Definition Burkholderia xenovorans LB400 chromosome 1, complete sequence.
Accession NC_007951
Length 4,895,836

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The map label for this gene is ucpA [C]

Identifier: 91781598

GI number: 91781598

Start: 248577

End: 249356

Strand: Reverse

Name: ucpA [C]

Synonym: Bxe_A4248

Alternate gene names: 91781598

Gene position: 249356-248577 (Counterclockwise)

Preceding gene: 91781599

Following gene: 91781597

Centisome position: 5.09

GC content: 68.33

Gene sequence:

>780_bases
ATGAGTTCACCGTTGAAGGTTTTCATTACCGGCGCCTCGAGCGGCATCGGCCTCGCGCTCGCGGCCGAATATGCGCGGCG
CGGCGCGGTTCTCGGCCTCGTGGCCCGCCGCGGCGACGCCCTCGCCGCCTTCCAGCAGTCCCATCCGCAGAGCACCGTCT
CCACCTATTCCGTCGACGTTCGCGACGCCGAAGCGCTCGCCGACGCGGCCGCGCAATTCATCGCGCAGCACGGCTTGCCG
GACGTCGTGATCGCCAACGCCGGCGTCAGCCGCGGTGCGGTCACCGGCCACGGCGACCTGCGCACCTTCCGCGAAGTGAT
GGATATCAACTACTTCGGCATGGTCGCCACGTTCGAGCCATTCGCCGCCGCGATGAGCGCCGCGAGACACGGCACGCTGG
TGGGAATCGCCAGCGTCGCCGGTGTGCGCGGCTTGCCGGGCTCCGGCGCGTACAGCGCGTCGAAATCGGCGGCGCTCAAG
TATCTGGAAGCGTTGCGCGTCGAAATGCGGCCGCACGGCGTCGGCGTGGTCACCATTGCGCCCGGCTATATCCGCACGCC
CATGACCGAGCACAACCCATACACCATGCCGTTCCTGATGGATGCCGACCGTTTCGCCGTGAAGGTGGCGCAGGCAATCG
AGCGTCAAACGGCCTTCGCGGTGTTCCCCTGGCAGATGCGCATCGTGGCCATGCTGCTGCATGTGCTGCCGCGCTGGCTC
TACGACCGTGCGTTCGAGCGCGCGCCGCGCAAGCCGCGCACCGCCGCCGAGGTCGAGTAA

Upstream 100 bases:

>100_bases
CGGCCCCGCCGCCACCAACAGCCTGCCGGGCACGATCCAGGTGCTGGATTACCTGGTCGCGCAAGTCCGCGCCAAGAAGA
TGTAAAGCCAGGGCGCCGGA

Downstream 100 bases:

>100_bases
GCCATGCAACCGGGTGCGGTCGATGCAGCCGGCGTCGCGCACGAACCCGCAGGACCCGCGGCACGTATCGTCTCGCTGGT
GCCGAGCATCACCGAACTGC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSSPLKVFITGASSGIGLALAAEYARRGAVLGLVARRGDALAAFQQSHPQSTVSTYSVDVRDAEALADAAAQFIAQHGLP
DVVIANAGVSRGAVTGHGDLRTFREVMDINYFGMVATFEPFAAAMSAARHGTLVGIASVAGVRGLPGSGAYSASKSAALK
YLEALRVEMRPHGVGVVTIAPGYIRTPMTEHNPYTMPFLMDADRFAVKVAQAIERQTAFAVFPWQMRIVAMLLHVLPRWL
YDRAFERAPRKPRTAAEVE

Sequences:

>Translated_259_residues
MSSPLKVFITGASSGIGLALAAEYARRGAVLGLVARRGDALAAFQQSHPQSTVSTYSVDVRDAEALADAAAQFIAQHGLP
DVVIANAGVSRGAVTGHGDLRTFREVMDINYFGMVATFEPFAAAMSAARHGTLVGIASVAGVRGLPGSGAYSASKSAALK
YLEALRVEMRPHGVGVVTIAPGYIRTPMTEHNPYTMPFLMDADRFAVKVAQAIERQTAFAVFPWQMRIVAMLLHVLPRWL
YDRAFERAPRKPRTAAEVE
>Mature_258_residues
SSPLKVFITGASSGIGLALAAEYARRGAVLGLVARRGDALAAFQQSHPQSTVSTYSVDVRDAEALADAAAQFIAQHGLPD
VVIANAGVSRGAVTGHGDLRTFREVMDINYFGMVATFEPFAAAMSAARHGTLVGIASVAGVRGLPGSGAYSASKSAALKY
LEALRVEMRPHGVGVVTIAPGYIRTPMTEHNPYTMPFLMDADRFAVKVAQAIERQTAFAVFPWQMRIVAMLLHVLPRWLY
DRAFERAPRKPRTAAEVE

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=34.375, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI40807363, Length=246, Percent_Identity=32.1138211382114, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=27.6041666666667, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4503817, Length=199, Percent_Identity=32.6633165829146, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI157739938, Length=187, Percent_Identity=29.9465240641711, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI310128830, Length=255, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI310115468, Length=255, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI150247226, Length=213, Percent_Identity=32.3943661971831, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI210032110, Length=238, Percent_Identity=25.6302521008403, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI223718074, Length=193, Percent_Identity=33.160621761658, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI7657478, Length=192, Percent_Identity=29.6875, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI142976729, Length=237, Percent_Identity=24.0506329113924, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI31543615, Length=226, Percent_Identity=24.7787610619469, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI87082100, Length=192, Percent_Identity=33.8541666666667, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787335, Length=183, Percent_Identity=28.4153005464481, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786701, Length=191, Percent_Identity=32.9842931937173, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787820, Length=179, Percent_Identity=24.5810055865922, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790717, Length=190, Percent_Identity=26.8421052631579, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=243, Percent_Identity=28.8065843621399, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI71997402, Length=258, Percent_Identity=28.2945736434109, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17567345, Length=191, Percent_Identity=26.7015706806283, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17507613, Length=191, Percent_Identity=29.8429319371728, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32563809, Length=193, Percent_Identity=29.5336787564767, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17570069, Length=186, Percent_Identity=32.7956989247312, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=241, Percent_Identity=28.2157676348548, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=204, Percent_Identity=29.4117647058824, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI115534660, Length=192, Percent_Identity=27.0833333333333, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=244, Percent_Identity=27.4590163934426, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=244, Percent_Identity=27.4590163934426, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=191, Percent_Identity=25.130890052356, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=189, Percent_Identity=29.6296296296296, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=188, Percent_Identity=25.531914893617, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=193, Percent_Identity=26.4248704663212, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=189, Percent_Identity=29.1005291005291, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=188, Percent_Identity=25.531914893617, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=205, Percent_Identity=28.780487804878, Blast_Score=76, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6323882, Length=191, Percent_Identity=29.8429319371728, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320089, Length=188, Percent_Identity=27.1276595744681, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322227, Length=193, Percent_Identity=27.4611398963731, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21358495, Length=269, Percent_Identity=28.6245353159851, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI23397609, Length=184, Percent_Identity=33.1521739130435, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24581726, Length=212, Percent_Identity=26.4150943396226, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644339, Length=190, Percent_Identity=30.5263157894737, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21357041, Length=188, Percent_Identity=27.6595744680851, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356301, Length=198, Percent_Identity=29.7979797979798, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28571526, Length=190, Percent_Identity=28.9473684210526, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24641388, Length=195, Percent_Identity=32.8205128205128, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355631, Length=204, Percent_Identity=27.4509803921569, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24649181, Length=185, Percent_Identity=27.027027027027, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24639444, Length=184, Percent_Identity=28.804347826087, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24580925, Length=243, Percent_Identity=29.2181069958848, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007236, Length=208, Percent_Identity=29.3269230769231, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281364892, Length=216, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640442, Length=191, Percent_Identity=26.7015706806283, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27730; Mature: 27599

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MSSPLKVFITGASSGIGLALAAEYARRGAVLGLVARRGDALAAFQQSHPQSTVSTYSVDV
CCCCEEEEEEECCCCCHHHHHHHHHHCCHHEEHHHHCCCHHHHHHHCCCCCHHHEEEECC
RDAEALADAAAQFIAQHGLPDVVIANAGVSRGAVTGHGDLRTFREVMDINYFGMVATFEP
HHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
FAAAMSAARHGTLVGIASVAGVRGLPGSGAYSASKSAALKYLEALRVEMRPHGVGVVTIA
HHHHHHHHHCCCEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEC
PGYIRTPMTEHNPYTMPFLMDADRFAVKVAQAIERQTAFAVFPWQMRIVAMLLHVLPRWL
CCHHCCCCCCCCCEECCEEECCHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHH
YDRAFERAPRKPRTAAEVE
HHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SSPLKVFITGASSGIGLALAAEYARRGAVLGLVARRGDALAAFQQSHPQSTVSTYSVDV
CCCEEEEEEECCCCCHHHHHHHHHHCCHHEEHHHHCCCHHHHHHHCCCCCHHHEEEECC
RDAEALADAAAQFIAQHGLPDVVIANAGVSRGAVTGHGDLRTFREVMDINYFGMVATFEP
HHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
FAAAMSAARHGTLVGIASVAGVRGLPGSGAYSASKSAALKYLEALRVEMRPHGVGVVTIA
HHHHHHHHHCCCEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEC
PGYIRTPMTEHNPYTMPFLMDADRFAVKVAQAIERQTAFAVFPWQMRIVAMLLHVLPRWL
CCHHCCCCCCCCCEECCEEECCHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHH
YDRAFERAPRKPRTAAEVE
HHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730672 [H]