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The map label for this gene is dnaB [H]

Identifier: 89898689

GI number: 89898689

Start: 1036469

End: 1037920

Strand: Direct

Name: dnaB [H]

Synonym: CF0882

Alternate gene names: 89898689

Gene position: 1036469-1037920 (Clockwise)

Preceding gene: 89898682

Following gene: 89898690

Centisome position: 88.87

GC content: 40.29

Gene sequence:

>1452_bases
ATGACTCACGACTTAGATTGCATCATAAAAACTATGTCAACTCAAATCCAAAAGACCCCTGCACCTGCTTTGCCCAGCCC
CCCTAACTCTAAAGAATCAGAAATGATTGTCCTGGGTTGCATGCTCACTGGAGTTAACTATCTTAATCTAGCAGCAAATC
AGCTTAATGAAGATGATTTTTATTATCTTGAACACAAAATTATCTTCCGCGTTCTTCAAGATGCTTTCAAACACGACAAA
CCCATAGATGTACATCTTGCTGGAGAAGAGCTTAAAAGAAGAAACCACCTTACCGTCATTGGGGGGCCTGGTTACTTAAT
TACCTTAGCAGATTTTGCAGGAACCGCAGCATACATTGAAGAATATATTCAGATCATTCTTTCTAAATCGATTTTAAGAA
AAATGATCCAAACTGCTAAGGAGATAGAGAAAAAGGCAATTGAAGAACCGAAAGACGTTGCTGTGGCCTTGGATGAAGCT
CAGAACGCTTTATTTAAAATTAGCCAAACAACCTCCCTCACACAGTACGTTCTCGTTGCCGACAAACTGCAAGGTTTAGT
TTCCGCCCAAGAAAAACCCTTCCTTGTTCAATTACAGGAAAAACAAGAGTTCTTTCAACAGCACGCACAAAGCGGCGATG
CGTTACCCATTTCCGGCATCCCCACACATTTCCTTGATCTAGACAAAATGATCAATGGTTTTTCTCCTTCTAATTTAATG
ATCCTTGCAGCCCGACCTGCTATGGGGAAAACCGCTCTTGCCCTAAATATCGCAGAAAACATGTGCTTTCAAAGCCGACT
TCCTATAGGAATTTTTTCTCTAGAGATGACTGTTGATCAGCTAATTCACAGAATCATATGCTCTCGGGCTGAAGTAGAAT
CTAGAAAAATCAATGTAGGAGATTTATCCGGTCAGGACTTTCAACGCATTGTTTCTGTTGTAAATGAAATGCAGAAACAT
ACTCTACTTATAGATGATCAACCCGGATTAAAAGTAACCGATCTGAGAGCTCGCGCTCGAAGAATGAAAGAAAGTTATGA
CATTCAATTCTTGATCATTGACTACCTTCAACTTCTTTCCGGTTCAGGGACCCTACGTTCTGCGGAAAGTCGTCAAACTG
AAATTTCAGAAATTTCCAGAATGCTGAAAACTTTAGCTAGGGAATTAAATATTCCTATTCTCTGTCTATCACAGTTATCT
AGAAAAGTGGAAGACAGGGCGAATCATCGGCCTATGATGAGCGATCTTAGAGAAAGTGGAAGCATAGAACAGGATTCTGA
CTTAGTTATGTTCCTATTGCGTCGAGAATATTATGATCCTCATGACAAGCCTGGAACAGCTGAACTTATAGTAGCTAAAA
ACCGTCACGGGTCTATAGGTTCTGTGCCTTTAGTTTTTGAAAAAGAACTTGCAAGATTCAGGAACTATGCAGCTCTTGAA
TTCAACGGGTAG

Upstream 100 bases:

>100_bases
GCTTTCTTCGAGATTTCCCCGCAAGTCCCACCCAAACTTTATCGTCTCCCCGAACCTTATAACTTGAGCATATATTTTCG
ATATCCTAACCTGATCTCGA

Downstream 100 bases:

>100_bases
AAAAATTTTTATAAAATTAATGCAGAACATCTTATTGATATTTGAATCAAGTTTCACAAAAAAATTCATCCCGTTTCTCT
AGTGAGACGAGGTTAAAATC

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 482

Protein sequence:

>483_residues
MTHDLDCIIKTMSTQIQKTPAPALPSPPNSKESEMIVLGCMLTGVNYLNLAANQLNEDDFYYLEHKIIFRVLQDAFKHDK
PIDVHLAGEELKRRNHLTVIGGPGYLITLADFAGTAAYIEEYIQIILSKSILRKMIQTAKEIEKKAIEEPKDVAVALDEA
QNALFKISQTTSLTQYVLVADKLQGLVSAQEKPFLVQLQEKQEFFQQHAQSGDALPISGIPTHFLDLDKMINGFSPSNLM
ILAARPAMGKTALALNIAENMCFQSRLPIGIFSLEMTVDQLIHRIICSRAEVESRKINVGDLSGQDFQRIVSVVNEMQKH
TLLIDDQPGLKVTDLRARARRMKESYDIQFLIIDYLQLLSGSGTLRSAESRQTEISEISRMLKTLARELNIPILCLSQLS
RKVEDRANHRPMMSDLRESGSIEQDSDLVMFLLRREYYDPHDKPGTAELIVAKNRHGSIGSVPLVFEKELARFRNYAALE
FNG

Sequences:

>Translated_483_residues
MTHDLDCIIKTMSTQIQKTPAPALPSPPNSKESEMIVLGCMLTGVNYLNLAANQLNEDDFYYLEHKIIFRVLQDAFKHDK
PIDVHLAGEELKRRNHLTVIGGPGYLITLADFAGTAAYIEEYIQIILSKSILRKMIQTAKEIEKKAIEEPKDVAVALDEA
QNALFKISQTTSLTQYVLVADKLQGLVSAQEKPFLVQLQEKQEFFQQHAQSGDALPISGIPTHFLDLDKMINGFSPSNLM
ILAARPAMGKTALALNIAENMCFQSRLPIGIFSLEMTVDQLIHRIICSRAEVESRKINVGDLSGQDFQRIVSVVNEMQKH
TLLIDDQPGLKVTDLRARARRMKESYDIQFLIIDYLQLLSGSGTLRSAESRQTEISEISRMLKTLARELNIPILCLSQLS
RKVEDRANHRPMMSDLRESGSIEQDSDLVMFLLRREYYDPHDKPGTAELIVAKNRHGSIGSVPLVFEKELARFRNYAALE
FNG
>Mature_482_residues
THDLDCIIKTMSTQIQKTPAPALPSPPNSKESEMIVLGCMLTGVNYLNLAANQLNEDDFYYLEHKIIFRVLQDAFKHDKP
IDVHLAGEELKRRNHLTVIGGPGYLITLADFAGTAAYIEEYIQIILSKSILRKMIQTAKEIEKKAIEEPKDVAVALDEAQ
NALFKISQTTSLTQYVLVADKLQGLVSAQEKPFLVQLQEKQEFFQQHAQSGDALPISGIPTHFLDLDKMINGFSPSNLMI
LAARPAMGKTALALNIAENMCFQSRLPIGIFSLEMTVDQLIHRIICSRAEVESRKINVGDLSGQDFQRIVSVVNEMQKHT
LLIDDQPGLKVTDLRARARRMKESYDIQFLIIDYLQLLSGSGTLRSAESRQTEISEISRMLKTLARELNIPILCLSQLSR
KVEDRANHRPMMSDLRESGSIEQDSDLVMFLLRREYYDPHDKPGTAELIVAKNRHGSIGSVPLVFEKELARFRNYAALEF
NG

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=466, Percent_Identity=37.7682403433476, Blast_Score=294, Evalue=7e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 54398; Mature: 54266

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHDLDCIIKTMSTQIQKTPAPALPSPPNSKESEMIVLGCMLTGVNYLNLAANQLNEDDF
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEHHHHCCHHHHHHHHHCCCCCH
YYLEHKIIFRVLQDAFKHDKPIDVHLAGEELKRRNHLTVIGGPGYLITLADFAGTAAYIE
HHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCCEEEEECCCEEEEEHHHCCHHHHHH
EYIQIILSKSILRKMIQTAKEIEKKAIEEPKDVAVALDEAQNALFKISQTTSLTQYVLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEECHHHHHHHHHHH
DKLQGLVSAQEKPFLVQLQEKQEFFQQHAQSGDALPISGIPTHFLDLDKMINGFSPSNLM
HHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEE
ILAARPAMGKTALALNIAENMCFQSRLPIGIFSLEMTVDQLIHRIICSRAEVESRKINVG
EEEECCCCCCHHEEEEHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCEECCC
DLSGQDFQRIVSVVNEMQKHTLLIDDQPGLKVTDLRARARRMKESYDIQFLIIDYLQLLS
CCCCHHHHHHHHHHHHHHHCEEEEECCCCCEEHHHHHHHHHHHHHCCEEEHHHHHHHHHC
GSGTLRSAESRQTEISEISRMLKTLARELNIPILCLSQLSRKVEDRANHRPMMSDLRESG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHCC
SIEQDSDLVMFLLRREYYDPHDKPGTAELIVAKNRHGSIGSVPLVFEKELARFRNYAALE
CCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCEEEE
FNG
ECC
>Mature Secondary Structure 
THDLDCIIKTMSTQIQKTPAPALPSPPNSKESEMIVLGCMLTGVNYLNLAANQLNEDDF
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEHHHHCCHHHHHHHHHCCCCCH
YYLEHKIIFRVLQDAFKHDKPIDVHLAGEELKRRNHLTVIGGPGYLITLADFAGTAAYIE
HHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCCEEEEECCCEEEEEHHHCCHHHHHH
EYIQIILSKSILRKMIQTAKEIEKKAIEEPKDVAVALDEAQNALFKISQTTSLTQYVLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEECHHHHHHHHHHH
DKLQGLVSAQEKPFLVQLQEKQEFFQQHAQSGDALPISGIPTHFLDLDKMINGFSPSNLM
HHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEE
ILAARPAMGKTALALNIAENMCFQSRLPIGIFSLEMTVDQLIHRIICSRAEVESRKINVG
EEEECCCCCCHHEEEEHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCEECCC
DLSGQDFQRIVSVVNEMQKHTLLIDDQPGLKVTDLRARARRMKESYDIQFLIIDYLQLLS
CCCCHHHHHHHHHHHHHHHCEEEEECCCCCEEHHHHHHHHHHHHHCCEEEHHHHHHHHHC
GSGTLRSAESRQTEISEISRMLKTLARELNIPILCLSQLSRKVEDRANHRPMMSDLRESG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHCC
SIEQDSDLVMFLLRREYYDPHDKPGTAELIVAKNRHGSIGSVPLVFEKELARFRNYAALE
CCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCEEEE
FNG
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]