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The map label for this gene is dnaA [H]

Identifier: 91781385

GI number: 91781385

Start: 192

End: 1826

Strand: Direct

Name: dnaA [H]

Synonym: Bxe_A4462

Alternate gene names: 91781385

Gene position: 192-1826 (Clockwise)

Preceding gene: NA

Following gene: 91781386

Centisome position: 0.0

GC content: 62.81

Gene sequence:

>1635_bases
ATGAACGATTTCTGGCAACACTGTTCCGCATTGCTGGAGCGTGAGCTGACGCCCCAGCAGTACGTGACGTGGATCAAACC
GTTGGCCCCGGTCGCCTTCGACGCCGCTGCGAACACGCTTAGCATCGCTGCGCCGAACCGTTTCAAGCTCGACTGGGTCA
AGAGCCAGTTCTCCGGCCGCATCGCCGATATGGCCCGCGATTTCTGGCATACCCCCATCGACGTCCAGTTCGTGCTCGAC
CCGAAAGCCGGCATGCGCGCCCCCGCGGCAGCCGCGCCGGCACCGGCTTCCGCGCGTCCGGCTTCCGCGCCTGGCTCGAT
GGGCGGTAGCGCCGGCAACGGCGCTGCGGTGGACGCGGCTGTCGGCGCCGTGCAAGCCGCGCAGACCGCGCGCGCAAACG
GCGCGAATAGCGCGAACAACGCGATGGCCAACCTCAACGCGAATGCCCGCGCGGCGGCCGAACAGAACGCAAACGCACGC
GCCGCGGCCGAAGATTCCGCCGACCTCGATCTGCCCAGCCTCGACGCGAACGAAGCCGCGGCCGCCCGCCGCACGTGGCG
CCCAGGCCAGAGCGCCGGTTCGAACGGCAACGGCGAGACCGACTCGATGTACGAGCGCTCCAAACTGAACCCGGTTCTGA
CCTTCGACAACTTCGTGACCGGTAAGGCCAACCAGTTGGCGCGCGCCGCGGCGATTCAGGTCGCGGACAATCCCGGCATC
TCGTACAACCCGCTGTTTCTGTATGGCGGCGTGGGTCTGGGCAAGACCCACCTGATCCACGCGATCGGCAACCAGCTTCT
GATGGACAAGGCGGGCGCACGGATTCGCTACATCCACGCGGAACAGTACGTGTCCGACGTAGTGAAGGCGTACCAGCGCA
AGGCGTTTGACGATTTCAAGCGCTACTACCACTCGCTCGACCTGCTGCTGATCGACGATATTCAGTTTTTCTCCGGCAAG
TCGCGCACACAAGAGGAATTCTTCTACGCGTTTGAGGCGCTGGTCGCCAACAAGGCGCAGGTGATCATCACCAGCGACAC
GTATCCGAAGGAAATTTCGGGTATCGACGACCGCCTGATCTCGCGCTTCGACTCCGGCCTGACCGTCGCAATCGAGCCGC
CCGAGCTGGAAATGCGCGTCGCGATTCTGATGCGCAAGGCGCAATCCGAGTTCGTGAGCCTGAATGAAGACGTCGCGTTC
TTCGTCGCCAAACACTTGCGTTCGAACGTGCGTGAACTCGAAGGCGCGCTGCGCAAGATCCTCGCGTATTCGAAGTTCCA
CGGCCGCGAAATCACGATCGAAGTCACCAAAGAAGCGCTGAAAGACCTGCTGACGGTGCAGAACCGGCAGATTTCGGTGG
AGAACATCCAGAAGACCACGGCTGACTTCTACAGTATCAAGGTCGCGGACATGTATTCGAAGAAGCGTCCGGCGAACATT
GCGCGGCCGCGGCAGATCGCCATGTATCTGGCGAAGGAGCTGACCCAGAAGAGCTTGCCGGAAATCGGCGAGCTGTTCGG
CGGGCGCGACCACACCACGGTGCTGCACGCGGTGCGCAAAATTGCCGACGAGCGCAGCAAGGACGCGCAACTGAACCACG
AACTGCATGTGCTGGAGCAGACGCTGAAGGGCTGA

Upstream 100 bases:

>100_bases
GAGCCATTGCGCCTGGTTAGTCTGGCTGCTCAGGGCCTTGTTGCGCGCGCGCGACAGGGGCAGCGGCAACCGCCGTGCAC
ACCATAACGACAGCAACTCG

Downstream 100 bases:

>100_bases
GCGGGCTGTCTGGAAAAAACGACCTGTTTATTTCCAAACTCGCCCCCATTTTAGTGAGGCGGTTCTGTTTTCAGGCACAA
TACAGGTTTAACCGCCCGGC

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MNDFWQHCSALLERELTPQQYVTWIKPLAPVAFDAAANTLSIAAPNRFKLDWVKSQFSGRIADMARDFWHTPIDVQFVLD
PKAGMRAPAAAAPAPASARPASAPGSMGGSAGNGAAVDAAVGAVQAAQTARANGANSANNAMANLNANARAAAEQNANAR
AAAEDSADLDLPSLDANEAAAARRTWRPGQSAGSNGNGETDSMYERSKLNPVLTFDNFVTGKANQLARAAAIQVADNPGI
SYNPLFLYGGVGLGKTHLIHAIGNQLLMDKAGARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGK
SRTQEEFFYAFEALVANKAQVIITSDTYPKEISGIDDRLISRFDSGLTVAIEPPELEMRVAILMRKAQSEFVSLNEDVAF
FVAKHLRSNVRELEGALRKILAYSKFHGREITIEVTKEALKDLLTVQNRQISVENIQKTTADFYSIKVADMYSKKRPANI
ARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQTLKG

Sequences:

>Translated_544_residues
MNDFWQHCSALLERELTPQQYVTWIKPLAPVAFDAAANTLSIAAPNRFKLDWVKSQFSGRIADMARDFWHTPIDVQFVLD
PKAGMRAPAAAAPAPASARPASAPGSMGGSAGNGAAVDAAVGAVQAAQTARANGANSANNAMANLNANARAAAEQNANAR
AAAEDSADLDLPSLDANEAAAARRTWRPGQSAGSNGNGETDSMYERSKLNPVLTFDNFVTGKANQLARAAAIQVADNPGI
SYNPLFLYGGVGLGKTHLIHAIGNQLLMDKAGARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGK
SRTQEEFFYAFEALVANKAQVIITSDTYPKEISGIDDRLISRFDSGLTVAIEPPELEMRVAILMRKAQSEFVSLNEDVAF
FVAKHLRSNVRELEGALRKILAYSKFHGREITIEVTKEALKDLLTVQNRQISVENIQKTTADFYSIKVADMYSKKRPANI
ARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQTLKG
>Mature_544_residues
MNDFWQHCSALLERELTPQQYVTWIKPLAPVAFDAAANTLSIAAPNRFKLDWVKSQFSGRIADMARDFWHTPIDVQFVLD
PKAGMRAPAAAAPAPASARPASAPGSMGGSAGNGAAVDAAVGAVQAAQTARANGANSANNAMANLNANARAAAEQNANAR
AAAEDSADLDLPSLDANEAAAARRTWRPGQSAGSNGNGETDSMYERSKLNPVLTFDNFVTGKANQLARAAAIQVADNPGI
SYNPLFLYGGVGLGKTHLIHAIGNQLLMDKAGARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGK
SRTQEEFFYAFEALVANKAQVIITSDTYPKEISGIDDRLISRFDSGLTVAIEPPELEMRVAILMRKAQSEFVSLNEDVAF
FVAKHLRSNVRELEGALRKILAYSKFHGREITIEVTKEALKDLLTVQNRQISVENIQKTTADFYSIKVADMYSKKRPANI
ARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQTLKG

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=539, Percent_Identity=46.7532467532467, Blast_Score=447, Evalue=1e-127,
Organism=Escherichia coli, GI226510964, Length=233, Percent_Identity=26.6094420600858, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 59606; Mature: 59606

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDFWQHCSALLERELTPQQYVTWIKPLAPVAFDAAANTLSIAAPNRFKLDWVKSQFSGR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEHHHHHHHHCCH
IADMARDFWHTPIDVQFVLDPKAGMRAPAAAAPAPASARPASAPGSMGGSAGNGAAVDAA
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
VGAVQAAQTARANGANSANNAMANLNANARAAAEQNANARAAAEDSADLDLPSLDANEAA
HHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHH
AARRTWRPGQSAGSNGNGETDSMYERSKLNPVLTFDNFVTGKANQLARAAAIQVADNPGI
HHHHCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHEEEECCCCC
SYNPLFLYGGVGLGKTHLIHAIGNQLLMDKAGARIRYIHAEQYVSDVVKAYQRKAFDDFK
CCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
RYYHSLDLLLIDDIQFFSGKSRTQEEFFYAFEALVANKAQVIITSDTYPKEISGIDDRLI
HHHHHCCEEEEECHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHCCHHHHHH
SRFDSGLTVAIEPPELEMRVAILMRKAQSEFVSLNEDVAFFVAKHLRSNVRELEGALRKI
HHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAYSKFHGREITIEVTKEALKDLLTVQNRQISVENIQKTTADFYSIKVADMYSKKRPANI
HHHHHCCCCEEEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEHHHHCCCCCCCC
ARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQ
CCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TLKG
HHCC
>Mature Secondary Structure
MNDFWQHCSALLERELTPQQYVTWIKPLAPVAFDAAANTLSIAAPNRFKLDWVKSQFSGR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEHHHHHHHHCCH
IADMARDFWHTPIDVQFVLDPKAGMRAPAAAAPAPASARPASAPGSMGGSAGNGAAVDAA
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
VGAVQAAQTARANGANSANNAMANLNANARAAAEQNANARAAAEDSADLDLPSLDANEAA
HHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHH
AARRTWRPGQSAGSNGNGETDSMYERSKLNPVLTFDNFVTGKANQLARAAAIQVADNPGI
HHHHCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHEEEECCCCC
SYNPLFLYGGVGLGKTHLIHAIGNQLLMDKAGARIRYIHAEQYVSDVVKAYQRKAFDDFK
CCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
RYYHSLDLLLIDDIQFFSGKSRTQEEFFYAFEALVANKAQVIITSDTYPKEISGIDDRLI
HHHHHCCEEEEECHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHCCHHHHHH
SRFDSGLTVAIEPPELEMRVAILMRKAQSEFVSLNEDVAFFVAKHLRSNVRELEGALRKI
HHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAYSKFHGREITIEVTKEALKDLLTVQNRQISVENIQKTTADFYSIKVADMYSKKRPANI
HHHHHCCCCEEEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEHHHHCCCCCCCC
ARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQ
CCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TLKG
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA