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The map label for this gene is bioD [H]

Identifier: 91781581

GI number: 91781581

Start: 230041

End: 230778

Strand: Reverse

Name: bioD [H]

Synonym: Bxe_A4265

Alternate gene names: 91781581

Gene position: 230778-230041 (Counterclockwise)

Preceding gene: 91781582

Following gene: 91781580

Centisome position: 4.71

GC content: 66.4

Gene sequence:

>738_bases
ATGAGTAGCACGAGTCAAAACGCACTGTCCTTATTCATCACCGGCACCGATACGGAAATCGGCAAGACGTTCGTCTCAGC
GGCGCTGTTGCGCGGCTTCGTCCGCGAAGGCCTGCAAGCGGCCGCGATGAAGCCGGTCGCAGCCGGCGCGTTCGAACTGG
ACGGCGCGCTGCACAACGAAGATGCGGATCAACTCGACGCCGCCTCGAACGTCCTGCTGCCGCCCGAGATACGCACGCCG
TATCTGCTGAAGGAACCGGCCGCGCCGCACATCGCAGCCGCGCTGGAAAACGTCACGCTGGATCTCGGCCATATCGTCGA
CTGCCACGCGCAAGCACTCAAGCGCGCGGAGATCGTCGTGGTGGAAGGCGTCGGCGGTTTTCGCGTGCCGTTGACCGCTG
CCCAGGACACCGCCGATCTCGCCGTCGCCCTGGAGCTGCCGGTGGTGCTGGTGGTGGGCATGCGGCTCGGCTGCATCAGC
CATGCGCTGCTCACCGCCGAAGCAATCGCCGCGCGCGGGCTCACGCTCGCCGGCTGGGTCGCGAACCGCATCGATCCCGA
CATGACCTTCCCCGACGAAAACATCGCGTCGATCCGCGAGCATCTCGCCCGCGCATACGACGCGCCGCTGCTCGGCATCG
TGCCGCATCTGAACCCGGCTTCGCCCGAGCTCGCAGCGGAGCAACTCGACATCAACCGGCTTCTGCAAACGCTGCGCCAT
GCGCATGCGCAGCGCTGA

Upstream 100 bases:

>100_bases
CCGGCACGTCGCGTTTGCGCATTTCGTTATCGGCCGCGCACTCGCAGGCGGATCTGGATCGTCTTGAAGCAGGCTTGCAG
CAACTCGGAGCGAAAGCGGC

Downstream 100 bases:

>100_bases
ACCACCATCACATCCATCCATGAGGATCGACGACATGACGCAACTGAACATCGCTCCGGCGTCCACCGACACGGCCGCCG
CCAGCAACAACAACGCCGCA

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MSSTSQNALSLFITGTDTEIGKTFVSAALLRGFVREGLQAAAMKPVAAGAFELDGALHNEDADQLDAASNVLLPPEIRTP
YLLKEPAAPHIAAALENVTLDLGHIVDCHAQALKRAEIVVVEGVGGFRVPLTAAQDTADLAVALELPVVLVVGMRLGCIS
HALLTAEAIAARGLTLAGWVANRIDPDMTFPDENIASIREHLARAYDAPLLGIVPHLNPASPELAAEQLDINRLLQTLRH
AHAQR

Sequences:

>Translated_245_residues
MSSTSQNALSLFITGTDTEIGKTFVSAALLRGFVREGLQAAAMKPVAAGAFELDGALHNEDADQLDAASNVLLPPEIRTP
YLLKEPAAPHIAAALENVTLDLGHIVDCHAQALKRAEIVVVEGVGGFRVPLTAAQDTADLAVALELPVVLVVGMRLGCIS
HALLTAEAIAARGLTLAGWVANRIDPDMTFPDENIASIREHLARAYDAPLLGIVPHLNPASPELAAEQLDINRLLQTLRH
AHAQR
>Mature_244_residues
SSTSQNALSLFITGTDTEIGKTFVSAALLRGFVREGLQAAAMKPVAAGAFELDGALHNEDADQLDAASNVLLPPEIRTPY
LLKEPAAPHIAAALENVTLDLGHIVDCHAQALKRAEIVVVEGVGGFRVPLTAAQDTADLAVALELPVVLVVGMRLGCISH
ALLTAEAIAARGLTLAGWVANRIDPDMTFPDENIASIREHLARAYDAPLLGIVPHLNPASPELAAEQLDINRLLQTLRHA
HAQR

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=222, Percent_Identity=43.2432432432432, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI87081944, Length=207, Percent_Identity=42.0289855072464, Blast_Score=141, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6324385, Length=185, Percent_Identity=34.5945945945946, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 25923; Mature: 25792

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTSQNALSLFITGTDTEIGKTFVSAALLRGFVREGLQAAAMKPVAAGAFELDGALHNE
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCC
DADQLDAASNVLLPPEIRTPYLLKEPAAPHIAAALENVTLDLGHIVDCHAQALKRAEIVV
CHHHHHHCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VEGVGGFRVPLTAAQDTADLAVALELPVVLVVGMRLGCISHALLTAEAIAARGLTLAGWV
EECCCCCEEEEECCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ANRIDPDMTFPDENIASIREHLARAYDAPLLGIVPHLNPASPELAAEQLDINRLLQTLRH
HHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
AHAQR
HHCCC
>Mature Secondary Structure 
SSTSQNALSLFITGTDTEIGKTFVSAALLRGFVREGLQAAAMKPVAAGAFELDGALHNE
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCC
DADQLDAASNVLLPPEIRTPYLLKEPAAPHIAAALENVTLDLGHIVDCHAQALKRAEIVV
CHHHHHHCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VEGVGGFRVPLTAAQDTADLAVALELPVVLVVGMRLGCISHALLTAEAIAARGLTLAGWV
EECCCCCEEEEECCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ANRIDPDMTFPDENIASIREHLARAYDAPLLGIVPHLNPASPELAAEQLDINRLLQTLRH
HHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
AHAQR
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA