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The map label for this gene is atpA [H]

Identifier: 89898134

GI number: 89898134

Start: 376132

End: 377898

Strand: Direct

Name: atpA [H]

Synonym: CF0327

Alternate gene names: 89898134

Gene position: 376132-377898 (Clockwise)

Preceding gene: 89898133

Following gene: 89898135

Centisome position: 32.25

GC content: 41.14

Gene sequence:

>1767_bases
ATGGTAGTAACTTCGGGACAAACGACTCAGGGATATGTTGTAGAGGCCTATGGTAATTTATTGCGTGTACGTTTTGATGG
ACACGTACGTCAGGGGGAAGTTGCTTATGTGAGCGTTGATGACACATGGTTAAAGTCGGAAGTTATTGAGGTTGTTGGTC
AAGAGGTCAAAATTCAGGTTTTTGAAGATACTCAAGATGTTTGTCGAGGTGCGTTGGTGACTTTCTCGGGACACTTGTTG
GAAGCTGAATTGGGCCCAGGATTATTGCAAGGGATTTTTGATGGGTTACAAAACCGTCTACAAGTGTTGGCTGAAAGTAG
TTTTTTCTTGAAAAGAGGAGAGTATGTCAATGCTCTTTGTAGGAAAACATTATGGGAATACACGCCAACAGCCGTGGTTG
GAGATGTGCTTGTCCGTGGAGATGCTTTAGGGGTTGTTAAAGAAGGGAACTTTAATCATAAAATTATGGTTCCGTTTTCT
TGTTTTAAAGAAGTAACGATCACTTGGGTGATCTCTGAAGGTGAGTACGGCGTTGATACAGTAATAGCTAAAGCTCGTGA
TGCAGATGGTAAAGAGTATAGCTTTACTATGGTTCAGAAGTGGCCAATTAAGCAGGCTTTTATCCAAGGGGATAAAGTTC
CTAGTCATGAAATTATGGATGTAGGTGTGCGAATTTTGGATACGCACATTCCTGTATTGAAAGGAGGAACCTTCTGCACT
CCTGGTCCTTTTGGCGCGGGGAAAACAGTGTTACAACATCACCTATCTAAGTATTCCTCTGTGGATATTGTTATTCTTTG
TGCTTGTGGAGAGCGTGCCGGTGAAGTTGTAGAGGTTTTGCAAGAGTTCCCACATCTTACAGACCCTCATACTGGAAAAT
CTTTAATGCATAGAACTTGCATTATTTGTAATACATCCTCTATGCCCGTAGCTGCTAGAGAGTCTTCGATTTACCTAGGC
ATTACTATCGCAGAATATTATAGACAAATGGGTCTGCATATACTTTTGCTAGCAGATTCAACATCGCGATGGGCTCAAGC
TTTAAGGGAGATTTCAGGAAGATTAGAAGAAATTCCAGGAGAAGAAGCTTTTCCAGCTTATTTAGCATCAAGAATAGCTG
CTTTCTATGAACGTGGCGGTGCTGTACGTATGAAAGATGGTTCGGAAGGTTCTTTAACAATATGCGGTGCTGTATCTCCT
GCTGGAGGAAATTTTGAAGAGCCTGTAACGCAAGCGACTCTATCCGTAGTGGGAGCATTTTGCGGTCTTTCTAAGGCTCG
TGCTGACGCTAGACGTTATCCCTCCATTGATCCTATGATCTCTTGGTCGAAGTATTTAGATCAAGTTGGAGAGATCTTAG
AAAATAAGGTTCATGGATGGGGAGAATCTGTAAAAAAAGCCAATCATTTCCTCCGTGAAGGATCTGAGATTGGTAAACGC
ATGGAAGTTGTTGGAGAAGAGGGTATCTCTATGGAAGACATGGAGATTTATCTCAAAGCAGAGTTATATGACTTCTGTTA
TCTTCAACAAAATGCTTTCGATGCTGTGGATTGTTATTGTCCTTTTGATCGGCAAATTGAGTTGTTTTCATTAATGCGTC
GAATTTTTGACGCGAAATTTAGCTTCGATTGTCCCGATAATGCGAGAAGTTTCTTTCTTGAATTGCAAAGTAAAATCAAA
ACCTTAAATGGCCGAAAGTTTCTTTCTGATGAATACAAGGAAGGGATGGAAGTGGTTCTTAGGTTGATAGAGACGAAGAA
GATATAA

Upstream 100 bases:

>100_bases
TTTTAGCGAAGGTTGCAGCATATTTATTTGCTATTCGCAATGGCATGGTGAATTTAGATAAAGGAAGAAACATTATTAAT
TCTATGGAAAAGGCGATCAC

Downstream 100 bases:

>100_bases
ACAGCGTAAAGGTTATGCAGACAATATATACAAAAATTACCGACATCAAAGGAAACTTAATAACCGTAGAAGCTGAGGGA
GCGCGTCTAGGAGAATTGGC

Product: V-type ATP synthase subunit A

Products: NA

Alternate protein names: V-ATPase subunit A [H]

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MVVTSGQTTQGYVVEAYGNLLRVRFDGHVRQGEVAYVSVDDTWLKSEVIEVVGQEVKIQVFEDTQDVCRGALVTFSGHLL
EAELGPGLLQGIFDGLQNRLQVLAESSFFLKRGEYVNALCRKTLWEYTPTAVVGDVLVRGDALGVVKEGNFNHKIMVPFS
CFKEVTITWVISEGEYGVDTVIAKARDADGKEYSFTMVQKWPIKQAFIQGDKVPSHEIMDVGVRILDTHIPVLKGGTFCT
PGPFGAGKTVLQHHLSKYSSVDIVILCACGERAGEVVEVLQEFPHLTDPHTGKSLMHRTCIICNTSSMPVAARESSIYLG
ITIAEYYRQMGLHILLLADSTSRWAQALREISGRLEEIPGEEAFPAYLASRIAAFYERGGAVRMKDGSEGSLTICGAVSP
AGGNFEEPVTQATLSVVGAFCGLSKARADARRYPSIDPMISWSKYLDQVGEILENKVHGWGESVKKANHFLREGSEIGKR
MEVVGEEGISMEDMEIYLKAELYDFCYLQQNAFDAVDCYCPFDRQIELFSLMRRIFDAKFSFDCPDNARSFFLELQSKIK
TLNGRKFLSDEYKEGMEVVLRLIETKKI

Sequences:

>Translated_588_residues
MVVTSGQTTQGYVVEAYGNLLRVRFDGHVRQGEVAYVSVDDTWLKSEVIEVVGQEVKIQVFEDTQDVCRGALVTFSGHLL
EAELGPGLLQGIFDGLQNRLQVLAESSFFLKRGEYVNALCRKTLWEYTPTAVVGDVLVRGDALGVVKEGNFNHKIMVPFS
CFKEVTITWVISEGEYGVDTVIAKARDADGKEYSFTMVQKWPIKQAFIQGDKVPSHEIMDVGVRILDTHIPVLKGGTFCT
PGPFGAGKTVLQHHLSKYSSVDIVILCACGERAGEVVEVLQEFPHLTDPHTGKSLMHRTCIICNTSSMPVAARESSIYLG
ITIAEYYRQMGLHILLLADSTSRWAQALREISGRLEEIPGEEAFPAYLASRIAAFYERGGAVRMKDGSEGSLTICGAVSP
AGGNFEEPVTQATLSVVGAFCGLSKARADARRYPSIDPMISWSKYLDQVGEILENKVHGWGESVKKANHFLREGSEIGKR
MEVVGEEGISMEDMEIYLKAELYDFCYLQQNAFDAVDCYCPFDRQIELFSLMRRIFDAKFSFDCPDNARSFFLELQSKIK
TLNGRKFLSDEYKEGMEVVLRLIETKKI
>Mature_588_residues
MVVTSGQTTQGYVVEAYGNLLRVRFDGHVRQGEVAYVSVDDTWLKSEVIEVVGQEVKIQVFEDTQDVCRGALVTFSGHLL
EAELGPGLLQGIFDGLQNRLQVLAESSFFLKRGEYVNALCRKTLWEYTPTAVVGDVLVRGDALGVVKEGNFNHKIMVPFS
CFKEVTITWVISEGEYGVDTVIAKARDADGKEYSFTMVQKWPIKQAFIQGDKVPSHEIMDVGVRILDTHIPVLKGGTFCT
PGPFGAGKTVLQHHLSKYSSVDIVILCACGERAGEVVEVLQEFPHLTDPHTGKSLMHRTCIICNTSSMPVAARESSIYLG
ITIAEYYRQMGLHILLLADSTSRWAQALREISGRLEEIPGEEAFPAYLASRIAAFYERGGAVRMKDGSEGSLTICGAVSP
AGGNFEEPVTQATLSVVGAFCGLSKARADARRYPSIDPMISWSKYLDQVGEILENKVHGWGESVKKANHFLREGSEIGKR
MEVVGEEGISMEDMEIYLKAELYDFCYLQQNAFDAVDCYCPFDRQIELFSLMRRIFDAKFSFDCPDNARSFFLELQSKIK
TLNGRKFLSDEYKEGMEVVLRLIETKKI

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit [H]

COG id: COG1155

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI19913424, Length=510, Percent_Identity=41.3725490196078, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI19913426, Length=231, Percent_Identity=26.4069264069264, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI19913428, Length=260, Percent_Identity=25.3846153846154, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI32189394, Length=241, Percent_Identity=28.2157676348548, Blast_Score=83, Evalue=8e-16,
Organism=Escherichia coli, GI1788251, Length=244, Percent_Identity=26.2295081967213, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790170, Length=253, Percent_Identity=25.296442687747, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1790172, Length=241, Percent_Identity=26.1410788381743, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17565854, Length=510, Percent_Identity=40.7843137254902, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17510931, Length=206, Percent_Identity=29.126213592233, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI25144756, Length=243, Percent_Identity=28.3950617283951, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17570191, Length=206, Percent_Identity=27.1844660194175, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320016, Length=274, Percent_Identity=42.3357664233577, Blast_Score=223, Evalue=5e-59,
Organism=Saccharomyces cerevisiae, GI6319603, Length=240, Percent_Identity=26.6666666666667, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322581, Length=240, Percent_Identity=27.5, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI20129479, Length=511, Percent_Identity=40.9001956947162, Blast_Score=382, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24583988, Length=502, Percent_Identity=40.4382470119522, Blast_Score=376, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24583986, Length=502, Percent_Identity=40.4382470119522, Blast_Score=376, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24583984, Length=502, Percent_Identity=40.4382470119522, Blast_Score=376, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24583992, Length=493, Percent_Identity=39.9594320486815, Blast_Score=371, Evalue=1e-103,
Organism=Drosophila melanogaster, GI28574560, Length=246, Percent_Identity=30.0813008130081, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24638766, Length=287, Percent_Identity=26.4808362369338, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281361666, Length=255, Percent_Identity=25.4901960784314, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646341, Length=255, Percent_Identity=25.4901960784314, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17136796, Length=255, Percent_Identity=25.4901960784314, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR000793
- InterPro:   IPR004100
- InterPro:   IPR022878 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 65467; Mature: 65467

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVTSGQTTQGYVVEAYGNLLRVRFDGHVRQGEVAYVSVDDTWLKSEVIEVVGQEVKIQV
CEECCCCCCCCEEEEECCCEEEEEECCCCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEE
FEDTQDVCRGALVTFSGHLLEAELGPGLLQGIFDGLQNRLQVLAESSFFLKRGEYVNALC
ECCHHHHHHHHHHEECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHH
RKTLWEYTPTAVVGDVLVRGDALGVVKEGNFNHKIMVPFSCFKEVTITWVISEGEYGVDT
HHHHHHCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEEHHHHCCEEEEEEEECCCCCHHH
VIAKARDADGKEYSFTMVQKWPIKQAFIQGDKVPSHEIMDVGVRILDTHIPVLKGGTFCT
HHHHCCCCCCCEEEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
PGPFGAGKTVLQHHLSKYSSVDIVILCACGERAGEVVEVLQEFPHLTDPHTGKSLMHRTC
CCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHCEE
IICNTSSMPVAARESSIYLGITIAEYYRQMGLHILLLADSTSRWAQALREISGRLEEIPG
EEECCCCCCCEECCCCEEEEEEHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCC
EEAFPAYLASRIAAFYERGGAVRMKDGSEGSLTICGAVSPAGGNFEEPVTQATLSVVGAF
CCCHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
CGLSKARADARRYPSIDPMISWSKYLDQVGEILENKVHGWGESVKKANHFLREGSEIGKR
HCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHH
MEVVGEEGISMEDMEIYLKAELYDFCYLQQNAFDAVDCYCPFDRQIELFSLMRRIFDAKF
HHHHHCCCCCCCCEEEEEEHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCC
SFDCPDNARSFFLELQSKIKTLNGRKFLSDEYKEGMEVVLRLIETKKI
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVVTSGQTTQGYVVEAYGNLLRVRFDGHVRQGEVAYVSVDDTWLKSEVIEVVGQEVKIQV
CEECCCCCCCCEEEEECCCEEEEEECCCCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEE
FEDTQDVCRGALVTFSGHLLEAELGPGLLQGIFDGLQNRLQVLAESSFFLKRGEYVNALC
ECCHHHHHHHHHHEECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHH
RKTLWEYTPTAVVGDVLVRGDALGVVKEGNFNHKIMVPFSCFKEVTITWVISEGEYGVDT
HHHHHHCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEEHHHHCCEEEEEEEECCCCCHHH
VIAKARDADGKEYSFTMVQKWPIKQAFIQGDKVPSHEIMDVGVRILDTHIPVLKGGTFCT
HHHHCCCCCCCEEEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
PGPFGAGKTVLQHHLSKYSSVDIVILCACGERAGEVVEVLQEFPHLTDPHTGKSLMHRTC
CCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHCEE
IICNTSSMPVAARESSIYLGITIAEYYRQMGLHILLLADSTSRWAQALREISGRLEEIPG
EEECCCCCCCEECCCCEEEEEEHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCC
EEAFPAYLASRIAAFYERGGAVRMKDGSEGSLTICGAVSPAGGNFEEPVTQATLSVVGAF
CCCHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
CGLSKARADARRYPSIDPMISWSKYLDQVGEILENKVHGWGESVKKANHFLREGSEIGKR
HCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHH
MEVVGEEGISMEDMEIYLKAELYDFCYLQQNAFDAVDCYCPFDRQIELFSLMRRIFDAKF
HHHHHCCCCCCCCEEEEEEHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCC
SFDCPDNARSFFLELQSKIKTLNGRKFLSDEYKEGMEVVLRLIETKKI
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA