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The map label for this gene is ybdL [H]

Identifier: 91781412

GI number: 91781412

Start: 34841

End: 35995

Strand: Direct

Name: ybdL [H]

Synonym: Bxe_A4435

Alternate gene names: 91781412

Gene position: 34841-35995 (Clockwise)

Preceding gene: 91781411

Following gene: 91781413

Centisome position: 0.71

GC content: 60.87

Gene sequence:

>1155_bases
ATGCAGAGCGCCATGCAAGCCCGCTCGAAGTTGCCTGATGTGGGCACGACGATTTTTACCGTGATCGGTCAACTGGCCGC
GCAATACGATGCGCTGAACCTGTCGCAAGGCGCACCGAATTTCGCGCCGGACGCCAGCCTGATCGACGGCGTTGCTCAGG
CCATGCGCGCTGGTCATAACCAGTACGCGCCGATGGCCGGCATCGCCGCTCTGCGCGAAGCGCTCGCCGACAAGGTCGCC
ACGCTGTACGGCGTGCACTACGACCCGGCCAGCGAAGTAACCGTGATCGCCAGCGCGAGCGAAGGGCTGTATTCGACCAT
CAGCGCATTGGTGCATCCGGGCGATGAAGTGATCTACTTCGAGCCTTCGTTCGACAGCTATGGCCCGATCGTCCGCCTGC
AAGGCGCCACGCCCGTGGCGATCAAACTGTCCCTGAACGATTTCCGGGTGGACTGGGACGAGGTCGCCGCCGCGATCACG
CCAAAGACCCGCATGATCATCATCAACACGCCGCACAATCCGACCGCGACCGTGTTCAGCGAAGCCGACGTCGCGCGCCT
GAAGGCCATTACGCGCAATACCGATATCGTGATTCTCGCCGACGAGGTCTACGAACACGTGGTGTTCGACGGCGCGAAGC
ATCAAAGCATGGCCTGCCATGCCGAACTCGCGGAGCGCAGCGTGATCGTTTCGTCGTTCGGCAAGTCGTATCACGTGACC
GGATGGCGCGTCGGCTACTGCCTCGCACCCGCTGCGTTGATGGACGAGATTCGCAAAGTCCATCAGTTCATGGTGTTTTC
TGCCGATACACCAATGCAGTACGCGTTTGTCGACGCATTGGCCAGGCGCGAAAGCTACCTCGGCTTGTCCGCGTTCTATC
AGAAGAAGCGCGATCTGCTCACGGACGCACTGCGCGATTCGCGCTTCGAGCTGCTGCCAAGCGAGGGCAGCTTCTTCATG
CTCGCGCGTTTTCGCGGCTTCTCCGAGGAAAGCGATAGCGATTTCGTGCTGCGCCTGATTCGCGATGCGCGCGTCGCGAC
GATTCCTCTTTCAGCGTTCTATACCGACGGCACGGATTCCGGCTTGATCCGCCTGAGCTTTTCGAAGGATGATGCGACCT
TGATCGAAGGCGCGCGCCGTTTGTGCCAAATCTGA

Upstream 100 bases:

>100_bases
ACGGTTCTTTGGCTGATGCCTAATCACCAAACCAGAAGGGACCGCCGCGCAGCAGGCCGTCCGTGAATTCGCTGCCGGAT
GGAGAAAGGGAGAAAGCCTT

Downstream 100 bases:

>100_bases
TCGGGGCAGTGACGGCCCTGCGCGATGGCTCTATTTTTGACCGCAGTATGATCGTCGCGCCGTCACGCATCAGCGCGCCG
CAACACGGCGTGACAATAAA

Product: putative aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MQSAMQARSKLPDVGTTIFTVIGQLAAQYDALNLSQGAPNFAPDASLIDGVAQAMRAGHNQYAPMAGIAALREALADKVA
TLYGVHYDPASEVTVIASASEGLYSTISALVHPGDEVIYFEPSFDSYGPIVRLQGATPVAIKLSLNDFRVDWDEVAAAIT
PKTRMIIINTPHNPTATVFSEADVARLKAITRNTDIVILADEVYEHVVFDGAKHQSMACHAELAERSVIVSSFGKSYHVT
GWRVGYCLAPAALMDEIRKVHQFMVFSADTPMQYAFVDALARRESYLGLSAFYQKKRDLLTDALRDSRFELLPSEGSFFM
LARFRGFSEESDSDFVLRLIRDARVATIPLSAFYTDGTDSGLIRLSFSKDDATLIEGARRLCQI

Sequences:

>Translated_384_residues
MQSAMQARSKLPDVGTTIFTVIGQLAAQYDALNLSQGAPNFAPDASLIDGVAQAMRAGHNQYAPMAGIAALREALADKVA
TLYGVHYDPASEVTVIASASEGLYSTISALVHPGDEVIYFEPSFDSYGPIVRLQGATPVAIKLSLNDFRVDWDEVAAAIT
PKTRMIIINTPHNPTATVFSEADVARLKAITRNTDIVILADEVYEHVVFDGAKHQSMACHAELAERSVIVSSFGKSYHVT
GWRVGYCLAPAALMDEIRKVHQFMVFSADTPMQYAFVDALARRESYLGLSAFYQKKRDLLTDALRDSRFELLPSEGSFFM
LARFRGFSEESDSDFVLRLIRDARVATIPLSAFYTDGTDSGLIRLSFSKDDATLIEGARRLCQI
>Mature_384_residues
MQSAMQARSKLPDVGTTIFTVIGQLAAQYDALNLSQGAPNFAPDASLIDGVAQAMRAGHNQYAPMAGIAALREALADKVA
TLYGVHYDPASEVTVIASASEGLYSTISALVHPGDEVIYFEPSFDSYGPIVRLQGATPVAIKLSLNDFRVDWDEVAAAIT
PKTRMIIINTPHNPTATVFSEADVARLKAITRNTDIVILADEVYEHVVFDGAKHQSMACHAELAERSVIVSSFGKSYHVT
GWRVGYCLAPAALMDEIRKVHQFMVFSADTPMQYAFVDALARRESYLGLSAFYQKKRDLLTDALRDSRFELLPSEGSFFM
LARFRGFSEESDSDFVLRLIRDARVATIPLSAFYTDGTDSGLIRLSFSKDDATLIEGARRLCQI

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=409, Percent_Identity=30.3178484107579, Blast_Score=201, Evalue=6e-52,
Organism=Homo sapiens, GI169881279, Length=409, Percent_Identity=30.3178484107579, Blast_Score=201, Evalue=6e-52,
Organism=Homo sapiens, GI56713254, Length=396, Percent_Identity=30.050505050505, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI56713256, Length=390, Percent_Identity=30.5128205128205, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI169881281, Length=408, Percent_Identity=26.4705882352941, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI4507369, Length=380, Percent_Identity=25.7894736842105, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1786816, Length=378, Percent_Identity=49.4708994708995, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI1788722, Length=360, Percent_Identity=25, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788627, Length=344, Percent_Identity=26.453488372093, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787710, Length=222, Percent_Identity=27.9279279279279, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=396, Percent_Identity=33.0808080808081, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI71994476, Length=396, Percent_Identity=33.0808080808081, Blast_Score=211, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI17567369, Length=409, Percent_Identity=30.3178484107579, Blast_Score=198, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17567663, Length=309, Percent_Identity=24.5954692556634, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=384, Percent_Identity=30.2083333333333, Blast_Score=167, Evalue=2e-42,
Organism=Drosophila melanogaster, GI28573069, Length=395, Percent_Identity=33.9240506329114, Blast_Score=204, Evalue=7e-53,
Organism=Drosophila melanogaster, GI24646114, Length=395, Percent_Identity=33.9240506329114, Blast_Score=204, Evalue=7e-53,
Organism=Drosophila melanogaster, GI28573067, Length=395, Percent_Identity=33.9240506329114, Blast_Score=204, Evalue=7e-53,
Organism=Drosophila melanogaster, GI28573065, Length=395, Percent_Identity=33.9240506329114, Blast_Score=204, Evalue=7e-53,
Organism=Drosophila melanogaster, GI18859735, Length=377, Percent_Identity=26.2599469496021, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42069; Mature: 42069

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSAMQARSKLPDVGTTIFTVIGQLAAQYDALNLSQGAPNFAPDASLIDGVAQAMRAGHN
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
QYAPMAGIAALREALADKVATLYGVHYDPASEVTVIASASEGLYSTISALVHPGDEVIYF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEE
EPSFDSYGPIVRLQGATPVAIKLSLNDFRVDWDEVAAAITPKTRMIIINTPHNPTATVFS
CCCCCCCCCEEEECCCCCEEEEEECCCCCCCHHHHHHHCCCCEEEEEEECCCCCCEEEEC
EADVARLKAITRNTDIVILADEVYEHVVFDGAKHQSMACHAELAERSVIVSSFGKSYHVT
CHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECC
GWRVGYCLAPAALMDEIRKVHQFMVFSADTPMQYAFVDALARRESYLGLSAFYQKKRDLL
CEEHHHHHCHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TDALRDSRFELLPSEGSFFMLARFRGFSEESDSDFVLRLIRDARVATIPLSAFYTDGTDS
HHHHHCCCEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEEEEECCCCCC
GLIRLSFSKDDATLIEGARRLCQI
CEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MQSAMQARSKLPDVGTTIFTVIGQLAAQYDALNLSQGAPNFAPDASLIDGVAQAMRAGHN
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
QYAPMAGIAALREALADKVATLYGVHYDPASEVTVIASASEGLYSTISALVHPGDEVIYF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEE
EPSFDSYGPIVRLQGATPVAIKLSLNDFRVDWDEVAAAITPKTRMIIINTPHNPTATVFS
CCCCCCCCCEEEECCCCCEEEEEECCCCCCCHHHHHHHCCCCEEEEEEECCCCCCEEEEC
EADVARLKAITRNTDIVILADEVYEHVVFDGAKHQSMACHAELAERSVIVSSFGKSYHVT
CHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECC
GWRVGYCLAPAALMDEIRKVHQFMVFSADTPMQYAFVDALARRESYLGLSAFYQKKRDLL
CEEHHHHHCHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TDALRDSRFELLPSEGSFFMLARFRGFSEESDSDFVLRLIRDARVATIPLSAFYTDGTDS
HHHHHCCCEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEEEEECCCCCC
GLIRLSFSKDDATLIEGARRLCQI
CEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]