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The map label for this gene is lon [H]

Identifier: 91781511

GI number: 91781511

Start: 152417

End: 153394

Strand: Direct

Name: lon [H]

Synonym: Bxe_A4335

Alternate gene names: 91781511

Gene position: 152417-153394 (Clockwise)

Preceding gene: 91781508

Following gene: 91781512

Centisome position: 3.11

GC content: 61.35

Gene sequence:

>978_bases
ATGACAACAGCAATGGTCAAACAGGAAATCGCCGTGGCGTCTTTCAGTCGGGTGTACGACCTCGATCAGGTCGAAACCGC
GCTGAACGATCTCGGTGAAGGCGCGAACGAGGCACTGCGCGCGACATACGAAAAGATGCTGAAAACCGGCAATCTGCGCT
TTTGCGTGAAGCCGAACCGCATGCCGTCGATCGACGATCTGATCGACGCGCTGCCCAATTTTTCAGCACCGCTCGACGAC
ATCCGCAAACAGGTCGCCTTGTGTCTCGAAACCGAAGACCGCCTGGAACTGATGCCGATTCTGCTGCTCGGCGACCCCGG
CATCGGCAAGACTCACTTTGCCAGGCAGTTGGCGCGCCTGCTCGGCACCGCCTATCAATACGTGGCGATGAGTTCGCTGA
CGGCGGGGTGGATTCTGTCGGGCGCCTCGTCGCAATGGAAGAACGCGAAGCCGGGCAAGGTGTTCGATGCGCTGGTGAAT
GGCAGCTACGCGAATCCGGTGATTGCCGTCGATGAAATCGACAAGGCGACCGGCGACTCGCAATACGATCCGCTCGGCGC
GTTGTATGCGCTGCTCGAGCACGATACGGCGCAGACGTTCATCGACGAATTCGCCGAGATTCCGATCAATGCCGGGCATG
TGATCTGGATTGCAACGGCGAACGATGAGCGCTCGATTCCCGAGCCGATCCTGAACCGGATGAACGTGTACGAAATCCCT
GCGCCGGACCGCGACGGCGCGCGCCGCATTGCCCAGGCGATCTACGACGGGATCCGCTCGGCGCATAACTGGGGACTGCG
CTTTCCCGAGGTGCTCGGCGACGCTGCGCTCGATGCGCTGATGCGGGCGTCGCCGCGTGAAATGCGGCGGGCGATTCTGA
ACGGCTTCGGCGCGGCGCGCATCGACGGGCGCGACCGGATCGAAGCCGGCGACATTCACCTCGATTTCGGAAATCGGCGA
AAACCCATCGGGTTTTGA

Upstream 100 bases:

>100_bases
ACGACTGCTGGCTTGCACGCGAATATGTCCTCGCTACACTGGACCTGAAACGGCGCCCATCAGGTGCCGCAGCAGCAGGA
CCAGCCAGACGGGGTGAGCG

Downstream 100 bases:

>100_bases
CTATTTTTTGGCACTTTTTCGTAAAAAACCGCCTCCTGGTGGGCTTTTCCATAGCCAAACCGGGAATCGGTACCGCAAAT
GGTGTGAATGCTGCGGCAAT

Product: putative ATP-dependent protease La

Products: NA

Alternate protein names: ATP-dependent protease La [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MTTAMVKQEIAVASFSRVYDLDQVETALNDLGEGANEALRATYEKMLKTGNLRFCVKPNRMPSIDDLIDALPNFSAPLDD
IRKQVALCLETEDRLELMPILLLGDPGIGKTHFARQLARLLGTAYQYVAMSSLTAGWILSGASSQWKNAKPGKVFDALVN
GSYANPVIAVDEIDKATGDSQYDPLGALYALLEHDTAQTFIDEFAEIPINAGHVIWIATANDERSIPEPILNRMNVYEIP
APDRDGARRIAQAIYDGIRSAHNWGLRFPEVLGDAALDALMRASPREMRRAILNGFGAARIDGRDRIEAGDIHLDFGNRR
KPIGF

Sequences:

>Translated_325_residues
MTTAMVKQEIAVASFSRVYDLDQVETALNDLGEGANEALRATYEKMLKTGNLRFCVKPNRMPSIDDLIDALPNFSAPLDD
IRKQVALCLETEDRLELMPILLLGDPGIGKTHFARQLARLLGTAYQYVAMSSLTAGWILSGASSQWKNAKPGKVFDALVN
GSYANPVIAVDEIDKATGDSQYDPLGALYALLEHDTAQTFIDEFAEIPINAGHVIWIATANDERSIPEPILNRMNVYEIP
APDRDGARRIAQAIYDGIRSAHNWGLRFPEVLGDAALDALMRASPREMRRAILNGFGAARIDGRDRIEAGDIHLDFGNRR
KPIGF
>Mature_324_residues
TTAMVKQEIAVASFSRVYDLDQVETALNDLGEGANEALRATYEKMLKTGNLRFCVKPNRMPSIDDLIDALPNFSAPLDDI
RKQVALCLETEDRLELMPILLLGDPGIGKTHFARQLARLLGTAYQYVAMSSLTAGWILSGASSQWKNAKPGKVFDALVNG
SYANPVIAVDEIDKATGDSQYDPLGALYALLEHDTAQTFIDEFAEIPINAGHVIWIATANDERSIPEPILNRMNVYEIPA
PDRDGARRIAQAIYDGIRSAHNWGLRFPEVLGDAALDALMRASPREMRRAILNGFGAARIDGRDRIEAGDIHLDFGNRRK
PIGF

Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced

COG id: COG0466

COG function: function code O; ATP-dependent Lon protease, bacterial type

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Lon domain [H]

Homologues:

Organism=Homo sapiens, GI21396489, Length=140, Percent_Identity=33.5714285714286, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI31377667, Length=155, Percent_Identity=30.3225806451613, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI1786643, Length=155, Percent_Identity=30.9677419354839, Blast_Score=84, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17556486, Length=166, Percent_Identity=30.1204819277108, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17505831, Length=137, Percent_Identity=31.3868613138686, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319449, Length=190, Percent_Identity=32.1052631578947, Blast_Score=96, Evalue=6e-21,
Organism=Drosophila melanogaster, GI221513036, Length=185, Percent_Identity=30.8108108108108, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24666867, Length=185, Percent_Identity=30.8108108108108, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008269
- InterPro:   IPR004815
- InterPro:   IPR003111
- InterPro:   IPR008268
- InterPro:   IPR001984
- InterPro:   IPR015947
- InterPro:   IPR020568 [H]

Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]

EC number: =3.4.21.53 [H]

Molecular weight: Translated: 35797; Mature: 35666

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00285 POTATO_INHIBITOR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAMVKQEIAVASFSRVYDLDQVETALNDLGEGANEALRATYEKMLKTGNLRFCVKPNR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCC
MPSIDDLIDALPNFSAPLDDIRKQVALCLETEDRLELMPILLLGDPGIGKTHFARQLARL
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHEEEEEECCCCCCHHHHHHHHHHH
LGTAYQYVAMSSLTAGWILSGASSQWKNAKPGKVFDALVNGSYANPVIAVDEIDKATGDS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCHHHCCCC
QYDPLGALYALLEHDTAQTFIDEFAEIPINAGHVIWIATANDERSIPEPILNRMNVYEIP
CCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHCCCCEEECC
APDRDGARRIAQAIYDGIRSAHNWGLRFPEVLGDAALDALMRASPREMRRAILNGFGAAR
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEE
IDGRDRIEAGDIHLDFGNRRKPIGF
ECCCCCCEECCEEECCCCCCCCCCC
>Mature Secondary Structure 
TTAMVKQEIAVASFSRVYDLDQVETALNDLGEGANEALRATYEKMLKTGNLRFCVKPNR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCC
MPSIDDLIDALPNFSAPLDDIRKQVALCLETEDRLELMPILLLGDPGIGKTHFARQLARL
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHEEEEEECCCCCCHHHHHHHHHHH
LGTAYQYVAMSSLTAGWILSGASSQWKNAKPGKVFDALVNGSYANPVIAVDEIDKATGDS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCHHHCCCC
QYDPLGALYALLEHDTAQTFIDEFAEIPINAGHVIWIATANDERSIPEPILNRMNVYEIP
CCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHCCCCEEECC
APDRDGARRIAQAIYDGIRSAHNWGLRFPEVLGDAALDALMRASPREMRRAILNGFGAAR
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEE
IDGRDRIEAGDIHLDFGNRRKPIGF
ECCCCCCEECCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA