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The map label for this gene is uhpC [H]

Identifier: 89898737

GI number: 89898737

Start: 1073036

End: 1074406

Strand: Direct

Name: uhpC [H]

Synonym: CF0930

Alternate gene names: 89898737

Gene position: 1073036-1074406 (Clockwise)

Preceding gene: 89898731

Following gene: 89898738

Centisome position: 92.01

GC content: 41.28

Gene sequence:

>1371_bases
ATGATGAATATTTGGACCAAATTCTTTCAGCCTCCCAAGCCCATTAAAGAACTTGATGATCCAGAGTTAGTCAAAAAACA
ATACAAGTATTGGAGAATTCGAATCTTCTACAGCATGTTTATAGGGTATGTCTTCTACTATTTCACAAGGAAGAGCTTTA
CCTTTGCCATGCCTACATTGATGACAGACCTAGGTTTTGATAAAGCACAACTAGGAATCATCGGAAGTACGTTATACATC
AGTTATGGCATCAGTAAATTCGTTAGTGGTGTTATGTCTGATCAGTCAAATCCTCGCTATTTCATGGCTGTGGGTTTAAT
TATCACAGGATTCACTAATATCTTCTTCGGAATGTCCTCCTCTATTCTCTTATTTGCTTTATGGTGGGGGCTTAATGGTT
GGTTCCAAGGATGGGGCTGGCCACCATGCGCACGTTTATTAACCCACTGGTATTCAAAATCTGAAAGAGGAACCTGGTGG
AGCGTCTGGAGTACATCGCATAATATTGGCGGCGCCTTGATTCCTATTCTTACAGGATTTGCTATTGATTGCTGTGGTTG
GCGTGGAGCAATGTTCATCCCCGGCATTCTATGCATTATCATAGGATTTGTTTTAATTAACCGCCTTCGTGACACACCCC
AGTCACTAGGTCTTCCAGCCATTGAAAAATACAGAAAAAAACAAGAATCTAGAAAACACGAAGAAACAACAGCAGATATT
CTAGAAGAAGAAGCTGAGAAGGAACTATCGACTAGAGAGATTCTTCTTACTTATGTTTTGAAGAACAAGTGGATCTGGTT
ATTATCTTTCGCCTCATTCTTCATTTATGTTGTCCGTATGGCTGTAAATGACTGGAGCGCTCTATTTCTTATTGAAACCA
AACGTTATGCTGCTGTTAAGGCAAATTTCTGTGTTTCTTTATTTGAGATCGGAGGTCTTTTCGGCATGCTAATCGCTGGA
TGGTTATCTGATAAGATCACCAAAGGGAAACGCGGCCCGATGAATGTTGTCTTTTCTTTAGGGTTGTTATTTTCAATTTT
GGGCATGTGGTTAAGTCGCTCTCAAGGTATGTGGTGGTTAGACGGCACCCTGCTCTTTGTTATCGGTTTTTTCTTATTCG
GCCCACAAATGATGATTGGTTTAGCTGCTGCTGAATTATCTCATAAAAAGGCTGCGGGTACCGCTAGCGGTTTCGCTGGC
TGGTTTGCTTATTTTGGAGCAGCGTTTGCTGGTTATCCACTAGGAAAAATAGCTCAAGATTGGGGCTGGAAAGGTTTCTT
TGTTGCTCTACTAGGCTGCGCTTTAATCGCTCTGGTCTTATTCCTACCCACATGGAATGCCTCCGAGAGAAGTTTACAAA
CTAAAAAGTAA

Upstream 100 bases:

>100_bases
ACAGGGGACTATTACTCTCTTGTTTTTTCATTGCCCATATGTTAACCTCAGGTCGTCCCTCTCCACTGAAACTATATTAA
ATATTTAAACATGAGATCTT

Downstream 100 bases:

>100_bases
TACGGGTTGACACGAGGGATTACTTGTGACTTGGATACCTCTTCATTGTCATTCTCAATATTCTATTTTAGATGCTACAA
GCTCTATTAAGAGCTTTGTA

Product: hexosphosphate transport

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MMNIWTKFFQPPKPIKELDDPELVKKQYKYWRIRIFYSMFIGYVFYYFTRKSFTFAMPTLMTDLGFDKAQLGIIGSTLYI
SYGISKFVSGVMSDQSNPRYFMAVGLIITGFTNIFFGMSSSILLFALWWGLNGWFQGWGWPPCARLLTHWYSKSERGTWW
SVWSTSHNIGGALIPILTGFAIDCCGWRGAMFIPGILCIIIGFVLINRLRDTPQSLGLPAIEKYRKKQESRKHEETTADI
LEEEAEKELSTREILLTYVLKNKWIWLLSFASFFIYVVRMAVNDWSALFLIETKRYAAVKANFCVSLFEIGGLFGMLIAG
WLSDKITKGKRGPMNVVFSLGLLFSILGMWLSRSQGMWWLDGTLLFVIGFFLFGPQMMIGLAAAELSHKKAAGTASGFAG
WFAYFGAAFAGYPLGKIAQDWGWKGFFVALLGCALIALVLFLPTWNASERSLQTKK

Sequences:

>Translated_456_residues
MMNIWTKFFQPPKPIKELDDPELVKKQYKYWRIRIFYSMFIGYVFYYFTRKSFTFAMPTLMTDLGFDKAQLGIIGSTLYI
SYGISKFVSGVMSDQSNPRYFMAVGLIITGFTNIFFGMSSSILLFALWWGLNGWFQGWGWPPCARLLTHWYSKSERGTWW
SVWSTSHNIGGALIPILTGFAIDCCGWRGAMFIPGILCIIIGFVLINRLRDTPQSLGLPAIEKYRKKQESRKHEETTADI
LEEEAEKELSTREILLTYVLKNKWIWLLSFASFFIYVVRMAVNDWSALFLIETKRYAAVKANFCVSLFEIGGLFGMLIAG
WLSDKITKGKRGPMNVVFSLGLLFSILGMWLSRSQGMWWLDGTLLFVIGFFLFGPQMMIGLAAAELSHKKAAGTASGFAG
WFAYFGAAFAGYPLGKIAQDWGWKGFFVALLGCALIALVLFLPTWNASERSLQTKK
>Mature_456_residues
MMNIWTKFFQPPKPIKELDDPELVKKQYKYWRIRIFYSMFIGYVFYYFTRKSFTFAMPTLMTDLGFDKAQLGIIGSTLYI
SYGISKFVSGVMSDQSNPRYFMAVGLIITGFTNIFFGMSSSILLFALWWGLNGWFQGWGWPPCARLLTHWYSKSERGTWW
SVWSTSHNIGGALIPILTGFAIDCCGWRGAMFIPGILCIIIGFVLINRLRDTPQSLGLPAIEKYRKKQESRKHEETTADI
LEEEAEKELSTREILLTYVLKNKWIWLLSFASFFIYVVRMAVNDWSALFLIETKRYAAVKANFCVSLFEIGGLFGMLIAG
WLSDKITKGKRGPMNVVFSLGLLFSILGMWLSRSQGMWWLDGTLLFVIGFFLFGPQMMIGLAAAELSHKKAAGTASGFAG
WFAYFGAAFAGYPLGKIAQDWGWKGFFVALLGCALIALVLFLPTWNASERSLQTKK

Specific function: Transport protein for sugar phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=446, Percent_Identity=34.7533632286996, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI4503847, Length=446, Percent_Identity=34.7533632286996, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI256219483, Length=446, Percent_Identity=34.7533632286996, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI256219543, Length=467, Percent_Identity=32.1199143468951, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI256219564, Length=372, Percent_Identity=31.7204301075269, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI46361976, Length=472, Percent_Identity=22.0338983050847, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI49619231, Length=402, Percent_Identity=23.134328358209, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI223717983, Length=410, Percent_Identity=23.1707317073171, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI38093649, Length=410, Percent_Identity=23.1707317073171, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI14150047, Length=259, Percent_Identity=21.6216216216216, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87082310, Length=441, Percent_Identity=48.0725623582766, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1788573, Length=448, Percent_Identity=37.5, Blast_Score=309, Evalue=2e-85,
Organism=Escherichia coli, GI2367259, Length=463, Percent_Identity=33.4773218142549, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1789152, Length=430, Percent_Identity=20.9302325581395, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI2367379, Length=332, Percent_Identity=23.1927710843373, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17542316, Length=483, Percent_Identity=23.1884057971014, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17561094, Length=437, Percent_Identity=24.2562929061785, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI133930953, Length=461, Percent_Identity=21.2581344902386, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI133901856, Length=470, Percent_Identity=21.2765957446809, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI133901854, Length=470, Percent_Identity=21.2765957446809, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17539138, Length=299, Percent_Identity=25.752508361204, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17564202, Length=442, Percent_Identity=21.2669683257919, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17564204, Length=379, Percent_Identity=21.8997361477573, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24656861, Length=469, Percent_Identity=24.7334754797441, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24656866, Length=470, Percent_Identity=25.1063829787234, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI45550478, Length=470, Percent_Identity=25.1063829787234, Blast_Score=125, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51852; Mature: 51852

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNIWTKFFQPPKPIKELDDPELVKKQYKYWRIRIFYSMFIGYVFYYFTRKSFTFAMPTL
CCCHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
MTDLGFDKAQLGIIGSTLYISYGISKFVSGVMSDQSNPRYFMAVGLIITGFTNIFFGMSS
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCH
SILLFALWWGLNGWFQGWGWPPCARLLTHWYSKSERGTWWSVWSTSHNIGGALIPILTGF
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHH
AIDCCGWRGAMFIPGILCIIIGFVLINRLRDTPQSLGLPAIEKYRKKQESRKHEETTADI
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LEEEAEKELSTREILLTYVLKNKWIWLLSFASFFIYVVRMAVNDWSALFLIETKRYAAVK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHH
ANFCVSLFEIGGLFGMLIAGWLSDKITKGKRGPMNVVFSLGLLFSILGMWLSRSQGMWWL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
DGTLLFVIGFFLFGPQMMIGLAAAELSHKKAAGTASGFAGWFAYFGAAFAGYPLGKIAQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
WGWKGFFVALLGCALIALVLFLPTWNASERSLQTKK
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MMNIWTKFFQPPKPIKELDDPELVKKQYKYWRIRIFYSMFIGYVFYYFTRKSFTFAMPTL
CCCHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
MTDLGFDKAQLGIIGSTLYISYGISKFVSGVMSDQSNPRYFMAVGLIITGFTNIFFGMSS
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCH
SILLFALWWGLNGWFQGWGWPPCARLLTHWYSKSERGTWWSVWSTSHNIGGALIPILTGF
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHH
AIDCCGWRGAMFIPGILCIIIGFVLINRLRDTPQSLGLPAIEKYRKKQESRKHEETTADI
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LEEEAEKELSTREILLTYVLKNKWIWLLSFASFFIYVVRMAVNDWSALFLIETKRYAAVK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHH
ANFCVSLFEIGGLFGMLIAGWLSDKITKGKRGPMNVVFSLGLLFSILGMWLSRSQGMWWL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
DGTLLFVIGFFLFGPQMMIGLAAAELSHKKAAGTASGFAGWFAYFGAAFAGYPLGKIAQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
WGWKGFFVALLGCALIALVLFLPTWNASERSLQTKK
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]