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The map label for this gene is coxL1 [H]

Identifier: 91781494

GI number: 91781494

Start: 131417

End: 133798

Strand: Reverse

Name: coxL1 [H]

Synonym: Bxe_A4352

Alternate gene names: 91781494

Gene position: 133798-131417 (Counterclockwise)

Preceding gene: 91781495

Following gene: 91781493

Centisome position: 2.73

GC content: 65.07

Gene sequence:

>2382_bases
ATGAACGCACCCGAAACTCACCTGATCGGCGCCTCCGTCGAACGTAAGGAAGACTATCGTTTCCTGACCGGCAACGGCCA
GTACACCGACGACATCGTCCTGCCCCAGCAAACCTACGCGGTATTCCTGCGCTCGCCGTACGCGCACGCGAAGATCAACA
CCATCGACACCACCGCGGCCAAACAGTCGCCCGGCGTGGTGGCGATCTTCACCGGCGCGGACATGGCCGCTGACAACGTC
GGCGGCCTGCCGTGCGGCTGGCTGATCCACAGCACCGACGGCAAGCCGATGAACGAGCCGCCGCATCCGGTCATCGCGCA
TACGAAAGTGCGCCACGTCGGCGACCAGGTCGCGCTCGTCATCGCCGATTCGATCAAGGCCGCCAAAGACGCCGCCGAAC
TGATCGAAGTCGACTACGACGTGCTGCCGGCGGTAGTCGACACCGCGCATGCAGCCGACGCCGGCCAGCCCGCCGTTCAC
GACGAAGTGCCCGACAACGTCTGCTACAACTGGGGCCACGGCGACAAAGCCGCCACCGACGCCGCCTTCGCCAAAGCCGC
GCACGTCACCACGCTCGACATCGTCAACAACCGGCTGATTCCGAACGCGATCGAACCGCGCGCGGTCAACGCGAGCTATT
CGGCGCAGGACGACAGCTACACGCTCTACGTCGCGAACCAGAATCCGCATGTGGAGCGCCTGCTGATGGCCGCCTTCGTG
CTGTCGCTGCCGGAATCGAAACTGCGCGTGATCGCGCCGGACGTGGGCGGCGGCTTCGGATCGAAGATCTTCCTGTACGC
CGAAGACGTCGCGCTGACCTGGGCGTCGAAGAAAATCCGCCGTCCGGTGAAGTGGACGGCCGAGCGCTCGGAAGCGTTCG
TCTCCGACGCGCACGGCCGCGATCACGTGACCAAAGCCGAACTGGCACTGGACGCGGACGGCAGGTTCCTCGCCATGCGC
ATCCATACAACAGCCAACATGGGCGCGTATCTGTCCACCTTCGCCTCCAGCGTGCCGACCATTCTGTACGCCACGCTGCT
CGCCGGCCAGTACGCCACGCCCGCGATCTACGCGGAAGTGAAAGCGGTCTTCACCAACACCGTTCCCGTCGACGCCTATC
GCGGCGCGGGCCGCCCCGAAGCGACGTATGTCGTGGAGCGCCTCGTCGAAACGGCCGCGCGCGAACTGAAGCTCGATCCG
GCCGAGATCCGCCGCCGCAATTTCATTCGCGAGTTTCCGTACGCGACGCCGGTCGGCCTCACCTACGACACCGGCGACTA
CGAGACGATCCTCGCGCGTTCGCTCGAACTCGCGGACGTCAAAGGCTTCGCAGCGCGCAGACAGGAATCCGAAAAGAACG
GCAAGCTGCGCGGCCTCGGCTATTCGTGCTACATCGAAGCCTGCGGTCTCGCGCCTTCGAATATCGCGGGCGCGTTGGGC
GCGCGGGCCGGCCTGTTCGAAGTCGGTCAGATTCGCGTGCATCCCACCGGATCGGTCACCGTGTTCACGGGCTCGCACAG
TCACGGCCAGGGACATGAGACAACCTTCGCGCAAGTGGTGGCCGAGCGGCTCGGCATTGCGCTGGAAAGCGTCGAGATCG
TCCACGGCGACACCGGCCGCATTCCGTTCGGCATGGGCACGTATGGCTCGCGTTCCATCGCGGTCGGCGGCTCGGCGATC
ATGAAAGCGCTCGACAAGATCGAAACCAAGGCGAAGAAGATCGCCGCGCACCTGCTCGAAGCCGCTGCGGAAGACATCGA
GTTCAAGGACGGCGTATTCCGCGTCGCGGGCACCGATCGCACCAAGGCGTTTGCCGAGATTTCGCTCGCCGCGTACGTGC
CGCACAACTATCCGCTCGACGTGCTCGAACCCGGCCTCGAAGAAAGCGCGTTCTACGATCCGACCAACTTCACCTATCCA
TCCGGCGCGTACATCTGCGAGATCGAAGTCGACCCGGACACGGGCGTGTGCCGGATCCAGCAGTTCACCGCGGTCGACGA
TTTCGGCAACGTGATCAACCCGATGATCGTCGAAGGCCAGGTGCATGGCGGGCTCGCTCAGGGCATCGGCCAGGCGATGC
TGGAGCGCTGCGTATACGACAACGAGAGCGGCCAGTTGCTGTCCGGCTCGTACATGGATTACGCGATGCCGCATGCGTCC
GATCTGCCGGACTTCACCGTCGAAACCGCGAAGGGCACGCCGTGCACGCACAATCCGCTCGGCGTGAAAGGCTGCGGCGA
AGCGGGCGCGATCGGCTCGCCGCCGGCGGTGATCAACGCGATCCTCGACGCGCTCGCGCCGCTCGGCGTGACCGACCTGC
AAATGCCGGCCACGCCGCATCGCGTGTGGTCCGCGATTCACGCTGCCAAACAAGCCCATTGA

Upstream 100 bases:

>100_bases
CTCGAAGGCGCCGAAGGCATGAAGTCCACCGGCACGGCCAACGCCGCCGCGAATGCCACCGCGCAGGCCAACGCACCGGC
CACCGCCTGAGGAGCCGACG

Downstream 100 bases:

>100_bases
GATCCTGAGCGGAGCATTCGACATGTATTCATTCGAGTATCAACGCGCGACGGATCCGAAAGCGGCCGCCGCCAGCCTCA
CCGCCGACAGCGACGCGAAG

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 793; Mature: 793

Protein sequence:

>793_residues
MNAPETHLIGASVERKEDYRFLTGNGQYTDDIVLPQQTYAVFLRSPYAHAKINTIDTTAAKQSPGVVAIFTGADMAADNV
GGLPCGWLIHSTDGKPMNEPPHPVIAHTKVRHVGDQVALVIADSIKAAKDAAELIEVDYDVLPAVVDTAHAADAGQPAVH
DEVPDNVCYNWGHGDKAATDAAFAKAAHVTTLDIVNNRLIPNAIEPRAVNASYSAQDDSYTLYVANQNPHVERLLMAAFV
LSLPESKLRVIAPDVGGGFGSKIFLYAEDVALTWASKKIRRPVKWTAERSEAFVSDAHGRDHVTKAELALDADGRFLAMR
IHTTANMGAYLSTFASSVPTILYATLLAGQYATPAIYAEVKAVFTNTVPVDAYRGAGRPEATYVVERLVETAARELKLDP
AEIRRRNFIREFPYATPVGLTYDTGDYETILARSLELADVKGFAARRQESEKNGKLRGLGYSCYIEACGLAPSNIAGALG
ARAGLFEVGQIRVHPTGSVTVFTGSHSHGQGHETTFAQVVAERLGIALESVEIVHGDTGRIPFGMGTYGSRSIAVGGSAI
MKALDKIETKAKKIAAHLLEAAAEDIEFKDGVFRVAGTDRTKAFAEISLAAYVPHNYPLDVLEPGLEESAFYDPTNFTYP
SGAYICEIEVDPDTGVCRIQQFTAVDDFGNVINPMIVEGQVHGGLAQGIGQAMLERCVYDNESGQLLSGSYMDYAMPHAS
DLPDFTVETAKGTPCTHNPLGVKGCGEAGAIGSPPAVINAILDALAPLGVTDLQMPATPHRVWSAIHAAKQAH

Sequences:

>Translated_793_residues
MNAPETHLIGASVERKEDYRFLTGNGQYTDDIVLPQQTYAVFLRSPYAHAKINTIDTTAAKQSPGVVAIFTGADMAADNV
GGLPCGWLIHSTDGKPMNEPPHPVIAHTKVRHVGDQVALVIADSIKAAKDAAELIEVDYDVLPAVVDTAHAADAGQPAVH
DEVPDNVCYNWGHGDKAATDAAFAKAAHVTTLDIVNNRLIPNAIEPRAVNASYSAQDDSYTLYVANQNPHVERLLMAAFV
LSLPESKLRVIAPDVGGGFGSKIFLYAEDVALTWASKKIRRPVKWTAERSEAFVSDAHGRDHVTKAELALDADGRFLAMR
IHTTANMGAYLSTFASSVPTILYATLLAGQYATPAIYAEVKAVFTNTVPVDAYRGAGRPEATYVVERLVETAARELKLDP
AEIRRRNFIREFPYATPVGLTYDTGDYETILARSLELADVKGFAARRQESEKNGKLRGLGYSCYIEACGLAPSNIAGALG
ARAGLFEVGQIRVHPTGSVTVFTGSHSHGQGHETTFAQVVAERLGIALESVEIVHGDTGRIPFGMGTYGSRSIAVGGSAI
MKALDKIETKAKKIAAHLLEAAAEDIEFKDGVFRVAGTDRTKAFAEISLAAYVPHNYPLDVLEPGLEESAFYDPTNFTYP
SGAYICEIEVDPDTGVCRIQQFTAVDDFGNVINPMIVEGQVHGGLAQGIGQAMLERCVYDNESGQLLSGSYMDYAMPHAS
DLPDFTVETAKGTPCTHNPLGVKGCGEAGAIGSPPAVINAILDALAPLGVTDLQMPATPHRVWSAIHAAKQAH
>Mature_793_residues
MNAPETHLIGASVERKEDYRFLTGNGQYTDDIVLPQQTYAVFLRSPYAHAKINTIDTTAAKQSPGVVAIFTGADMAADNV
GGLPCGWLIHSTDGKPMNEPPHPVIAHTKVRHVGDQVALVIADSIKAAKDAAELIEVDYDVLPAVVDTAHAADAGQPAVH
DEVPDNVCYNWGHGDKAATDAAFAKAAHVTTLDIVNNRLIPNAIEPRAVNASYSAQDDSYTLYVANQNPHVERLLMAAFV
LSLPESKLRVIAPDVGGGFGSKIFLYAEDVALTWASKKIRRPVKWTAERSEAFVSDAHGRDHVTKAELALDADGRFLAMR
IHTTANMGAYLSTFASSVPTILYATLLAGQYATPAIYAEVKAVFTNTVPVDAYRGAGRPEATYVVERLVETAARELKLDP
AEIRRRNFIREFPYATPVGLTYDTGDYETILARSLELADVKGFAARRQESEKNGKLRGLGYSCYIEACGLAPSNIAGALG
ARAGLFEVGQIRVHPTGSVTVFTGSHSHGQGHETTFAQVVAERLGIALESVEIVHGDTGRIPFGMGTYGSRSIAVGGSAI
MKALDKIETKAKKIAAHLLEAAAEDIEFKDGVFRVAGTDRTKAFAEISLAAYVPHNYPLDVLEPGLEESAFYDPTNFTYP
SGAYICEIEVDPDTGVCRIQQFTAVDDFGNVINPMIVEGQVHGGLAQGIGQAMLERCVYDNESGQLLSGSYMDYAMPHAS
DLPDFTVETAKGTPCTHNPLGVKGCGEAGAIGSPPAVINAILDALAPLGVTDLQMPATPHRVWSAIHAAKQAH

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=795, Percent_Identity=25.2830188679245, Blast_Score=146, Evalue=7e-35,
Organism=Homo sapiens, GI91823271, Length=798, Percent_Identity=25.187969924812, Blast_Score=139, Evalue=9e-33,
Organism=Escherichia coli, GI1789230, Length=788, Percent_Identity=29.0609137055838, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI1789246, Length=832, Percent_Identity=26.9230769230769, Blast_Score=214, Evalue=2e-56,
Organism=Escherichia coli, GI1786478, Length=737, Percent_Identity=24.2876526458616, Blast_Score=140, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17540638, Length=830, Percent_Identity=24.4578313253012, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17539860, Length=770, Percent_Identity=24.6753246753247, Blast_Score=151, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI32566215, Length=768, Percent_Identity=23.5677083333333, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17737937, Length=760, Percent_Identity=25.9210526315789, Blast_Score=139, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24647193, Length=819, Percent_Identity=22.2222222222222, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24647197, Length=565, Percent_Identity=24.9557522123894, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24647195, Length=565, Percent_Identity=24.9557522123894, Blast_Score=95, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 84879; Mature: 84879

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPETHLIGASVERKEDYRFLTGNGQYTDDIVLPQQTYAVFLRSPYAHAKINTIDTTAA
CCCCCCEEECCCCCCCCCCEEEECCCCCCCCEECCCHHEEEEEECCCCCEEEEEEECCCC
KQSPGVVAIFTGADMAADNVGGLPCGWLIHSTDGKPMNEPPHPVIAHTKVRHVGDQVALV
CCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEECHHHHHCCCEEEEE
IADSIKAAKDAAELIEVDYDVLPAVVDTAHAADAGQPAVHDEVPDNVCYNWGHGDKAATD
EEHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCHHHH
AAFAKAAHVTTLDIVNNRLIPNAIEPRAVNASYSAQDDSYTLYVANQNPHVERLLMAAFV
HHHHHHHHEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
LSLPESKLRVIAPDVGGGFGSKIFLYAEDVALTWASKKIRRPVKWTAERSEAFVSDAHGR
HHCCCCCEEEEECCCCCCCCCEEEEEEECEEEEEHHHHHCCCCCCHHHHHHHHHHCCCCC
DHVTKAELALDADGRFLAMRIHTTANMGAYLSTFASSVPTILYATLLAGQYATPAIYAEV
CCCEEEHEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
KAVFTNTVPVDAYRGAGRPEATYVVERLVETAARELKLDPAEIRRRNFIREFPYATPVGL
HHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCE
TYDTGDYETILARSLELADVKGFAARRQESEKNGKLRGLGYSCYIEACGLAPSNIAGALG
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCHHHHHHHH
ARAGLFEVGQIRVHPTGSVTVFTGSHSHGQGHETTFAQVVAERLGIALESVEIVHGDTGR
CCCCCEEECEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCEEEEEEEEECCCCC
IPFGMGTYGSRSIAVGGSAIMKALDKIETKAKKIAAHLLEAAAEDIEFKDGVFRVAGTDR
CCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
TKAFAEISLAAYVPHNYPLDVLEPGLEESAFYDPTNFTYPSGAYICEIEVDPDTGVCRIQ
HHHHHEEEEEEECCCCCCHHHHCCCCCCCCEECCCCCCCCCCCEEEEEEECCCCCEEEEE
QFTAVDDFGNVINPMIVEGQVHGGLAQGIGQAMLERCVYDNESGQLLSGSYMDYAMPHAS
EEHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHCCCCCC
DLPDFTVETAKGTPCTHNPLGVKGCGEAGAIGSPPAVINAILDALAPLGVTDLQMPATPH
CCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHH
RVWSAIHAAKQAH
HHHHHHHHHHHCC
>Mature Secondary Structure
MNAPETHLIGASVERKEDYRFLTGNGQYTDDIVLPQQTYAVFLRSPYAHAKINTIDTTAA
CCCCCCEEECCCCCCCCCCEEEECCCCCCCCEECCCHHEEEEEECCCCCEEEEEEECCCC
KQSPGVVAIFTGADMAADNVGGLPCGWLIHSTDGKPMNEPPHPVIAHTKVRHVGDQVALV
CCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEECHHHHHCCCEEEEE
IADSIKAAKDAAELIEVDYDVLPAVVDTAHAADAGQPAVHDEVPDNVCYNWGHGDKAATD
EEHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCHHHH
AAFAKAAHVTTLDIVNNRLIPNAIEPRAVNASYSAQDDSYTLYVANQNPHVERLLMAAFV
HHHHHHHHEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
LSLPESKLRVIAPDVGGGFGSKIFLYAEDVALTWASKKIRRPVKWTAERSEAFVSDAHGR
HHCCCCCEEEEECCCCCCCCCEEEEEEECEEEEEHHHHHCCCCCCHHHHHHHHHHCCCCC
DHVTKAELALDADGRFLAMRIHTTANMGAYLSTFASSVPTILYATLLAGQYATPAIYAEV
CCCEEEHEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
KAVFTNTVPVDAYRGAGRPEATYVVERLVETAARELKLDPAEIRRRNFIREFPYATPVGL
HHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCE
TYDTGDYETILARSLELADVKGFAARRQESEKNGKLRGLGYSCYIEACGLAPSNIAGALG
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCHHHHHHHH
ARAGLFEVGQIRVHPTGSVTVFTGSHSHGQGHETTFAQVVAERLGIALESVEIVHGDTGR
CCCCCEEECEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCEEEEEEEEECCCCC
IPFGMGTYGSRSIAVGGSAIMKALDKIETKAKKIAAHLLEAAAEDIEFKDGVFRVAGTDR
CCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
TKAFAEISLAAYVPHNYPLDVLEPGLEESAFYDPTNFTYPSGAYICEIEVDPDTGVCRIQ
HHHHHEEEEEEECCCCCCHHHHCCCCCCCCEECCCCCCCCCCCEEEEEEECCCCCEEEEE
QFTAVDDFGNVINPMIVEGQVHGGLAQGIGQAMLERCVYDNESGQLLSGSYMDYAMPHAS
EEHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHCCCCCC
DLPDFTVETAKGTPCTHNPLGVKGCGEAGAIGSPPAVINAILDALAPLGVTDLQMPATPH
CCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHH
RVWSAIHAAKQAH
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]