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The map label for this gene is murQ

Identifier: 89056294

GI number: 89056294

Start: 3888386

End: 3889336

Strand: Direct

Name: murQ

Synonym: Jann_3803

Alternate gene names: 89056294

Gene position: 3888386-3889336 (Clockwise)

Preceding gene: 89056291

Following gene: 89056295

Centisome position: 90.05

GC content: 60.99

Gene sequence:

>951_bases
ATGGGAGTCGCTGCCGTGTTTACCGCCGTCCAGTCAGATCTTGGGGCACTTGTGTCCGAGGCGAGCAATTCGCGCTCTGC
GGACATTGATCTGATGACCACAGCCCAGATCCTGGCCTGCATGAACGCCGAGGATCGTAAAATCGCCGATGCCGTCGCAG
CAGAGCTTCCCGCGATTGCCCAGACTGTTGACAGGATCGTCGCAGCGATTGGCCGTGGCGGGCGCCTTATCTACATCGGT
GCGGGCACCAGCGGTCGTTTGGGCGTATTGGATGCATCTGAATGCCCGCCCACGTTTTCCGTCCCTCCCGGCATGGTGGT
TGGCCTGATCGCCGGTGGCGACACAGCGCTGCGCACCTCGGTTGAGGCGGCCGAAGATGATGAGGCAACGGGTGCGGAGG
ACGTGAAAGCCATCGGGCTGACAACCAAAGATGTCGTCATCGGTATCGCGGTCAGTGGCAGAACCCCCTTCGTGATGGGC
GCGATAGACTACGCCCGCCGCATTGGCGCGTTCACTGCCGCGCTGACCTGCAACCCAGGCTCGCCCATGGCGGACCTTGC
TGACATCGCGATCTCACCCGTTGTCGGGCCGGAGGTTGTGACCGGCTCCACGCGCCTCAAATCCGGGACCGCGCAAAAAA
TGATCCTGAACATGCTGAGCACCGCCAGCATGATCCGCCTTGGTAAGACATGGGGCAACCGGATGGTGGATGTGACGATT
TCAAATCGGAAATTGGCGGACCGCGCCACTGCCATGTTGCGGGATGCCACCGGGTGCAGCGCCGATGATGCGCGTACTTT
GCTGGACCAAAGCAATGGCAGCGTGAAACTTGCCATCCTGATGCAGATTACGGGCTGTGACGCAGATGCGGCCCGCGCAA
ATCTGGAGGCTGAAAACGGCTTCCTGCGCAAAGCCATTGAACGAGCGGAGAAAACTCCGCCGCAAAGCTAG

Upstream 100 bases:

>100_bases
TGAGTATGGACAAGAGTTTTCCATGGCATTTGGGCGGTTTGGAATAATCTACCACACAAAGTTTGACATGTGTGAATAAA
AAATTCATATTGGTGGGTGA

Downstream 100 bases:

>100_bases
AGTAATTCACACAAACTGGGAGATAACTGGAATGACCTCGATCAAAACAACCGCCCGCGCGCTGGCACTCATAAGCACCG
CCCTCGCGGCCCCATTGTCC

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MGVAAVFTAVQSDLGALVSEASNSRSADIDLMTTAQILACMNAEDRKIADAVAAELPAIAQTVDRIVAAIGRGGRLIYIG
AGTSGRLGVLDASECPPTFSVPPGMVVGLIAGGDTALRTSVEAAEDDEATGAEDVKAIGLTTKDVVIGIAVSGRTPFVMG
AIDYARRIGAFTAALTCNPGSPMADLADIAISPVVGPEVVTGSTRLKSGTAQKMILNMLSTASMIRLGKTWGNRMVDVTI
SNRKLADRATAMLRDATGCSADDARTLLDQSNGSVKLAILMQITGCDADAARANLEAENGFLRKAIERAEKTPPQS

Sequences:

>Translated_316_residues
MGVAAVFTAVQSDLGALVSEASNSRSADIDLMTTAQILACMNAEDRKIADAVAAELPAIAQTVDRIVAAIGRGGRLIYIG
AGTSGRLGVLDASECPPTFSVPPGMVVGLIAGGDTALRTSVEAAEDDEATGAEDVKAIGLTTKDVVIGIAVSGRTPFVMG
AIDYARRIGAFTAALTCNPGSPMADLADIAISPVVGPEVVTGSTRLKSGTAQKMILNMLSTASMIRLGKTWGNRMVDVTI
SNRKLADRATAMLRDATGCSADDARTLLDQSNGSVKLAILMQITGCDADAARANLEAENGFLRKAIERAEKTPPQS
>Mature_315_residues
GVAAVFTAVQSDLGALVSEASNSRSADIDLMTTAQILACMNAEDRKIADAVAAELPAIAQTVDRIVAAIGRGGRLIYIGA
GTSGRLGVLDASECPPTFSVPPGMVVGLIAGGDTALRTSVEAAEDDEATGAEDVKAIGLTTKDVVIGIAVSGRTPFVMGA
IDYARRIGAFTAALTCNPGSPMADLADIAISPVVGPEVVTGSTRLKSGTAQKMILNMLSTASMIRLGKTWGNRMVDVTIS
NRKLADRATAMLRDATGCSADDARTLLDQSNGSVKLAILMQITGCDADAARANLEAENGFLRKAIERAEKTPPQS

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=292, Percent_Identity=50.3424657534247, Blast_Score=303, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_JANSC (Q28KP2)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_511745.1
- ProteinModelPortal:   Q28KP2
- SMR:   Q28KP2
- STRING:   Q28KP2
- GeneID:   3936283
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_3803
- eggNOG:   COG2103
- HOGENOM:   HBG703490
- OMA:   SMIGVGK
- PhylomeDB:   Q28KP2
- ProtClustDB:   PRK12570
- BioCyc:   JSP290400:JANN_3803-MONOMER
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00274

Pfam domain/function: PF01380 SIS

EC number: NA

Molecular weight: Translated: 32511; Mature: 32379

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 94-94 ACT_SITE 125-125

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVAAVFTAVQSDLGALVSEASNSRSADIDLMTTAQILACMNAEDRKIADAVAAELPAIA
CCHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
QTVDRIVAAIGRGGRLIYIGAGTSGRLGVLDASECPPTFSVPPGMVVGLIAGGDTALRTS
HHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCHHHHHC
VEAAEDDEATGAEDVKAIGLTTKDVVIGIAVSGRTPFVMGAIDYARRIGAFTAALTCNPG
CCCCCCCCCCCHHHHHEECCEECCEEEEEEECCCCCEEEHHHHHHHHHHCEEEEEEECCC
SPMADLADIAISPVVGPEVVTGSTRLKSGTAQKMILNMLSTASMIRLGKTWGNRMVDVTI
CCHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
SNRKLADRATAMLRDATGCSADDARTLLDQSNGSVKLAILMQITGCDADAARANLEAENG
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEEEEEECCCCHHHHCCCCCCCC
FLRKAIERAEKTPPQS
HHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GVAAVFTAVQSDLGALVSEASNSRSADIDLMTTAQILACMNAEDRKIADAVAAELPAIA
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
QTVDRIVAAIGRGGRLIYIGAGTSGRLGVLDASECPPTFSVPPGMVVGLIAGGDTALRTS
HHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCHHHHHC
VEAAEDDEATGAEDVKAIGLTTKDVVIGIAVSGRTPFVMGAIDYARRIGAFTAALTCNPG
CCCCCCCCCCCHHHHHEECCEECCEEEEEEECCCCCEEEHHHHHHHHHHCEEEEEEECCC
SPMADLADIAISPVVGPEVVTGSTRLKSGTAQKMILNMLSTASMIRLGKTWGNRMVDVTI
CCHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
SNRKLADRATAMLRDATGCSADDARTLLDQSNGSVKLAILMQITGCDADAARANLEAENG
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEEEEEECCCCHHHHCCCCCCCC
FLRKAIERAEKTPPQS
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA