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The map label for this gene is asd [H]

Identifier: 89898111

GI number: 89898111

Start: 351575

End: 352576

Strand: Direct

Name: asd [H]

Synonym: CF0304

Alternate gene names: 89898111

Gene position: 351575-352576 (Clockwise)

Preceding gene: 89898110

Following gene: 89898112

Centisome position: 30.15

GC content: 41.52

Gene sequence:

>1002_bases
ATGCGTGTGGCTGTTTTGGGAGCTACCGGGCTGGTTGGTCAAAAGTTTATAGCGCTCTTGCATAAATGGTTTCCTTGGCA
GATTTGTGAAGTTGTTGCTTCCGCAACAAAATATAGTCAGACTTACGGTTCTGCATGTATGTGGCAAGAGGCTTTAGGCC
CTATGCCTGAAAGTATGGTTCGTGTGCCTATTCGTAAAATTGAGGAGATCGAGTCTGATATTATAGCATCTTTTTTACCG
GAGCCCGTTGCAGAGTCCCTAGAGACGTATTGCTTGTCTCAGGGGAAGCTAGTTTTTTCTAATGCATCAGCCTATAGGAT
GCACCCTGCAGTTCCTATTATCATTCCAGAAGTAAATCAGGATCATCTGCAACTTGTGGATAAGCAGCCCTTTTCTGGGA
AAATAATTACAAATTCTAATTGTTGTGTTTCCGGTATTGCCCTAGCTTTAGCCCCCTTAGGGGAATTCGGTATAGATCGA
GTAAATATTGTTACTCTGCAGTCTGCCAGTGGAGCTGGGTATCCTGGTGTTTCTTCTATGGATGTTTTGGGAAATACAGT
TCCTCATATAGTAGGAGAAGAAGAAAAAATTCTTAGGGAAACATTAAAGATTTTAGGAAAATGTGAAGAACCTGCGGATT
TCCCTATAACGGTTACCGTGCATCGTGTTCCTGTGGTTTATGGACATACATTAACTTTGCACGTGACTTTTCTTGATGCT
GTCGATATTAAAGATATTCTCTATAGTTATCATTGTAGGAACTCGGAATTTCCTGAAACATATAAGCTTTATGATTCTCC
TTGGCACCCACAAGCAAGAAAAGATCTGACAGATGAGGATATGCGTGTGCATATCGGTCCCATTACTTACGGTGGAGATG
CTCGAACAATAAAGATGAATGTATTGGTACATAATCTTGTTCGAGGGGCTGCGGGCACTTTGTTGAAAAATATGCACAAC
TACTGTTTTCAGAATTCTGGAGAATATGCATGCTCCCAGTAG

Upstream 100 bases:

>100_bases
TGTTTTGCATTATCAACACTCTATTTTAAGTAGCTGTTTTGTTAACCTGCTTTCTTATTCGTTATCACTGATGATATAGT
ATGATTTCAGGAGGCAACAC

Downstream 100 bases:

>100_bases
TGTACAAATTTGGTGGGACGAGTTTAGGAACTGCAGAAAGTATCAAAAAGGTATATGATATTGTCTGCAAAAATACACCG
CGTTTTATTGTTGTCAGTGC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MRVAVLGATGLVGQKFIALLHKWFPWQICEVVASATKYSQTYGSACMWQEALGPMPESMVRVPIRKIEEIESDIIASFLP
EPVAESLETYCLSQGKLVFSNASAYRMHPAVPIIIPEVNQDHLQLVDKQPFSGKIITNSNCCVSGIALALAPLGEFGIDR
VNIVTLQSASGAGYPGVSSMDVLGNTVPHIVGEEEKILRETLKILGKCEEPADFPITVTVHRVPVVYGHTLTLHVTFLDA
VDIKDILYSYHCRNSEFPETYKLYDSPWHPQARKDLTDEDMRVHIGPITYGGDARTIKMNVLVHNLVRGAAGTLLKNMHN
YCFQNSGEYACSQ

Sequences:

>Translated_333_residues
MRVAVLGATGLVGQKFIALLHKWFPWQICEVVASATKYSQTYGSACMWQEALGPMPESMVRVPIRKIEEIESDIIASFLP
EPVAESLETYCLSQGKLVFSNASAYRMHPAVPIIIPEVNQDHLQLVDKQPFSGKIITNSNCCVSGIALALAPLGEFGIDR
VNIVTLQSASGAGYPGVSSMDVLGNTVPHIVGEEEKILRETLKILGKCEEPADFPITVTVHRVPVVYGHTLTLHVTFLDA
VDIKDILYSYHCRNSEFPETYKLYDSPWHPQARKDLTDEDMRVHIGPITYGGDARTIKMNVLVHNLVRGAAGTLLKNMHN
YCFQNSGEYACSQ
>Mature_333_residues
MRVAVLGATGLVGQKFIALLHKWFPWQICEVVASATKYSQTYGSACMWQEALGPMPESMVRVPIRKIEEIESDIIASFLP
EPVAESLETYCLSQGKLVFSNASAYRMHPAVPIIIPEVNQDHLQLVDKQPFSGKIITNSNCCVSGIALALAPLGEFGIDR
VNIVTLQSASGAGYPGVSSMDVLGNTVPHIVGEEEKILRETLKILGKCEEPADFPITVTVHRVPVVYGHTLTLHVTFLDA
VDIKDILYSYHCRNSEFPETYKLYDSPWHPQARKDLTDEDMRVHIGPITYGGDARTIKMNVLVHNLVRGAAGTLLKNMHN
YCFQNSGEYACSQ

Specific function: This enzyme catalyzes the second step in the common metabolic pathway to synthesize Thr and Met from Asp [H]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320362, Length=346, Percent_Identity=33.8150289017341, Blast_Score=143, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR005676
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36805; Mature: 36805

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAVLGATGLVGQKFIALLHKWFPWQICEVVASATKYSQTYGSACMWQEALGPMPESMV
CEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHH
RVPIRKIEEIESDIIASFLPEPVAESLETYCLSQGKLVFSNASAYRMHPAVPIIIPEVNQ
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCEEEECCCCEEEECCCCC
DHLQLVDKQPFSGKIITNSNCCVSGIALALAPLGEFGIDRVNIVTLQSASGAGYPGVSSM
HHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCH
DVLGNTVPHIVGEEEKILRETLKILGKCEEPADFPITVTVHRVPVVYGHTLTLHVTFLDA
HHHCCCCCHHCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCEEEEEEEEECH
VDIKDILYSYHCRNSEFPETYKLYDSPWHPQARKDLTDEDMRVHIGPITYGGDARTIKMN
HHHHHHHHHHHCCCCCCCCHHCCCCCCCCCHHHCCCCCCCCEEEEEEEEECCCCEEEEHH
VLVHNLVRGAAGTLLKNMHNYCFQNSGEYACSQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRVAVLGATGLVGQKFIALLHKWFPWQICEVVASATKYSQTYGSACMWQEALGPMPESMV
CEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHH
RVPIRKIEEIESDIIASFLPEPVAESLETYCLSQGKLVFSNASAYRMHPAVPIIIPEVNQ
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCEEEECCCCEEEECCCCC
DHLQLVDKQPFSGKIITNSNCCVSGIALALAPLGEFGIDRVNIVTLQSASGAGYPGVSSM
HHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCH
DVLGNTVPHIVGEEEKILRETLKILGKCEEPADFPITVTVHRVPVVYGHTLTLHVTFLDA
HHHCCCCCHHCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCEEEEEEEEECH
VDIKDILYSYHCRNSEFPETYKLYDSPWHPQARKDLTDEDMRVHIGPITYGGDARTIKMN
HHHHHHHHHHHCCCCCCCCHHCCCCCCCCCHHHCCCCCCCCEEEEEEEEECCCCEEEEHH
VLVHNLVRGAAGTLLKNMHNYCFQNSGEYACSQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]