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The map label for this gene is appC [H]

Identifier: 89055789

GI number: 89055789

Start: 3351933

End: 3352982

Strand: Direct

Name: appC [H]

Synonym: Jann_3298

Alternate gene names: 89055789

Gene position: 3351933-3352982 (Clockwise)

Preceding gene: 89055788

Following gene: 89055793

Centisome position: 77.63

GC content: 63.43

Gene sequence:

>1050_bases
ATGACTGAGACCTCATCCGATATCCAAATCTCCCACGCGCCGCGCAACCAGTGGTGGGATGTCTGGGACCAGTTCCGCAC
CCACAAGGGCGCGCTCTTCGGGTTGGCATTCTTCGTCTTCTCGCTGATGTTCGTCTATCTGGGGCCGCTGTTCTGGACAC
TCGACAGTCAGTATATCGACATCCGGGCGCGCAACACGAACCACATCCTCGCCTGCCTGGGCGTGGGCGGCGGCTGGTTC
TCCCCCGAAGGATGGGCGGCGTGGTTCCGCGATATGCCCGCCTGTTTCGCCTCACCCGAGGAGTTCGGTCGCGCCAATCC
GATCTATGCGCTGAAGGTGTCCTGGGCACACCCCCTTGGCGCGGACCAACTGGGCCGCGATACGCTGTCGCGCATGATGG
TCGGGGGGCAAACCTCCATCGCCGTCGGCCTGACCGCGATGCTTCTGGCGCTGTTTTTCGGCACGCTGATCGGCGTCGTG
GCGGGCTATTTCAAACGGGTCGACGGGTTGCTGATGCGCTTCACGGATCTGTTTCTCGCCATGCCCCTTCTGCCGCTGCT
GCTGGTGATCATCATGCTGTTCCGTGACACTCTGCGGAACGCGTTTGGCCCCGAGGGCGGGATCTTCGTGCTGATCGTGG
TGGTCATTGGCCTGACGTCCTGGATGCAGACCGCGCGCGTGGTGCGCGGCGATGTGCTGGCCCTGAAAGAGCGGGAGTTC
GTTCTGGCCGCACGCTCCATTGGCACACCACCCTGGCGGTTGATCCTGCGCCATGTGCTGCCCAACGTGATGTCGTCGAT
CATGGTGTCCGCCACGCTCGGGATCGCCAACGCGATCATCACCGAGTCCGCCCTGTCCTTTCTGGGCCTGGGCTTCCCGT
CGGACTTCCCCACCTGGGGCCGGTTGCTGTTTGATGCCACCGATTGGCTGAGCCAGAACCCCGAGCGGGTGATCTGGCCG
GGCCTGTTCATCTCGCTGACGGTGCTGTCGGTCAACTATATTGGCGACGGATTGCGCGATGCCCTCGATCCGCGGATACG
CGGACGGTAG

Upstream 100 bases:

>100_bases
TCAGCTTCATCTTCGCGATCCTGATCGTGCTCTTCAACCTGCTCGCCGATATTCTCTACGGCGTGCTGGACCCCCGCATT
CGTTATGATTGAGATCCGCC

Downstream 100 bases:

>100_bases
TTAGGTGTTCTGCGGATACGCGGACGGTAATTGGGTGATCCGCGGATACGTGGACGGTCAGCCGGGCTAAGAAACGGCCA
GGGCGCGGGCATAGATCCGC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MTETSSDIQISHAPRNQWWDVWDQFRTHKGALFGLAFFVFSLMFVYLGPLFWTLDSQYIDIRARNTNHILACLGVGGGWF
SPEGWAAWFRDMPACFASPEEFGRANPIYALKVSWAHPLGADQLGRDTLSRMMVGGQTSIAVGLTAMLLALFFGTLIGVV
AGYFKRVDGLLMRFTDLFLAMPLLPLLLVIIMLFRDTLRNAFGPEGGIFVLIVVVIGLTSWMQTARVVRGDVLALKEREF
VLAARSIGTPPWRLILRHVLPNVMSSIMVSATLGIANAIITESALSFLGLGFPSDFPTWGRLLFDATDWLSQNPERVIWP
GLFISLTVLSVNYIGDGLRDALDPRIRGR

Sequences:

>Translated_349_residues
MTETSSDIQISHAPRNQWWDVWDQFRTHKGALFGLAFFVFSLMFVYLGPLFWTLDSQYIDIRARNTNHILACLGVGGGWF
SPEGWAAWFRDMPACFASPEEFGRANPIYALKVSWAHPLGADQLGRDTLSRMMVGGQTSIAVGLTAMLLALFFGTLIGVV
AGYFKRVDGLLMRFTDLFLAMPLLPLLLVIIMLFRDTLRNAFGPEGGIFVLIVVVIGLTSWMQTARVVRGDVLALKEREF
VLAARSIGTPPWRLILRHVLPNVMSSIMVSATLGIANAIITESALSFLGLGFPSDFPTWGRLLFDATDWLSQNPERVIWP
GLFISLTVLSVNYIGDGLRDALDPRIRGR
>Mature_348_residues
TETSSDIQISHAPRNQWWDVWDQFRTHKGALFGLAFFVFSLMFVYLGPLFWTLDSQYIDIRARNTNHILACLGVGGGWFS
PEGWAAWFRDMPACFASPEEFGRANPIYALKVSWAHPLGADQLGRDTLSRMMVGGQTSIAVGLTAMLLALFFGTLIGVVA
GYFKRVDGLLMRFTDLFLAMPLLPLLLVIIMLFRDTLRNAFGPEGGIFVLIVVVIGLTSWMQTARVVRGDVLALKEREFV
LAARSIGTPPWRLILRHVLPNVMSSIMVSATLGIANAIITESALSFLGLGFPSDFPTWGRLLFDATDWLSQNPERVIWPG
LFISLTVLSVNYIGDGLRDALDPRIRGR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=236, Percent_Identity=39.8305084745763, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1787498, Length=232, Percent_Identity=38.3620689655172, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789964, Length=278, Percent_Identity=37.410071942446, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789889, Length=257, Percent_Identity=33.4630350194552, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787760, Length=237, Percent_Identity=32.9113924050633, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788505, Length=270, Percent_Identity=29.2592592592593, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787549, Length=274, Percent_Identity=29.1970802919708, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 38845; Mature: 38714

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETSSDIQISHAPRNQWWDVWDQFRTHKGALFGLAFFVFSLMFVYLGPLFWTLDSQYID
CCCCCCCEEEEECCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
IRARNTNHILACLGVGGGWFSPEGWAAWFRDMPACFASPEEFGRANPIYALKVSWAHPLG
EEECCCCEEEEEEECCCCCCCCCHHHHHHHHCCHHHCCHHHHCCCCCEEEEEEECCCCCC
ADQLGRDTLSRMMVGGQTSIAVGLTAMLLALFFGTLIGVVAGYFKRVDGLLMRFTDLFLA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MPLLPLLLVIIMLFRDTLRNAFGPEGGIFVLIVVVIGLTSWMQTARVVRGDVLALKEREF
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAARSIGTPPWRLILRHVLPNVMSSIMVSATLGIANAIITESALSFLGLGFPSDFPTWG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
RLLFDATDWLSQNPERVIWPGLFISLTVLSVNYIGDGLRDALDPRIRGR
HHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHCCHHHHHCCCCCCCC
>Mature Secondary Structure 
TETSSDIQISHAPRNQWWDVWDQFRTHKGALFGLAFFVFSLMFVYLGPLFWTLDSQYID
CCCCCCEEEEECCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
IRARNTNHILACLGVGGGWFSPEGWAAWFRDMPACFASPEEFGRANPIYALKVSWAHPLG
EEECCCCEEEEEEECCCCCCCCCHHHHHHHHCCHHHCCHHHHCCCCCEEEEEEECCCCCC
ADQLGRDTLSRMMVGGQTSIAVGLTAMLLALFFGTLIGVVAGYFKRVDGLLMRFTDLFLA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MPLLPLLLVIIMLFRDTLRNAFGPEGGIFVLIVVVIGLTSWMQTARVVRGDVLALKEREF
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAARSIGTPPWRLILRHVLPNVMSSIMVSATLGIANAIITESALSFLGLGFPSDFPTWG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
RLLFDATDWLSQNPERVIWPGLFISLTVLSVNYIGDGLRDALDPRIRGR
HHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]