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The map label for this gene is 89255474

Identifier: 89255474

GI number: 89255474

Start: 25840

End: 26358

Strand: Direct

Name: 89255474

Synonym: FTL_0027

Alternate gene names: NA

Gene position: 25840-26358 (Clockwise)

Preceding gene: 89255473

Following gene: 89255478

Centisome position: 1.36

GC content: 26.4

Gene sequence:

>519_bases
ATGCCAATATCTGGAAATCCTGCTGCATTACAGGAAAAAAGAGCTTTAATTATGCTTGGTGCAACAGAAGAAGAATGTAA
GAGCTTTGTACATTTCTTAGAAGCGCTTAGTAATAAAATATTATATTTAGATATTGCTGGGTCTGCACTTAAAGAAAAAC
TTTGTATTAATGAAATGCTTTTTACTCAGTGGTTTAGTTATTGTGAGGCAATGCTATTAGCAGAAAATAATGGTATTAAA
ACAGAAGATTTTTTTAAAGCAATGTCACAAAGTGTTATATCATCACCTCTTTTGGTACAAAGAAGTCAATATTTCTTTGG
ATATAATGTAAATCCTTCAGATTTAAATATGATTTTGAAAGATATAGGTATAATCGAAGATTTTGTAAATAAATCAAAAA
CAAAAGTTACTTTATTACAAAAATTTAGAGAAGTAGTTGAATATGCTATTAAACATGATTTTACAAATCAAGATTTTTAT
GGGTTATATAGAGCTTATAAAGAAATTTATAAAAAATAA

Upstream 100 bases:

>100_bases
TTTAGTAAATCATACAATATTAGATGCGAGCACTCTTTCTGTAAGCTGATTTGAGCAACTTAATAAAGTCGTTACCCAAA
ATAATGGTAAATTAATAGAT

Downstream 100 bases:

>100_bases
CAAATTTTATTTTTTAGGATATTACTAATAAAGCCAATAGCGCCATCCTAATCGGAATACTATATTTGATTTGCTCAAAA
TATTTCGCACACTCAAGCTC

Product: 3-hydroxyisobutyrate dehydrogenase

Products: 2-methyl-3-oxopropanoate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MPISGNPAALQEKRALIMLGATEEECKSFVHFLEALSNKILYLDIAGSALKEKLCINEMLFTQWFSYCEAMLLAENNGIK
TEDFFKAMSQSVISSPLLVQRSQYFFGYNVNPSDLNMILKDIGIIEDFVNKSKTKVTLLQKFREVVEYAIKHDFTNQDFY
GLYRAYKEIYKK

Sequences:

>Translated_172_residues
MPISGNPAALQEKRALIMLGATEEECKSFVHFLEALSNKILYLDIAGSALKEKLCINEMLFTQWFSYCEAMLLAENNGIK
TEDFFKAMSQSVISSPLLVQRSQYFFGYNVNPSDLNMILKDIGIIEDFVNKSKTKVTLLQKFREVVEYAIKHDFTNQDFY
GLYRAYKEIYKK
>Mature_171_residues
PISGNPAALQEKRALIMLGATEEECKSFVHFLEALSNKILYLDIAGSALKEKLCINEMLFTQWFSYCEAMLLAENNGIKT
EDFFKAMSQSVISSPLLVQRSQYFFGYNVNPSDLNMILKDIGIIEDFVNKSKTKVTLLQKFREVVEYAIKHDFTNQDFYG
LYRAYKEIYKK

Specific function: Unknown

COG id: COG2084

COG function: function code I; 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.1.31

Molecular weight: Translated: 19843; Mature: 19712

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPISGNPAALQEKRALIMLGATEEECKSFVHFLEALSNKILYLDIAGSALKEKLCINEML
CCCCCCCHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHH
FTQWFSYCEAMLLAENNGIKTEDFFKAMSQSVISSPLLVQRSQYFFGYNVNPSDLNMILK
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHCCEEEECCCCHHHHHHHHH
DIGIIEDFVNKSKTKVTLLQKFREVVEYAIKHDFTNQDFYGLYRAYKEIYKK
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PISGNPAALQEKRALIMLGATEEECKSFVHFLEALSNKILYLDIAGSALKEKLCINEML
CCCCCCHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHH
FTQWFSYCEAMLLAENNGIKTEDFFKAMSQSVISSPLLVQRSQYFFGYNVNPSDLNMILK
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHCCEEEECCCCHHHHHHHHH
DIGIIEDFVNKSKTKVTLLQKFREVVEYAIKHDFTNQDFYGLYRAYKEIYKK
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-hydroxy-2-methylpropanoate; NAD+

Specific reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA