BacMap

Definition	Jannaschia sp. CCS1 chromosome, complete genome.
Accession	NC_007802
Length	4,317,977

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The map label for this gene is fadB1 [H]

Identifier: 89056702

GI number: 89056702

Start: 4316262

End: 4317038

Strand: Direct

Name: fadB1 [H]

Synonym: Jann_4211

Alternate gene names: 89056702

Gene position: 4316262-4317038 (Clockwise)

Preceding gene: 89056701

Following gene: 89056703

Centisome position: 99.96

GC content: 60.49

Gene sequence:

>777_bases
ATGGCCTACGAGACCCTGATCGTCGACGTTGAAGATCATATCTGCCTCATTAAGCTGAACCGTCCCGACGCGCTGAATGC
GTTGAATGCGCAATTGCTGGAGGAGTTGGGCAAAGCGCTGAAAGCGGCAGAGGGCAACGACAAGGTGCGCTGCATCGTGT
TGACCGGCTCCGACAAGGCCTTTGCCGCCGGAGCCGACGTGACCGAGATGGCGGGCAAGAGTTTTGTCGATGTCGTGTTC
GAGGACATGTTCGCCAAGGACGACCGAGCCATCCGCGCCATTCGCAAGCCGATGATCGCCGCCGTGGCAGGCTATGCCTT
GGGCGGCGGGTGCGAGTTGGCCATGATCTGCGACTTCATCATCGCGGCCGAGAATGCGAAGTTTGGGCAGCCCGAGATCA
ATCTGGGCGTCATTGCGGGCATGGGCGGCACCCAGCGCCTGACCAAGCTGGTGGGCAAGTCCAAGGCGATGGACATGCAT
CTGACGGGGCGGTTCATGACAGCCGAAGAGGCTGAGCGCTCCGGGCTGGTATCGCGGGTCGTGCCAGTGAAGAAGCTGAT
GGAAGAGGCGATGGGCGCGGCGACGAAGATCTCCGAGAAATCCGCCATTGCAACCATGGCCGCGAAGGAGGCCGTGAACC
GCGCCGAGGAAACCCCGCTGAGCGAAGGTCTGCTTTTTGAGCGGCGTCTGTTCCATTCGTTGTTTGCCACCGAAGATCAA
TCCGAGGGTATGACCGCCTTTATCGAAAAGCGAGAGCCGCAGTTCCGGGACAAGTAG

Upstream 100 bases:

>100_bases
GCTCCAGTTTCTACTGTCCGGCCTGTCAGAGATAACTTGAACCCCGCGCCATCGGTGCTAACCCTCATGGCTCTGGTGCA
ACAGCGGATGAGCGCATTCC

Downstream 100 bases:

>100_bases
TTTCGGGACAATTGGGCTTCCCTTTTGGATGCACATTCCCTAAATGACGCCGTAGACATGCGTGTGAGGCCCGCTTTGGC
CAGATTCGCCCGGTAGTGAA

Product: short chain enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MAYETLIVDVEDHICLIKLNRPDALNALNAQLLEELGKALKAAEGNDKVRCIVLTGSDKAFAAGADVTEMAGKSFVDVVF
EDMFAKDDRAIRAIRKPMIAAVAGYALGGGCELAMICDFIIAAENAKFGQPEINLGVIAGMGGTQRLTKLVGKSKAMDMH
LTGRFMTAEEAERSGLVSRVVPVKKLMEEAMGAATKISEKSAIATMAAKEAVNRAEETPLSEGLLFERRLFHSLFATEDQ
SEGMTAFIEKREPQFRDK

Sequences:

>Translated_258_residues
MAYETLIVDVEDHICLIKLNRPDALNALNAQLLEELGKALKAAEGNDKVRCIVLTGSDKAFAAGADVTEMAGKSFVDVVF
EDMFAKDDRAIRAIRKPMIAAVAGYALGGGCELAMICDFIIAAENAKFGQPEINLGVIAGMGGTQRLTKLVGKSKAMDMH
LTGRFMTAEEAERSGLVSRVVPVKKLMEEAMGAATKISEKSAIATMAAKEAVNRAEETPLSEGLLFERRLFHSLFATEDQ
SEGMTAFIEKREPQFRDK
>Mature_257_residues
AYETLIVDVEDHICLIKLNRPDALNALNAQLLEELGKALKAAEGNDKVRCIVLTGSDKAFAAGADVTEMAGKSFVDVVFE
DMFAKDDRAIRAIRKPMIAAVAGYALGGGCELAMICDFIIAAENAKFGQPEINLGVIAGMGGTQRLTKLVGKSKAMDMHL
TGRFMTAEEAERSGLVSRVVPVKKLMEEAMGAATKISEKSAIATMAAKEAVNRAEETPLSEGLLFERRLFHSLFATEDQS
EGMTAFIEKREPQFRDK

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=247, Percent_Identity=54.251012145749, Blast_Score=257, Evalue=8e-69,
Organism=Homo sapiens, GI70995211, Length=266, Percent_Identity=30.8270676691729, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI20127408, Length=202, Percent_Identity=34.1584158415842, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI4502327, Length=252, Percent_Identity=35.3174603174603, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI68989263, Length=234, Percent_Identity=30.7692307692308, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI31542718, Length=248, Percent_Identity=31.0483870967742, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI260274832, Length=259, Percent_Identity=27.027027027027, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI45643119, Length=259, Percent_Identity=27.027027027027, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI260275230, Length=259, Percent_Identity=27.027027027027, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI37594471, Length=220, Percent_Identity=28.1818181818182, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI37594469, Length=199, Percent_Identity=30.6532663316583, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI150378541, Length=253, Percent_Identity=28.8537549407115, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI4757968, Length=268, Percent_Identity=25, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI49355787, Length=268, Percent_Identity=25, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI25453481, Length=267, Percent_Identity=24.7191011235955, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI51538573, Length=267, Percent_Identity=24.7191011235955, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI4757966, Length=203, Percent_Identity=28.0788177339901, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI51538581, Length=203, Percent_Identity=28.0788177339901, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI221136756, Length=200, Percent_Identity=29, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI221136753, Length=200, Percent_Identity=29, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI221307494, Length=200, Percent_Identity=29, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI213417737, Length=235, Percent_Identity=27.2340425531915, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI157694516, Length=235, Percent_Identity=27.2340425531915, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI62530384, Length=191, Percent_Identity=28.7958115183246, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI261878539, Length=138, Percent_Identity=34.7826086956522, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI116235487, Length=194, Percent_Identity=26.8041237113402, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI157694520, Length=214, Percent_Identity=28.0373831775701, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787659, Length=253, Percent_Identity=46.6403162055336, Blast_Score=224, Evalue=3e-60,
Organism=Escherichia coli, GI221142681, Length=260, Percent_Identity=36.1538461538462, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788597, Length=255, Percent_Identity=34.5098039215686, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI87082183, Length=260, Percent_Identity=31.9230769230769, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1787660, Length=260, Percent_Identity=32.6923076923077, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790281, Length=200, Percent_Identity=32, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1788682, Length=223, Percent_Identity=33.6322869955157, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17554946, Length=251, Percent_Identity=52.5896414342629, Blast_Score=261, Evalue=4e-70,
Organism=Caenorhabditis elegans, GI25145438, Length=244, Percent_Identity=50, Blast_Score=237, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI17536985, Length=264, Percent_Identity=30.3030303030303, Blast_Score=121, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17540714, Length=228, Percent_Identity=31.5789473684211, Blast_Score=113, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17534483, Length=264, Percent_Identity=29.1666666666667, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17560910, Length=241, Percent_Identity=31.1203319502075, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17558304, Length=220, Percent_Identity=30, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17540306, Length=233, Percent_Identity=32.1888412017167, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25144276, Length=219, Percent_Identity=31.5068493150685, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17508953, Length=219, Percent_Identity=31.5068493150685, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17508951, Length=219, Percent_Identity=31.5068493150685, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25144160, Length=209, Percent_Identity=30.622009569378, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI25144157, Length=209, Percent_Identity=30.622009569378, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17549921, Length=265, Percent_Identity=26.0377358490566, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17535521, Length=189, Percent_Identity=27.5132275132275, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=194, Percent_Identity=31.4432989690722, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI20129971, Length=246, Percent_Identity=54.0650406504065, Blast_Score=258, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24653477, Length=246, Percent_Identity=54.0650406504065, Blast_Score=258, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24653139, Length=252, Percent_Identity=33.7301587301587, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI19922422, Length=245, Percent_Identity=28.9795918367347, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24650670, Length=212, Percent_Identity=32.0754716981132, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21357171, Length=255, Percent_Identity=28.2352941176471, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI19920382, Length=223, Percent_Identity=33.6322869955157, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI19921000, Length=229, Percent_Identity=32.7510917030568, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24583077, Length=229, Percent_Identity=32.7510917030568, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24583079, Length=229, Percent_Identity=32.7510917030568, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24654903, Length=213, Percent_Identity=24.8826291079812, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI28571729, Length=175, Percent_Identity=30.2857142857143, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28571730, Length=175, Percent_Identity=30.2857142857143, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583165, Length=175, Percent_Identity=31.4285714285714, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19921018, Length=189, Percent_Identity=30.6878306878307, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27936; Mature: 27805

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYETLIVDVEDHICLIKLNRPDALNALNAQLLEELGKALKAAEGNDKVRCIVLTGSDKA
CCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
FAAGADVTEMAGKSFVDVVFEDMFAKDDRAIRAIRKPMIAAVAGYALGGGCELAMICDFI
EECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IAAENAKFGQPEINLGVIAGMGGTQRLTKLVGKSKAMDMHLTGRFMTAEEAERSGLVSRV
HHCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCEEEEECCCEECHHHHHHHHHHHHH
VPVKKLMEEAMGAATKISEKSAIATMAAKEAVNRAEETPLSEGLLFERRLFHSLFATEDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
SEGMTAFIEKREPQFRDK
CCCCEEEHCCCCCCCCCC
>Mature Secondary Structure 
AYETLIVDVEDHICLIKLNRPDALNALNAQLLEELGKALKAAEGNDKVRCIVLTGSDKA
CCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
FAAGADVTEMAGKSFVDVVFEDMFAKDDRAIRAIRKPMIAAVAGYALGGGCELAMICDFI
EECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IAAENAKFGQPEINLGVIAGMGGTQRLTKLVGKSKAMDMHLTGRFMTAEEAERSGLVSRV
HHCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCEEEEECCCEECHHHHHHHHHHHHH
VPVKKLMEEAMGAATKISEKSAIATMAAKEAVNRAEETPLSEGLLFERRLFHSLFATEDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
SEGMTAFIEKREPQFRDK
CCCCEEEHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]