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The map label for this gene is garR [C]

Identifier: 89255473

GI number: 89255473

Start: 25480

End: 25788

Strand: Direct

Name: garR [C]

Synonym: FTL_0026

Alternate gene names: 89255473

Gene position: 25480-25788 (Clockwise)

Preceding gene: 89255470

Following gene: 89255474

Centisome position: 1.34

GC content: 30.42

Gene sequence:

>309_bases
ATGAGTAAACAAGTTGGTATTATTGGTTTAGGAAATATGGGATCTGTTGTTATAGATCACCTGCTAACATCAGGATATGA
GATTTTTATTCATAATAGAACCAAAGCAAAGGCTGAAAAATGGTTAAGAAATACACAAGTAGTTTGGTGTGATTCTCCAA
AAGAGTTAGCTGAAAATTGCGAAATAATAATTTGTTGTCTATATAATGATATTGCTGCAAAGAATGTTTATCTCAGTAAA
AATGGCTTAACTTCTATAAATTTAGTAAATCATACAATATTAGATGCGAGCACTCTTTCTGTAAGCTGA

Upstream 100 bases:

>100_bases
AAAAAGTGTTAATCAGTTTTGTGAGGTACTAAAATTAAATATAAAGGCAAGAGAGAATGATCTGGTAGGGTTTTTCTCTG
TACCAAAATAGGTGGCTAAA

Downstream 100 bases:

>100_bases
TTTGAGCAACTTAATAAAGTCGTTACCCAAAATAATGGTAAATTAATAGATATGCCAATATCTGGAAATCCTGCTGCATT
ACAGGAAAAAAGAGCTTTAA

Product: 3-hydroxyisobutyrate dehydrogenase

Products: 2-methyl-3-oxopropanoate; NADH; H+

Alternate protein names: Beta-Hydroxyacid Dehydrogenase; 2-Hydroxy-3-Oxopropionate Reductase

Number of amino acids: Translated: 102; Mature: 101

Protein sequence:

>102_residues
MSKQVGIIGLGNMGSVVIDHLLTSGYEIFIHNRTKAKAEKWLRNTQVVWCDSPKELAENCEIIICCLYNDIAAKNVYLSK
NGLTSINLVNHTILDASTLSVS

Sequences:

>Translated_102_residues
MSKQVGIIGLGNMGSVVIDHLLTSGYEIFIHNRTKAKAEKWLRNTQVVWCDSPKELAENCEIIICCLYNDIAAKNVYLSK
NGLTSINLVNHTILDASTLSVS
>Mature_101_residues
SKQVGIIGLGNMGSVVIDHLLTSGYEIFIHNRTKAKAEKWLRNTQVVWCDSPKELAENCEIIICCLYNDIAAKNVYLSKN
GLTSINLVNHTILDASTLSVS

Specific function: D-galactarate metabolism; third step. [C]

COG id: COG2084

COG function: function code I; 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.1.31

Molecular weight: Translated: 11251; Mature: 11120

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS00109 PROTEIN_KINASE_TYR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQVGIIGLGNMGSVVIDHLLTSGYEIFIHNRTKAKAEKWLRNTQVVWCDSPKELAENC
CCCCEEEEEECCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHCCEEEEECCHHHHHCCC
EIIICCLYNDIAAKNVYLSKNGLTSINLVNHTILDASTLSVS
CEEEEEECCCCCCCEEEEECCCCCEEEEEEEEEECCEEEECC
>Mature Secondary Structure 
SKQVGIIGLGNMGSVVIDHLLTSGYEIFIHNRTKAKAEKWLRNTQVVWCDSPKELAENC
CCCEEEEEECCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHCCEEEEECCHHHHHCCC
EIIICCLYNDIAAKNVYLSKNGLTSINLVNHTILDASTLSVS
CEEEEEECCCCCCCEEEEECCCCCEEEEEEEEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-hydroxy-2-methylpropanoate; NAD+

Specific reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA