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The map label for this gene is proP [C]

Identifier: 89255452

GI number: 89255452

Start: 2887

End: 3324

Strand: Reverse

Name: proP [C]

Synonym: FTL_0003

Alternate gene names: 89255452

Gene position: 3324-2887 (Counterclockwise)

Preceding gene: 89255455

Following gene: NA

Centisome position: 0.18

GC content: 26.48

Gene sequence:

>438_bases
ATGCTTTCTTCAATTATATTTGGATATATTGCTGATAGAATTGGTGGTAAAAAAGTTCTGATGTATTCTTGTATAGTCTT
ATTTATAGCTGTTTTACCAATATACCAAATTATTATAAAAAATCATCAATTAGTATCTATAGCTATTTTTTCTCTTGCTA
TTATAAGTGGTGCTGTAATAGGACCTATATTTGCAAATACGGCAGGGCTATTTCCTGTTAGAAATAGAAATACTGGTTTT
GGAATAAGTTTTAATATAAGCGTTTCTTTATTTGGAGGTACTGTTGCCTTTCTTATGACTTTATTAATTACTACTACTGG
AAATTATCTAATCCCAGCTTTCTATATAATGTTTTTATGCATACTTTTTTTATTGCTTTATTATTCATTCCAAAAGGCTT
ATAAAAATAGTTATTTCCTAAAACTACTTATTACTTAA

Upstream 100 bases:

>100_bases
TTAAAAAAATATTTAGAAAAGTGAATAATAGTTTTGAAAAATTTTGTGATGCTATCTCTTATGTGTTTAACAAAATACTC
TCGGATTAACTATAGTATTA

Downstream 100 bases:

>100_bases
ATTTTCATTGGCATAATAATAAACAAACTATTATCTTTCTCATCTTTGACTAAAGCACTCATATTTGGATTATCAAGGTA
GATAGACATAGTTTCTTCAC

Product: membrane protein, fragment

Products: betaine [Cytoplasm]; Proton [Cytoplasm]; L-proline [Cytoplasm] [C]

Alternate protein names: Facilitator Transporter; Proline/Betaine Transporter; Facilitator Family Transporter; Facilitator Superfamily Protein; Facilitator Superfamily Metabolite/H(+) Symporter; General Substrate Transporter Facilitator Superfamily; MetaboliteH+ Symporter Family Protein; MFS Transporter; Facilitator Superfamily Transporter Protein; MFS Superfamily Proline/ Betaine Transporter; MHS Family Metabolite MFS Transporter; Proline/Betaine Transporter Protein; Facilitator Superfamily Transporter; Facilitator Superfamilymetabolite/H Symporter; Citrate-Proton Symporter MFS General Substrate Transporter

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MLSSIIFGYIADRIGGKKVLMYSCIVLFIAVLPIYQIIIKNHQLVSIAIFSLAIISGAVIGPIFANTAGLFPVRNRNTGF
GISFNISVSLFGGTVAFLMTLLITTTGNYLIPAFYIMFLCILFLLLYYSFQKAYKNSYFLKLLIT

Sequences:

>Translated_145_residues
MLSSIIFGYIADRIGGKKVLMYSCIVLFIAVLPIYQIIIKNHQLVSIAIFSLAIISGAVIGPIFANTAGLFPVRNRNTGF
GISFNISVSLFGGTVAFLMTLLITTTGNYLIPAFYIMFLCILFLLLYYSFQKAYKNSYFLKLLIT
>Mature_145_residues
MLSSIIFGYIADRIGGKKVLMYSCIVLFIAVLPIYQIIIKNHQLVSIAIFSLAIISGAVIGPIFANTAGLFPVRNRNTGF
GISFNISVSLFGGTVAFLMTLLITTTGNYLIPAFYIMFLCILFLLLYYSFQKAYKNSYFLKLLIT

Specific function: Stretch-Inactivated Proline/Betaine Transporter. Prop Is Both An Osmosensor And An Osmoregulator Which Is Available To Participate Early In The Bacterial Osmoregulatory Response. Mediates The Active Accumulation Of Solutes Such As Proline, Glycine Betaine

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 16104; Mature: 16104

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSSIIFGYIADRIGGKKVLMYSCIVLFIAVLPIYQIIIKNHQLVSIAIFSLAIISGAVI
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GPIFANTAGLFPVRNRNTGFGISFNISVSLFGGTVAFLMTLLITTTGNYLIPAFYIMFLC
HHHHHCCCCCCEECCCCCCCCEEEEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ILFLLLYYSFQKAYKNSYFLKLLIT
HHHHHHHHHHHHHHCCCEEEEEEEC
>Mature Secondary Structure
MLSSIIFGYIADRIGGKKVLMYSCIVLFIAVLPIYQIIIKNHQLVSIAIFSLAIISGAVI
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GPIFANTAGLFPVRNRNTGFGISFNISVSLFGGTVAFLMTLLITTTGNYLIPAFYIMFLC
HHHHHCCCCCCEECCCCCCCCEEEEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ILFLLLYYSFQKAYKNSYFLKLLIT
HHHHHHHHHHHHHHCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: betaine [Periplasm]; Proton [Periplasm]; L-proline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + betaine [Periplasm] = Proton [Cytoplasm] + betaine [Cytoplasm] Proton [Periplasm] + L-proline [Periplasm] = Proton [Cytoplasm] + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA