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The map label for this gene is dapB

Identifier: 89898110

GI number: 89898110

Start: 350651

End: 351391

Strand: Direct

Name: dapB

Synonym: CF0303

Alternate gene names: 89898110

Gene position: 350651-351391 (Clockwise)

Preceding gene: 89898090

Following gene: 89898111

Centisome position: 30.07

GC content: 42.91

Gene sequence:

>741_bases
ATGCGTGTTGGTATTGTCGGATGTTCGGGAAGAATGGGAACACTGCTTAGTGTTTTGTTAAGCTCAACGACTCGCTTTAC
TCTGGGACCAGGATATTCTAGAAAAGGTGCTCATTCTTTAGCCTCTGTCATAGAAAATAATGATGTTCTTGTGGATTTTT
CTTCTTCCTCTTTTTCCGAAGAACTTCTTTCTGCTTTGCTCTCTAATCCCAAACCTTTGATTTTCGCAACGACTAAGCCC
ATAGCATCTTGCTCCATAGATGAGAAATTAGAACGTCTGGCTGTGCACGTCCCGGTTGTTGTCTGTCCGAACACAAGTCT
GGGAGCTTATGTGCAAAAACGTTTAGCTGCTCTGCTTGCTAGAGTTTTTGATGATACGTACGATATCCGTGTCGCAGAAG
TACATCATCGGCACAAGAGAGATCCTATTTCTGGAACAGCCAATGAATTGGTCTCAGTGCTTTGTGATGCTAAGCAAAAG
GAATGGAATCAGGAATACAGTGTGGGGACTAACTGTAATAATGTGAAAAACATCGAATTACATGCCTCGCGTGTAGGGAA
TGTTTCGGGTGAACACGAAGTAGCCTTTATCAGTGATAAAGAGCAAATCGTTTTAAAGCACACAGTCTTTTCTCGAGAGG
TTTTTGCAGAAGGAACTTTGAGGATTTTAGACTGGTTAATAGATAGCTCTCCACCTCCCGGATACTACGGTCCTGAAGTC
GGGCTAAAGGTTTCTGTGTGA

Upstream 100 bases:

>100_bases
GAGATTTTAATTCTAAGGTCCTTTAGGGTTTTTGTCGAGGGAAAGCTAATCTTCCCACAGAGATGAAAACAGTAGGTTTT
TTTAATTTTAAGAAGGATTT

Downstream 100 bases:

>100_bases
GTGAACAGTTCTTGCTTAAAAAACAAAACGGTTATTACAATGCGGCCTCTAAGATTCTTTGATTTTTGAATAAAAGGAGA
GCGTGTTTTGCATTATCAAC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MRVGIVGCSGRMGTLLSVLLSSTTRFTLGPGYSRKGAHSLASVIENNDVLVDFSSSSFSEELLSALLSNPKPLIFATTKP
IASCSIDEKLERLAVHVPVVVCPNTSLGAYVQKRLAALLARVFDDTYDIRVAEVHHRHKRDPISGTANELVSVLCDAKQK
EWNQEYSVGTNCNNVKNIELHASRVGNVSGEHEVAFISDKEQIVLKHTVFSREVFAEGTLRILDWLIDSSPPPGYYGPEV
GLKVSV

Sequences:

>Translated_246_residues
MRVGIVGCSGRMGTLLSVLLSSTTRFTLGPGYSRKGAHSLASVIENNDVLVDFSSSSFSEELLSALLSNPKPLIFATTKP
IASCSIDEKLERLAVHVPVVVCPNTSLGAYVQKRLAALLARVFDDTYDIRVAEVHHRHKRDPISGTANELVSVLCDAKQK
EWNQEYSVGTNCNNVKNIELHASRVGNVSGEHEVAFISDKEQIVLKHTVFSREVFAEGTLRILDWLIDSSPPPGYYGPEV
GLKVSV
>Mature_246_residues
MRVGIVGCSGRMGTLLSVLLSSTTRFTLGPGYSRKGAHSLASVIENNDVLVDFSSSSFSEELLSALLSNPKPLIFATTKP
IASCSIDEKLERLAVHVPVVVCPNTSLGAYVQKRLAALLARVFDDTYDIRVAEVHHRHKRDPISGTANELVSVLCDAKQK
EWNQEYSVGTNCNNVKNIELHASRVGNVSGEHEVAFISDKEQIVLKHTVFSREVFAEGTLRILDWLIDSSPPPGYYGPEV
GLKVSV

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=267, Percent_Identity=26.5917602996255, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_CHLFF (Q255G3)

Other databases:

- EMBL:   AP006861
- RefSeq:   YP_515220.1
- ProteinModelPortal:   Q255G3
- SMR:   Q255G3
- STRING:   Q255G3
- GeneID:   3958684
- GenomeReviews:   AP006861_GR
- KEGG:   cfe:CF0303
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   KQKPGFY
- ProtClustDB:   PRK00048
- BioCyc:   CFEL264202:CF0303-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 26849; Mature: 26849

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVGIVGCSGRMGTLLSVLLSSTTRFTLGPGYSRKGAHSLASVIENNDVLVDFSSSSFSE
CEEEEEECCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCHHH
ELLSALLSNPKPLIFATTKPIASCSIDEKLERLAVHVPVVVCPNTSLGAYVQKRLAALLA
HHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHH
RVFDDTYDIRVAEVHHRHKRDPISGTANELVSVLCDAKQKEWNQEYSVGTNCNNVKNIEL
HHHCCCCCEEHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHCCCCCCCCCCCCCCEEEEE
HASRVGNVSGEHEVAFISDKEQIVLKHTVFSREVFAEGTLRILDWLIDSSPPPGYYGPEV
EHHHCCCCCCCCEEEEECCCCEEEEEHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCC
GLKVSV
CEEECC
>Mature Secondary Structure
MRVGIVGCSGRMGTLLSVLLSSTTRFTLGPGYSRKGAHSLASVIENNDVLVDFSSSSFSE
CEEEEEECCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCHHH
ELLSALLSNPKPLIFATTKPIASCSIDEKLERLAVHVPVVVCPNTSLGAYVQKRLAALLA
HHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHH
RVFDDTYDIRVAEVHHRHKRDPISGTANELVSVLCDAKQKEWNQEYSVGTNCNNVKNIEL
HHHCCCCCEEHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHCCCCCCCCCCCCCCEEEEE
HASRVGNVSGEHEVAFISDKEQIVLKHTVFSREVFAEGTLRILDWLIDSSPPPGYYGPEV
EHHHCCCCCCCCEEEEECCCCEEEEEHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCC
GLKVSV
CEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA