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The map label for this gene is rodA [H]

Identifier: 89897921

GI number: 89897921

Start: 130443

End: 131582

Strand: Direct

Name: rodA [H]

Synonym: CF0114

Alternate gene names: 89897921

Gene position: 130443-131582 (Clockwise)

Preceding gene: 89897919

Following gene: 89897925

Centisome position: 11.18

GC content: 39.04

Gene sequence:

>1140_bases
ATGAGAAACACTAGATATTTCAGCTATGTCAATTACTGGGTGTTTGTTGTCATTATTGTATTAATGATGATTAGCATAGT
TGTAATTTCTTCTATGGACCCATCAACGATACTCGTAACCTCATCAAAGGGCTTGCTGACGAATAAAAGTATCATGCAAC
TTCGCCATTTTGCTTTGGGATGGACGGTTTTTTTCGTTTGTATGTGGCTCGATTACCATAAGCTAAGAAGTTGGGCGTGG
GTTCTTTACATTCTTATGATTTTGAGCCTTGCAGGATTGTTTTTTGTCCCCACAGTGCAAAATGTTCATCGATGGTATAA
AATTCCCTTCATTGGTTTAAGTGTTCAGCCGTCTGAATATGCTAAGCTTATTGTCGTGATTATGCTCAGCTACATGTTAG
ATATACGCAAATCTGAAATCTCTTCAAAGACGACAGCTTTCATAGCCTGTGTTATTGTCGGTATTCCCTTTTTCCTTATT
TTTAAAGAACCGGATTTAGGCACAGCTTTAGTTTTATGCCCCGTTGCTTTGGTGATTTTTTATTTGGGGAATATTCACCC
CTTGTTTGTGAAAATCTGTGCAACCTTTGCAGGAATTGGTCTTCTTTGCTCCCTATTGATTTTTTCTGGAATGATTTCTC
ATGAAACAGTAAAGCCTTACGCATTAAAGGTGATCAAGGAATATCAGTATGAAAGATTAAGCCCTTCAAATCATCATCAG
CGAGCATCATTAATTTCCATTGGATTAGGAGGAGTTAAGGGACGCGGGTGGAAATCGGGAGAATTTGCTGGAAGAGGCTG
GCTTCCCTATGGATATACGGACTCGGTATTTCCAGCTTTAGGAGAGGAATTTGGATTGGTTGGTCTTTTTTTCGCTTTGT
GGATGTTTTACTGTTTAATTTGTTTCGGCTGTAGAACGGTGGCTGTTGCCGTTGATGATTTTGGCCGATTATTAGCTGCA
GGAATCACAGTACATATCTCTATGCATGTTATAATCAATATTAGCATGATGTGTGGATTGATGCCTATTACCGGAGTGCC
CTTGGTTTTGGTTTCCTATGGTGGATCTTCAGTTATTTCCACGATGGCGTCATTAGGAATCTTACAAAGTATCTACAGTC
GTAGATTCTCAAAATACTAA

Upstream 100 bases:

>100_bases
TGAGTTGTTTTGCTGTAGCGTTGGTAGATGGAGTTTCTGCTATTTCGTAGTAAATAACTTTCATTGGAAGTATCCCCACT
CTTAATTTATAAAGAGCATT

Downstream 100 bases:

>100_bases
GATTATTTCAGTAACCGTAAAGCGTTGAGCCCTACAATAATCGTACTACCCTCATGGAGAATCACTGCCAGCCATAGGGG
AATAATCCCTAAAGAAGCAG

Product: cell division related rod shape-determining membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MRNTRYFSYVNYWVFVVIIVLMMISIVVISSMDPSTILVTSSKGLLTNKSIMQLRHFALGWTVFFVCMWLDYHKLRSWAW
VLYILMILSLAGLFFVPTVQNVHRWYKIPFIGLSVQPSEYAKLIVVIMLSYMLDIRKSEISSKTTAFIACVIVGIPFFLI
FKEPDLGTALVLCPVALVIFYLGNIHPLFVKICATFAGIGLLCSLLIFSGMISHETVKPYALKVIKEYQYERLSPSNHHQ
RASLISIGLGGVKGRGWKSGEFAGRGWLPYGYTDSVFPALGEEFGLVGLFFALWMFYCLICFGCRTVAVAVDDFGRLLAA
GITVHISMHVIINISMMCGLMPITGVPLVLVSYGGSSVISTMASLGILQSIYSRRFSKY

Sequences:

>Translated_379_residues
MRNTRYFSYVNYWVFVVIIVLMMISIVVISSMDPSTILVTSSKGLLTNKSIMQLRHFALGWTVFFVCMWLDYHKLRSWAW
VLYILMILSLAGLFFVPTVQNVHRWYKIPFIGLSVQPSEYAKLIVVIMLSYMLDIRKSEISSKTTAFIACVIVGIPFFLI
FKEPDLGTALVLCPVALVIFYLGNIHPLFVKICATFAGIGLLCSLLIFSGMISHETVKPYALKVIKEYQYERLSPSNHHQ
RASLISIGLGGVKGRGWKSGEFAGRGWLPYGYTDSVFPALGEEFGLVGLFFALWMFYCLICFGCRTVAVAVDDFGRLLAA
GITVHISMHVIINISMMCGLMPITGVPLVLVSYGGSSVISTMASLGILQSIYSRRFSKY
>Mature_379_residues
MRNTRYFSYVNYWVFVVIIVLMMISIVVISSMDPSTILVTSSKGLLTNKSIMQLRHFALGWTVFFVCMWLDYHKLRSWAW
VLYILMILSLAGLFFVPTVQNVHRWYKIPFIGLSVQPSEYAKLIVVIMLSYMLDIRKSEISSKTTAFIACVIVGIPFFLI
FKEPDLGTALVLCPVALVIFYLGNIHPLFVKICATFAGIGLLCSLLIFSGMISHETVKPYALKVIKEYQYERLSPSNHHQ
RASLISIGLGGVKGRGWKSGEFAGRGWLPYGYTDSVFPALGEEFGLVGLFFALWMFYCLICFGCRTVAVAVDDFGRLLAA
GITVHISMHVIINISMMCGLMPITGVPLVLVSYGGSSVISTMASLGILQSIYSRRFSKY

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=342, Percent_Identity=29.8245614035088, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786277, Length=289, Percent_Identity=27.3356401384083, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 42435; Mature: 42435

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNTRYFSYVNYWVFVVIIVLMMISIVVISSMDPSTILVTSSKGLLTNKSIMQLRHFALG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
WTVFFVCMWLDYHKLRSWAWVLYILMILSLAGLFFVPTVQNVHRWYKIPFIGLSVQPSEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCHHHH
AKLIVVIMLSYMLDIRKSEISSKTTAFIACVIVGIPFFLIFKEPDLGTALVLCPVALVIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHH
YLGNIHPLFVKICATFAGIGLLCSLLIFSGMISHETVKPYALKVIKEYQYERLSPSNHHQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHH
RASLISIGLGGVKGRGWKSGEFAGRGWLPYGYTDSVFPALGEEFGLVGLFFALWMFYCLI
HHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
CFGCRTVAVAVDDFGRLLAAGITVHISMHVIINISMMCGLMPITGVPLVLVSYGGSSVIS
HHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHH
TMASLGILQSIYSRRFSKY
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRNTRYFSYVNYWVFVVIIVLMMISIVVISSMDPSTILVTSSKGLLTNKSIMQLRHFALG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
WTVFFVCMWLDYHKLRSWAWVLYILMILSLAGLFFVPTVQNVHRWYKIPFIGLSVQPSEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCHHHH
AKLIVVIMLSYMLDIRKSEISSKTTAFIACVIVGIPFFLIFKEPDLGTALVLCPVALVIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHH
YLGNIHPLFVKICATFAGIGLLCSLLIFSGMISHETVKPYALKVIKEYQYERLSPSNHHQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHH
RASLISIGLGGVKGRGWKSGEFAGRGWLPYGYTDSVFPALGEEFGLVGLFFALWMFYCLI
HHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
CFGCRTVAVAVDDFGRLLAAGITVHISMHVIINISMMCGLMPITGVPLVLVSYGGSSVIS
HHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHH
TMASLGILQSIYSRRFSKY
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]