Click here to switch to the map view.

The map label for this gene is mraY

Identifier: 89897955

GI number: 89897955

Start: 179691

End: 180737

Strand: Direct

Name: mraY

Synonym: CF0148

Alternate gene names: 89897955

Gene position: 179691-180737 (Clockwise)

Preceding gene: 89897954

Following gene: 89897956

Centisome position: 15.41

GC content: 38.97

Gene sequence:

>1047_bases
ATGCATTCTGTGTTTTCTTATCTTAATGAATCTTTGATTCTTTTTCTGGTAACTGTAATGGGATTTGCTTTTCTCGTTGG
AATTTTCTTGGGAAAACCCGTGATACACTGGCTGAAGAAACAAAATTACTATGATCAAGTGCAAAAGGAACACTGTGCAA
AGCTAGAAACCCTTCATAAAGATAAGAAATATACGCCTACAGCTGGCGGCGTACTCTTTTTTCTCGTTTTACTGATGTCT
ATTTTCTTTTTACTACCTCTAAGGAAACCTTCCACATGGTTATTTGTATTCTCCATAGTTAGTTGGGGTTCCCTGGGGTG
GTATGACGATATAGTGAAAAAGAAAAGAAAGAAAGGGCATGGAATAACCGCAAAGCAGAAATTTATTGTACAGTTGTTAC
TGTCAGCAGTTACTGTTATAACCGTGTTCTTTATAGATAAAGAGAACTCCTTGTTTTGCACTTTACAAGTTCCTTTTTTC
AGAACCATTTTTTTGGGATCTTCTATTTTAGCAAAGCTTTTTTGTTTTTCTTTGGCAATGTTAGCAATTATAGGCACCAG
CAATGCTGTCAATCTTACAGACGGTCTTGATGGCTTGGCTACAGGCATTACATGTATGAGTTCGTTCGGTTTGTTAATAG
TTGCTATTATGAGTCCTACCAATCCTCTAGCTTATGATGTTTCTATAGTGTTGGCAACATTGGTAGGGATAAGCTTGGCT
TTCCTAAGGTATAATTGTTCTCCTGCCCAAGTGTTCATGGGGGATACAGGTTCTTTGCTCATAGGAGGCATATTGGCCAG
TTGTGCTGTTATGCTCCGTGCAGAATTGTTTCTGATTTTCTTAGGCGGAGTGTTCGTTGCAGAAGCAGGATCTGTAATCC
TGCAAGTTGCTAGTTGCCGATTACGGAAAAAACGCATTTTTCTTTGTTCCCCACTGCATCATCATTATGAGTATAAAGGC
ATACCAGAAACTCAGGTTGTCGCACGTTTTTGGATGGCAGGATTACTTTGTACAGTTTTAGGAATAGTCGCAGCTTTGTG
GAGATAG

Upstream 100 bases:

>100_bases
AGAGTGTCGTTCAGCAAGGAGATATTGTCTTGCTGAAGGGATCGAGAGCTTTGGCTTTAGAGTCTCTGTTGAGCTGTTTT
TAATTTTTAATACTTTACTT

Downstream 100 bases:

>100_bases
TTTGTGAATCATCAACGTGTCGTAGTTTTAGGTGCTGGTGTTACAGGAAAATCTGCAGCAGAGTTTCTTCATAAAAAAGG
AGATTTTGTTATCGGAATTG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MHSVFSYLNESLILFLVTVMGFAFLVGIFLGKPVIHWLKKQNYYDQVQKEHCAKLETLHKDKKYTPTAGGVLFFLVLLMS
IFFLLPLRKPSTWLFVFSIVSWGSLGWYDDIVKKKRKKGHGITAKQKFIVQLLLSAVTVITVFFIDKENSLFCTLQVPFF
RTIFLGSSILAKLFCFSLAMLAIIGTSNAVNLTDGLDGLATGITCMSSFGLLIVAIMSPTNPLAYDVSIVLATLVGISLA
FLRYNCSPAQVFMGDTGSLLIGGILASCAVMLRAELFLIFLGGVFVAEAGSVILQVASCRLRKKRIFLCSPLHHHYEYKG
IPETQVVARFWMAGLLCTVLGIVAALWR

Sequences:

>Translated_348_residues
MHSVFSYLNESLILFLVTVMGFAFLVGIFLGKPVIHWLKKQNYYDQVQKEHCAKLETLHKDKKYTPTAGGVLFFLVLLMS
IFFLLPLRKPSTWLFVFSIVSWGSLGWYDDIVKKKRKKGHGITAKQKFIVQLLLSAVTVITVFFIDKENSLFCTLQVPFF
RTIFLGSSILAKLFCFSLAMLAIIGTSNAVNLTDGLDGLATGITCMSSFGLLIVAIMSPTNPLAYDVSIVLATLVGISLA
FLRYNCSPAQVFMGDTGSLLIGGILASCAVMLRAELFLIFLGGVFVAEAGSVILQVASCRLRKKRIFLCSPLHHHYEYKG
IPETQVVARFWMAGLLCTVLGIVAALWR
>Mature_348_residues
MHSVFSYLNESLILFLVTVMGFAFLVGIFLGKPVIHWLKKQNYYDQVQKEHCAKLETLHKDKKYTPTAGGVLFFLVLLMS
IFFLLPLRKPSTWLFVFSIVSWGSLGWYDDIVKKKRKKGHGITAKQKFIVQLLLSAVTVITVFFIDKENSLFCTLQVPFF
RTIFLGSSILAKLFCFSLAMLAIIGTSNAVNLTDGLDGLATGITCMSSFGLLIVAIMSPTNPLAYDVSIVLATLVGISLA
FLRYNCSPAQVFMGDTGSLLIGGILASCAVMLRAELFLIFLGGVFVAEAGSVILQVASCRLRKKRIFLCSPLHHHYEYKG
IPETQVVARFWMAGLLCTVLGIVAALWR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=353, Percent_Identity=37.3937677053824, Blast_Score=199, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_CHLFF (Q255W8)

Other databases:

- EMBL:   AP006861
- RefSeq:   YP_515065.1
- STRING:   Q255W8
- GeneID:   3958952
- GenomeReviews:   AP006861_GR
- KEGG:   cfe:CF0148
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   CFEL264202:CF0148-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 38548; Mature: 38548

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1f11458c)-; HASH(0x211239f4)-; HASH(0x210f3370)-; HASH(0x210ca1c4)-; HASH(0x2114f5dc)-; HASH(0x210d6430)-; HASH(0x210ca47c)-; HASH(0x210f33f4)-; HASH(0x203505a4)-; HASH(0x20cc0bc4)-;

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure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HHHHHEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA