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The map label for this gene is glnII [H]

Identifier: 89257147

GI number: 89257147

Start: 1829684

End: 1830721

Strand: Direct

Name: glnII [H]

Synonym: FTL_1899

Alternate gene names: 89257147

Gene position: 1829684-1830721 (Clockwise)

Preceding gene: 89257146

Following gene: 89257148

Centisome position: 96.5

GC content: 38.34

Gene sequence:

>1038_bases
ATGAAAGTAATAACCGCTGAATACATATGGGCTGATGGTTCAGATCCTGTGCCTCATCTTAGATCTAAAGCAAGAGTTTT
ACCATTTAAAGAATTTGAAACTCCAGATGAATTTCCAGAATGGAGTTTTGATGGTTCTTCAACAAACCAAGCTACAGGAG
ATAACTCAGATTGTATTCTTAAACCTGTTAACTTTGTAATTGATCCACTAAGAGATTATGGTTACTTAGTATTATGTGAA
GTTTATAATCCAGATGGACAAACTCCGCATGCGACAAATAATCGTGCCAAGCTAAGAGCTCTATTAGCTAGTGCTGACTG
CCAAGATATGTGGGCAGGTTTCGAACAAGAGTATACAATGTTCAAAGATGGTAGACCACTTGGATGGCCTACTACAGGAT
TTCCTGGTCCACAAGGTCCTTATTATTGTAGTGCTGGTAATAGCAAAGCTTTTGGTCGTGACTTAGTTGAGGCTCATATG
CAGGCGTGTCTAGAGGCGGGAATTTTATTCTATGGTATAAATGCTGAAGTTATGCCAGGGCAATGGGAATTTCAAATTGG
CTATAGAGGTGTTGATGGTGAGGACGCTGGTATATTAAATGTTGCAGACCATACTCACCTTGCTAGATGGCTACTAGAGA
GACTTGGTGAAGAATATGGTATTGATATATCTTTTGATAACAAACCTATCAAAGGCGACTGGAATGGTGCTGGTCTTCAT
ACTAACTTCTCTACGAGTAAAACTAGAAATCCTCAAACAGGTAGAGAAGCTATTAAGAAGATATGTGCAGCATTAGAAAA
AAATCATAAAAAAGATATCTTAAACTATGGTCACAATCTTCATGAGAGATTAACAGGTAAACTAGAAACTTCTGATATGA
ATACTTTCAGTGTTGGAGATGCTGATAGAGGATGTTCTATTAGAATCCCAAGACCTGTTGCACTTAAGGGCTATGGCTAC
CTTGAAGATAGAAGACCTGGCGCAAATGCTGATCCTTATGTTATTGCTATGGCTTTAGCTAATGCTGCTATAAACTAA

Upstream 100 bases:

>100_bases
TGCTAAATTTTAATGACAACTGTAATAGTAGCATTTACTTTTTTTAGACAATTGATATCATTAAACAGAATTAACCAATG
TTAAGGAATATAGTGAAGAT

Downstream 100 bases:

>100_bases
CTATATTGTCTATATATCAAATCTTTGTTTTTTTCGGTAAAATAACTCAATATTATTTTTTATAAAACCATATTTCTTTA
AATGAAAACAATAATGATTA

Product: glutamine synthetase

Products: NA

Alternate protein names: Glutamate--ammonia ligase II; Glutamine synthetase II; GSII [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKVITAEYIWADGSDPVPHLRSKARVLPFKEFETPDEFPEWSFDGSSTNQATGDNSDCILKPVNFVIDPLRDYGYLVLCE
VYNPDGQTPHATNNRAKLRALLASADCQDMWAGFEQEYTMFKDGRPLGWPTTGFPGPQGPYYCSAGNSKAFGRDLVEAHM
QACLEAGILFYGINAEVMPGQWEFQIGYRGVDGEDAGILNVADHTHLARWLLERLGEEYGIDISFDNKPIKGDWNGAGLH
TNFSTSKTRNPQTGREAIKKICAALEKNHKKDILNYGHNLHERLTGKLETSDMNTFSVGDADRGCSIRIPRPVALKGYGY
LEDRRPGANADPYVIAMALANAAIN

Sequences:

>Translated_345_residues
MKVITAEYIWADGSDPVPHLRSKARVLPFKEFETPDEFPEWSFDGSSTNQATGDNSDCILKPVNFVIDPLRDYGYLVLCE
VYNPDGQTPHATNNRAKLRALLASADCQDMWAGFEQEYTMFKDGRPLGWPTTGFPGPQGPYYCSAGNSKAFGRDLVEAHM
QACLEAGILFYGINAEVMPGQWEFQIGYRGVDGEDAGILNVADHTHLARWLLERLGEEYGIDISFDNKPIKGDWNGAGLH
TNFSTSKTRNPQTGREAIKKICAALEKNHKKDILNYGHNLHERLTGKLETSDMNTFSVGDADRGCSIRIPRPVALKGYGY
LEDRRPGANADPYVIAMALANAAIN
>Mature_345_residues
MKVITAEYIWADGSDPVPHLRSKARVLPFKEFETPDEFPEWSFDGSSTNQATGDNSDCILKPVNFVIDPLRDYGYLVLCE
VYNPDGQTPHATNNRAKLRALLASADCQDMWAGFEQEYTMFKDGRPLGWPTTGFPGPQGPYYCSAGNSKAFGRDLVEAHM
QACLEAGILFYGINAEVMPGQWEFQIGYRGVDGEDAGILNVADHTHLARWLLERLGEEYGIDISFDNKPIKGDWNGAGLH
TNFSTSKTRNPQTGREAIKKICAALEKNHKKDILNYGHNLHERLTGKLETSDMNTFSVGDADRGCSIRIPRPVALKGYGY
LEDRRPGANADPYVIAMALANAAIN

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI74271826, Length=347, Percent_Identity=47.2622478386167, Blast_Score=294, Evalue=8e-80,
Organism=Homo sapiens, GI74271837, Length=347, Percent_Identity=47.2622478386167, Blast_Score=294, Evalue=8e-80,
Organism=Homo sapiens, GI19923206, Length=347, Percent_Identity=47.2622478386167, Blast_Score=294, Evalue=8e-80,
Organism=Caenorhabditis elegans, GI115532978, Length=344, Percent_Identity=49.7093023255814, Blast_Score=311, Evalue=4e-85,
Organism=Caenorhabditis elegans, GI115532980, Length=344, Percent_Identity=49.7093023255814, Blast_Score=310, Evalue=5e-85,
Organism=Caenorhabditis elegans, GI17538856, Length=349, Percent_Identity=46.7048710601719, Blast_Score=285, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17540008, Length=347, Percent_Identity=45.5331412103746, Blast_Score=283, Evalue=7e-77,
Organism=Caenorhabditis elegans, GI17554028, Length=349, Percent_Identity=44.9856733524355, Blast_Score=273, Evalue=7e-74,
Organism=Caenorhabditis elegans, GI17551038, Length=312, Percent_Identity=40.3846153846154, Blast_Score=227, Evalue=8e-60,
Organism=Saccharomyces cerevisiae, GI6325292, Length=335, Percent_Identity=49.8507462686567, Blast_Score=312, Evalue=5e-86,
Organism=Drosophila melanogaster, GI281360453, Length=348, Percent_Identity=46.551724137931, Blast_Score=307, Evalue=7e-84,
Organism=Drosophila melanogaster, GI17136208, Length=348, Percent_Identity=46.551724137931, Blast_Score=307, Evalue=7e-84,
Organism=Drosophila melanogaster, GI24580558, Length=348, Percent_Identity=46.551724137931, Blast_Score=307, Evalue=7e-84,
Organism=Drosophila melanogaster, GI24641290, Length=343, Percent_Identity=48.3965014577259, Blast_Score=298, Evalue=3e-81,
Organism=Drosophila melanogaster, GI24641292, Length=343, Percent_Identity=48.3965014577259, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI45554830, Length=267, Percent_Identity=49.812734082397, Blast_Score=247, Evalue=7e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 38257; Mature: 38257

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVITAEYIWADGSDPVPHLRSKARVLPFKEFETPDEFPEWSFDGSSTNQATGDNSDCIL
CCEEEEEEEECCCCCCCHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
KPVNFVIDPLRDYGYLVLCEVYNPDGQTPHATNNRAKLRALLASADCQDMWAGFEQEYTM
ECHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCHHHHHHH
FKDGRPLGWPTTGFPGPQGPYYCSAGNSKAFGRDLVEAHMQACLEAGILFYGINAEVMPG
HCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCEECCC
QWEFQIGYRGVDGEDAGILNVADHTHLARWLLERLGEEYGIDISFDNKPIKGDWNGAGLH
CEEEEEEEECCCCCCCCEEEEHHHHHHHHHHHHHCCHHHCEEEEECCCCCCCCCCCCCEE
TNFSTSKTRNPQTGREAIKKICAALEKNHKKDILNYGHNLHERLTGKLETSDMNTFSVGD
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHCCCEECCCCCEEECCC
ADRGCSIRIPRPVALKGYGYLEDRRPGANADPYVIAMALANAAIN
CCCCCEEECCCCEEEECCCCCCCCCCCCCCCCCEEEEEHHHHHCC
>Mature Secondary Structure
MKVITAEYIWADGSDPVPHLRSKARVLPFKEFETPDEFPEWSFDGSSTNQATGDNSDCIL
CCEEEEEEEECCCCCCCHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
KPVNFVIDPLRDYGYLVLCEVYNPDGQTPHATNNRAKLRALLASADCQDMWAGFEQEYTM
ECHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCHHHHHHH
FKDGRPLGWPTTGFPGPQGPYYCSAGNSKAFGRDLVEAHMQACLEAGILFYGINAEVMPG
HCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCEECCC
QWEFQIGYRGVDGEDAGILNVADHTHLARWLLERLGEEYGIDISFDNKPIKGDWNGAGLH
CEEEEEEEECCCCCCCCEEEEHHHHHHHHHHHHHCCHHHCEEEEECCCCCCCCCCCCCEE
TNFSTSKTRNPQTGREAIKKICAALEKNHKKDILNYGHNLHERLTGKLETSDMNTFSVGD
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHCCCEECCCCCEEECCC
ADRGCSIRIPRPVALKGYGYLEDRRPGANADPYVIAMALANAAIN
CCCCCEEECCCCEEEECCCCCCCCCCCCCCCCCEEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1975583 [H]