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The map label for this gene is gap [H]

Identifier: 89056319

GI number: 89056319

Start: 3920883

End: 3921896

Strand: Direct

Name: gap [H]

Synonym: Jann_3828

Alternate gene names: 89056319

Gene position: 3920883-3921896 (Clockwise)

Preceding gene: 89056318

Following gene: 89056320

Centisome position: 90.8

GC content: 64.5

Gene sequence:

>1014_bases
ATGACACTTCGCGTGGCAATCAATGGCTTCGGGCGGATCGGGCGATCTGTTCTGCGGGCCTGGGTATTGGGCGGCGGGCG
GCTTGGACCGCACTGGCCGGAGATCCAGGTCGTGGCAATCAACGACATCGCCCCGGCAGAGACATGCGCTTATCTGTTTG
AGTTCGACAGCGTCTTTGGCGCGTTTCCAGGGTCAGTCACGGTGGAGAGCGCGGACCTGGTCGTCAACGGGCACCGGATA
ACGCTGAGCCAGGAACGGGACACGGGCGCTTTGGATTTGACGGGCGTCGACATTTTGATGGAGTGCACCGGGCGGGGGTC
CCGCGACGTGGCGGAGGCGGCGCTGACGGCTGGCGCGGGCCGTGTGCTGATCTCTGGCCCCGCGCCTGATCCGGATCTGA
CGATGGTCCTCGGCGCGAACCTTGAGGCACTCACGTCCCGGCACCGGATCGTGTCGAATGCATCGTGCACGACCAACGCG
ATCGCCCCGCTGGTGCGGTTGATTGACGAGGCTTGGGGCCTCGACAGCGCGCTGATGACAACGGTCCATTGCTACACGGG
ATCGCAACCGACCGTGGATATGCCAATGCGTGACCCGGCGCGGTCCCGTGCGGCAGCGCTGAGCATGGTGCCCACGACCA
CATCAGCGGAACCTCTGCTGGATATTGTACTGCCGGACCTGGCCGGTCTTGTGACCGGATCGGCGGTGCGCGTACCTGCG
GCTTCGGTCTCTTGCGTCGATCTGGCGGTGATGACGCGTGCAATGCCAAGCGCGGAGGAGGCGCGGACCCTCTTGCAAGG
GCGGGTGGACGGCGTCATTGGGTATACTGACAAACCTCTGGTCAGCTCCGACCTGAGGGCGCGGCCTGAGTCGCTGATCG
TGGCGGGGCCGGAGATCAAACGCTCCAAAGGCGGTATGTTGCGGGTCTTTGGGTGGTACGACAACGAATGGGGGTTCTCT
TGCCGGATGCTGGATGTGGCCCGGATCATGGGCACCCAGGCCGAAGGGGGTTAA

Upstream 100 bases:

>100_bases
ATGTTGAGGCCAATCACGAAAACCCATGGGACCATCCCGGCGCGTCCCTTGCGTGTGCCCGGGGGGTGTGCATCACTCGA
CCCGCAAGGGGGCGGCAACC

Downstream 100 bases:

>100_bases
TATGGCTGATTGGCAAGCATGGATGAAGGAAGCGGCGTTTGTGGACGGCGCTTGGGTAGGCGCGGACAGCGGCGAGACGA
TCGATGTGACGAACCCTGCC

Product: glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTLRVAINGFGRIGRSVLRAWVLGGGRLGPHWPEIQVVAINDIAPAETCAYLFEFDSVFGAFPGSVTVESADLVVNGHRI
TLSQERDTGALDLTGVDILMECTGRGSRDVAEAALTAGAGRVLISGPAPDPDLTMVLGANLEALTSRHRIVSNASCTTNA
IAPLVRLIDEAWGLDSALMTTVHCYTGSQPTVDMPMRDPARSRAAALSMVPTTTSAEPLLDIVLPDLAGLVTGSAVRVPA
ASVSCVDLAVMTRAMPSAEEARTLLQGRVDGVIGYTDKPLVSSDLRARPESLIVAGPEIKRSKGGMLRVFGWYDNEWGFS
CRMLDVARIMGTQAEGG

Sequences:

>Translated_337_residues
MTLRVAINGFGRIGRSVLRAWVLGGGRLGPHWPEIQVVAINDIAPAETCAYLFEFDSVFGAFPGSVTVESADLVVNGHRI
TLSQERDTGALDLTGVDILMECTGRGSRDVAEAALTAGAGRVLISGPAPDPDLTMVLGANLEALTSRHRIVSNASCTTNA
IAPLVRLIDEAWGLDSALMTTVHCYTGSQPTVDMPMRDPARSRAAALSMVPTTTSAEPLLDIVLPDLAGLVTGSAVRVPA
ASVSCVDLAVMTRAMPSAEEARTLLQGRVDGVIGYTDKPLVSSDLRARPESLIVAGPEIKRSKGGMLRVFGWYDNEWGFS
CRMLDVARIMGTQAEGG
>Mature_336_residues
TLRVAINGFGRIGRSVLRAWVLGGGRLGPHWPEIQVVAINDIAPAETCAYLFEFDSVFGAFPGSVTVESADLVVNGHRIT
LSQERDTGALDLTGVDILMECTGRGSRDVAEAALTAGAGRVLISGPAPDPDLTMVLGANLEALTSRHRIVSNASCTTNAI
APLVRLIDEAWGLDSALMTTVHCYTGSQPTVDMPMRDPARSRAAALSMVPTTTSAEPLLDIVLPDLAGLVTGSAVRVPAA
SVSCVDLAVMTRAMPSAEEARTLLQGRVDGVIGYTDKPLVSSDLRARPESLIVAGPEIKRSKGGMLRVFGWYDNEWGFSC
RMLDVARIMGTQAEGG

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=341, Percent_Identity=37.2434017595308, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI7657116, Length=339, Percent_Identity=38.3480825958702, Blast_Score=200, Evalue=1e-51,
Organism=Escherichia coli, GI1789295, Length=342, Percent_Identity=41.5204678362573, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI1788079, Length=334, Percent_Identity=38.9221556886228, Blast_Score=227, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17534677, Length=345, Percent_Identity=36.5217391304348, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17534679, Length=345, Percent_Identity=36.231884057971, Blast_Score=198, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI32566163, Length=346, Percent_Identity=36.4161849710983, Blast_Score=191, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17568413, Length=346, Percent_Identity=36.4161849710983, Blast_Score=191, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6321631, Length=333, Percent_Identity=38.4384384384384, Blast_Score=223, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6322468, Length=333, Percent_Identity=38.1381381381381, Blast_Score=223, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6322409, Length=333, Percent_Identity=36.3363363363363, Blast_Score=208, Evalue=1e-54,
Organism=Drosophila melanogaster, GI17933600, Length=339, Percent_Identity=38.3480825958702, Blast_Score=214, Evalue=6e-56,
Organism=Drosophila melanogaster, GI18110149, Length=339, Percent_Identity=38.3480825958702, Blast_Score=214, Evalue=6e-56,
Organism=Drosophila melanogaster, GI85725000, Length=339, Percent_Identity=37.7581120943953, Blast_Score=211, Evalue=7e-55,
Organism=Drosophila melanogaster, GI22023983, Length=339, Percent_Identity=37.7581120943953, Blast_Score=211, Evalue=7e-55,
Organism=Drosophila melanogaster, GI19922412, Length=333, Percent_Identity=34.2342342342342, Blast_Score=190, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35588; Mature: 35457

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRVAINGFGRIGRSVLRAWVLGGGRLGPHWPEIQVVAINDIAPAETCAYLFEFDSVFG
CEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
AFPGSVTVESADLVVNGHRITLSQERDTGALDLTGVDILMECTGRGSRDVAEAALTAGAG
CCCCCEEEECCEEEEECEEEEEECCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHCCCC
RVLISGPAPDPDLTMVLGANLEALTSRHRIVSNASCTTNAIAPLVRLIDEAWGLDSALMT
EEEEECCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
TVHCYTGSQPTVDMPMRDPARSRAAALSMVPTTTSAEPLLDIVLPDLAGLVTGSAVRVPA
EEEEECCCCCCEECCCCCCHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEECCC
ASVSCVDLAVMTRAMPSAEEARTLLQGRVDGVIGYTDKPLVSSDLRARPESLIVAGPEIK
CCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCEECCCCCCCCCCHHHCCCCEEEEECCCCC
RSKGGMLRVFGWYDNEWGFSCRMLDVARIMGTQAEGG
CCCCCEEEEEEEECCCCCCEEEHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TLRVAINGFGRIGRSVLRAWVLGGGRLGPHWPEIQVVAINDIAPAETCAYLFEFDSVFG
EEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
AFPGSVTVESADLVVNGHRITLSQERDTGALDLTGVDILMECTGRGSRDVAEAALTAGAG
CCCCCEEEECCEEEEECEEEEEECCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHCCCC
RVLISGPAPDPDLTMVLGANLEALTSRHRIVSNASCTTNAIAPLVRLIDEAWGLDSALMT
EEEEECCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
TVHCYTGSQPTVDMPMRDPARSRAAALSMVPTTTSAEPLLDIVLPDLAGLVTGSAVRVPA
EEEEECCCCCCEECCCCCCHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEECCC
ASVSCVDLAVMTRAMPSAEEARTLLQGRVDGVIGYTDKPLVSSDLRARPESLIVAGPEIK
CCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCEECCCCCCCCCCHHHCCCCEEEEECCCCC
RSKGGMLRVFGWYDNEWGFSCRMLDVARIMGTQAEGG
CCCCCEEEEEEEECCCCCCEEEHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7928974 [H]