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The map label for this gene is lolC [H]

Identifier: 89255884

GI number: 89255884

Start: 450781

End: 452085

Strand: Direct

Name: lolC [H]

Synonym: FTL_0474

Alternate gene names: 89255884

Gene position: 450781-452085 (Clockwise)

Preceding gene: 89255883

Following gene: 89255885

Centisome position: 23.78

GC content: 34.71

Gene sequence:

>1305_bases
ATGTTATTCTATAGGGTAATTTTTATTGCAAGAAAAAATTTAATGTTTAAAAGCTTACCACTATTTATCGGATTAAGATA
TATCCGTGCTAAGAAGCGTAACCGGTTTATATCTATTATATCGGCAATATCATTTTTGGGTATTTCTCTAGGTGTGGCTG
TACTTATCACAGTGATGTCGGTGATGAATGGGTTTGATCAGCAGATCAAAAGCAAAATTCTAATGATGGTACCACCTTTA
AAAGTGTATCAATTAGGTGGGGAAGTTACTGATTGGCCAAACTTAGCCAAAGAAGTTGAGAAAAGTACTCCAAGTGTTAC
TGCAGTAGCTCCGATAGTAGAATCACAAGGTTTACTTAGTGCAAATAGTGGTAGTAGCACGACAGCATTTGTACAAATTC
AGGGTATAGAACCTAAGTATCAAACCAAAGTACTACCTATAGCTGAGCATATTGTCGATGGTAAGCTGTCATCGTTAGAT
GATAATCAAGGTTATAATATAGTTTTAGGTAGTGTCTTGGCTGATAATTTAGGTGTTAAAGTTGGTGATAAGGTGACTTT
AATCGTACCAAAGATTAGTCTAACGCCGGCTGGGATGATCCCAAGAATTAAGCAGTTTAGAGTGTCTGGAATATTCTCTG
TGAGCTATCAATATGATGCTTATTATGCGATGATTAATATTAAGGATGCACAAAAAGTTTTTGAGACGGGTAATTCAGTA
TCATCTCTTCAACTAAGTGTAAAAAATATCTATGATGCACCACTTGTTAAAGACAAACTCAATGATGGTGCCATTCCTCC
TTACTATTTCACTCGTGATTGGACGGATGAGAATAAATCTTTCTTTGACGCCTTAAAAATGGAAAAAACGATGATGTTTT
TTATCCTATTACTAATAATTACTGTCGCTGTATTTAATTTATTATCATCTTTAGTTATGGTTGTCACTGATAAGCGTAGT
GATATAGCTATTCTTAGAACTATGGGGATGTCATCGCGACAAATTATAACGGTATTTATATACCAAGGTTTTATTATTGG
TTTGATAGGTACAGTTATTGGTGTATTGCTTGGTATACTTCTTTCAACTTATGCCACAGAGATAGTTAATTTTATCCAGA
ATCTTACTGGTAAGCAATTTTTGAGCGCAAGTGTTTATCTTATAAATTATATCCCATCGGAGCTTATGTGGTCAGACGTT
ATAAAAGTTACTTTGGTTTCTATGTTTTTAAGTTTCTTAGCGACACTTTATCCTGCTTGGAGTGCTTCTAAGGTTCAGCC
AGTGGAGGCTTTAAGATATGAATGA

Upstream 100 bases:

>100_bases
TAATAGTTAATTAATTTATCTGCAATATAAAAATAGTTGTTATCACATCAGTTACGATGATTTAGTTAGATGTTTTTGAA
ATGTTTTTTCATAGCTTAAT

Downstream 100 bases:

>100_bases
TGTTGTTTTAAGTTGCAAAAATGTTTCAAAAAAATATACAGAATTTAAAACTGATATAGCTATCTTAAAAGATGTAAACC
TCGAGATTAAAAAAGGTGAA

Product: lipoprotein releasing system, subunit C,putative membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MLFYRVIFIARKNLMFKSLPLFIGLRYIRAKKRNRFISIISAISFLGISLGVAVLITVMSVMNGFDQQIKSKILMMVPPL
KVYQLGGEVTDWPNLAKEVEKSTPSVTAVAPIVESQGLLSANSGSSTTAFVQIQGIEPKYQTKVLPIAEHIVDGKLSSLD
DNQGYNIVLGSVLADNLGVKVGDKVTLIVPKISLTPAGMIPRIKQFRVSGIFSVSYQYDAYYAMINIKDAQKVFETGNSV
SSLQLSVKNIYDAPLVKDKLNDGAIPPYYFTRDWTDENKSFFDALKMEKTMMFFILLLIITVAVFNLLSSLVMVVTDKRS
DIAILRTMGMSSRQIITVFIYQGFIIGLIGTVIGVLLGILLSTYATEIVNFIQNLTGKQFLSASVYLINYIPSELMWSDV
IKVTLVSMFLSFLATLYPAWSASKVQPVEALRYE

Sequences:

>Translated_434_residues
MLFYRVIFIARKNLMFKSLPLFIGLRYIRAKKRNRFISIISAISFLGISLGVAVLITVMSVMNGFDQQIKSKILMMVPPL
KVYQLGGEVTDWPNLAKEVEKSTPSVTAVAPIVESQGLLSANSGSSTTAFVQIQGIEPKYQTKVLPIAEHIVDGKLSSLD
DNQGYNIVLGSVLADNLGVKVGDKVTLIVPKISLTPAGMIPRIKQFRVSGIFSVSYQYDAYYAMINIKDAQKVFETGNSV
SSLQLSVKNIYDAPLVKDKLNDGAIPPYYFTRDWTDENKSFFDALKMEKTMMFFILLLIITVAVFNLLSSLVMVVTDKRS
DIAILRTMGMSSRQIITVFIYQGFIIGLIGTVIGVLLGILLSTYATEIVNFIQNLTGKQFLSASVYLINYIPSELMWSDV
IKVTLVSMFLSFLATLYPAWSASKVQPVEALRYE
>Mature_434_residues
MLFYRVIFIARKNLMFKSLPLFIGLRYIRAKKRNRFISIISAISFLGISLGVAVLITVMSVMNGFDQQIKSKILMMVPPL
KVYQLGGEVTDWPNLAKEVEKSTPSVTAVAPIVESQGLLSANSGSSTTAFVQIQGIEPKYQTKVLPIAEHIVDGKLSSLD
DNQGYNIVLGSVLADNLGVKVGDKVTLIVPKISLTPAGMIPRIKQFRVSGIFSVSYQYDAYYAMINIKDAQKVFETGNSV
SSLQLSVKNIYDAPLVKDKLNDGAIPPYYFTRDWTDENKSFFDALKMEKTMMFFILLLIITVAVFNLLSSLVMVVTDKRS
DIAILRTMGMSSRQIITVFIYQGFIIGLIGTVIGVLLGILLSTYATEIVNFIQNLTGKQFLSASVYLINYIPSELMWSDV
IKVTLVSMFLSFLATLYPAWSASKVQPVEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=419, Percent_Identity=35.0835322195704, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1787360, Length=423, Percent_Identity=35.2245862884161, Blast_Score=226, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 48231; Mature: 48231

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFYRVIFIARKNLMFKSLPLFIGLRYIRAKKRNRFISIISAISFLGISLGVAVLITVMS
CHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMNGFDQQIKSKILMMVPPLKVYQLGGEVTDWPNLAKEVEKSTPSVTAVAPIVESQGLLS
HHHHHHHHHHHCEEHCCCCHHHEECCCCCCCCHHHHHHHHHCCCCEEEEHHHHHCCCCEE
ANSGSSTTAFVQIQGIEPKYQTKVLPIAEHIVDGKLSSLDDNQGYNIVLGSVLADNLGVK
CCCCCCEEEEEEEECCCCHHHCCHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHCCCCCE
VGDKVTLIVPKISLTPAGMIPRIKQFRVSGIFSVSYQYDAYYAMINIKDAQKVFETGNSV
ECCEEEEEEECEECCCCCCCHHHHHHHHHEEEEEEEEECEEEEEEEEHHHHHHHHCCCCH
SSLQLSVKNIYDAPLVKDKLNDGAIPPYYFTRDWTDENKSFFDALKMEKTMMFFILLLII
HHHEEEHHHHCCCCCHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TVAVFNLLSSLVMVVTDKRSDIAILRTMGMSSRQIITVFIYQGFIIGLIGTVIGVLLGIL
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHH
LSTYATEIVNFIQNLTGKQFLSASVYLINYIPSELMWSDVIKVTLVSMFLSFLATLYPAW
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SASKVQPVEALRYE
CCCCCCHHHHHCCC
>Mature Secondary Structure
MLFYRVIFIARKNLMFKSLPLFIGLRYIRAKKRNRFISIISAISFLGISLGVAVLITVMS
CHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMNGFDQQIKSKILMMVPPLKVYQLGGEVTDWPNLAKEVEKSTPSVTAVAPIVESQGLLS
HHHHHHHHHHHCEEHCCCCHHHEECCCCCCCCHHHHHHHHHCCCCEEEEHHHHHCCCCEE
ANSGSSTTAFVQIQGIEPKYQTKVLPIAEHIVDGKLSSLDDNQGYNIVLGSVLADNLGVK
CCCCCCEEEEEEEECCCCHHHCCHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHCCCCCE
VGDKVTLIVPKISLTPAGMIPRIKQFRVSGIFSVSYQYDAYYAMINIKDAQKVFETGNSV
ECCEEEEEEECEECCCCCCCHHHHHHHHHEEEEEEEEECEEEEEEEEHHHHHHHHCCCCH
SSLQLSVKNIYDAPLVKDKLNDGAIPPYYFTRDWTDENKSFFDALKMEKTMMFFILLLII
HHHEEEHHHHCCCCCHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TVAVFNLLSSLVMVVTDKRSDIAILRTMGMSSRQIITVFIYQGFIIGLIGTVIGVLLGIL
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHH
LSTYATEIVNFIQNLTGKQFLSASVYLINYIPSELMWSDVIKVTLVSMFLSFLATLYPAW
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SASKVQPVEALRYE
CCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]