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The map label for this gene is pyrH [H]

Identifier: 89898768

GI number: 89898768

Start: 1110208

End: 1110930

Strand: Direct

Name: pyrH [H]

Synonym: CF0961

Alternate gene names: 89898768

Gene position: 1110208-1110930 (Clockwise)

Preceding gene: 89898767

Following gene: 89898769

Centisome position: 95.2

GC content: 40.8

Gene sequence:

>723_bases
ATGTCTAAACGAATAACACGAGTCTTATTTAAGATTTCTGGAGAGTCTCTCTCAACAGACAGCGGAAACCGGATTGATGA
AGTTCGTTTATCCAGACTAGTAGCAGAATTACGCGCGGTCCGTAATTGTGATATTGAAACGGCTCTTGTGATAGGCGGAG
GAAACATCATTAGAGGTCTTGCTCAGCAAAAAGAATTACAAATTAATCGAGTATCTGCAGACCAAATGGGAATGCTAGCG
ACTTTAATTAATGGTATGGCCGTAGCTGATGCTTTAAAAGCTGATGATATTCCTTGTTTATTAACCTCTACGCTTTCTTG
CCCCCAATTAGCAGACTTATACACTCCTCAAAAATCTGCGGAAGCCTTAAGCCAAGGCAAAGTTTTAATCTGCACAACAG
GAGCAGGATCTCCTTATTTAACGACTGACACAGGAGCAGCTTTGCGTGCCTGTGAGTTAAAAGCTGATTTGCTTCTCAAA
GCCACTATGCATGTTGACGGGGTTTACGATAAAGACCCTAGGGAATTTAGTGATGCTGTAAAATACAATCGCATTAGCTA
TAAAGAGGTTTTGTCTCGCGGATTAGGCATTATGGATGCTTCTGCTATATCTCTGTGTATGGATTCTCATATTCCTATTC
GGGTCTTTAGCTTTGTTAAACATTCTCTAGAGCAGGCTATTTTTGATGAGCATATCGGAACATTAATTTGTGAGGACGCT
TAG

Upstream 100 bases:

>100_bases
TCAACATTTAATTAACGGCGTCAGCAAGACTAGTGGCAATTCCGTCGAAGTGAAAGAATTCATTTTATGGAAAATAGGTG
CTTAATAAGCAAGAGGAACT

Downstream 100 bases:

>100_bases
CATGTCCATTTTAGCTGATACTGAAAAGAAAATGGCTACAGCTTTGGAATTCTTCCAGAAAGAAATCAGAGCATTTAGAA
CAGGAAAAGCTCATCCTGCT

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSKRITRVLFKISGESLSTDSGNRIDEVRLSRLVAELRAVRNCDIETALVIGGGNIIRGLAQQKELQINRVSADQMGMLA
TLINGMAVADALKADDIPCLLTSTLSCPQLADLYTPQKSAEALSQGKVLICTTGAGSPYLTTDTGAALRACELKADLLLK
ATMHVDGVYDKDPREFSDAVKYNRISYKEVLSRGLGIMDASAISLCMDSHIPIRVFSFVKHSLEQAIFDEHIGTLICEDA

Sequences:

>Translated_240_residues
MSKRITRVLFKISGESLSTDSGNRIDEVRLSRLVAELRAVRNCDIETALVIGGGNIIRGLAQQKELQINRVSADQMGMLA
TLINGMAVADALKADDIPCLLTSTLSCPQLADLYTPQKSAEALSQGKVLICTTGAGSPYLTTDTGAALRACELKADLLLK
ATMHVDGVYDKDPREFSDAVKYNRISYKEVLSRGLGIMDASAISLCMDSHIPIRVFSFVKHSLEQAIFDEHIGTLICEDA
>Mature_239_residues
SKRITRVLFKISGESLSTDSGNRIDEVRLSRLVAELRAVRNCDIETALVIGGGNIIRGLAQQKELQINRVSADQMGMLAT
LINGMAVADALKADDIPCLLTSTLSCPQLADLYTPQKSAEALSQGKVLICTTGAGSPYLTTDTGAALRACELKADLLLKA
TMHVDGVYDKDPREFSDAVKYNRISYKEVLSRGLGIMDASAISLCMDSHIPIRVFSFVKHSLEQAIFDEHIGTLICEDA

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=233, Percent_Identity=39.9141630901288, Blast_Score=167, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25992; Mature: 25861

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRITRVLFKISGESLSTDSGNRIDEVRLSRLVAELRAVRNCDIETALVIGGGNIIRGL
CCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHH
AQQKELQINRVSADQMGMLATLINGMAVADALKADDIPCLLTSTLSCPQLADLYTPQKSA
HHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHCCCCHHH
EALSQGKVLICTTGAGSPYLTTDTGAALRACELKADLLLKATMHVDGVYDKDPREFSDAV
HHHHCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
KYNRISYKEVLSRGLGIMDASAISLCMDSHIPIRVFSFVKHSLEQAIFDEHIGTLICEDA
HHCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCC
>Mature Secondary Structure 
SKRITRVLFKISGESLSTDSGNRIDEVRLSRLVAELRAVRNCDIETALVIGGGNIIRGL
CHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHH
AQQKELQINRVSADQMGMLATLINGMAVADALKADDIPCLLTSTLSCPQLADLYTPQKSA
HHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHCCCCHHH
EALSQGKVLICTTGAGSPYLTTDTGAALRACELKADLLLKATMHVDGVYDKDPREFSDAV
HHHHCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
KYNRISYKEVLSRGLGIMDASAISLCMDSHIPIRVFSFVKHSLEQAIFDEHIGTLICEDA
HHCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA