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The map label for this gene is mocR [H]

Identifier: 91781543

GI number: 91781543

Start: 184708

End: 186273

Strand: Direct

Name: mocR [H]

Synonym: Bxe_A4302

Alternate gene names: 91781543

Gene position: 184708-186273 (Clockwise)

Preceding gene: 91781539

Following gene: 91781545

Centisome position: 3.77

GC content: 65.9

Gene sequence:

>1566_bases
ATGCTGCGCACGTGGAAGCTGACGTTGCGGCCAGAGCGCAATCGCAGCGAATCGATCCACCTGCAGATCGTCCAGGCGAT
CGTCGAGGACATCCGTCGCGGGCGGCTGGTGTCCGGCACCGCATTGCCGGGCACGCGCGCGCTCGCCGACGACCTGGGCG
TGAATCGCAAGACCGTCGTGCTCGCTTATGACGAGTTGACCGCACAAGGCTGGATCGAAACGGAGGCAAAGCGGGGGAGC
TTCGTCTCGTCGCGGCTGCCGGCGCTGGAATTCAAGCCGGAGGCGACGCACGAACGGCCGTTTCCGGTGGCCTTGTCCGA
CGATGGCGCAAGCCTCTATCACGAGGCCATGTCGCCCGGCGAAGCGAACGGCTCAGGCAATATCGCGTTCACCGACGGCG
TGCCCGACACCCGCCTGATCCCGTTCGATGTACTGTCGCGCGCATTCCGGCACGCGCTCGTGTCGTCGGCGCGCGCGAAC
GCGCTCGGCTACGCTGATCCGCGCGGCACGCCCGAACTGCGAGAGGCGATCGCCGCGATGCTGCGCGCCGAACGTGCGCT
CAACGTCAGCGCCGACAATATCTGCGTCGTGCGCGGCAGCCAGATGGGCATTTTTCTCGCCGCGCGTTTGCTGACGCGCC
CCGGTGACACCATCGCGTTCGAAACGCTCAGCTACCCGCCTGCGCGCGCGGCGTTTCTGTCGTGCGGCGCCGAGCTTGCC
GCGATCGAACTCGACCAGTACGGGCTGGTGCCCGATTCGCTCGAAGCGCTGTGTCGAAAGAAGCCGGTACGCGCCGTGTT
CACCACGCCGCATCATCAGTTTCCGACCACTGTGACGATGCCCGCCGACCGGCGCCTGAGACTGCTCGACCTCGCACGGC
GCTATGGTTTCGTCATCGTCGAGGACGATTACGATCCCGAATTCCATTTCGACTACAAGCCGGTCCTCCCGCTGGCGAGC
ATGAATGCATCGGAGCAGGTATTTTTTATCGGCTCGTTATCGAAAGTGCTCGCGCCGGGACTGCGGCTCGGGTATATCGC
GGCGTCGAAGGAAGCCATTGCGCGCTGTGCCGCGCAGATCATGCTGATCGACCGGCAGGGCAGCGCGCTGACGGAAATGG
CGGTCACGGAACTGATGGCAAGCGGCGAACTGAAACGGCATATCAGGCGCGCGCTGAGAACGTATGAACGGCGGCGGGAC
TTCTGCGCGGAATGCGTGCGGCGCGAACTGGGCGACAAGGTGTCGTTTGCGGTGCCCGGCGGCGGTCTCGCGTTGTGGCT
GACGTTGTCCGGTCAGGTTGCCGCCGGCGAACTGGTGGATCGGGCTGCGCAGGCGGGCATTCGCCTGCTCGCCGGGCGGC
AGTTCTCACCGAACGGCGAGGACGTGCAAGGCGTGCGGCTGGGCTACGGCAATCTCGATGAAACCGAAATGGCCTCCGCG
CTCGCGCGGCTCGGCCGCGCGGCGCGGCGCGATAGTCGCGCTGGTGCAGGGAGTCGGGCGCAAGGGTTCTACTTTCCATT
GCGCCTCGCTCGGCGGTCCATTAGCAAAGCCAGGCAGCTTGCCTGA

Upstream 100 bases:

>100_bases
GCGTCGATGCGACGACGTGGATTCCATCTTAGAAACGTTGTGGACCATAAAAAACATCCAGATTTATAATTTCATCTGGT
CCAGAAAGAAAGGGGGCGCC

Downstream 100 bases:

>100_bases
TCGCGCCGCCCGTACAAGCTCGGCGCCCGATCAGGAAAGAACGTTCAGAACTGATTCCAGCCGTCATCCGCACCGACCGC
TACAGCGGCCGTCGGCCGCG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MLRTWKLTLRPERNRSESIHLQIVQAIVEDIRRGRLVSGTALPGTRALADDLGVNRKTVVLAYDELTAQGWIETEAKRGS
FVSSRLPALEFKPEATHERPFPVALSDDGASLYHEAMSPGEANGSGNIAFTDGVPDTRLIPFDVLSRAFRHALVSSARAN
ALGYADPRGTPELREAIAAMLRAERALNVSADNICVVRGSQMGIFLAARLLTRPGDTIAFETLSYPPARAAFLSCGAELA
AIELDQYGLVPDSLEALCRKKPVRAVFTTPHHQFPTTVTMPADRRLRLLDLARRYGFVIVEDDYDPEFHFDYKPVLPLAS
MNASEQVFFIGSLSKVLAPGLRLGYIAASKEAIARCAAQIMLIDRQGSALTEMAVTELMASGELKRHIRRALRTYERRRD
FCAECVRRELGDKVSFAVPGGGLALWLTLSGQVAAGELVDRAAQAGIRLLAGRQFSPNGEDVQGVRLGYGNLDETEMASA
LARLGRAARRDSRAGAGSRAQGFYFPLRLARRSISKARQLA

Sequences:

>Translated_521_residues
MLRTWKLTLRPERNRSESIHLQIVQAIVEDIRRGRLVSGTALPGTRALADDLGVNRKTVVLAYDELTAQGWIETEAKRGS
FVSSRLPALEFKPEATHERPFPVALSDDGASLYHEAMSPGEANGSGNIAFTDGVPDTRLIPFDVLSRAFRHALVSSARAN
ALGYADPRGTPELREAIAAMLRAERALNVSADNICVVRGSQMGIFLAARLLTRPGDTIAFETLSYPPARAAFLSCGAELA
AIELDQYGLVPDSLEALCRKKPVRAVFTTPHHQFPTTVTMPADRRLRLLDLARRYGFVIVEDDYDPEFHFDYKPVLPLAS
MNASEQVFFIGSLSKVLAPGLRLGYIAASKEAIARCAAQIMLIDRQGSALTEMAVTELMASGELKRHIRRALRTYERRRD
FCAECVRRELGDKVSFAVPGGGLALWLTLSGQVAAGELVDRAAQAGIRLLAGRQFSPNGEDVQGVRLGYGNLDETEMASA
LARLGRAARRDSRAGAGSRAQGFYFPLRLARRSISKARQLA
>Mature_521_residues
MLRTWKLTLRPERNRSESIHLQIVQAIVEDIRRGRLVSGTALPGTRALADDLGVNRKTVVLAYDELTAQGWIETEAKRGS
FVSSRLPALEFKPEATHERPFPVALSDDGASLYHEAMSPGEANGSGNIAFTDGVPDTRLIPFDVLSRAFRHALVSSARAN
ALGYADPRGTPELREAIAAMLRAERALNVSADNICVVRGSQMGIFLAARLLTRPGDTIAFETLSYPPARAAFLSCGAELA
AIELDQYGLVPDSLEALCRKKPVRAVFTTPHHQFPTTVTMPADRRLRLLDLARRYGFVIVEDDYDPEFHFDYKPVLPLAS
MNASEQVFFIGSLSKVLAPGLRLGYIAASKEAIARCAAQIMLIDRQGSALTEMAVTELMASGELKRHIRRALRTYERRRD
FCAECVRRELGDKVSFAVPGGGLALWLTLSGQVAAGELVDRAAQAGIRLLAGRQFSPNGEDVQGVRLGYGNLDETEMASA
LARLGRAARRDSRAGAGSRAQGFYFPLRLARRSISKARQLA

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=354, Percent_Identity=24.8587570621469, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI33469970, Length=354, Percent_Identity=24.8587570621469, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1790797, Length=475, Percent_Identity=27.7894736842105, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1787710, Length=443, Percent_Identity=26.1851015801354, Blast_Score=133, Evalue=3e-32,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 56974; Mature: 56974

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRTWKLTLRPERNRSESIHLQIVQAIVEDIRRGRLVSGTALPGTRALADDLGVNRKTVV
CCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHCCCCEEEE
LAYDELTAQGWIETEAKRGSFVSSRLPALEFKPEATHERPFPVALSDDGASLYHEAMSPG
EEEECCCCCCCEECCCCCCCHHHHCCCCEECCCCCCCCCCCEEEECCCCHHHHHHHCCCC
EANGSGNIAFTDGVPDTRLIPFDVLSRAFRHALVSSARANALGYADPRGTPELREAIAAM
CCCCCCCEEEECCCCCCEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
LRAERALNVSADNICVVRGSQMGIFLAARLLTRPGDTIAFETLSYPPARAAFLSCGAELA
HHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCCEE
AIELDQYGLVPDSLEALCRKKPVRAVFTTPHHQFPTTVTMPADRRLRLLDLARRYGFVIV
EEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCEEECCCCCCHHHHHHHHHCCEEEE
EDDYDPEFHFDYKPVLPLASMNASEQVFFIGSLSKVLAPGLRLGYIAASKEAIARCAAQI
ECCCCCCEECCCCCCCCCCCCCCCCEEEEEECHHHHHCCCCEEEEEHHHHHHHHHHHHHE
MLIDRQGSALTEMAVTELMASGELKRHIRRALRTYERRRDFCAECVRRELGDKVSFAVPG
EEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GGLALWLTLSGQVAAGELVDRAAQAGIRLLAGRQFSPNGEDVQGVRLGYGNLDETEMASA
CCEEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHH
LARLGRAARRDSRAGAGSRAQGFYFPLRLARRSISKARQLA
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLRTWKLTLRPERNRSESIHLQIVQAIVEDIRRGRLVSGTALPGTRALADDLGVNRKTVV
CCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHCCCCEEEE
LAYDELTAQGWIETEAKRGSFVSSRLPALEFKPEATHERPFPVALSDDGASLYHEAMSPG
EEEECCCCCCCEECCCCCCCHHHHCCCCEECCCCCCCCCCCEEEECCCCHHHHHHHCCCC
EANGSGNIAFTDGVPDTRLIPFDVLSRAFRHALVSSARANALGYADPRGTPELREAIAAM
CCCCCCCEEEECCCCCCEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
LRAERALNVSADNICVVRGSQMGIFLAARLLTRPGDTIAFETLSYPPARAAFLSCGAELA
HHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCCEE
AIELDQYGLVPDSLEALCRKKPVRAVFTTPHHQFPTTVTMPADRRLRLLDLARRYGFVIV
EEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCEEECCCCCCHHHHHHHHHCCEEEE
EDDYDPEFHFDYKPVLPLASMNASEQVFFIGSLSKVLAPGLRLGYIAASKEAIARCAAQI
ECCCCCCEECCCCCCCCCCCCCCCCEEEEEECHHHHHCCCCEEEEEHHHHHHHHHHHHHE
MLIDRQGSALTEMAVTELMASGELKRHIRRALRTYERRRDFCAECVRRELGDKVSFAVPG
EEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GGLALWLTLSGQVAAGELVDRAAQAGIRLLAGRQFSPNGEDVQGVRLGYGNLDETEMASA
CCEEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHH
LARLGRAARRDSRAGAGSRAQGFYFPLRLARRSISKARQLA
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]