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The map label for this gene is ade2

Identifier: 89055724

GI number: 89055724

Start: 3280137

End: 3282008

Strand: Direct

Name: ade2

Synonym: Jann_3233

Alternate gene names: 89055724

Gene position: 3280137-3282008 (Clockwise)

Preceding gene: 89055723

Following gene: 89055725

Centisome position: 75.96

GC content: 64.64

Gene sequence:

>1872_bases
ATGACCGACCAACCCGCCCCGACAGACCACCTGATCCGAGCCGCCGATGAGGTGAAGATCCGCCAGCGGCTGGTGCGCGT
GGCGCTTGGCCATGTGGCAGGTGATACGCGGTTGCGGGTGGGCAAGCTGCTGGACGTCCATTCGCGGATGTGGCTGTCGG
ATCAGGAGATCATCCTGTCAGGCCGTCGCATCGCCTATGTCGGCCCGGCGGGGTCCTATCCGGGCGGTGTCGCGCATGAA
GTTCATGAGCCTGACCTGATGGCCGTGCCCGGCTTTGGCGAAGTGCACAAGCACATCGAAAGCTCTCACGTCACGCCGGA
GTGGGAGGCCGCGCTGGTCCTGCCCCACGGCAATACCTGGACCTGCGAGGCCAGCCACGAGTTCTCCAACGTCAACGGTC
CGCACAACCTGGAATTCTGGCTGACCGCACGGCTGGCTGGCAGCCCGCAGAAGATCTTCCCCCTGCCCGGCTCTGCCGTG
CCGCCCACAGCATACGAATGGGGCGGTGGGCATTTCGGCTATGACGAGCAGGCGGGATTTCTAAACGAAAGTCTGATGGT
CGCGGGCCTGGACGAGGTGATGGACTGGCCCGCCGTCTGGAACCCCGAGAACCCGTCCTATGACCGGCTCTGGGGCATGA
TCGAGGCGACGTTCGAGAAACGCGGCGTGATCGAGGGTCATGCGGCAGGCATTCGCGATATGGCCACGATCAACGCCTTT
GCCGCCGCCGGTCTGGCCTCCGATCACGAGGCATGGACCACGGAGGAGGTGCTCGACAAGCTCCGGCGCGGGTTGTTCAT
GGAGCTGCGCCCCCATTCCCTGTCCGAAATGGTCAAAGGCCTGCTGGAAGCGGGTTTGGAGGATTGGGGCCAGTTCGCCC
TGACCACCGATGACCGGTCCTGCTCGGACACTTTGAAGATGGGCGCGACGGACCACAACGTCCGCTTGGCCATATCGGCA
GGCCTAAGCCCCGAGGTCGCGATCCAGATGGTGACGATCAACCCCGCGCGGCATATGCGCCTGACGCCTTGGGTCGGGTC
CCTCGCGCCGGGCCGCTTCGCCGATATCGTGCTGCTGGACGACCTGCCGTCCGTATCGATCCGCCAAGTTTGGGCCGATG
GGGAGTTGGTCGCAGAGGATGGCACTTACCTGAAGCCCATCCCCAAGATCGACTGGCCGGACTGGGCAACACAAACGGTC
AAGATTGACCGCGCGATGATGGCCGATGACTTCGCGATCCCCGCCAAGCGCGGGCGCGACACGATGCATGCGGCGCTGCT
GCGCCCATTCCATTGGGATGACGACTTCATCACCATGGATCTGCCCGTGAAAGACGGCCAAGTGCAGCGCGACCCGCGCC
GCAACGTTACCAAATTTGCCATCGTCGACAGGTTCTCGGGCGAGGGGAAAACATCCGCCATGTTCTGGCTGGGAACAGGG
CCGCGGACGTCGGACACTGCGCTGGCCTGTTCGATGGGGCATGACAAGCATAACGTCTGGGCCGTCGGGTCATCGGATGC
AGCGATGGCCATGGCAGTGAACGCCTTGCGCGATATCCAGGGCGGGTGGGCGCTGGTCCGGGAAGGCCAATTGGTCGCGA
CTGTCCGGTATGAGGTCGGCGGCTTGATGACCTGCCGCCCGCCCGCAGAACTCGACGCCGAGATGCAGGCGCTCTACGCC
GAAGGTGAAAAGATCGACTGGATGTATGAGCCGACAGTCAGCCCCCGCTGGTTTCCCGGCTTTCCGGAGCGTCTGGCCTT
CGCCACGCTGACCTGCGCGCCCTGGCGGTGGGTGCTTGTCGCCCCGTCGGACCGGGCGCCAGACGGCTTCGTGAACGTGG
CGACAGGGCAGACGCATCCCGTCGTCTGGTAG

Upstream 100 bases:

>100_bases
GTCGCCTTGGGACTCCCCCACGAACCTTGGTGGAGGCCGTCGACATGGGCCGGTTGGTCGAGCTCTACCGGGCATCCATT
GCCGGTCCGGCGTCGACAAA

Downstream 100 bases:

>100_bases
CTGCCCAATATTTCAACCTTTGCATCTTTGCGCGGCATTCGAGGCCGGTAGAACTTGCACCTCCGCAAATTGCTCCATAC
GCTTGAGTTATTACAAGGGG

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase 2; Adenine aminase 2

Number of amino acids: Translated: 623; Mature: 622

Protein sequence:

>623_residues
MTDQPAPTDHLIRAADEVKIRQRLVRVALGHVAGDTRLRVGKLLDVHSRMWLSDQEIILSGRRIAYVGPAGSYPGGVAHE
VHEPDLMAVPGFGEVHKHIESSHVTPEWEAALVLPHGNTWTCEASHEFSNVNGPHNLEFWLTARLAGSPQKIFPLPGSAV
PPTAYEWGGGHFGYDEQAGFLNESLMVAGLDEVMDWPAVWNPENPSYDRLWGMIEATFEKRGVIEGHAAGIRDMATINAF
AAAGLASDHEAWTTEEVLDKLRRGLFMELRPHSLSEMVKGLLEAGLEDWGQFALTTDDRSCSDTLKMGATDHNVRLAISA
GLSPEVAIQMVTINPARHMRLTPWVGSLAPGRFADIVLLDDLPSVSIRQVWADGELVAEDGTYLKPIPKIDWPDWATQTV
KIDRAMMADDFAIPAKRGRDTMHAALLRPFHWDDDFITMDLPVKDGQVQRDPRRNVTKFAIVDRFSGEGKTSAMFWLGTG
PRTSDTALACSMGHDKHNVWAVGSSDAAMAMAVNALRDIQGGWALVREGQLVATVRYEVGGLMTCRPPAELDAEMQALYA
EGEKIDWMYEPTVSPRWFPGFPERLAFATLTCAPWRWVLVAPSDRAPDGFVNVATGQTHPVVW

Sequences:

>Translated_623_residues
MTDQPAPTDHLIRAADEVKIRQRLVRVALGHVAGDTRLRVGKLLDVHSRMWLSDQEIILSGRRIAYVGPAGSYPGGVAHE
VHEPDLMAVPGFGEVHKHIESSHVTPEWEAALVLPHGNTWTCEASHEFSNVNGPHNLEFWLTARLAGSPQKIFPLPGSAV
PPTAYEWGGGHFGYDEQAGFLNESLMVAGLDEVMDWPAVWNPENPSYDRLWGMIEATFEKRGVIEGHAAGIRDMATINAF
AAAGLASDHEAWTTEEVLDKLRRGLFMELRPHSLSEMVKGLLEAGLEDWGQFALTTDDRSCSDTLKMGATDHNVRLAISA
GLSPEVAIQMVTINPARHMRLTPWVGSLAPGRFADIVLLDDLPSVSIRQVWADGELVAEDGTYLKPIPKIDWPDWATQTV
KIDRAMMADDFAIPAKRGRDTMHAALLRPFHWDDDFITMDLPVKDGQVQRDPRRNVTKFAIVDRFSGEGKTSAMFWLGTG
PRTSDTALACSMGHDKHNVWAVGSSDAAMAMAVNALRDIQGGWALVREGQLVATVRYEVGGLMTCRPPAELDAEMQALYA
EGEKIDWMYEPTVSPRWFPGFPERLAFATLTCAPWRWVLVAPSDRAPDGFVNVATGQTHPVVW
>Mature_622_residues
TDQPAPTDHLIRAADEVKIRQRLVRVALGHVAGDTRLRVGKLLDVHSRMWLSDQEIILSGRRIAYVGPAGSYPGGVAHEV
HEPDLMAVPGFGEVHKHIESSHVTPEWEAALVLPHGNTWTCEASHEFSNVNGPHNLEFWLTARLAGSPQKIFPLPGSAVP
PTAYEWGGGHFGYDEQAGFLNESLMVAGLDEVMDWPAVWNPENPSYDRLWGMIEATFEKRGVIEGHAAGIRDMATINAFA
AAGLASDHEAWTTEEVLDKLRRGLFMELRPHSLSEMVKGLLEAGLEDWGQFALTTDDRSCSDTLKMGATDHNVRLAISAG
LSPEVAIQMVTINPARHMRLTPWVGSLAPGRFADIVLLDDLPSVSIRQVWADGELVAEDGTYLKPIPKIDWPDWATQTVK
IDRAMMADDFAIPAKRGRDTMHAALLRPFHWDDDFITMDLPVKDGQVQRDPRRNVTKFAIVDRFSGEGKTSAMFWLGTGP
RTSDTALACSMGHDKHNVWAVGSSDAAMAMAVNALRDIQGGWALVREGQLVATVRYEVGGLMTCRPPAELDAEMQALYAE
GEKIDWMYEPTVSPRWFPGFPERLAFATLTCAPWRWVLVAPSDRAPDGFVNVATGQTHPVVW

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=554, Percent_Identity=29.6028880866426, Blast_Score=156, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC2_JANSC (Q28MB2)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_511175.1
- ProteinModelPortal:   Q28MB2
- STRING:   Q28MB2
- GeneID:   3935705
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_3233
- eggNOG:   COG1001
- HOGENOM:   HBG299229
- OMA:   FAIVDRF
- PhylomeDB:   Q28MB2
- ProtClustDB:   CLSK820086
- BioCyc:   JSP290400:JANN_3233-MONOMER
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 68762; Mature: 68630

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQPAPTDHLIRAADEVKIRQRLVRVALGHVAGDTRLRVGKLLDVHSRMWLSDQEIILS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCCEEEE
GRRIAYVGPAGSYPGGVAHEVHEPDLMAVPGFGEVHKHIESSHVTPEWEAALVLPHGNTW
CCEEEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCCCEEEEEECCCEE
TCEASHEFSNVNGPHNLEFWLTARLAGSPQKIFPLPGSAVPPTAYEWGGGHFGYDEQAGF
EEECCCCCCCCCCCCCEEEEEEEEECCCCCEEEECCCCCCCCCCEECCCCCCCCCCCCCC
LNESLMVAGLDEVMDWPAVWNPENPSYDRLWGMIEATFEKRGVIEGHAAGIRDMATINAF
CCCCHHEEEHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
AAAGLASDHEAWTTEEVLDKLRRGLFMELRPHSLSEMVKGLLEAGLEDWGQFALTTDDRS
HHHCCCCCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCHHHHCCEEEEECCCC
CSDTLKMGATDHNVRLAISAGLSPEVAIQMVTINPARHMRLTPWVGSLAPGRFADIVLLD
CHHHHHCCCCCCCEEEEEECCCCCCEEEEEEEECCCCCEEECCCCCCCCCCCEEEEEEEC
DLPSVSIRQVWADGELVAEDGTYLKPIPKIDWPDWATQTVKIDRAMMADDFAIPAKRGRD
CCCCCCEEEEECCCEEEECCCCEECCCCCCCCCCCCCEEEEECHHHHHCCCCCCCCCCCH
TMHAALLRPFHWDDDFITMDLPVKDGQVQRDPRRNVTKFAIVDRFSGEGKTSAMFWLGTG
HHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEEECC
PRTSDTALACSMGHDKHNVWAVGSSDAAMAMAVNALRDIQGGWALVREGQLVATVRYEVG
CCCCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCEEEEEEEECC
GLMTCRPPAELDAEMQALYAEGEKIDWMYEPTVSPRWFPGFPERLAFATLTCAPWRWVLV
CEEECCCCHHCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHEEEEEECCEEEEEE
APSDRAPDGFVNVATGQTHPVVW
CCCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
TDQPAPTDHLIRAADEVKIRQRLVRVALGHVAGDTRLRVGKLLDVHSRMWLSDQEIILS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCCEEEE
GRRIAYVGPAGSYPGGVAHEVHEPDLMAVPGFGEVHKHIESSHVTPEWEAALVLPHGNTW
CCEEEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCCCEEEEEECCCEE
TCEASHEFSNVNGPHNLEFWLTARLAGSPQKIFPLPGSAVPPTAYEWGGGHFGYDEQAGF
EEECCCCCCCCCCCCCEEEEEEEEECCCCCEEEECCCCCCCCCCEECCCCCCCCCCCCCC
LNESLMVAGLDEVMDWPAVWNPENPSYDRLWGMIEATFEKRGVIEGHAAGIRDMATINAF
CCCCHHEEEHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
AAAGLASDHEAWTTEEVLDKLRRGLFMELRPHSLSEMVKGLLEAGLEDWGQFALTTDDRS
HHHCCCCCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCHHHHCCEEEEECCCC
CSDTLKMGATDHNVRLAISAGLSPEVAIQMVTINPARHMRLTPWVGSLAPGRFADIVLLD
CHHHHHCCCCCCCEEEEEECCCCCCEEEEEEEECCCCCEEECCCCCCCCCCCEEEEEEEC
DLPSVSIRQVWADGELVAEDGTYLKPIPKIDWPDWATQTVKIDRAMMADDFAIPAKRGRD
CCCCCCEEEEECCCEEEECCCCEECCCCCCCCCCCCCEEEEECHHHHHCCCCCCCCCCCH
TMHAALLRPFHWDDDFITMDLPVKDGQVQRDPRRNVTKFAIVDRFSGEGKTSAMFWLGTG
HHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEEECC
PRTSDTALACSMGHDKHNVWAVGSSDAAMAMAVNALRDIQGGWALVREGQLVATVRYEVG
CCCCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCEEEEEEEECC
GLMTCRPPAELDAEMQALYAEGEKIDWMYEPTVSPRWFPGFPERLAFATLTCAPWRWVLV
CEEECCCCHHCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHEEEEEECCEEEEEE
APSDRAPDGFVNVATGQTHPVVW
CCCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA