
>Mature Secondary Structure
MNDDQLLRYSRHILVDEIGIEAQQRFIDAHAIIVGAGGLGSPAAMYLAAAGVGRLTLVDA
CCCHHHHHHHHHHHHHHHCHHHHHHHHHEEEEEEECCCCCCHHHHHHHHCCCCEEEEEEC
DTVDLTNLQRQILHVTASVGRKKVESGRDAIARINPEVVVNAVAERVDDAWLDAQVPHAT
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEE
VVLDCTDNFATRHAINRACVKHGVPLVSGAALRFDGQISTFDFRDEASPCYACVFPEDQP
EEEECCCCHHHHHHHHHHHHHCCCCEECCCEEEECCCEEEEECCCCCCCEEEEECCCCCC
FEEVACSTMGVFAPTVGIVGSMQAAEALKVIGGIGTPLLGRLMMLDSLRMEWNTMRIARQ
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEECC
PDCPVCGQTHAV
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3045084; 8905232; 9278503 [H]