BacMap

Definition	Jannaschia sp. CCS1 chromosome, complete genome.
Accession	NC_007802
Length	4,317,977

Click here to switch to the map view.

The map label for this gene is hbdH1 [H]

Identifier: 89055774

GI number: 89055774

Start: 3335317

End: 3336078

Strand: Direct

Name: hbdH1 [H]

Synonym: Jann_3283

Alternate gene names: 89055774

Gene position: 3335317-3336078 (Clockwise)

Preceding gene: 89055766

Following gene: 89055775

Centisome position: 77.24

GC content: 65.75

Gene sequence:

>762_bases
ATGGAGCATAAGGATCGTCATGCCATCGTGACAGGCGGCGGCACGGGCATCGGGTTGGGGATCGCGCTGGCGCTGGCGGG
TGCGGGCGCGCAGGTGACAATCACCGGGCGTGATGAACGGCGGCTGGCCTCGGTGGCCGCGATGCACCCCCGCCTGCACG
CCCTTGGAATGGATGTCTCGTCCGAGGCATCCGTGCGCGATGGCGTCGATCAGGCCGCAGACGCGCGGGGCCCGGTCTCC
ATTTGCATCGCCAATGCCGGTATCGCCGAACCCGCCTCGTTCCGGTCCGAGACGCTGGCCCATTGGCGCGAAACCATGAC
CACAAACCTCGATGGCGTGTTTTTGACGTTTCAGGCCGCGCTCAGCACGTTGGGGCGCGAAGAATGGGGGCGGATGATCG
CCATTTCCTCCATCGCGGGCCTGCGGGGCTTGAAGGGCGCGTCTGCCTACACGGCCTCCAAACACGGGGTGATCGGGCTG
GTGCGCGCCTTGTCCGAAGAACATCTGGGCGCAGAGATCACCTTTAACGCCATCTGTCCCGGCTATGTCGACACGCCCAT
CGTGGACCGCAATGCCGAACAAATCGCCAAATCCCAGAAGATGAGCGCCGAGGACGCCCGCGATCTGCTGGCCCGCGGTA
ACCGTCACAAGCGCCTGCTCGGCACCGATGAGGTGACCGCCACCGCCCTGTGGCTGTGTTCGTCCGCCGCGCGCAGTGTG
AACGGGCAATCGATCCAGATCGCGGGCGGTCAGGTCTCGTGA

Upstream 100 bases:

>100_bases
GGTAACACGACGGCCCGGCGTACATTTCTTGCGTATTCTCTGGTATACAGCGCCATATCATTGCGTCAGGCTTGTCGCAC
TCAATCAGAGGGTGAACAGA

Downstream 100 bases:

>100_bases
GGCCTGAATTATCGGGCCAATTGAGGCGCTTGCGGCGTTCGGTATACAATTGCACCCCGCCAACCCTCTAAAAACATTGG
TTTTTTTGGGTTTACACGCG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MEHKDRHAIVTGGGTGIGLGIALALAGAGAQVTITGRDERRLASVAAMHPRLHALGMDVSSEASVRDGVDQAADARGPVS
ICIANAGIAEPASFRSETLAHWRETMTTNLDGVFLTFQAALSTLGREEWGRMIAISSIAGLRGLKGASAYTASKHGVIGL
VRALSEEHLGAEITFNAICPGYVDTPIVDRNAEQIAKSQKMSAEDARDLLARGNRHKRLLGTDEVTATALWLCSSAARSV
NGQSIQIAGGQVS

Sequences:

>Translated_253_residues
MEHKDRHAIVTGGGTGIGLGIALALAGAGAQVTITGRDERRLASVAAMHPRLHALGMDVSSEASVRDGVDQAADARGPVS
ICIANAGIAEPASFRSETLAHWRETMTTNLDGVFLTFQAALSTLGREEWGRMIAISSIAGLRGLKGASAYTASKHGVIGL
VRALSEEHLGAEITFNAICPGYVDTPIVDRNAEQIAKSQKMSAEDARDLLARGNRHKRLLGTDEVTATALWLCSSAARSV
NGQSIQIAGGQVS
>Mature_253_residues
MEHKDRHAIVTGGGTGIGLGIALALAGAGAQVTITGRDERRLASVAAMHPRLHALGMDVSSEASVRDGVDQAADARGPVS
ICIANAGIAEPASFRSETLAHWRETMTTNLDGVFLTFQAALSTLGREEWGRMIAISSIAGLRGLKGASAYTASKHGVIGL
VRALSEEHLGAEITFNAICPGYVDTPIVDRNAEQIAKSQKMSAEDARDLLARGNRHKRLLGTDEVTATALWLCSSAARSV
NGQSIQIAGGQVS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4503817, Length=190, Percent_Identity=31.0526315789474, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI31542939, Length=205, Percent_Identity=30.7317073170732, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI40254992, Length=196, Percent_Identity=30.1020408163265, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI15277342, Length=265, Percent_Identity=30.5660377358491, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI66933014, Length=229, Percent_Identity=24.4541484716157, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI19923817, Length=261, Percent_Identity=27.9693486590038, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4504505, Length=257, Percent_Identity=28.0155642023346, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=25.968992248062, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI40807363, Length=188, Percent_Identity=28.7234042553192, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI20149619, Length=249, Percent_Identity=25.3012048192771, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI210032110, Length=185, Percent_Identity=26.4864864864865, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI109715829, Length=223, Percent_Identity=27.3542600896861, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI5031737, Length=256, Percent_Identity=26.953125, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=29.718875502008, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=30.6772908366534, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=27.8884462151394, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=30.5555555555556, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=27.0916334661355, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=27.7992277992278, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=27.1317829457364, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787526, Length=186, Percent_Identity=27.9569892473118, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=27.0916334661355, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=29.2, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=27.4509803921569, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17538182, Length=200, Percent_Identity=31.5, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=185, Percent_Identity=32.4324324324324, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=29.4820717131474, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=189, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17570069, Length=184, Percent_Identity=29.8913043478261, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=28.1746031746032, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=188, Percent_Identity=26.5957446808511, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=188, Percent_Identity=26.5957446808511, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=25.6916996047431, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=188, Percent_Identity=29.2553191489362, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=30.8900523560209, Blast_Score=79, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24641232, Length=217, Percent_Identity=29.0322580645161, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=27.843137254902, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=30.078125, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=29.2181069958848, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24665243, Length=225, Percent_Identity=27.1111111111111, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221331218, Length=225, Percent_Identity=27.1111111111111, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=26.953125, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=28.6852589641434, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI18859837, Length=191, Percent_Identity=31.9371727748691, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221331216, Length=226, Percent_Identity=26.9911504424779, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24665247, Length=226, Percent_Identity=26.9911504424779, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=27.2373540856031, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007234, Length=199, Percent_Identity=30.6532663316583, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356301, Length=193, Percent_Identity=26.9430051813472, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=26.6129032258064, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007236, Length=214, Percent_Identity=28.9719626168224, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571387, Length=199, Percent_Identity=30.1507537688442, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21355631, Length=175, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648944, Length=216, Percent_Identity=26.3888888888889, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007232, Length=176, Percent_Identity=30.1136363636364, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI281364892, Length=165, Percent_Identity=29.0909090909091, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24641388, Length=223, Percent_Identity=28.6995515695067, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 26435; Mature: 26435

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHKDRHAIVTGGGTGIGLGIALALAGAGAQVTITGRDERRLASVAAMHPRLHALGMDVS
CCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCHHHHHCCCCC
SEASVRDGVDQAADARGPVSICIANAGIAEPASFRSETLAHWRETMTTNLDGVFLTFQAA
CCCHHHHCHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHEEHHHHH
LSTLGREEWGRMIAISSIAGLRGLKGASAYTASKHGVIGLVRALSEEHLGAEITFNAICP
HHHHCHHHHCCEEEEHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCC
GYVDTPIVDRNAEQIAKSQKMSAEDARDLLARGNRHKRLLGTDEVTATALWLCSSAARSV
CCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHCC
NGQSIQIAGGQVS
CCCEEEECCCCCC
>Mature Secondary Structure
MEHKDRHAIVTGGGTGIGLGIALALAGAGAQVTITGRDERRLASVAAMHPRLHALGMDVS
CCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCHHHHHCCCCC
SEASVRDGVDQAADARGPVSICIANAGIAEPASFRSETLAHWRETMTTNLDGVFLTFQAA
CCCHHHHCHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHEEHHHHH
LSTLGREEWGRMIAISSIAGLRGLKGASAYTASKHGVIGLVRALSEEHLGAEITFNAICP
HHHHCHHHHCCEEEEHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCC
GYVDTPIVDRNAEQIAKSQKMSAEDARDLLARGNRHKRLLGTDEVTATALWLCSSAARSV
CCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHCC
NGQSIQIAGGQVS
CCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA