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The map label for this gene is uhpB [H]

Identifier: 89056007

GI number: 89056007

Start: 3571943

End: 3573787

Strand: Direct

Name: uhpB [H]

Synonym: Jann_3516

Alternate gene names: 89056007

Gene position: 3571943-3573787 (Clockwise)

Preceding gene: 89056006

Following gene: 89056008

Centisome position: 82.72

GC content: 62.01

Gene sequence:

>1845_bases
GTGAACGGAAAGATCTTGCGGATTTCGGTGGCGATGGCGCTTTGGATCGCATCGCTGACCGCGCTTTTGTTTGCCCTGAA
TATCGGACGCGCCGTCCCTATTGACGGGGCCCGGCTTATCGAGACGGCCACACTTTGCTCCGATCCCGCGCGACCTGCGA
CCTGTGCGGATATCTCTTTGCCCTACCATTCCGAACGGCCAACTCAGGATCGCACCCTCACCCGGTATTTTGCCGTGGAC
ATCCCGTTGGACCCTGCGACGGAGGGCCTGCAGGCCCTCTACCTGCCCAAACTTGCAGATACGGTCACAGTGACGCTCAA
CGGCGAAACTCTGTTCGAGCCGCCCATGAACCGCAGCCTGGATAGTACGCCCGTGCTGATCCCCATTCCGCCTGCTCTGC
TAGACGACGATATGGCGCGGTTCGTCCTGACGCTTCGGGGGGCCGCGCCGGAAGGGTTGGACCTCTGGCCATTCCATATC
GGCCCCCACGCGCACCTCGCCCCGGTCCACGACACCCGCATGAGTTTTGGGCCGGGCGTGGCGCGGTTCTCCATGGGCAT
CATGGCCGTACTGGCGATTGCCCTGCTGTTGATCTGGTGGAACCGCCGGGCCGAACGGCACTATCTCTGGCTCGCGGCCT
CCTGTCTCAGCGTGCTCTTCATCCTGACGCACATCGCATTCGGCGCATCAATTGGATCCTACAAGATATGGACGATCCTG
TGGTCGTTCTCGGCGGCGGTCTACGTCTTCACCATCCTGAAGTTTCTACGTCACTTCCTGTCGCTGCCCGTTCTGACGTT
GGAAAGGGTACACCTCAGCTCGATCCTGCTATGTGCGCTCGTCGCGCTTGTCTTGCCGGGGGGGTACACCTTCTCGGTCT
CGCTCACCATCAATGCGCTCAGCGCCCCGTCCGCGCTGGCCGTCCTCGTGCTGCTGTGGATGCGCCGGACGGAGCTTGCA
GGGCGCGATTTTGCCGTGTTCTTCACCTGCATGTCTATTGCGGTGACATTGGGTGTCTACACCCTGACCATTACGGCCTT
GCCCAACACGCCGCGCAGCTTGCAACTGTATCAGATCATGCCGTTGGTCATGTCATTTGCCTGCGTCTATCTTATCCTGG
CGAAATTCCTGCAAAGCCTGCACGGATATGAGGCGTTGACCACGTCCTTGAACCAGACCCTCGACCAACGCACCCGGGAA
TTGGAAGAGAGTTTCACCCGCCTTGCCCAGACCGAAAAGCGAGAGGTGATTGCCCAGGAACGCTCTCGCATCATGCTGGA
TCTGCATGACGGGTTGGGCGGTCAGTTGGTGAATACGCTGGCCTATATTCGCCGCACGGGATCAGGGGATGACACGATCC
GCCTGGCCTTGGAGGATGCGTTGCGCGACCTTGCCATGATGCTGGACAGTGTCGAAAGCCAGGAAAGCCTGGTGACCCTT
CTGGGCATGATGCGCACGCGGCTGGAGGGTCTTTTGGCCGACAACGGGATCACATTCGACTGGCAAATCGGCGATGAGCC
CGTGGCGCCCGTGTCCGGCCCCTCCCCCAACCTGAACTTGGCGCGGATCGTGCAGGAGGCGATTACCAACGTGATCAAAC
ACGCCGACGCGAGCGTGATCCGCGTGGAAACGGACGCGCGCACCATCTCCATCAGCGACAACGGCACGGGGTTCGATGCG
GAAGCCGGGCGCGCGGGGTCGCAGGGCCACGGGATCTCCAACATGCGGCGCCGGGCGGAGGCATTGGGCGCCCGGCTGGA
GATCGCATCAGACGCGTCCGGCACGCGGGTGTCACTCGCGTTTCCTGACGCGGCTGCCCCCAAGCCCTGCTCCGATGCCG
CGTGA

Upstream 100 bases:

>100_bases
CGGCCGGCACCGTGGGCAATCACATCACCAGCATCTATCGCAAGCTGGAGGTGTCCTCCAACATCGAGGCGGTGGCCATC
GCCTCCCGGAGTGGCATGTT

Downstream 100 bases:

>100_bases
ATAGCACTGCGGATGCCCTGGTTATCGGTCATCGCCCGCTCACGGTGAGGATTGTGAAACCTGGCTATGGCAGGGGTAGA
CCGTTGTAATCATGGTGCCT

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 614; Mature: 614

Protein sequence:

>614_residues
MNGKILRISVAMALWIASLTALLFALNIGRAVPIDGARLIETATLCSDPARPATCADISLPYHSERPTQDRTLTRYFAVD
IPLDPATEGLQALYLPKLADTVTVTLNGETLFEPPMNRSLDSTPVLIPIPPALLDDDMARFVLTLRGAAPEGLDLWPFHI
GPHAHLAPVHDTRMSFGPGVARFSMGIMAVLAIALLLIWWNRRAERHYLWLAASCLSVLFILTHIAFGASIGSYKIWTIL
WSFSAAVYVFTILKFLRHFLSLPVLTLERVHLSSILLCALVALVLPGGYTFSVSLTINALSAPSALAVLVLLWMRRTELA
GRDFAVFFTCMSIAVTLGVYTLTITALPNTPRSLQLYQIMPLVMSFACVYLILAKFLQSLHGYEALTTSLNQTLDQRTRE
LEESFTRLAQTEKREVIAQERSRIMLDLHDGLGGQLVNTLAYIRRTGSGDDTIRLALEDALRDLAMMLDSVESQESLVTL
LGMMRTRLEGLLADNGITFDWQIGDEPVAPVSGPSPNLNLARIVQEAITNVIKHADASVIRVETDARTISISDNGTGFDA
EAGRAGSQGHGISNMRRRAEALGARLEIASDASGTRVSLAFPDAAAPKPCSDAA

Sequences:

>Translated_614_residues
MNGKILRISVAMALWIASLTALLFALNIGRAVPIDGARLIETATLCSDPARPATCADISLPYHSERPTQDRTLTRYFAVD
IPLDPATEGLQALYLPKLADTVTVTLNGETLFEPPMNRSLDSTPVLIPIPPALLDDDMARFVLTLRGAAPEGLDLWPFHI
GPHAHLAPVHDTRMSFGPGVARFSMGIMAVLAIALLLIWWNRRAERHYLWLAASCLSVLFILTHIAFGASIGSYKIWTIL
WSFSAAVYVFTILKFLRHFLSLPVLTLERVHLSSILLCALVALVLPGGYTFSVSLTINALSAPSALAVLVLLWMRRTELA
GRDFAVFFTCMSIAVTLGVYTLTITALPNTPRSLQLYQIMPLVMSFACVYLILAKFLQSLHGYEALTTSLNQTLDQRTRE
LEESFTRLAQTEKREVIAQERSRIMLDLHDGLGGQLVNTLAYIRRTGSGDDTIRLALEDALRDLAMMLDSVESQESLVTL
LGMMRTRLEGLLADNGITFDWQIGDEPVAPVSGPSPNLNLARIVQEAITNVIKHADASVIRVETDARTISISDNGTGFDA
EAGRAGSQGHGISNMRRRAEALGARLEIASDASGTRVSLAFPDAAAPKPCSDAA
>Mature_614_residues
MNGKILRISVAMALWIASLTALLFALNIGRAVPIDGARLIETATLCSDPARPATCADISLPYHSERPTQDRTLTRYFAVD
IPLDPATEGLQALYLPKLADTVTVTLNGETLFEPPMNRSLDSTPVLIPIPPALLDDDMARFVLTLRGAAPEGLDLWPFHI
GPHAHLAPVHDTRMSFGPGVARFSMGIMAVLAIALLLIWWNRRAERHYLWLAASCLSVLFILTHIAFGASIGSYKIWTIL
WSFSAAVYVFTILKFLRHFLSLPVLTLERVHLSSILLCALVALVLPGGYTFSVSLTINALSAPSALAVLVLLWMRRTELA
GRDFAVFFTCMSIAVTLGVYTLTITALPNTPRSLQLYQIMPLVMSFACVYLILAKFLQSLHGYEALTTSLNQTLDQRTRE
LEESFTRLAQTEKREVIAQERSRIMLDLHDGLGGQLVNTLAYIRRTGSGDDTIRLALEDALRDLAMMLDSVESQESLVTL
LGMMRTRLEGLLADNGITFDWQIGDEPVAPVSGPSPNLNLARIVQEAITNVIKHADASVIRVETDARTISISDNGTGFDA
EAGRAGSQGHGISNMRRRAEALGARLEIASDASGTRVSLAFPDAAAPKPCSDAA

Specific function: Member of the two-component regulatory system uhpB/uhpA involved in the regulation of the uptake of hexose phosphates. UhpB functions as a membrane-associated protein kinase that phosphorylates uhpA in response to environmental signals [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=222, Percent_Identity=29.2792792792793, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR007895
- InterPro:   IPR011712
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3; PF05231 MASE1 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66957; Mature: 66957

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGKILRISVAMALWIASLTALLFALNIGRAVPIDGARLIETATLCSDPARPATCADISL
CCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEC
PYHSERPTQDRTLTRYFAVDIPLDPATEGLQALYLPKLADTVTVTLNGETLFEPPMNRSL
CCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEECCCEEECCCCCCCC
DSTPVLIPIPPALLDDDMARFVLTLRGAAPEGLDLWPFHIGPHAHLAPVHDTRMSFGPGV
CCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCEECEEEECCCCCCCCCCCCCCCCCCCH
ARFSMGIMAVLAIALLLIWWNRRAERHYLWLAASCLSVLFILTHIAFGASIGSYKIWTIL
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHH
WSFSAAVYVFTILKFLRHFLSLPVLTLERVHLSSILLCALVALVLPGGYTFSVSLTINAL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEC
SAPSALAVLVLLWMRRTELAGRDFAVFFTCMSIAVTLGVYTLTITALPNTPRSLQLYQIM
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCHHHHHH
PLVMSFACVYLILAKFLQSLHGYEALTTSLNQTLDQRTRELEESFTRLAQTEKREVIAQE
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSRIMLDLHDGLGGQLVNTLAYIRRTGSGDDTIRLALEDALRDLAMMLDSVESQESLVTL
HCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCHHHHHHHH
LGMMRTRLEGLLADNGITFDWQIGDEPVAPVSGPSPNLNLARIVQEAITNVIKHADASVI
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEE
RVETDARTISISDNGTGFDAEAGRAGSQGHGISNMRRRAEALGARLEIASDASGTRVSLA
EEEECCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEEE
FPDAAAPKPCSDAA
CCCCCCCCCCCCCC
>Mature Secondary Structure
MNGKILRISVAMALWIASLTALLFALNIGRAVPIDGARLIETATLCSDPARPATCADISL
CCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEC
PYHSERPTQDRTLTRYFAVDIPLDPATEGLQALYLPKLADTVTVTLNGETLFEPPMNRSL
CCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEECCCEEECCCCCCCC
DSTPVLIPIPPALLDDDMARFVLTLRGAAPEGLDLWPFHIGPHAHLAPVHDTRMSFGPGV
CCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCEECEEEECCCCCCCCCCCCCCCCCCCH
ARFSMGIMAVLAIALLLIWWNRRAERHYLWLAASCLSVLFILTHIAFGASIGSYKIWTIL
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHH
WSFSAAVYVFTILKFLRHFLSLPVLTLERVHLSSILLCALVALVLPGGYTFSVSLTINAL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEC
SAPSALAVLVLLWMRRTELAGRDFAVFFTCMSIAVTLGVYTLTITALPNTPRSLQLYQIM
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCHHHHHH
PLVMSFACVYLILAKFLQSLHGYEALTTSLNQTLDQRTRELEESFTRLAQTEKREVIAQE
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSRIMLDLHDGLGGQLVNTLAYIRRTGSGDDTIRLALEDALRDLAMMLDSVESQESLVTL
HCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCHHHHHHHH
LGMMRTRLEGLLADNGITFDWQIGDEPVAPVSGPSPNLNLARIVQEAITNVIKHADASVI
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEE
RVETDARTISISDNGTGFDAEAGRAGSQGHGISNMRRRAEALGARLEIASDASGTRVSLA
EEEECCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEEE
FPDAAAPKPCSDAA
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3301805; 1569007; 7686882; 9278503 [H]