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The map label for this gene is frdB [H]

Identifier: 89056457

GI number: 89056457

Start: 4064218

End: 4064931

Strand: Direct

Name: frdB [H]

Synonym: Jann_3966

Alternate gene names: 89056457

Gene position: 4064218-4064931 (Clockwise)

Preceding gene: 89056455

Following gene: 89056458

Centisome position: 94.12

GC content: 63.03

Gene sequence:

>714_bases
ATGACGTCAGACGTCCTTAAAGTCACAATCGAGCGGGGGCAGGACGGCATGGACGTGTTCGAGGTGCCCGCCTATGACAG
CCAGACCGTCCTCGATGTCGTGTCCTGGGTGCAGCAGAACGCTGATCCGACGCTGAGCTACAGGTTCGCCTGCCGCGTGG
GGATGTGCGGATCCTGCGCGATGATGGTCAACGGCGTGCCGCGCTGGACCTGCCGGACCCATATCAACAAGGTTCTGGAC
GGAAACGCCGTCACCATAGGGCCGCTGCGCAACCTACCGGTGATCAAGGACCTCGCCGTCGATATGGACGCGTTCTTCGA
CAAATGGGTGGCGGCGGAAGGCGTCCATCACGGCTCCCTGACCCGCGACGATCCGATTGTGCCTGTCGATGAGGACAGCG
CGGGGCGGGTGGAGGCGAATGCCGGGATCGAGTGCATCAACTGCTCCGTCTGCTATGCGGCTTGTGACACGGTGGCGGGC
AATACCGATTACCTTGGACCAGCCGCCTTGCAGCGGGCCTGGACCTTGCTGAATGACGCGAAAGATGAGGGGAGGGTGGC
GATTTTGGATGCGGTGAGCGGGTCTGGCGGGTGCCACAACTGCCACTCTATGGGCTCCTGCACAGCGTATTGCCCCAACG
ATCTGGACCCGATGTCCGCCATTGCGGGCCTGAAGCGGGAGACCGCGAAAACCTGGTTCCGGAGGGGGCGCTGA

Upstream 100 bases:

>100_bases
GAAAACTTACAAAAAGATAAAGAATATATCGCATTCATAAAGAAATTCTGTCCGATATACTCTGCCACGAAGCCAGCCCC
AATGGAAAGCAAGCGCCCCC

Downstream 100 bases:

>100_bases
CATGCTGAGCCTACGCCTGTACATGCTGCAACGGATCACCGCGCTTTTGATGGCGCCGCTGGTGATCGGCCATCTCGCGG
TGATGATCTACGCGATCCAA

Product: succinate dehydrogenase subunit B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTSDVLKVTIERGQDGMDVFEVPAYDSQTVLDVVSWVQQNADPTLSYRFACRVGMCGSCAMMVNGVPRWTCRTHINKVLD
GNAVTIGPLRNLPVIKDLAVDMDAFFDKWVAAEGVHHGSLTRDDPIVPVDEDSAGRVEANAGIECINCSVCYAACDTVAG
NTDYLGPAALQRAWTLLNDAKDEGRVAILDAVSGSGGCHNCHSMGSCTAYCPNDLDPMSAIAGLKRETAKTWFRRGR

Sequences:

>Translated_237_residues
MTSDVLKVTIERGQDGMDVFEVPAYDSQTVLDVVSWVQQNADPTLSYRFACRVGMCGSCAMMVNGVPRWTCRTHINKVLD
GNAVTIGPLRNLPVIKDLAVDMDAFFDKWVAAEGVHHGSLTRDDPIVPVDEDSAGRVEANAGIECINCSVCYAACDTVAG
NTDYLGPAALQRAWTLLNDAKDEGRVAILDAVSGSGGCHNCHSMGSCTAYCPNDLDPMSAIAGLKRETAKTWFRRGR
>Mature_236_residues
TSDVLKVTIERGQDGMDVFEVPAYDSQTVLDVVSWVQQNADPTLSYRFACRVGMCGSCAMMVNGVPRWTCRTHINKVLDG
NAVTIGPLRNLPVIKDLAVDMDAFFDKWVAAEGVHHGSLTRDDPIVPVDEDSAGRVEANAGIECINCSVCYAACDTVAGN
TDYLGPAALQRAWTLLNDAKDEGRVAILDAVSGSGGCHNCHSMGSCTAYCPNDLDPMSAIAGLKRETAKTWFRRGR

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=201, Percent_Identity=31.8407960199005, Blast_Score=108, Evalue=5e-24,
Organism=Escherichia coli, GI1790596, Length=234, Percent_Identity=32.0512820512821, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI1786943, Length=200, Percent_Identity=32.5, Blast_Score=104, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17533915, Length=201, Percent_Identity=30.8457711442786, Blast_Score=107, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6322987, Length=202, Percent_Identity=30.6930693069307, Blast_Score=108, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24643156, Length=199, Percent_Identity=33.6683417085427, Blast_Score=120, Evalue=7e-28,
Organism=Drosophila melanogaster, GI17137106, Length=218, Percent_Identity=29.3577981651376, Blast_Score=111, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 25550; Mature: 25419

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDVLKVTIERGQDGMDVFEVPAYDSQTVLDVVSWVQQNADPTLSYRFACRVGMCGSCA
CCCCEEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHH
MMVNGVPRWTCRTHINKVLDGNAVTIGPLRNLPVIKDLAVDMDAFFDKWVAAEGVHHGSL
HHHCCCCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
TRDDPIVPVDEDSAGRVEANAGIECINCSVCYAACDTVAGNTDYLGPAALQRAWTLLNDA
CCCCCCEECCCCCCCEEECCCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
KDEGRVAILDAVSGSGGCHNCHSMGSCTAYCPNDLDPMSAIAGLKRETAKTWFRRGR
CCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSDVLKVTIERGQDGMDVFEVPAYDSQTVLDVVSWVQQNADPTLSYRFACRVGMCGSCA
CCCEEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHH
MMVNGVPRWTCRTHINKVLDGNAVTIGPLRNLPVIKDLAVDMDAFFDKWVAAEGVHHGSL
HHHCCCCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
TRDDPIVPVDEDSAGRVEANAGIECINCSVCYAACDTVAGNTDYLGPAALQRAWTLLNDA
CCCCCCEECCCCCCCEEECCCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
KDEGRVAILDAVSGSGGCHNCHSMGSCTAYCPNDLDPMSAIAGLKRETAKTWFRRGR
CCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]