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The map label for this gene is csgA [H]

Identifier: 91781590

GI number: 91781590

Start: 239446

End: 240123

Strand: Reverse

Name: csgA [H]

Synonym: Bxe_A4256

Alternate gene names: 91781590

Gene position: 240123-239446 (Counterclockwise)

Preceding gene: 91781591

Following gene: 91781589

Centisome position: 4.9

GC content: 64.45

Gene sequence:

>678_bases
ATGAAGACTGTGTTGATCGTCGGTGCGTCGCGTGGCATTGGCCAGGAGTTTGTGCGGCAGTACAAGAAGAGCGGCTGGCG
CGCGCTCGCCACCGCCCGCGACGGCGCCGCGCTTGACGCGTTGAACGAACTCGGCGCGGAAACGTTCTCGCTCGATGTGA
GCATGCCGGAGGAAATCGCCGCGCTCGGCTGGAAGCTCGACGGTGAACGGCTCGATGCGGCGATTCTGGTGTCGGGCGTC
TACGGCCCGCGCACCGAAGGCATCGAGACGATCACCGCCGAAGACTTCGACCACGTCATGCACACCAATGTGCGCGGACC
GATGCAATTGATGCCGATCCTGCTGCCGCTCGTCGAAGAAGCGGGCGGCGTATTCGCGGTGATTTCGAGCAAGATGGGCA
GCATCGGCGACGCGAGCGGCACGACCGGCTGGCTGTATCGCGCGAGCAAGGCGGCGCTGAACGATGCGCTGAAACTCGCG
TCGCTGGAGGCAAAGCGCGCCGCGTGCATTTCGTTGCATCCGGGCTGGGTTCGCACCGACTTGGGCGGCGCGCAGGCTGC
GATCGATCCGGCGCGCAGCGTTACCGGCATGCGTGAAGTGCTCGCGCAAGCGGCGACCGAGCATGAAGCATTCAACGGCC
GGTTTTATCAGTACGACGGTACGTTACTCGACTGGTGA

Upstream 100 bases:

>100_bases
CGACGCTGTGTATCGGCGGCGGCGAAGCGACGGCAATGGGTATCGAACTCGTGTAACGCGCGTTTTCGCGGCGCTCTGTT
TTGATGGCTTGAGGTGTTCG

Downstream 100 bases:

>100_bases
GTGGAGGCTTGGATGGGAGCGGAGTTGGCGGTAAAGCGCTGACTCTGGTCGACCGCTGTGCATGGGACCAGAGTAAGCGC
TGAAGCGCTAACTCTGGTCG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKTVLIVGASRGIGQEFVRQYKKSGWRALATARDGAALDALNELGAETFSLDVSMPEEIAALGWKLDGERLDAAILVSGV
YGPRTEGIETITAEDFDHVMHTNVRGPMQLMPILLPLVEEAGGVFAVISSKMGSIGDASGTTGWLYRASKAALNDALKLA
SLEAKRAACISLHPGWVRTDLGGAQAAIDPARSVTGMREVLAQAATEHEAFNGRFYQYDGTLLDW

Sequences:

>Translated_225_residues
MKTVLIVGASRGIGQEFVRQYKKSGWRALATARDGAALDALNELGAETFSLDVSMPEEIAALGWKLDGERLDAAILVSGV
YGPRTEGIETITAEDFDHVMHTNVRGPMQLMPILLPLVEEAGGVFAVISSKMGSIGDASGTTGWLYRASKAALNDALKLA
SLEAKRAACISLHPGWVRTDLGGAQAAIDPARSVTGMREVLAQAATEHEAFNGRFYQYDGTLLDW
>Mature_225_residues
MKTVLIVGASRGIGQEFVRQYKKSGWRALATARDGAALDALNELGAETFSLDVSMPEEIAALGWKLDGERLDAAILVSGV
YGPRTEGIETITAEDFDHVMHTNVRGPMQLMPILLPLVEEAGGVFAVISSKMGSIGDASGTTGWLYRASKAALNDALKLA
SLEAKRAACISLHPGWVRTDLGGAQAAIDPARSVTGMREVLAQAATEHEAFNGRFYQYDGTLLDW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Caenorhabditis elegans, GI17558994, Length=257, Percent_Identity=29.9610894941634, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24640547, Length=251, Percent_Identity=28.6852589641434, Blast_Score=91, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24051; Mature: 24051

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVLIVGASRGIGQEFVRQYKKSGWRALATARDGAALDALNELGAETFSLDVSMPEEIA
CCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEEEECCCHHHHH
ALGWKLDGERLDAAILVSGVYGPRTEGIETITAEDFDHVMHTNVRGPMQLMPILLPLVEE
HHCCCCCHHHCCEEEEEECCCCCCCCCCEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AGGVFAVISSKMGSIGDASGTTGWLYRASKAALNDALKLASLEAKRAACISLHPGWVRTD
CCCEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEC
LGGAQAAIDPARSVTGMREVLAQAATEHEAFNGRFYQYDGTLLDW
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEECC
>Mature Secondary Structure
MKTVLIVGASRGIGQEFVRQYKKSGWRALATARDGAALDALNELGAETFSLDVSMPEEIA
CCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEEEECCCHHHHH
ALGWKLDGERLDAAILVSGVYGPRTEGIETITAEDFDHVMHTNVRGPMQLMPILLPLVEE
HHCCCCCHHHCCEEEEEECCCCCCCCCCEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AGGVFAVISSKMGSIGDASGTTGWLYRASKAALNDALKLASLEAKRAACISLHPGWVRTD
CCCEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEC
LGGAQAAIDPARSVTGMREVLAQAATEHEAFNGRFYQYDGTLLDW
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]