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The map label for this gene is trxB [H]

Identifier: 89055829

GI number: 89055829

Start: 3389265

End: 3390260

Strand: Direct

Name: trxB [H]

Synonym: Jann_3338

Alternate gene names: 89055829

Gene position: 3389265-3390260 (Clockwise)

Preceding gene: 89055826

Following gene: 89055831

Centisome position: 78.49

GC content: 64.66

Gene sequence:

>996_bases
ATGTCCAACCCCCGCCACACCCGCCTTCTTATCATCGGCTCCGGCCCTGCCGGCTACACCGCCGGGGTCTATGCCAGCCG
CGCGATGCTGGAGCCCATTCTGGTTCAAGGCATTCAGCCCGGCGGCCAGCTGACGATCACCACGGATGTGGAGAACTGGC
CCGGCGACGCGTCCGTCATGGGCCCTGATCTGATGGTGCGGATGGAGGCCCACGCCAAGGAGATGGGGACCGAGATCATT
GGCGATCATATCTCCTCACTGGATCTGTCCAAGCGTCCCTTCACGGCGCAGGGCGACAGCGGCACGACCTATACGGCGGA
CGCGGTTGTGCTGGCCACGGGCGCGCAAGCCAAGTGGTTGGGGCTGCCCAGTGAGGAGCATTTCAAAGGCTTCGGCGTCT
CAGCCTGCGCCACCTGCGACGGCTTCTTCTATCGCGGGATGGAGATTGTGGTGATCGGCGGCGGCAACACGGCCGTGGAA
GAGGCGCTGTTTCTGACGAACTTCGCCAGCAAGGTCACCCTGATCCACCGCCGCGACAGCCTGCGGGCGGAAAAGATCAT
GCAGGACCGCCTGTTCAAGAACCCCAAGGTGGAGGTTTTGTGGGACCATTCGGTGGAGGAGGTCGTGGGCACCTCCGAGC
CGCGCGGCGTGGAGGGCGTGCGTGCGCGTCACGTGAAGACCGGGGAAATCACGGAAATCCCCTGCAAGGGCTTCTTCGTC
GCCATCGGCCACGCGCCTGCGACGGAATTGGTCAAGGACCAGTTGGAGATGCATAACGGCGGCTATGTGAAAGTGCAGGC
GGGTACGACGAAAACGTCGATCCCGGGTGTGTTTGCGGCGGGCGATCTGACCGACCACGTCTACCGCCAGGCGGTGACGA
GCGCCGGAATGGGCTGCATGGCGGCGCTGGATGCCGAGAAATTCCTGGCCGAGATGGACGGCGAGGAGACGGTGGAGGCC
GGGGCATACGCCGCGCCTGTGACCGCGGCGGAATGA

Upstream 100 bases:

>100_bases
AGGACACTTGACCGTGAAACGAATTCTCTTGGGGTTTCATCGGGAGAGCGGCGGGGATATATCGGCAAGACCTTTTCCCC
TGCTGCCACAGGATGCGCCT

Downstream 100 bases:

>100_bases
GGGGCGGTGCATCACCGACGGCGGTCACGGACAGTGCGTTTGTGCCAGTCATCCAGGCGCTGAAACCGATCGGTGCCGAC
CAACCGTTTTAGGGTTGATT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSNPRHTRLLIIGSGPAGYTAGVYASRAMLEPILVQGIQPGGQLTITTDVENWPGDASVMGPDLMVRMEAHAKEMGTEII
GDHISSLDLSKRPFTAQGDSGTTYTADAVVLATGAQAKWLGLPSEEHFKGFGVSACATCDGFFYRGMEIVVIGGGNTAVE
EALFLTNFASKVTLIHRRDSLRAEKIMQDRLFKNPKVEVLWDHSVEEVVGTSEPRGVEGVRARHVKTGEITEIPCKGFFV
AIGHAPATELVKDQLEMHNGGYVKVQAGTTKTSIPGVFAAGDLTDHVYRQAVTSAGMGCMAALDAEKFLAEMDGEETVEA
GAYAAPVTAAE

Sequences:

>Translated_331_residues
MSNPRHTRLLIIGSGPAGYTAGVYASRAMLEPILVQGIQPGGQLTITTDVENWPGDASVMGPDLMVRMEAHAKEMGTEII
GDHISSLDLSKRPFTAQGDSGTTYTADAVVLATGAQAKWLGLPSEEHFKGFGVSACATCDGFFYRGMEIVVIGGGNTAVE
EALFLTNFASKVTLIHRRDSLRAEKIMQDRLFKNPKVEVLWDHSVEEVVGTSEPRGVEGVRARHVKTGEITEIPCKGFFV
AIGHAPATELVKDQLEMHNGGYVKVQAGTTKTSIPGVFAAGDLTDHVYRQAVTSAGMGCMAALDAEKFLAEMDGEETVEA
GAYAAPVTAAE
>Mature_330_residues
SNPRHTRLLIIGSGPAGYTAGVYASRAMLEPILVQGIQPGGQLTITTDVENWPGDASVMGPDLMVRMEAHAKEMGTEIIG
DHISSLDLSKRPFTAQGDSGTTYTADAVVLATGAQAKWLGLPSEEHFKGFGVSACATCDGFFYRGMEIVVIGGGNTAVEE
ALFLTNFASKVTLIHRRDSLRAEKIMQDRLFKNPKVEVLWDHSVEEVVGTSEPRGVEGVRARHVKTGEITEIPCKGFFVA
IGHAPATELVKDQLEMHNGGYVKVQAGTTKTSIPGVFAAGDLTDHVYRQAVTSAGMGCMAALDAEKFLAEMDGEETVEAG
AYAAPVTAAE

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=318, Percent_Identity=58.8050314465409, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI87081763, Length=308, Percent_Identity=31.8181818181818, Blast_Score=138, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6320560, Length=319, Percent_Identity=46.7084639498433, Blast_Score=285, Evalue=7e-78,
Organism=Saccharomyces cerevisiae, GI6321898, Length=321, Percent_Identity=45.7943925233645, Blast_Score=274, Evalue=2e-74,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 35229; Mature: 35098

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPRHTRLLIIGSGPAGYTAGVYASRAMLEPILVQGIQPGGQLTITTDVENWPGDASVM
CCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEE
GPDLMVRMEAHAKEMGTEIIGDHISSLDLSKRPFTAQGDSGTTYTADAVVLATGAQAKWL
CCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCEEEEEECCCEEEE
GLPSEEHFKGFGVSACATCDGFFYRGMEIVVIGGGNTAVEEALFLTNFASKVTLIHRRDS
CCCCHHHHCCCCCHHHHHHCCHHHCCEEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCH
LRAEKIMQDRLFKNPKVEVLWDHSVEEVVGTSEPRGVEGVRARHVKTGEITEIPCKGFFV
HHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCCCCHHHEEEECCCEEECCCCCEEE
AIGHAPATELVKDQLEMHNGGYVKVQAGTTKTSIPGVFAAGDLTDHVYRQAVTSAGMGCM
EECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCHH
AALDAEKFLAEMDGEETVEAGAYAAPVTAAE
HHHHHHHHHHHCCCCHHHHCCCEECCCCCCC
>Mature Secondary Structure 
SNPRHTRLLIIGSGPAGYTAGVYASRAMLEPILVQGIQPGGQLTITTDVENWPGDASVM
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEE
GPDLMVRMEAHAKEMGTEIIGDHISSLDLSKRPFTAQGDSGTTYTADAVVLATGAQAKWL
CCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCEEEEEECCCEEEE
GLPSEEHFKGFGVSACATCDGFFYRGMEIVVIGGGNTAVEEALFLTNFASKVTLIHRRDS
CCCCHHHHCCCCCHHHHHHCCHHHCCEEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCH
LRAEKIMQDRLFKNPKVEVLWDHSVEEVVGTSEPRGVEGVRARHVKTGEITEIPCKGFFV
HHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCCCCHHHEEEECCCEEECCCCCEEE
AIGHAPATELVKDQLEMHNGGYVKVQAGTTKTSIPGVFAAGDLTDHVYRQAVTSAGMGCM
EECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCHH
AALDAEKFLAEMDGEETVEAGAYAAPVTAAE
HHHHHHHHHHHCCCCHHHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]