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The map label for this gene is oxaA [H]

Identifier: 89255612

GI number: 89255612

Start: 178984

End: 180639

Strand: Direct

Name: oxaA [H]

Synonym: FTL_0178

Alternate gene names: 89255612

Gene position: 178984-180639 (Clockwise)

Preceding gene: 89255611

Following gene: 89255613

Centisome position: 9.44

GC content: 33.51

Gene sequence:

>1656_bases
ATGAAAGCTAATCATATAAGAATATTACTGTTAGTCACAATAGCAATAATGTTTATCTCGTTGATGGGAAAATGGGAGCA
AACATTCCCTGCTGACAATACTAAACAGCAAACATCAGCCACACAAAATAATAGTCACTACGACAATGCAGATTCAAGCA
CAAATACTGATGTAACTATAACTGATGCAAAAAGCTCTTTAGCTAAAGAGACTAATTTTTCTAAGTATGATAATGCTAAA
AGTATCACAATTAATACTGTAGTTTTTAAAGATGTAAAAGTTAGTCTACTAGATGGTGCAATTATATCAGCATCTTTAAA
AGATTACAGTATCAGTCTTGATGATAAGACTCCGATGAGTCTACTTACAGATAAATCAGGTTCTGAATATATTGCTAAGA
GCACGATAGTTGTAAATAAGCAACCTATTAGTGTTAATTTTGAAGACCAAGGCATCAAAATAGAGAATAGCAAACAAATC
CTAACGCTAACTGGTAGTGCTGATGGCTTGCAAATAACTAGAACATATACCTTTGATGATACTAAATACAATATATCAGT
GTCACAAAACATAAAAAATACAACATCTGCACCAGTTAATGTAATTGTTGATGATTCATTTGCTAGAGATTTTGATCCTG
CTGGTGATAGCTTTAGCTTATTAAATGCTCATAGCTATACTTTTACAGGTGTTGCATACTCTACAGCTAAAGATAGCTTT
AGAAAAGAATCCTTTAAAGATATCTCAAAAACTAATGGTCAGCCAACAGTAATAAATAGTGATGGTCAAGGTTGGGTTGC
ATTTTTACAACATTACTTTGTAAGTGCATGGATACCACAATCTACTAATGCAAAAATTTATTATAAAAACCTAAATGGTG
ATGTATTCGAAGCTGGAGCATTTACAGGTGCGACAATAGCACCAAACCAGTCAGAAAATATTTCTTCTATTTTATATACT
GGTCCAATAATAAAAGCCAATCTAGTAGACTTAGCACCAAATCTAGAAAAAACACTTGACTATGGAATGTTGTCTTTCTT
CTCAGAAATAATTTTCTGGGTTATGAATCACATACATTCGCTAGTTGGTAACTGGGGCTTAGCAATTATTTTAGTAACAT
GTTTGATTAAACTTATTTTCTACCCTCTTTCTGCGAAGAGCTATCGCTCTATGGCAAAAATGAGAATGCTACAGCCTAGA
ATTAAGCGTCTGCAAGAAACATACAAAGATGATCGTCAAGCTCTTGGTAAGAAGATGATGGAGTTGTACAAAGAAGAGAA
AGTAAACCCACTTAGTGGCTGTTTGCCTATGCTTATACAGATTCCAATTTTCATCTCATTATACTGGGTATTACTCGAAT
CCGTAGAGCTAAGACAAGCACCTTTTATATTCTGGATTCATGATTTATCGATGAAAGATCCATATTTTGTACTTCCAGTG
CTAATGGGATTATCAATGTTTTTACAACAAAAATTATCACCAGCTCCAGCTGATCCTATGCAGGCAAAAGTAATGATGTT
TTTACCAGTAATATTTACATTCCTGTTCGCATCGTTCCCATCTGGTCTAGTATTATATTGGCTGACGAATAACCTAATCA
GTATTTCACAACAGTGGATTATTACAAGACACTATCAAGCTACTCATAAAAAATAA

Upstream 100 bases:

>100_bases
TGTACTTAACTACACGTAGACTCTTGAGGTGTCATCCACTCTCAAAAAGAGATTACTACGACTTAGTTCCTTGTAAAAAT
AAAAAAGGTTAAAATAAACA

Downstream 100 bases:

>100_bases
ATATACATGGATAAATCTCTACTTAAACCAAAATATTGGGGTATATGGATTATAATTTGGATCGCCAAGTTTATAGTAAA
TATACTTCCATACAAAATGC

Product: inner-membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MKANHIRILLLVTIAIMFISLMGKWEQTFPADNTKQQTSATQNNSHYDNADSSTNTDVTITDAKSSLAKETNFSKYDNAK
SITINTVVFKDVKVSLLDGAIISASLKDYSISLDDKTPMSLLTDKSGSEYIAKSTIVVNKQPISVNFEDQGIKIENSKQI
LTLTGSADGLQITRTYTFDDTKYNISVSQNIKNTTSAPVNVIVDDSFARDFDPAGDSFSLLNAHSYTFTGVAYSTAKDSF
RKESFKDISKTNGQPTVINSDGQGWVAFLQHYFVSAWIPQSTNAKIYYKNLNGDVFEAGAFTGATIAPNQSENISSILYT
GPIIKANLVDLAPNLEKTLDYGMLSFFSEIIFWVMNHIHSLVGNWGLAIILVTCLIKLIFYPLSAKSYRSMAKMRMLQPR
IKRLQETYKDDRQALGKKMMELYKEEKVNPLSGCLPMLIQIPIFISLYWVLLESVELRQAPFIFWIHDLSMKDPYFVLPV
LMGLSMFLQQKLSPAPADPMQAKVMMFLPVIFTFLFASFPSGLVLYWLTNNLISISQQWIITRHYQATHKK

Sequences:

>Translated_551_residues
MKANHIRILLLVTIAIMFISLMGKWEQTFPADNTKQQTSATQNNSHYDNADSSTNTDVTITDAKSSLAKETNFSKYDNAK
SITINTVVFKDVKVSLLDGAIISASLKDYSISLDDKTPMSLLTDKSGSEYIAKSTIVVNKQPISVNFEDQGIKIENSKQI
LTLTGSADGLQITRTYTFDDTKYNISVSQNIKNTTSAPVNVIVDDSFARDFDPAGDSFSLLNAHSYTFTGVAYSTAKDSF
RKESFKDISKTNGQPTVINSDGQGWVAFLQHYFVSAWIPQSTNAKIYYKNLNGDVFEAGAFTGATIAPNQSENISSILYT
GPIIKANLVDLAPNLEKTLDYGMLSFFSEIIFWVMNHIHSLVGNWGLAIILVTCLIKLIFYPLSAKSYRSMAKMRMLQPR
IKRLQETYKDDRQALGKKMMELYKEEKVNPLSGCLPMLIQIPIFISLYWVLLESVELRQAPFIFWIHDLSMKDPYFVLPV
LMGLSMFLQQKLSPAPADPMQAKVMMFLPVIFTFLFASFPSGLVLYWLTNNLISISQQWIITRHYQATHKK
>Mature_551_residues
MKANHIRILLLVTIAIMFISLMGKWEQTFPADNTKQQTSATQNNSHYDNADSSTNTDVTITDAKSSLAKETNFSKYDNAK
SITINTVVFKDVKVSLLDGAIISASLKDYSISLDDKTPMSLLTDKSGSEYIAKSTIVVNKQPISVNFEDQGIKIENSKQI
LTLTGSADGLQITRTYTFDDTKYNISVSQNIKNTTSAPVNVIVDDSFARDFDPAGDSFSLLNAHSYTFTGVAYSTAKDSF
RKESFKDISKTNGQPTVINSDGQGWVAFLQHYFVSAWIPQSTNAKIYYKNLNGDVFEAGAFTGATIAPNQSENISSILYT
GPIIKANLVDLAPNLEKTLDYGMLSFFSEIIFWVMNHIHSLVGNWGLAIILVTCLIKLIFYPLSAKSYRSMAKMRMLQPR
IKRLQETYKDDRQALGKKMMELYKEEKVNPLSGCLPMLIQIPIFISLYWVLLESVELRQAPFIFWIHDLSMKDPYFVLPV
LMGLSMFLQQKLSPAPADPMQAKVMMFLPVIFTFLFASFPSGLVLYWLTNNLISISQQWIITRHYQATHKK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=558, Percent_Identity=36.5591397849462, Blast_Score=343, Evalue=2e-95,
Organism=Drosophila melanogaster, GI24662345, Length=192, Percent_Identity=29.6875, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356443, Length=192, Percent_Identity=29.6875, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 61953; Mature: 61953

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKANHIRILLLVTIAIMFISLMGKWEQTFPADNTKQQTSATQNNSHYDNADSSTNTDVTI
CCCCCEEHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEEE
TDAKSSLAKETNFSKYDNAKSITINTVVFKDVKVSLLDGAIISASLKDYSISLDDKTPMS
ECCHHHHHHHCCCCCCCCCCEEEEEEEEEECEEEEEECCEEEEEECCCEEEECCCCCCHH
LLTDKSGSEYIAKSTIVVNKQPISVNFEDQGIKIENSKQILTLTGSADGLQITRTYTFDD
HHCCCCCCCEEEEEEEEEECCCEEEEECCCCEEEECCCEEEEEECCCCCEEEEEEEEECC
TKYNISVSQNIKNTTSAPVNVIVDDSFARDFDPAGDSFSLLNAHSYTFTGVAYSTAKDSF
CEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCEEEEEEEEHHHHHHH
RKESFKDISKTNGQPTVINSDGQGWVAFLQHYFVSAWIPQSTNAKIYYKNLNGDVFEAGA
HHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECCC
FTGATIAPNQSENISSILYTGPIIKANLVDLAPNLEKTLDYGMLSFFSEIIFWVMNHIHS
CCCCEECCCCCCCCHHHEEECCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGNWGLAIILVTCLIKLIFYPLSAKSYRSMAKMRMLQPRIKRLQETYKDDRQALGKKMM
HHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELYKEEKVNPLSGCLPMLIQIPIFISLYWVLLESVELRQAPFIFWIHDLSMKDPYFVLPV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHH
LMGLSMFLQQKLSPAPADPMQAKVMMFLPVIFTFLFASFPSGLVLYWLTNNLISISQQWI
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHCHHHE
ITRHYQATHKK
EEEECHHCCCC
>Mature Secondary Structure
MKANHIRILLLVTIAIMFISLMGKWEQTFPADNTKQQTSATQNNSHYDNADSSTNTDVTI
CCCCCEEHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEEE
TDAKSSLAKETNFSKYDNAKSITINTVVFKDVKVSLLDGAIISASLKDYSISLDDKTPMS
ECCHHHHHHHCCCCCCCCCCEEEEEEEEEECEEEEEECCEEEEEECCCEEEECCCCCCHH
LLTDKSGSEYIAKSTIVVNKQPISVNFEDQGIKIENSKQILTLTGSADGLQITRTYTFDD
HHCCCCCCCEEEEEEEEEECCCEEEEECCCCEEEECCCEEEEEECCCCCEEEEEEEEECC
TKYNISVSQNIKNTTSAPVNVIVDDSFARDFDPAGDSFSLLNAHSYTFTGVAYSTAKDSF
CEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCEEEEEEEEHHHHHHH
RKESFKDISKTNGQPTVINSDGQGWVAFLQHYFVSAWIPQSTNAKIYYKNLNGDVFEAGA
HHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECCC
FTGATIAPNQSENISSILYTGPIIKANLVDLAPNLEKTLDYGMLSFFSEIIFWVMNHIHS
CCCCEECCCCCCCCHHHEEECCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGNWGLAIILVTCLIKLIFYPLSAKSYRSMAKMRMLQPRIKRLQETYKDDRQALGKKMM
HHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELYKEEKVNPLSGCLPMLIQIPIFISLYWVLLESVELRQAPFIFWIHDLSMKDPYFVLPV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHH
LMGLSMFLQQKLSPAPADPMQAKVMMFLPVIFTFLFASFPSGLVLYWLTNNLISISQQWI
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHCHHHE
ITRHYQATHKK
EEEECHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA