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The map label for this gene is cocE [H]

Identifier: 89056305

GI number: 89056305

Start: 3902111

End: 3904063

Strand: Direct

Name: cocE [H]

Synonym: Jann_3814

Alternate gene names: 89056305

Gene position: 3902111-3904063 (Clockwise)

Preceding gene: 89056304

Following gene: 89056306

Centisome position: 90.37

GC content: 65.13

Gene sequence:

>1953_bases
ATGACCGACACGTTTGACGATATCCCCACTGTCTGGATCCCGATGCCCGATGGCGTGCGACTGGCCGCGCGCGTTTGGCT
GCCAAAGGGGCCGTCTGCGGCTGTGCTGGAATACCTCCCCTACCGTCGCCGCGACGGAACCTCGCTGCGCGACGCCTCCG
TTTATCCGGAGTTCGCGCGCATGGGTCTTGCGGGGGTGCGCGTCGACATACGCGGAACTGGCGATTCCGAAGGCCACTTT
GACGACGAATACTCAGAGCAGGAGCTGAGCGACGGGGAAGAGGTGATCAGGTGGATCGCTGCTCAACCTTGGTGCGACGG
CAACGTTGGCATGATGGGTATCTCCTGGGGCGGGTTCAATGCACTGCAACTGGCGGCCCGCAATCCACCCGCGTTGAAGG
CCGTGATTTCCATCGCCTCAACGGTGGACCGGTTCGCCGACGATATCCATTTCAAGGGCGGCGCGCATCTGTCGGCTAAT
CTTTACTGGGCCACGCAAATGCTCAGTCGCGCAGCCATGCCGCCGGATGCGGCCGTCGTGGGCGAAGGCTGGCGGACGCA
GTGGAAAGACCGGCTGGCGCATTTGCCCGCCCTGATCTTCCCCTGGATGGCGCATCAGCGCCGCGATGATTACTGGAAGC
ACGGCTCCATCTGTGAGGATTTCGGCGCGGTTGAGGCCCCGGCCATGATGATCGCCGGATGGGCCGACGGGTACCGCAAC
ACGCCGTGGGACGCACGGGAAGGCATCGGCAACGAAGCACGGTCGATCACCGGGCCATGGGTGCATCTTTACCCGCATTT
CGCGGTGCCGGAGCCTCGGTTGGACTTTGTCGGAGAGGCCGCACGCTGGTGGGGTCGATGGCTGCAAGACAAGGACACCG
GCGCGGAGGCATTGCCCGACCACCGGCTGTATCTGTCCGAGGCCGTCCGCCCGGACCAGACCCGCGCCCATGACCCGGGC
CGCTGGATCGAGATCACACAGGGCGAAGAGACGGAGACGGTCCTGCGCCTGTCCCCTGGCACCCTTGGTGCGACGGGTAG
CGGCCAGGTGACGGTCCGGACGCCGCTGGATTGCGGCACCGATGCAGGAGAATTCTTCACCCAGGGGGCGGATACCGACC
TGCCCGATGATCAGCGCGCCGATGACGGCATGTCGGTGTGTTTTGAAACCGCGCCCTTAACCACCCCGCTCGACATCATT
GGCCGCCCGACCCTGCACGTGCCCGTCACGATCGATGCGCCTCAGGGCACCCTGATCGCACGGCTTGTGGATGTGCATCC
CGATGGCACGTCCCACCGTATCAGCCTTGGCGTCCTGAACCTGTCTCATCGGAATGGCTCGGAGAGCCCCGCTGCGATGA
CACCCGGCAGGGTGGAGGAGGTGCGCGTGATCCTGGACGCGACAGCCTACAGGATCCGCCCCGGGCACAGGTTGCGGCTG
GCCATCTCCACCGCGTATTTCCCCATGATCGTGCCACCACCCACGGACGTCACCGCCACGCTATCGCTGGACACCGCGGC
GCTTCATCTACCCTCCACCCCCTACACCGAAATCAATCTGCCGCAGGCGGGGCAAGACACGCGGCCGACCTTCCCAACCA
CCCCCGGCTCTGTCGCGCGCCGTGTCAACCGCGACCGCGCCAGCGGCACCACCTCCGTGACCATCGAGAGCGACAGCGGC
ACCACGACCCACCCGGATTACGGCATCGCCTGGCGTGATGTTCGGCGCTCTGACTATACGATCACCCGGGGCGATCCGCT
CAGCTATCGCGCGGTGGAGGTCTCGACGCACGAGAGGACCCGTGACGGCATACTCACCCGCGTCATTGCCACGGGCCGCC
TGCGCGCCACGGAAACCGATTGGATCATCGACGCCCGCATTGAAGCGACGGAGGATGATCAACCTTTTTTCAGCCGCGAT
TGGTCCCGGACCATCGCACGCGATCACATGTGA

Upstream 100 bases:

>100_bases
CAAAACATTCGTGTGGATGGCGGGATCACGCGGTCGGTTTGACACGTTGAATGTCGCGCAACGCCCTTGACCCGCCCTGA
AAATCCAGCGCGGATAGCAT

Downstream 100 bases:

>100_bases
TCTGCCATGACCCGCCCAAAGCACCGGATCGCCATCGCCGGGTTTCAGCACGAAACCAACAGCTTTTCGCCCACACCCGC
GACCCTTGCGGATTTTGAAA

Product: peptidase S15

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 650; Mature: 649

Protein sequence:

>650_residues
MTDTFDDIPTVWIPMPDGVRLAARVWLPKGPSAAVLEYLPYRRRDGTSLRDASVYPEFARMGLAGVRVDIRGTGDSEGHF
DDEYSEQELSDGEEVIRWIAAQPWCDGNVGMMGISWGGFNALQLAARNPPALKAVISIASTVDRFADDIHFKGGAHLSAN
LYWATQMLSRAAMPPDAAVVGEGWRTQWKDRLAHLPALIFPWMAHQRRDDYWKHGSICEDFGAVEAPAMMIAGWADGYRN
TPWDAREGIGNEARSITGPWVHLYPHFAVPEPRLDFVGEAARWWGRWLQDKDTGAEALPDHRLYLSEAVRPDQTRAHDPG
RWIEITQGEETETVLRLSPGTLGATGSGQVTVRTPLDCGTDAGEFFTQGADTDLPDDQRADDGMSVCFETAPLTTPLDII
GRPTLHVPVTIDAPQGTLIARLVDVHPDGTSHRISLGVLNLSHRNGSESPAAMTPGRVEEVRVILDATAYRIRPGHRLRL
AISTAYFPMIVPPPTDVTATLSLDTAALHLPSTPYTEINLPQAGQDTRPTFPTTPGSVARRVNRDRASGTTSVTIESDSG
TTTHPDYGIAWRDVRRSDYTITRGDPLSYRAVEVSTHERTRDGILTRVIATGRLRATETDWIIDARIEATEDDQPFFSRD
WSRTIARDHM

Sequences:

>Translated_650_residues
MTDTFDDIPTVWIPMPDGVRLAARVWLPKGPSAAVLEYLPYRRRDGTSLRDASVYPEFARMGLAGVRVDIRGTGDSEGHF
DDEYSEQELSDGEEVIRWIAAQPWCDGNVGMMGISWGGFNALQLAARNPPALKAVISIASTVDRFADDIHFKGGAHLSAN
LYWATQMLSRAAMPPDAAVVGEGWRTQWKDRLAHLPALIFPWMAHQRRDDYWKHGSICEDFGAVEAPAMMIAGWADGYRN
TPWDAREGIGNEARSITGPWVHLYPHFAVPEPRLDFVGEAARWWGRWLQDKDTGAEALPDHRLYLSEAVRPDQTRAHDPG
RWIEITQGEETETVLRLSPGTLGATGSGQVTVRTPLDCGTDAGEFFTQGADTDLPDDQRADDGMSVCFETAPLTTPLDII
GRPTLHVPVTIDAPQGTLIARLVDVHPDGTSHRISLGVLNLSHRNGSESPAAMTPGRVEEVRVILDATAYRIRPGHRLRL
AISTAYFPMIVPPPTDVTATLSLDTAALHLPSTPYTEINLPQAGQDTRPTFPTTPGSVARRVNRDRASGTTSVTIESDSG
TTTHPDYGIAWRDVRRSDYTITRGDPLSYRAVEVSTHERTRDGILTRVIATGRLRATETDWIIDARIEATEDDQPFFSRD
WSRTIARDHM
>Mature_649_residues
TDTFDDIPTVWIPMPDGVRLAARVWLPKGPSAAVLEYLPYRRRDGTSLRDASVYPEFARMGLAGVRVDIRGTGDSEGHFD
DEYSEQELSDGEEVIRWIAAQPWCDGNVGMMGISWGGFNALQLAARNPPALKAVISIASTVDRFADDIHFKGGAHLSANL
YWATQMLSRAAMPPDAAVVGEGWRTQWKDRLAHLPALIFPWMAHQRRDDYWKHGSICEDFGAVEAPAMMIAGWADGYRNT
PWDAREGIGNEARSITGPWVHLYPHFAVPEPRLDFVGEAARWWGRWLQDKDTGAEALPDHRLYLSEAVRPDQTRAHDPGR
WIEITQGEETETVLRLSPGTLGATGSGQVTVRTPLDCGTDAGEFFTQGADTDLPDDQRADDGMSVCFETAPLTTPLDIIG
RPTLHVPVTIDAPQGTLIARLVDVHPDGTSHRISLGVLNLSHRNGSESPAAMTPGRVEEVRVILDATAYRIRPGHRLRLA
ISTAYFPMIVPPPTDVTATLSLDTAALHLPSTPYTEINLPQAGQDTRPTFPTTPGSVARRVNRDRASGTTSVTIESDSGT
TTHPDYGIAWRDVRRSDYTITRGDPLSYRAVEVSTHERTRDGILTRVIATGRLRATETDWIIDARIEATEDDQPFFSRDW
SRTIARDHM

Specific function: Hydrolyzes cocaine to benzoate and ecgonine methyl ester, endowing the bacteria with the ability to utilize cocaine as a sole source of carbon and energy for growth, as this bacterium lives in the rhizosphere of coca plants [H]

COG id: COG2936

COG function: function code R; Predicted acyl esterases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha/beta hydrolase family. Carboxylesterase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005674
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR000383 [H]

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C [H]

EC number: NA

Molecular weight: Translated: 71864; Mature: 71733

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00032 ANTENNAPEDIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTFDDIPTVWIPMPDGVRLAARVWLPKGPSAAVLEYLPYRRRDGTSLRDASVYPEFAR
CCCCCCCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHH
MGLAGVRVDIRGTGDSEGHFDDEYSEQELSDGEEVIRWIAAQPWCDGNVGMMGISWGGFN
CCCEEEEEEEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCCCCCCCEEEEECCCCC
ALQLAARNPPALKAVISIASTVDRFADDIHFKGGAHLSANLYWATQMLSRAAMPPDAAVV
EEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHCCCCCCEEE
GEGWRTQWKDRLAHLPALIFPWMAHQRRDDYWKHGSICEDFGAVEAPAMMIAGWADGYRN
CCCHHHHHHHHHHHCHHHHHHHHHHHCCCCHHCCCCHHHHCCCCCCCCEEEEECCCCCCC
TPWDAREGIGNEARSITGPWVHLYPHFAVPEPRLDFVGEAARWWGRWLQDKDTGAEALPD
CCCHHHHCCCCCHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
HRLYLSEAVRPDQTRAHDPGRWIEITQGEETETVLRLSPGTLGATGSGQVTVRTPLDCGT
CHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCC
DAGEFFTQGADTDLPDDQRADDGMSVCFETAPLTTPLDIIGRPTLHVPVTIDAPQGTLIA
CHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHCCCEEEEEEEEECCCCCEEE
RLVDVHPDGTSHRISLGVLNLSHRNGSESPAAMTPGRVEEVRVILDATAYRIRPGHRLRL
EEEEECCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHEEEEEECCEEEECCCCEEEE
AISTAYFPMIVPPPTDVTATLSLDTAALHLPSTPYTEINLPQAGQDTRPTFPTTPGSVAR
EEEECCCEEEECCCCCEEEEEEECEEEEECCCCCCCEEECCCCCCCCCCCCCCCCHHHHH
RVNRDRASGTTSVTIESDSGTTTHPDYGIAWRDVRRSDYTITRGDPLSYRAVEVSTHERT
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHCCCCCEEEECCCCCCEEEEEECCCHHH
RDGILTRVIATGRLRATETDWIIDARIEATEDDQPFFSRDWSRTIARDHM
HHHHHHHHHHCCCEEECCCCEEEEEEEECCCCCCCHHHCCHHHHHHHCCC
>Mature Secondary Structure 
TDTFDDIPTVWIPMPDGVRLAARVWLPKGPSAAVLEYLPYRRRDGTSLRDASVYPEFAR
CCCCCCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHH
MGLAGVRVDIRGTGDSEGHFDDEYSEQELSDGEEVIRWIAAQPWCDGNVGMMGISWGGFN
CCCEEEEEEEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCCCCCCCEEEEECCCCC
ALQLAARNPPALKAVISIASTVDRFADDIHFKGGAHLSANLYWATQMLSRAAMPPDAAVV
EEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHCCCCCCEEE
GEGWRTQWKDRLAHLPALIFPWMAHQRRDDYWKHGSICEDFGAVEAPAMMIAGWADGYRN
CCCHHHHHHHHHHHCHHHHHHHHHHHCCCCHHCCCCHHHHCCCCCCCCEEEEECCCCCCC
TPWDAREGIGNEARSITGPWVHLYPHFAVPEPRLDFVGEAARWWGRWLQDKDTGAEALPD
CCCHHHHCCCCCHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
HRLYLSEAVRPDQTRAHDPGRWIEITQGEETETVLRLSPGTLGATGSGQVTVRTPLDCGT
CHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCC
DAGEFFTQGADTDLPDDQRADDGMSVCFETAPLTTPLDIIGRPTLHVPVTIDAPQGTLIA
CHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHCCCEEEEEEEEECCCCCEEE
RLVDVHPDGTSHRISLGVLNLSHRNGSESPAAMTPGRVEEVRVILDATAYRIRPGHRLRL
EEEEECCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHEEEEEECCEEEECCCCEEEE
AISTAYFPMIVPPPTDVTATLSLDTAALHLPSTPYTEINLPQAGQDTRPTFPTTPGSVAR
EEEECCCEEEECCCCCEEEEEEECEEEEECCCCCCCEEECCCCCCCCCCCCCCCCHHHHH
RVNRDRASGTTSVTIESDSGTTTHPDYGIAWRDVRRSDYTITRGDPLSYRAVEVSTHERT
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHCCCCCEEEECCCCCCEEEEEECCCHHH
RDGILTRVIATGRLRATETDWIIDARIEATEDDQPFFSRDWSRTIARDHM
HHHHHHHHHHCCCEEECCCCEEEEEEEECCCCCCCHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10698749; 11742345; 12369817 [H]