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The map label for this gene is frr [H]

Identifier: 89898769

GI number: 89898769

Start: 1110932

End: 1111474

Strand: Direct

Name: frr [H]

Synonym: CF0962

Alternate gene names: 89898769

Gene position: 1110932-1111474 (Clockwise)

Preceding gene: 89898768

Following gene: 89898770

Centisome position: 95.26

GC content: 38.86

Gene sequence:

>543_bases
ATGTCCATTTTAGCTGATACTGAAAAGAAAATGGCTACAGCTTTGGAATTCTTCCAGAAAGAAATCAGAGCATTTAGAAC
AGGAAAAGCTCATCCTGCTTTAGTAGAAACTGTTACAGTAGATGTATATGGAACCACGATGAGGCTATCTGATTTAGCCT
CTATTTCTGTAGCTGACACACGTCAGTTGGTAATTTCTCCTTATGACGCAAATAACGTCTCTGCAATATCCAAGGGCATT
ATTGCTGCAAATTTAAATTTGCAACCCGATGCAGAAGGTGCCATTATACGCATTAAGATTCCTGAGCCTACTGCGGAATA
CAGAAATGAAGTTATCAAACAACTACGCCGCAAATCAGAGGAAGCGAAAGTAACGATTCGCAATGTGCGCAGGGAAGCTA
ACGATAAGTTAAAAAAAGATTCTGACTTAACAGAAGACGCTGTTAAAGGCATGGAAAAAAAGATCCAAGAATTAACAGAT
AAGTTCTGTAAGCAAATCGACGAAATGTCTAAGCAAAAAGAAGCGGACCTTTCGTCAATATGA

Upstream 100 bases:

>100_bases
TCTCATATTCCTATTCGGGTCTTTAGCTTTGTTAAACATTCTCTAGAGCAGGCTATTTTTGATGAGCATATCGGAACATT
AATTTGTGAGGACGCTTAGC

Downstream 100 bases:

>100_bases
TAAGTTCTGTTTCTTCTTATGAGCAGTCTTTATCTGCTTCTCTTTCTTTGGTTTTTCATGAAAAACAAAGAGAGGAAAAG
ATTGCTCTAAAGGAGAAGAA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MSILADTEKKMATALEFFQKEIRAFRTGKAHPALVETVTVDVYGTTMRLSDLASISVADTRQLVISPYDANNVSAISKGI
IAANLNLQPDAEGAIIRIKIPEPTAEYRNEVIKQLRRKSEEAKVTIRNVRREANDKLKKDSDLTEDAVKGMEKKIQELTD
KFCKQIDEMSKQKEADLSSI

Sequences:

>Translated_180_residues
MSILADTEKKMATALEFFQKEIRAFRTGKAHPALVETVTVDVYGTTMRLSDLASISVADTRQLVISPYDANNVSAISKGI
IAANLNLQPDAEGAIIRIKIPEPTAEYRNEVIKQLRRKSEEAKVTIRNVRREANDKLKKDSDLTEDAVKGMEKKIQELTD
KFCKQIDEMSKQKEADLSSI
>Mature_179_residues
SILADTEKKMATALEFFQKEIRAFRTGKAHPALVETVTVDVYGTTMRLSDLASISVADTRQLVISPYDANNVSAISKGII
AANLNLQPDAEGAIIRIKIPEPTAEYRNEVIKQLRRKSEEAKVTIRNVRREANDKLKKDSDLTEDAVKGMEKKIQELTDK
FCKQIDEMSKQKEADLSSI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI291042689, Length=148, Percent_Identity=29.7297297297297, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI20270317, Length=166, Percent_Identity=24.6987951807229, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1786368, Length=178, Percent_Identity=39.3258426966292, Blast_Score=129, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321827, Length=186, Percent_Identity=24.7311827956989, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20155; Mature: 20024

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILADTEKKMATALEFFQKEIRAFRTGKAHPALVETVTVDVYGTTMRLSDLASISVADT
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHEEEEEEECCHHHHHHHHHHHHCCC
RQLVISPYDANNVSAISKGIIAANLNLQPDAEGAIIRIKIPEPTAEYRNEVIKQLRRKSE
CEEEECCCCCCCHHHHHCCEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCH
EAKVTIRNVRREANDKLKKDSDLTEDAVKGMEKKIQELTDKFCKQIDEMSKQKEADLSSI
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SILADTEKKMATALEFFQKEIRAFRTGKAHPALVETVTVDVYGTTMRLSDLASISVADT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHEEEEEEECCHHHHHHHHHHHHCCC
RQLVISPYDANNVSAISKGIIAANLNLQPDAEGAIIRIKIPEPTAEYRNEVIKQLRRKSE
CEEEECCCCCCCHHHHHCCEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCH
EAKVTIRNVRREANDKLKKDSDLTEDAVKGMEKKIQELTDKFCKQIDEMSKQKEADLSSI
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA