Click here to switch to the map view.

The map label for this gene is apxIIIA [H]

Identifier: 89056172

GI number: 89056172

Start: 3759200

End: 3763588

Strand: Direct

Name: apxIIIA [H]

Synonym: Jann_3681

Alternate gene names: 89056172

Gene position: 3759200-3763588 (Clockwise)

Preceding gene: 89056171

Following gene: 89056177

Centisome position: 87.06

GC content: 62.0

Gene sequence:

>4389_bases
ATGGCTACGATTAACGGTGACGGTACAGACAACACTCTGACCGGCACAGGCGCCGCCGATGACATTACCGGCTTTGCAGG
CAATGACACGATAACAGGCGGCAACGGCAACGACGCGATTGATGGCGGTGCGCCCTCCCTCACGCCCACGGCGCTGGACT
TGAACTGGACCGCCCAGGGCGGAAACGGCACCAATCTGGCCGGTGGCTTTACCCAAAATACCGGCGGCATCGATGTGGCC
GTCAGCTTCACCAATGACGGCGGCGGCAGTGCCGCACAGGTCAGCACAAGCACGACCTTTGTCGATACTGGCGAAACCTA
CGACGCGAACTCCAACCTTTCGATGACCGGCAATGGCGGATCCGATGTCTGGACCGTGGATGTCGATTTTTCTTCCGTAG
GGGGCTCGGGCTTCGCTGATGAGGTCGAGAACGTCGCCTTCCGCCTGCAAGATATCGACACCGGCGGTTGGCAGGACATC
GTGACCGTCAATGCTTACGATGCCGACGGCAACCTGATCCCTGTCATCCTGACGCCATCGGGCGGCGATACCGTTAGCGG
CAATACCGTGACAGCGGGTCCCGGGGCGACCGCGGCCAGCTCTTCTGAAGGCTCTGTCCTTGTGGAAATCGCGGGCCCTG
TCGCGCGGTTCGAGATCATCTACCAAAATGGCGGGACGTCTGGACAGCTTGGCCTTGTCACCGATGTTCAATTCGACGCG
GTCCCCACAGATGACGATGAGCTGTTCGGTGAGGCTGGCAACGACACGATCACGGGCGGGTTTGGCGACGACCTTCTGGA
TGGAGGCACCAATAATGACGTGCTCGACGGCGGGTCAGGCAATGACACGCTGATCGGCGGCTCGGGCAACGACACGCTGG
ACGGTGGCGCAGGACAAGACAGTCTTGAGGGCGGCACCGGCGCGGATGTCCTGACCGGTGGCGATGGCAACGATACGTTG
GGTGGCGGTGGCGGAGCAGACACGCTGGATGGTGGCGACGGCGACGACAGCCTGTCTGGCGGCAGCGGGTTCGACGTTCT
CACCGGTGGCGAAGGGGCCGATACGCTGGACGGCGGCAACGGCAACGACATTTTTAATGCAGGCAGCGGCGACGTCGTCA
TTGGCGGCGAAGGTGGCACGGACACCAACGACCAGCTGATCGTCGATGATGTGGCCGAGGTCATCTTCGACCCGCTCAAT
TCTGAAAACGGCACGGTTGTCTTCAACGACGGGTCCACCGCGACATTCACGGGGATTGAAACACTGGTCGTGAACGGCGG
GCCTGACGGCGTCGTGGACGGAACCTTCGGTAACGACGTGATCGACAGCGATTACGTCGATCCGAACCTTGAGCAGGTGG
ACAATGGCGACGGCACCCTTGGCACCGCCGGGGACGAAGACGTCATCGAGGCGGGGTTCGGCGACGACACCGTTTACGCA
GGCGAAGGCAACGACAGCATCGAGGGCGGGCCGAGCGGTCCGTTGAACTCGGCCACTGAAAACTTCAGCTGGATCGCGGA
AGGTGACGGCACCGATATCTCTGGCGGGATCACGCAAGACACGGGCGTGGCCAATATCACGGTGGGCATAACCAACGACG
GCGCTCTGAACCAATCTGCGATCACCAACACCACGCAATATGTGGACGGGGCAGACCCGTTCTCGGCCACCTCCGGTCTC
GCGCTTGGTGGAAGTGGTGGCGCGGATGTGGCGACGCTCGACTTCGCCGCAGATGCAGAACTGACGGGTGTGTCCTTCCG
CCTGAACGACATCGACGCGGGGGCTTGGGAAGATATCGTGACGGTCAATGCCTATGACCCGAACGGCAATCTGGTGCCCG
TCGTCCTGACGCCCGAAACAGCGGGCGACGTGGTCACGGGCCAGACCGTCACCGGTGCCGGGACCGATAATCCCAATCAA
ATCGGCGGGTCAGTTCTGGTGGAAATTGCCGGGCCCATCACCCGGTTTGAGGTCATCTACGAGAACGGCAGCACCGGCGG
GCAGGTCGTCTATCTGACGGATATCCACTACACCGCGTCCGAAACGGACGATGATGTCCTGCATGGCGACCAAGGTGGGG
ACACCATCGACGGCGGCGCGGGCAATGATGTGATCTTCGGCGATCAAATGGCCGTCGATCCCGCTGATATCCCGTCGGGC
ACCGGCGGCACGGCGACATCGGCCACATTCCAGAACGACAGCCCCTACGCGGTCGGGCTGGCGCAGGTCGATGCGTCGGG
CGTGGTGGTTCCGGTGATCACGATCCCCGCAGGCAGCGACTATACCGCGCCGTCCACGACCCAGACCAACTGGGTCCTTC
TGGAACCGGCCACAGGCGACATCCTTCAGGTCTATGAAGCCCCCGCCGACGGCAGCACGCTCATCTTCGACAGTTCCGGA
GCCGACAGCCTGTTTGGAGGCTTGGGCGATGACACAATCTCGGGCGATTTTGGCAATGACACGATAGACGGCGGGGCGGG
CGACGACAGCCTCAGTGGCGGGGCCGAGCAGGACGTGTTCCAGTTTACCGATGGCTTTGGCACCGACACCGTCGATGGCG
GTGAGGCCGGGGACGATCTCGACACGCTCGACTTCAGCCAGATGACGACGGGCATCGACGTCATGTTCGATGGCGACGAG
CAGGGCGATGTGTCTGATACAGGCTCTACCGACAGCGTTGAATTCACCAATATTGAACGGGTCGATGGCACGGGTCAGGA
CGACACGATTGACGCGGGCGCGTCCAACGCAGATCAAACGCTGATTGGCAACGACGGCGCGGACAGCATTGTGGGCGGGT
CCGGCAACGATACGCTCTACGGCGATGGTGGCACCAGCACGCCCGCAAATGGCACATTGATCTATGCCGATAATTTCGAT
GGCGGCAATGACGGCGGCTGGGGCAGCACACCCACCGACAACACAGACCCGTTCTTCGGCTCCGTGCTCGGGCGCGTTCA
GGGCACGGCGTCCAGCACCGATATCGAAGCGCAACGCACGCTGACATTTGATCCCGCCTATGACGATGCGGTCATCGAGT
TTGACTTCCACCGCATCGACAGCTGGGACAATGAAGACTTCCAGATCTATGCCAACGGGCAGGAGATCTTTAGCCAGACC
TTCAATCCCGGCACGATTGTCGGCGGGGCCAACACCGTCACAATCGGCGGCGTCACCTATACGATCACGCTGACATCGCA
AGGCGATGCGGCGCAGAACGGGTATTGGGATGGCCAACCCTGGACCACGGACCAAAGCTTCCGCGTCCGGATCGAAGTTG
AAAACGCCCCCGAGACGCTGGATCTGGGGTTTGGCTCCACGATCAACCAAGCAGTCACCGACGAAAGTTACGCGTTCGAC
AATTTCGCCGTCGTGTCCACGAACGACACGTCCATCGACCCAACCGACTTCATCAACACCGGCAACGACGACACCATCGA
AGGCGGCGCGGGCAACGATGAAATCTACGGAGAAGAGGGCAATGATGTCCTCGACGGCGGCGCGGATAACGACACGCTCT
TTGGCGGCGACGGCGATGACAGCGTTCAGGGCGGGGCGGGTCAGGACAGCCTGATCGGTGGCCAGGGCAACGACACACTT
GTGGGCGGGGACGACGCGGACTGGATTTTCGGTGGCTCTGGCGATGTCATCGATGGCGGTGAAGGCGGCGACGACAACGA
TACGCTCTTCCTTGGCGATGACGGGGCCATCATCGTCTACGACACCGTTAACCCGGAAAACGGCACCGTTACCTTCAGCG
ACGGCACCACGCTGACATTCCAGAATATCGAAACGGTCATTCCCTGTTTCACCCCCGGCTGCCGCGTCGCAACCGCACGT
GGCACGTCAAAGGTCGAAGACCTGCGCGTCGGTGATCTGATCGAGACCCATGACAATGGCTTGCAGGCCGTCCGCTGGAT
CGGAGCGAAGACGCTGACCCAAATCGATCTGGCCCGCGCGCCGCATCTGCGGCCCATCCGCATTCGCACGGGGGCCTTGG
GACCGGGCGTGCCGAACCGGGATATGGAGGTCTCTCCCCAGCATCGCATGTTGATAGAGGGGGGGCAGACGGAACTGCTG
TTCGGCGAAGATCAGGTGCTGGTGCGCGCCAAGCATCTGACGCATCTGCCGGGTGTAGAGGTCGTGAAAACCTGTGAGCG
GGTCACCTACATCCACGTCATGTGCGACGCCCATGAGGTGATCCGCGTCGACGATGCCTGGACCGAGAGTTTCCAGCCCG
GCGATCTGGTGCAGGATCACGAGGCGCGGGAGATCTTTGGCGATCTGCTGCACGCCTTCCCCGGGTTGGGCACGGAGGCG
GGGCGCGAAACCTACGTCTCTGCCCGGCTCAGCCTGAAAGCCCATGAGGCCGGGTTGGTCCGGATCTAG

Upstream 100 bases:

>100_bases
CTTTGTGTTGCCTCAATTGGCCTCAGTTTCGTCATGTCGCCATGACTACTTTTCGCAAGTTTGAGCAATCGGCCGCAGAG
CCGGAACGAGTGGAAGAAAC

Downstream 100 bases:

>100_bases
ACCTGCCGCAGCGGCACCTCGCGCCCATTGGCAAGTGCCGGGATCTGCCCCCGCACCTTGGCGCATTGGGCAAGGTCCAG
CGTAACCACTTGCACCTTTG

Product: hemolysin-type calcium-binding protein

Products: NA

Alternate protein names: APX-IIIA; Cytolysin IIIA; CLY-IIIA [H]

Number of amino acids: Translated: 1462; Mature: 1461

Protein sequence:

>1462_residues
MATINGDGTDNTLTGTGAADDITGFAGNDTITGGNGNDAIDGGAPSLTPTALDLNWTAQGGNGTNLAGGFTQNTGGIDVA
VSFTNDGGGSAAQVSTSTTFVDTGETYDANSNLSMTGNGGSDVWTVDVDFSSVGGSGFADEVENVAFRLQDIDTGGWQDI
VTVNAYDADGNLIPVILTPSGGDTVSGNTVTAGPGATAASSSEGSVLVEIAGPVARFEIIYQNGGTSGQLGLVTDVQFDA
VPTDDDELFGEAGNDTITGGFGDDLLDGGTNNDVLDGGSGNDTLIGGSGNDTLDGGAGQDSLEGGTGADVLTGGDGNDTL
GGGGGADTLDGGDGDDSLSGGSGFDVLTGGEGADTLDGGNGNDIFNAGSGDVVIGGEGGTDTNDQLIVDDVAEVIFDPLN
SENGTVVFNDGSTATFTGIETLVVNGGPDGVVDGTFGNDVIDSDYVDPNLEQVDNGDGTLGTAGDEDVIEAGFGDDTVYA
GEGNDSIEGGPSGPLNSATENFSWIAEGDGTDISGGITQDTGVANITVGITNDGALNQSAITNTTQYVDGADPFSATSGL
ALGGSGGADVATLDFAADAELTGVSFRLNDIDAGAWEDIVTVNAYDPNGNLVPVVLTPETAGDVVTGQTVTGAGTDNPNQ
IGGSVLVEIAGPITRFEVIYENGSTGGQVVYLTDIHYTASETDDDVLHGDQGGDTIDGGAGNDVIFGDQMAVDPADIPSG
TGGTATSATFQNDSPYAVGLAQVDASGVVVPVITIPAGSDYTAPSTTQTNWVLLEPATGDILQVYEAPADGSTLIFDSSG
ADSLFGGLGDDTISGDFGNDTIDGGAGDDSLSGGAEQDVFQFTDGFGTDTVDGGEAGDDLDTLDFSQMTTGIDVMFDGDE
QGDVSDTGSTDSVEFTNIERVDGTGQDDTIDAGASNADQTLIGNDGADSIVGGSGNDTLYGDGGTSTPANGTLIYADNFD
GGNDGGWGSTPTDNTDPFFGSVLGRVQGTASSTDIEAQRTLTFDPAYDDAVIEFDFHRIDSWDNEDFQIYANGQEIFSQT
FNPGTIVGGANTVTIGGVTYTITLTSQGDAAQNGYWDGQPWTTDQSFRVRIEVENAPETLDLGFGSTINQAVTDESYAFD
NFAVVSTNDTSIDPTDFINTGNDDTIEGGAGNDEIYGEEGNDVLDGGADNDTLFGGDGDDSVQGGAGQDSLIGGQGNDTL
VGGDDADWIFGGSGDVIDGGEGGDDNDTLFLGDDGAIIVYDTVNPENGTVTFSDGTTLTFQNIETVIPCFTPGCRVATAR
GTSKVEDLRVGDLIETHDNGLQAVRWIGAKTLTQIDLARAPHLRPIRIRTGALGPGVPNRDMEVSPQHRMLIEGGQTELL
FGEDQVLVRAKHLTHLPGVEVVKTCERVTYIHVMCDAHEVIRVDDAWTESFQPGDLVQDHEAREIFGDLLHAFPGLGTEA
GRETYVSARLSLKAHEAGLVRI

Sequences:

>Translated_1462_residues
MATINGDGTDNTLTGTGAADDITGFAGNDTITGGNGNDAIDGGAPSLTPTALDLNWTAQGGNGTNLAGGFTQNTGGIDVA
VSFTNDGGGSAAQVSTSTTFVDTGETYDANSNLSMTGNGGSDVWTVDVDFSSVGGSGFADEVENVAFRLQDIDTGGWQDI
VTVNAYDADGNLIPVILTPSGGDTVSGNTVTAGPGATAASSSEGSVLVEIAGPVARFEIIYQNGGTSGQLGLVTDVQFDA
VPTDDDELFGEAGNDTITGGFGDDLLDGGTNNDVLDGGSGNDTLIGGSGNDTLDGGAGQDSLEGGTGADVLTGGDGNDTL
GGGGGADTLDGGDGDDSLSGGSGFDVLTGGEGADTLDGGNGNDIFNAGSGDVVIGGEGGTDTNDQLIVDDVAEVIFDPLN
SENGTVVFNDGSTATFTGIETLVVNGGPDGVVDGTFGNDVIDSDYVDPNLEQVDNGDGTLGTAGDEDVIEAGFGDDTVYA
GEGNDSIEGGPSGPLNSATENFSWIAEGDGTDISGGITQDTGVANITVGITNDGALNQSAITNTTQYVDGADPFSATSGL
ALGGSGGADVATLDFAADAELTGVSFRLNDIDAGAWEDIVTVNAYDPNGNLVPVVLTPETAGDVVTGQTVTGAGTDNPNQ
IGGSVLVEIAGPITRFEVIYENGSTGGQVVYLTDIHYTASETDDDVLHGDQGGDTIDGGAGNDVIFGDQMAVDPADIPSG
TGGTATSATFQNDSPYAVGLAQVDASGVVVPVITIPAGSDYTAPSTTQTNWVLLEPATGDILQVYEAPADGSTLIFDSSG
ADSLFGGLGDDTISGDFGNDTIDGGAGDDSLSGGAEQDVFQFTDGFGTDTVDGGEAGDDLDTLDFSQMTTGIDVMFDGDE
QGDVSDTGSTDSVEFTNIERVDGTGQDDTIDAGASNADQTLIGNDGADSIVGGSGNDTLYGDGGTSTPANGTLIYADNFD
GGNDGGWGSTPTDNTDPFFGSVLGRVQGTASSTDIEAQRTLTFDPAYDDAVIEFDFHRIDSWDNEDFQIYANGQEIFSQT
FNPGTIVGGANTVTIGGVTYTITLTSQGDAAQNGYWDGQPWTTDQSFRVRIEVENAPETLDLGFGSTINQAVTDESYAFD
NFAVVSTNDTSIDPTDFINTGNDDTIEGGAGNDEIYGEEGNDVLDGGADNDTLFGGDGDDSVQGGAGQDSLIGGQGNDTL
VGGDDADWIFGGSGDVIDGGEGGDDNDTLFLGDDGAIIVYDTVNPENGTVTFSDGTTLTFQNIETVIPCFTPGCRVATAR
GTSKVEDLRVGDLIETHDNGLQAVRWIGAKTLTQIDLARAPHLRPIRIRTGALGPGVPNRDMEVSPQHRMLIEGGQTELL
FGEDQVLVRAKHLTHLPGVEVVKTCERVTYIHVMCDAHEVIRVDDAWTESFQPGDLVQDHEAREIFGDLLHAFPGLGTEA
GRETYVSARLSLKAHEAGLVRI
>Mature_1461_residues
ATINGDGTDNTLTGTGAADDITGFAGNDTITGGNGNDAIDGGAPSLTPTALDLNWTAQGGNGTNLAGGFTQNTGGIDVAV
SFTNDGGGSAAQVSTSTTFVDTGETYDANSNLSMTGNGGSDVWTVDVDFSSVGGSGFADEVENVAFRLQDIDTGGWQDIV
TVNAYDADGNLIPVILTPSGGDTVSGNTVTAGPGATAASSSEGSVLVEIAGPVARFEIIYQNGGTSGQLGLVTDVQFDAV
PTDDDELFGEAGNDTITGGFGDDLLDGGTNNDVLDGGSGNDTLIGGSGNDTLDGGAGQDSLEGGTGADVLTGGDGNDTLG
GGGGADTLDGGDGDDSLSGGSGFDVLTGGEGADTLDGGNGNDIFNAGSGDVVIGGEGGTDTNDQLIVDDVAEVIFDPLNS
ENGTVVFNDGSTATFTGIETLVVNGGPDGVVDGTFGNDVIDSDYVDPNLEQVDNGDGTLGTAGDEDVIEAGFGDDTVYAG
EGNDSIEGGPSGPLNSATENFSWIAEGDGTDISGGITQDTGVANITVGITNDGALNQSAITNTTQYVDGADPFSATSGLA
LGGSGGADVATLDFAADAELTGVSFRLNDIDAGAWEDIVTVNAYDPNGNLVPVVLTPETAGDVVTGQTVTGAGTDNPNQI
GGSVLVEIAGPITRFEVIYENGSTGGQVVYLTDIHYTASETDDDVLHGDQGGDTIDGGAGNDVIFGDQMAVDPADIPSGT
GGTATSATFQNDSPYAVGLAQVDASGVVVPVITIPAGSDYTAPSTTQTNWVLLEPATGDILQVYEAPADGSTLIFDSSGA
DSLFGGLGDDTISGDFGNDTIDGGAGDDSLSGGAEQDVFQFTDGFGTDTVDGGEAGDDLDTLDFSQMTTGIDVMFDGDEQ
GDVSDTGSTDSVEFTNIERVDGTGQDDTIDAGASNADQTLIGNDGADSIVGGSGNDTLYGDGGTSTPANGTLIYADNFDG
GNDGGWGSTPTDNTDPFFGSVLGRVQGTASSTDIEAQRTLTFDPAYDDAVIEFDFHRIDSWDNEDFQIYANGQEIFSQTF
NPGTIVGGANTVTIGGVTYTITLTSQGDAAQNGYWDGQPWTTDQSFRVRIEVENAPETLDLGFGSTINQAVTDESYAFDN
FAVVSTNDTSIDPTDFINTGNDDTIEGGAGNDEIYGEEGNDVLDGGADNDTLFGGDGDDSVQGGAGQDSLIGGQGNDTLV
GGDDADWIFGGSGDVIDGGEGGDDNDTLFLGDDGAIIVYDTVNPENGTVTFSDGTTLTFQNIETVIPCFTPGCRVATARG
TSKVEDLRVGDLIETHDNGLQAVRWIGAKTLTQIDLARAPHLRPIRIRTGALGPGVPNRDMEVSPQHRMLIEGGQTELLF
GEDQVLVRAKHLTHLPGVEVVKTCERVTYIHVMCDAHEVIRVDDAWTESFQPGDLVQDHEAREIFGDLLHAFPGLGTEAG
RETYVSARLSLKAHEAGLVRI

Specific function: Does not have hemolytic activity but shows a strong cytotoxicity towards alveolar macrophages and neutrophils [H]

COG id: COG2931

COG function: function code Q; RTX toxins and related Ca2+-binding proteins

Gene ontology:

Cell location: Secreted. Host cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 6 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR013550
- InterPro:   IPR018504
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF00353 HemolysinCabind; PF02382 RTX; PF08339 RTX_C [H]

EC number: NA

Molecular weight: Translated: 148626; Mature: 148495

Theoretical pI: Translated: 3.28; Mature: 3.28

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATINGDGTDNTLTGTGAADDITGFAGNDTITGGNGNDAIDGGAPSLTPTALDLNWTAQG
CEEECCCCCCCEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEEEEEECC
GNGTNLAGGFTQNTGGIDVAVSFTNDGGGSAAQVSTSTTFVDTGETYDANSNLSMTGNGG
CCCCCCCCCEECCCCCEEEEEEEECCCCCCEEEEECCEEEEECCCCCCCCCCEEEECCCC
SDVWTVDVDFSSVGGSGFADEVENVAFRLQDIDTGGWQDIVTVNAYDADGNLIPVILTPS
CEEEEEEEEHHCCCCCCCHHHHHCEEEEEEECCCCCCEEEEEEEEECCCCCEEEEEEECC
GGDTVSGNTVTAGPGATAASSSEGSVLVEIAGPVARFEIIYQNGGTSGQLGLVTDVQFDA
CCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCEEEEEEEEECCCCCCCEEEEEEEEECC
VPTDDDELFGEAGNDTITGGFGDDLLDGGTNNDVLDGGSGNDTLIGGSGNDTLDGGAGQD
CCCCCHHHHCCCCCCEEECCCCCHHHCCCCCCCEECCCCCCCEEEECCCCCCCCCCCCCC
SLEGGTGADVLTGGDGNDTLGGGGGADTLDGGDGDDSLSGGSGFDVLTGGEGADTLDGGN
CCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCC
GNDIFNAGSGDVVIGGEGGTDTNDQLIVDDVAEVIFDPLNSENGTVVFNDGSTATFTGIE
CCCEEECCCCCEEECCCCCCCCCCCEEHHHHHHHHHCCCCCCCCEEEECCCCEEEEECEE
TLVVNGGPDGVVDGTFGNDVIDSDYVDPNLEQVDNGDGTLGTAGDEDVIEAGFGDDTVYA
EEEEECCCCCEEECCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHCCCCCCCEEEE
GEGNDSIEGGPSGPLNSATENFSWIAEGDGTDISGGITQDTGVANITVGITNDGALNQSA
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHH
ITNTTQYVDGADPFSATSGLALGGSGGADVATLDFAADAELTGVSFRLNDIDAGAWEDIV
HCCCHHCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCEEEEEEEEEECCCCCCCCCEE
TVNAYDPNGNLVPVVLTPETAGDVVTGQTVTGAGTDNPNQIGGSVLVEIAGPITRFEVIY
EEEEECCCCCEEEEEECCCCCCCEEECCEEECCCCCCCHHCCCEEEEEECCCCEEEEEEE
ENGSTGGQVVYLTDIHYTASETDDDVLHGDQGGDTIDGGAGNDVIFGDQMAVDPADIPSG
ECCCCCCEEEEEEEEEEECCCCCCCEEECCCCCCCCCCCCCCCEEECCCEECCCCCCCCC
TGGTATSATFQNDSPYAVGLAQVDASGVVVPVITIPAGSDYTAPSTTQTNWVLLEPATGD
CCCCCEEEEECCCCCEEEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCC
ILQVYEAPADGSTLIFDSSGADSLFGGLGDDTISGDFGNDTIDGGAGDDSLSGGAEQDVF
EEEEEECCCCCCEEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
QFTDGFGTDTVDGGEAGDDLDTLDFSQMTTGIDVMFDGDEQGDVSDTGSTDSVEFTNIER
HHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEE
VDGTGQDDTIDAGASNADQTLIGNDGADSIVGGSGNDTLYGDGGTSTPANGTLIYADNFD
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEECCC
GGNDGGWGSTPTDNTDPFFGSVLGRVQGTASSTDIEAQRTLTFDPAYDDAVIEFDFHRID
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCEEEEEEEEECC
SWDNEDFQIYANGQEIFSQTFNPGTIVGGANTVTIGGVTYTITLTSQGDAAQNGYWDGQP
CCCCCCEEEEECCHHHHHCCCCCCEEECCCCEEEECCEEEEEEEECCCCCCCCCCCCCCC
WTTDQSFRVRIEVENAPETLDLGFGSTINQAVTDESYAFDNFAVVSTNDTSIDPTDFINT
CCCCCCEEEEEEECCCCCEEECCCCCCHHHHHCCCCEECCCEEEEECCCCCCCHHHCCCC
GNDDTIEGGAGNDEIYGEEGNDVLDGGADNDTLFGGDGDDSVQGGAGQDSLIGGQGNDTL
CCCCEECCCCCCCCCCCCCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCEECCCCCCEE
VGGDDADWIFGGSGDVIDGGEGGDDNDTLFLGDDGAIIVYDTVNPENGTVTFSDGTTLTF
ECCCCCCEEECCCCCEECCCCCCCCCCEEEECCCCCEEEEECCCCCCCEEEECCCCEEEE
QNIETVIPCFTPGCRVATARGTSKVEDLRVGDLIETHDNGLQAVRWIGAKTLTQIDLARA
CCCCEEEECCCCCCEEEECCCCCCHHHEECCCEEECCCCCHHHHHHHCHHHHHEEHHHCC
PHLRPIRIRTGALGPGVPNRDMEVSPQHRMLIEGGQTELLFGEDQVLVRAKHLTHLPGVE
CCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCEEEEEEEHHCCCCCHH
VVKTCERVTYIHVMCDAHEVIRVDDAWTESFQPGDLVQDHEAREIFGDLLHAFPGLGTEA
HHHHHHHEEEEEEEECCCEEEEECCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
GRETYVSARLSLKAHEAGLVRI
CCEEEEEEEEEEEECCCCEEEC
>Mature Secondary Structure 
ATINGDGTDNTLTGTGAADDITGFAGNDTITGGNGNDAIDGGAPSLTPTALDLNWTAQG
EEECCCCCCCEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEEEEEECC
GNGTNLAGGFTQNTGGIDVAVSFTNDGGGSAAQVSTSTTFVDTGETYDANSNLSMTGNGG
CCCCCCCCCEECCCCCEEEEEEEECCCCCCEEEEECCEEEEECCCCCCCCCCEEEECCCC
SDVWTVDVDFSSVGGSGFADEVENVAFRLQDIDTGGWQDIVTVNAYDADGNLIPVILTPS
CEEEEEEEEHHCCCCCCCHHHHHCEEEEEEECCCCCCEEEEEEEEECCCCCEEEEEEECC
GGDTVSGNTVTAGPGATAASSSEGSVLVEIAGPVARFEIIYQNGGTSGQLGLVTDVQFDA
CCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCEEEEEEEEECCCCCCCEEEEEEEEECC
VPTDDDELFGEAGNDTITGGFGDDLLDGGTNNDVLDGGSGNDTLIGGSGNDTLDGGAGQD
CCCCCHHHHCCCCCCEEECCCCCHHHCCCCCCCEECCCCCCCEEEECCCCCCCCCCCCCC
SLEGGTGADVLTGGDGNDTLGGGGGADTLDGGDGDDSLSGGSGFDVLTGGEGADTLDGGN
CCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCC
GNDIFNAGSGDVVIGGEGGTDTNDQLIVDDVAEVIFDPLNSENGTVVFNDGSTATFTGIE
CCCEEECCCCCEEECCCCCCCCCCCEEHHHHHHHHHCCCCCCCCEEEECCCCEEEEECEE
TLVVNGGPDGVVDGTFGNDVIDSDYVDPNLEQVDNGDGTLGTAGDEDVIEAGFGDDTVYA
EEEEECCCCCEEECCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHCCCCCCCEEEE
GEGNDSIEGGPSGPLNSATENFSWIAEGDGTDISGGITQDTGVANITVGITNDGALNQSA
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHH
ITNTTQYVDGADPFSATSGLALGGSGGADVATLDFAADAELTGVSFRLNDIDAGAWEDIV
HCCCHHCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCEEEEEEEEEECCCCCCCCCEE
TVNAYDPNGNLVPVVLTPETAGDVVTGQTVTGAGTDNPNQIGGSVLVEIAGPITRFEVIY
EEEEECCCCCEEEEEECCCCCCCEEECCEEECCCCCCCHHCCCEEEEEECCCCEEEEEEE
ENGSTGGQVVYLTDIHYTASETDDDVLHGDQGGDTIDGGAGNDVIFGDQMAVDPADIPSG
ECCCCCCEEEEEEEEEEECCCCCCCEEECCCCCCCCCCCCCCCEEECCCEECCCCCCCCC
TGGTATSATFQNDSPYAVGLAQVDASGVVVPVITIPAGSDYTAPSTTQTNWVLLEPATGD
CCCCCEEEEECCCCCEEEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCC
ILQVYEAPADGSTLIFDSSGADSLFGGLGDDTISGDFGNDTIDGGAGDDSLSGGAEQDVF
EEEEEECCCCCCEEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
QFTDGFGTDTVDGGEAGDDLDTLDFSQMTTGIDVMFDGDEQGDVSDTGSTDSVEFTNIER
HHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEE
VDGTGQDDTIDAGASNADQTLIGNDGADSIVGGSGNDTLYGDGGTSTPANGTLIYADNFD
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEECCC
GGNDGGWGSTPTDNTDPFFGSVLGRVQGTASSTDIEAQRTLTFDPAYDDAVIEFDFHRID
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCEEEEEEEEECC
SWDNEDFQIYANGQEIFSQTFNPGTIVGGANTVTIGGVTYTITLTSQGDAAQNGYWDGQP
CCCCCCEEEEECCHHHHHCCCCCCEEECCCCEEEECCEEEEEEEECCCCCCCCCCCCCCC
WTTDQSFRVRIEVENAPETLDLGFGSTINQAVTDESYAFDNFAVVSTNDTSIDPTDFINT
CCCCCCEEEEEEECCCCCEEECCCCCCHHHHHCCCCEECCCEEEEECCCCCCCHHHCCCC
GNDDTIEGGAGNDEIYGEEGNDVLDGGADNDTLFGGDGDDSVQGGAGQDSLIGGQGNDTL
CCCCEECCCCCCCCCCCCCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCEECCCCCCEE
VGGDDADWIFGGSGDVIDGGEGGDDNDTLFLGDDGAIIVYDTVNPENGTVTFSDGTTLTF
ECCCCCCEEECCCCCEECCCCCCCCCCEEEECCCCCEEEEECCCCCCCEEEECCCCEEEE
QNIETVIPCFTPGCRVATARGTSKVEDLRVGDLIETHDNGLQAVRWIGAKTLTQIDLARA
CCCCEEEECCCCCCEEEECCCCCCHHHEECCCEEECCCCCHHHHHHHCHHHHHEEHHHCC
PHLRPIRIRTGALGPGVPNRDMEVSPQHRMLIEGGQTELLFGEDQVLVRAKHLTHLPGVE
CCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCEEEEEEEHHCCCCCHH
VVKTCERVTYIHVMCDAHEVIRVDDAWTESFQPGDLVQDHEAREIFGDLLHAFPGLGTEA
HHHHHHHEEEEEEEECCCEEEEECCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
GRETYVSARLSLKAHEAGLVRI
CCEEEEEEEEEEEECCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7927703; 8432615 [H]