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The map label for this gene is proP [C]

Identifier: 89255596

GI number: 89255596

Start: 166392

End: 167090

Strand: Reverse

Name: proP [C]

Synonym: FTL_0162

Alternate gene names: 89255596

Gene position: 167090-166392 (Counterclockwise)

Preceding gene: 89255597

Following gene: 89255595

Centisome position: 8.81

GC content: 30.47

Gene sequence:

>699_bases
ATGGCAAATGGTGGTTGGCGGATACTTTTGGATATGGCAATTATACTAGTAGTGTTATCATTTTTTATTAAGCACAGCGG
TGAGCAAAAAAAATCACAAAAGTCTGATATTAGCTTAACAAAGATTATAATTAAAAATTATAAAAGTTTAGTTTATATGA
TTTTATTGTGTTTTCCTGGTGCTGTCGTTGCGTATTTTCAGATCATGATTTTGCCGAATATCATTAAACAAATTCTCAAG
CAAGTTGATGTTAATGTTGCAATACTTACAACGATTAGCATTATAATGTTTATCATTACATGTAATATTGCTGCGAGATT
GACAAAGTACTTCAAAATAAAAACTATTACAGCATTTGGTTTAGTTTTGATGATTGTATTATCGTTACCTATGTATGCTT
TGTATAAGGCAAATAATGACTTATTGATAGTCTTCTTTGTAGTTATGGGAGCAGTATTTGGTATATTCTATGGTAACATT
ATGGTGCTATTTACAGAGTGCTTGCCAAAAGAAATTCGTTATACAGGCTTTGCTTTAGCTTATAATATTGGTTTTGGCGT
ATTTGGCGGTTTGTTACCATTTTTATGCTTTTTCCTTGCAGAAACTGTATCTGACTATACAGCAATTGGGATTATATGTA
TAAGTGCAATTGTCGGTTTAATAACACTATATAAGCTGAAAACCTTAAGAATTCTATAA

Upstream 100 bases:

>100_bases
GGCTAAAGCTGGGGTAAATGTAATTACTAGTGCTTTTGGTGGGATTTTAATGGTAATCATAACCTTTTAGGTTACAAGGT
ATCTGATACCAGATGAAACT

Downstream 100 bases:

>100_bases
TAAATAGTAAATAACTTTAACTAATTCATTTTATGGGCACTATTTATGAATCATTACTTTTTAAATGAAAGTTGTTTTAT
CTATAATATTAGTGATAAAT

Product: hypothetical protein

Products: betaine [Cytoplasm]; Proton [Cytoplasm]; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MANGGWRILLDMAIILVVLSFFIKHSGEQKKSQKSDISLTKIIIKNYKSLVYMILLCFPGAVVAYFQIMILPNIIKQILK
QVDVNVAILTTISIIMFIITCNIAARLTKYFKIKTITAFGLVLMIVLSLPMYALYKANNDLLIVFFVVMGAVFGIFYGNI
MVLFTECLPKEIRYTGFALAYNIGFGVFGGLLPFLCFFLAETVSDYTAIGIICISAIVGLITLYKLKTLRIL

Sequences:

>Translated_232_residues
MANGGWRILLDMAIILVVLSFFIKHSGEQKKSQKSDISLTKIIIKNYKSLVYMILLCFPGAVVAYFQIMILPNIIKQILK
QVDVNVAILTTISIIMFIITCNIAARLTKYFKIKTITAFGLVLMIVLSLPMYALYKANNDLLIVFFVVMGAVFGIFYGNI
MVLFTECLPKEIRYTGFALAYNIGFGVFGGLLPFLCFFLAETVSDYTAIGIICISAIVGLITLYKLKTLRIL
>Mature_231_residues
ANGGWRILLDMAIILVVLSFFIKHSGEQKKSQKSDISLTKIIIKNYKSLVYMILLCFPGAVVAYFQIMILPNIIKQILKQ
VDVNVAILTTISIIMFIITCNIAARLTKYFKIKTITAFGLVLMIVLSLPMYALYKANNDLLIVFFVVMGAVFGIFYGNIM
VLFTECLPKEIRYTGFALAYNIGFGVFGGLLPFLCFFLAETVSDYTAIGIICISAIVGLITLYKLKTLRIL

Specific function: Stretch-Inactivated Proline/Betaine Transporter. Prop Is Both An Osmosensor And An Osmoregulator Which Is Available To Participate Early In The Bacterial Osmoregulatory Response. Mediates The Active Accumulation Of Solutes Such As Proline, Glycine Betaine

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25947; Mature: 25816

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANGGWRILLDMAIILVVLSFFIKHSGEQKKSQKSDISLTKIIIKNYKSLVYMILLCFPG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AVVAYFQIMILPNIIKQILKQVDVNVAILTTISIIMFIITCNIAARLTKYFKIKTITAFG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVLMIVLSLPMYALYKANNDLLIVFFVVMGAVFGIFYGNIMVLFTECLPKEIRYTGFALA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YNIGFGVFGGLLPFLCFFLAETVSDYTAIGIICISAIVGLITLYKLKTLRIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANGGWRILLDMAIILVVLSFFIKHSGEQKKSQKSDISLTKIIIKNYKSLVYMILLCFPG
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AVVAYFQIMILPNIIKQILKQVDVNVAILTTISIIMFIITCNIAARLTKYFKIKTITAFG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVLMIVLSLPMYALYKANNDLLIVFFVVMGAVFGIFYGNIMVLFTECLPKEIRYTGFALA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YNIGFGVFGGLLPFLCFFLAETVSDYTAIGIICISAIVGLITLYKLKTLRIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: betaine [Periplasm]; Proton [Periplasm]; L-proline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + betaine [Periplasm] = Proton [Cytoplasm] + betaine [Cytoplasm] Proton [Periplasm] + L-proline [Periplasm] = Proton [Cytoplasm] + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA