Click here to switch to the map view.

The map label for this gene is allB [H]

Identifier: 89056619

GI number: 89056619

Start: 4236896

End: 4238284

Strand: Direct

Name: allB [H]

Synonym: Jann_4128

Alternate gene names: 89056619

Gene position: 4236896-4238284 (Clockwise)

Preceding gene: 89056618

Following gene: 89056622

Centisome position: 98.12

GC content: 63.07

Gene sequence:

>1389_bases
ATGAGCGCGTTGGATACGGTCATTGCCGGCGGCGACGTACTGTTGCCCGATGGGCTCACGCGGATTGATCTGGGCCTGAG
CGACGGCAAGGTTGCGGGGCTTTTCGCGCCCGGCACGGCGCCCAATGCTGCAGAGGTCATCAACGCCACGGGTCTGACAG
TTCTGCCCGGCATCGTAGACATCCACTTCCACGTCCGCGCGCCTGCCTACCCGGAACGCGGCACCGTGCTGTCCGAGACG
CGGGCGGCGGCGGCGGGTGGTGTCACCACGTTGTTTGAGATGCCGATCTCCAAACCCTGTTGCTCAACCCCCGAAGAACT
CGCCCACCGCCGCGATCATTTCGCAGAGACCGCGGTGATCGACTTTGCGCTCTACGCCGCGCCGGGGGATCTGACGGTAG
AGAGCCGGGACAAGATGATGGAACTGGGCTGCATCGCGTGGAAGATCTTCACCACGCCCGCACCAGACGGCCGCGCCGAC
GAATTCGAAGGGCTGGCTTTCCCGGATGAGGCGGACCAACTGCGTGCTTTGAGATTGCTGGCAACTACGGCGTTGCCGGT
CGTGGTCCATGCCGAAAGCGCACAACTTTTGGGATATTTCGAGGACGCCGCCAAAGCGCTGGACCCGGCGGATGCGGCCA
CACACAACGAATCTCGCCCTGCGATCTGCGAATCCGTCGCCGTGGCGAAACTTCTGACGATGAACATGGAGGCACAGGCC
AAGCTGCACATCGCCCATGTCACCAATGCGCAGACCGTCGATGTATTGCGCGCATTCTCGGGAACATCAGACTTCACCGC
CGAGACCTGCCCGCAATACCTTTTCACGACAGAGGCCGATGTTGCCAAGGCGGGCATCTATGCCAAGGTGAACCCGCCGA
TCCGCTTTCAATCGGATCAGGACGCACTTTGGCAAGCGATCGAGGACGGCGTGATCAACTACGTGACCACCGACCATGCG
CCGTTTGCCAAGGCAGAGAAACAGGCGTCCGAGGGTGATTTTCCAGGCGCTCCGCCCGGTGTGCCGGGGATCGAGTTCAT
TGTGCCCGCCATGCTGGACGCCGTGTCGCGGGGGCGGCTGAGTCTGAAACGCGCCCATGAGTTGATATGCTCCAACGGAG
CCAGGCGCTACGGCCTCTACCCGCACAAGGGCGCTCTACTGCCTGGAAGCTCTGCCGACGTGACGCTGGTGGATTTGAAG
GGTGAGACGACGTTTTCGCCCGAGACGATGCACACCCACGCCCGCGAGGTGGCCCATCTGTTCTATGGGCGCAGGCTCCG
CGGCAAGGTCACGCGCACCATCCGGGCTGGTCAGACGGTGTTTCACGATGGTGAGATCACCGGGTCCCGGGGCGCAGGCC
GCTACATCACACCCGGGTTCACGCCCTAG

Upstream 100 bases:

>100_bases
GTGCGGGCGGGCATGGGGTGGTCTTGTCGCCCAACTATGCCTCCATGCATCTGACCAATCTGGACGGCGTGGCCAAGGCC
CTGACGGAATTGGGGTTGAA

Downstream 100 bases:

>100_bases
CCATTTTCCTTCAAACGCGGATCGAGGAAATCCCGCAGCCAATCGCCGATGATATTGAAGGCCAACACGGTGAAAACGAT
GGCGAGGCCGGGAAACACTG

Product: dihydroorotase

Products: NA

Alternate protein names: Allantoin-utilizing enzyme [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSALDTVIAGGDVLLPDGLTRIDLGLSDGKVAGLFAPGTAPNAAEVINATGLTVLPGIVDIHFHVRAPAYPERGTVLSET
RAAAAGGVTTLFEMPISKPCCSTPEELAHRRDHFAETAVIDFALYAAPGDLTVESRDKMMELGCIAWKIFTTPAPDGRAD
EFEGLAFPDEADQLRALRLLATTALPVVVHAESAQLLGYFEDAAKALDPADAATHNESRPAICESVAVAKLLTMNMEAQA
KLHIAHVTNAQTVDVLRAFSGTSDFTAETCPQYLFTTEADVAKAGIYAKVNPPIRFQSDQDALWQAIEDGVINYVTTDHA
PFAKAEKQASEGDFPGAPPGVPGIEFIVPAMLDAVSRGRLSLKRAHELICSNGARRYGLYPHKGALLPGSSADVTLVDLK
GETTFSPETMHTHAREVAHLFYGRRLRGKVTRTIRAGQTVFHDGEITGSRGAGRYITPGFTP

Sequences:

>Translated_462_residues
MSALDTVIAGGDVLLPDGLTRIDLGLSDGKVAGLFAPGTAPNAAEVINATGLTVLPGIVDIHFHVRAPAYPERGTVLSET
RAAAAGGVTTLFEMPISKPCCSTPEELAHRRDHFAETAVIDFALYAAPGDLTVESRDKMMELGCIAWKIFTTPAPDGRAD
EFEGLAFPDEADQLRALRLLATTALPVVVHAESAQLLGYFEDAAKALDPADAATHNESRPAICESVAVAKLLTMNMEAQA
KLHIAHVTNAQTVDVLRAFSGTSDFTAETCPQYLFTTEADVAKAGIYAKVNPPIRFQSDQDALWQAIEDGVINYVTTDHA
PFAKAEKQASEGDFPGAPPGVPGIEFIVPAMLDAVSRGRLSLKRAHELICSNGARRYGLYPHKGALLPGSSADVTLVDLK
GETTFSPETMHTHAREVAHLFYGRRLRGKVTRTIRAGQTVFHDGEITGSRGAGRYITPGFTP
>Mature_461_residues
SALDTVIAGGDVLLPDGLTRIDLGLSDGKVAGLFAPGTAPNAAEVINATGLTVLPGIVDIHFHVRAPAYPERGTVLSETR
AAAAGGVTTLFEMPISKPCCSTPEELAHRRDHFAETAVIDFALYAAPGDLTVESRDKMMELGCIAWKIFTTPAPDGRADE
FEGLAFPDEADQLRALRLLATTALPVVVHAESAQLLGYFEDAAKALDPADAATHNESRPAICESVAVAKLLTMNMEAQAK
LHIAHVTNAQTVDVLRAFSGTSDFTAETCPQYLFTTEADVAKAGIYAKVNPPIRFQSDQDALWQAIEDGVINYVTTDHAP
FAKAEKQASEGDFPGAPPGVPGIEFIVPAMLDAVSRGRLSLKRAHELICSNGARRYGLYPHKGALLPGSSADVTLVDLKG
ETTFSPETMHTHAREVAHLFYGRRLRGKVTRTIRAGQTVFHDGEITGSRGAGRYITPGFTP

Specific function: Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring [H]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Allantoinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=443, Percent_Identity=26.1851015801354, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI4503375, Length=470, Percent_Identity=24.6808510638298, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI19923821, Length=471, Percent_Identity=24.6284501061571, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI4503051, Length=468, Percent_Identity=23.7179487179487, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4503379, Length=467, Percent_Identity=22.6980728051392, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI62422571, Length=468, Percent_Identity=23.7179487179487, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI4503377, Length=466, Percent_Identity=23.6051502145923, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI190194363, Length=465, Percent_Identity=22.3655913978495, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI87082175, Length=466, Percent_Identity=31.7596566523605, Blast_Score=197, Evalue=8e-52,
Organism=Escherichia coli, GI1786722, Length=444, Percent_Identity=27.4774774774775, Blast_Score=172, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI193204318, Length=421, Percent_Identity=28.978622327791, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17539558, Length=472, Percent_Identity=26.0593220338983, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71989490, Length=472, Percent_Identity=24.1525423728814, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322218, Length=403, Percent_Identity=26.5508684863524, Blast_Score=119, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24642586, Length=410, Percent_Identity=27.5609756097561, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI17137462, Length=460, Percent_Identity=24.5652173913043, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI221377917, Length=472, Percent_Identity=24.364406779661, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI18859883, Length=415, Percent_Identity=26.0240963855422, Blast_Score=92, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017593
- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.5 [H]

Molecular weight: Translated: 49267; Mature: 49136

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALDTVIAGGDVLLPDGLTRIDLGLSDGKVAGLFAPGTAPNAAEVINATGLTVLPGIVD
CCCHHHECCCCCEECCCCCEEEEECCCCCCEEEEECCCCCCCHHHHHCCCCCEEECCEEE
IHFHVRAPAYPERGTVLSETRAAAAGGVTTLFEMPISKPCCSTPEELAHRRDHFAETAVI
EEEEEECCCCCCCCCCHHHHHHHHCCCHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
DFALYAAPGDLTVESRDKMMELGCIAWKIFTTPAPDGRADEFEGLAFPDEADQLRALRLL
EEEEEECCCCCEECCHHHHHHHHEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ATTALPVVVHAESAQLLGYFEDAAKALDPADAATHNESRPAICESVAVAKLLTMNMEAQA
HHHHCEEEEEECCHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCE
KLHIAHVTNAQTVDVLRAFSGTSDFTAETCPQYLFTTEADVAKAGIYAKVNPPIRFQSDQ
EEEEEEECCCHHHHHHHHHCCCCCCCHHHCCHHEEECCCHHHHCCEEEECCCCEEECCCH
DALWQAIEDGVINYVTTDHAPFAKAEKQASEGDFPGAPPGVPGIEFIVPAMLDAVSRGRL
HHHHHHHHCCCEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHH
SLKRAHELICSNGARRYGLYPHKGALLPGSSADVTLVDLKGETTFSPETMHTHAREVAHL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
FYGRRLRGKVTRTIRAGQTVFHDGEITGSRGAGRYITPGFTP
HHCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SALDTVIAGGDVLLPDGLTRIDLGLSDGKVAGLFAPGTAPNAAEVINATGLTVLPGIVD
CCHHHECCCCCEECCCCCEEEEECCCCCCEEEEECCCCCCCHHHHHCCCCCEEECCEEE
IHFHVRAPAYPERGTVLSETRAAAAGGVTTLFEMPISKPCCSTPEELAHRRDHFAETAVI
EEEEEECCCCCCCCCCHHHHHHHHCCCHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
DFALYAAPGDLTVESRDKMMELGCIAWKIFTTPAPDGRADEFEGLAFPDEADQLRALRLL
EEEEEECCCCCEECCHHHHHHHHEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ATTALPVVVHAESAQLLGYFEDAAKALDPADAATHNESRPAICESVAVAKLLTMNMEAQA
HHHHCEEEEEECCHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCE
KLHIAHVTNAQTVDVLRAFSGTSDFTAETCPQYLFTTEADVAKAGIYAKVNPPIRFQSDQ
EEEEEEECCCHHHHHHHHHCCCCCCCHHHCCHHEEECCCHHHHCCEEEECCCCEEECCCH
DALWQAIEDGVINYVTTDHAPFAKAEKQASEGDFPGAPPGVPGIEFIVPAMLDAVSRGRL
HHHHHHHHCCCEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHH
SLKRAHELICSNGARRYGLYPHKGALLPGSSADVTLVDLKGETTFSPETMHTHAREVAHL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
FYGRRLRGKVTRTIRAGQTVFHDGEITGSRGAGRYITPGFTP
HHCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA