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The map label for this gene is trxB [H]

Identifier: 89256848

GI number: 89256848

Start: 1499219

End: 1500169

Strand: Direct

Name: trxB [H]

Synonym: FTL_1571

Alternate gene names: 89256848

Gene position: 1499219-1500169 (Clockwise)

Preceding gene: 89256847

Following gene: 89256849

Centisome position: 79.07

GC content: 36.8

Gene sequence:

>951_bases
ATGGCAAATCATCATAAACTAATAATTTTAGGATCTGGGCCTGCTGGCTATACTGCAGCAATATATGCAGCACGTGCAAA
CTTAAAGCCAGTAATTATCACTGGTATGCAACCAGGAGGTCAACTTACGACTACTACCGATGTAGATAACTGGCCTGGTG
AGCCTGATGGTATCATAGGTCCTGAGCTTATGGAAAAACTACAAAAACAAGCAGAAAGATTCGATACACAAATAGTCTAT
GACACTATCAATGCTGTAGATTTACAAAATAAACCTTTTAAACTAGTTGGTGAAGTTGAGCAATATACATGTGATACTCT
AATTATAGCAACTGGTGCTACTGCTAAATATCTAGGTTTAGAGTCAGAAGAGAAGTTTATGGGTAAAGGTGTCTCTGCTT
GTGCTACTTGTGATGGCTTCTTTTACAAAAATAAAGACGTTGCAGTAGTTGGTGGTGGCAACACTGCTGTTGAAGAAGCA
TTATTTTTATCCAATATTGCTAAATCTGTAACTTTAATCCACCGTAGAGATACATTAAGGTCTGAAAAAATTCTTATCGA
CAAGCTAATGGAAAAAGCTCAACATGGTAATATAAATATCATTTGGAACACTACTTTAGAAGAAGTTCTTGGCGATGATA
TGGGAGTTAATGCTCTGCGTATCAAAAATATCAAAACTAATGAAGAGTCTCAAATTGATGTCGCTGGTGTTTTTATTGCT
ATTGGCCATACACCAAATACTAGTATTTTTGCTGGTCAGCTTGAAATGGAAAATGGCTATATTAAGGTGAAATCAGGTCT
AGCTGGCGATGCTACTCAAACAAATATCAAAGGGGTATTTGCAGCTGGTGATGTAGCTGATCATGTTTATAAACAAGCAG
TAACATCTGCAGGTACTGGCTGTATGGCTGCACTAGATGCTGAGAAGTATTTAGATAATTTAGATCAATAA

Upstream 100 bases:

>100_bases
TGTACCTAATATATACTATATAAACGTATTGAAAGTTTACTTAAATTAGCACTATGCTATAATTTGCTCTACATATTTAT
TCAAAAATTTTTTAAAAAAA

Downstream 100 bases:

>100_bases
AATATAAACCCTCACTTAATAAATTAAATATTAGCCATAATATAATTTTCAATTAGGTTCTGTGCACAAAAAACTTAAAT
TATATTGAAAATAGCTAAAC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MANHHKLIILGSGPAGYTAAIYAARANLKPVIITGMQPGGQLTTTTDVDNWPGEPDGIIGPELMEKLQKQAERFDTQIVY
DTINAVDLQNKPFKLVGEVEQYTCDTLIIATGATAKYLGLESEEKFMGKGVSACATCDGFFYKNKDVAVVGGGNTAVEEA
LFLSNIAKSVTLIHRRDTLRSEKILIDKLMEKAQHGNINIIWNTTLEEVLGDDMGVNALRIKNIKTNEESQIDVAGVFIA
IGHTPNTSIFAGQLEMENGYIKVKSGLAGDATQTNIKGVFAAGDVADHVYKQAVTSAGTGCMAALDAEKYLDNLDQ

Sequences:

>Translated_316_residues
MANHHKLIILGSGPAGYTAAIYAARANLKPVIITGMQPGGQLTTTTDVDNWPGEPDGIIGPELMEKLQKQAERFDTQIVY
DTINAVDLQNKPFKLVGEVEQYTCDTLIIATGATAKYLGLESEEKFMGKGVSACATCDGFFYKNKDVAVVGGGNTAVEEA
LFLSNIAKSVTLIHRRDTLRSEKILIDKLMEKAQHGNINIIWNTTLEEVLGDDMGVNALRIKNIKTNEESQIDVAGVFIA
IGHTPNTSIFAGQLEMENGYIKVKSGLAGDATQTNIKGVFAAGDVADHVYKQAVTSAGTGCMAALDAEKYLDNLDQ
>Mature_315_residues
ANHHKLIILGSGPAGYTAAIYAARANLKPVIITGMQPGGQLTTTTDVDNWPGEPDGIIGPELMEKLQKQAERFDTQIVYD
TINAVDLQNKPFKLVGEVEQYTCDTLIIATGATAKYLGLESEEKFMGKGVSACATCDGFFYKNKDVAVVGGGNTAVEEAL
FLSNIAKSVTLIHRRDTLRSEKILIDKLMEKAQHGNINIIWNTTLEEVLGDDMGVNALRIKNIKTNEESQIDVAGVFIAI
GHTPNTSIFAGQLEMENGYIKVKSGLAGDATQTNIKGVFAAGDVADHVYKQAVTSAGTGCMAALDAEKYLDNLDQ

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=312, Percent_Identity=67.948717948718, Blast_Score=462, Evalue=1e-131,
Organism=Escherichia coli, GI87081763, Length=300, Percent_Identity=33, Blast_Score=143, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320560, Length=324, Percent_Identity=50.3086419753086, Blast_Score=309, Evalue=4e-85,
Organism=Saccharomyces cerevisiae, GI6321898, Length=321, Percent_Identity=48.5981308411215, Blast_Score=298, Evalue=9e-82,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33972; Mature: 33841

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANHHKLIILGSGPAGYTAAIYAARANLKPVIITGMQPGGQLTTTTDVDNWPGEPDGIIG
CCCCEEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCC
PELMEKLQKQAERFDTQIVYDTINAVDLQNKPFKLVGEVEQYTCDTLIIATGATAKYLGL
HHHHHHHHHHHHHHCCEEEEECCCEEECCCCCCCEEECHHHHCCCEEEEECCCCEEEECC
ESEEKFMGKGVSACATCDGFFYKNKDVAVVGGGNTAVEEALFLSNIAKSVTLIHRRDTLR
CCHHHHHCCCCCHHEECCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHEEEEHHHHHH
SEKILIDKLMEKAQHGNINIIWNTTLEEVLGDDMGVNALRIKNIKTNEESQIDVAGVFIA
HHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCCEEEEEECCCCCCCCEEEEEEEEE
IGHTPNTSIFAGQLEMENGYIKVKSGLAGDATQTNIKGVFAAGDVADHVYKQAVTSAGTG
ECCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHCCCC
CMAALDAEKYLDNLDQ
CEEECCHHHHHHHCCC
>Mature Secondary Structure 
ANHHKLIILGSGPAGYTAAIYAARANLKPVIITGMQPGGQLTTTTDVDNWPGEPDGIIG
CCCEEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCC
PELMEKLQKQAERFDTQIVYDTINAVDLQNKPFKLVGEVEQYTCDTLIIATGATAKYLGL
HHHHHHHHHHHHHHCCEEEEECCCEEECCCCCCCEEECHHHHCCCEEEEECCCCEEEECC
ESEEKFMGKGVSACATCDGFFYKNKDVAVVGGGNTAVEEALFLSNIAKSVTLIHRRDTLR
CCHHHHHCCCCCHHEECCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHEEEEHHHHHH
SEKILIDKLMEKAQHGNINIIWNTTLEEVLGDDMGVNALRIKNIKTNEESQIDVAGVFIA
HHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCCEEEEEECCCCCCCCEEEEEEEEE
IGHTPNTSIFAGQLEMENGYIKVKSGLAGDATQTNIKGVFAAGDVADHVYKQAVTSAGTG
ECCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHCCCC
CMAALDAEKYLDNLDQ
CEEECCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]