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The map label for this gene is tldD [H]

Identifier: 89055647

GI number: 89055647

Start: 3195755

End: 3197179

Strand: Direct

Name: tldD [H]

Synonym: Jann_3156

Alternate gene names: 89055647

Gene position: 3195755-3197179 (Clockwise)

Preceding gene: 89055636

Following gene: 89055648

Centisome position: 74.01

GC content: 66.6

Gene sequence:

>1425_bases
ATGTCCGACACCGCACCGTTTCGCCCGTTCGAGACCCACCTAGATGAAGAGGCCGCCCTGCGCGTCCTGCGCCAGGCCAC
AGCAGGCGCGGATGATGGGGAGTTGTTTCTGGAGCGCCGCAGGTCCGAGGTTCTGGTGTTTGACGATGGCCGGGTGAAGA
ACGCCTCCTATGACGCGGCGCAGGGCTTCGGTCTGCGCGCCGTGAAGGGAGAGGTCGCGGGCTACGCCCATTCCACAGAA
ATCTCGGAAGCCGCGGTGTTGCGTGCCGCAGAAACCGCACGTCTGGCCGTGGGTGACGGCGGCGGCACATTGGCCGATGC
GCCCCGGGGCACGAACGAGAAACTCTACACCGACGCGGACCCCATGGCAGGCGCGGAGTTTGGCGTGAAGCTGGAGACTT
TGGCCGAGATCGACGCCTTCGCCCGCGCCTTGGACACCCGCGTCGTGCAGGTCAGCGCGTCCATGGCCGCCAGCTTGCAG
GAGGTGGTGATCCTGCGGCCCGAAGGAGGATCTGTTACTGACGCACGGCCCATGGTGCGCCTGAACGTGTCCGTGATCGT
TGAGGAAAACGGCCGCCGCGAAAGCGGATCGGCGGGCGGCGGCGGGCGTGTGGGGTTGGAAGGCCTGATGACCCGCGCCC
ATTGGGAAAGCGTTGCGAAAGAGGCGTTGCGCGTGGCGGTCGTCAACCTGTCGGCGGAACCCGCGCCCGCAGGCGTGATG
GACGTGGCCTTGGGCAGTGGCTGGCCCGGCATATTGCTTCACGAGGCCATCGGCCACGGGTTGGAGGGCGACTTCAACCG
CAAGAAACAAAGCGCATTTGCCGGGCTGATGGGACAGCGCATCGCCTCCAAGGGCGTGACGGTGCTGGACGACGGCACAA
TCCCGGACCGGCGCGGCTCGATCAGCGTGGACGATGAGGGCACCCCGTCGGAAGCCACGACCCTGATCGAGGATGGCGTT
CTGGTCAGCTACATGCAGGACCGCCAATCCGCGCGCCTGATGGGCGTCGCGCCCACCGGCAACGGACGGCGCGAAAGCTA
TGCCCACGCGCCGATGACACGGATGACCAATACCTACATGTTGGGCGGCGACGTGGCCCCCGGGGACATCGTGGCAGACG
TGAAAGACGGCATCTACGCGGTGGGCTTCGGCGGCGGTCAGGTGGACATCACGAACGGCAAGTTCGTCTTCTCCTGTACG
GAAGCCTACCGTGTGAAAAACGGCATCGTTGGCGCGCCCGTCAAAGGGGCCACGCTGATCGGCGACGGCGCGACCGCATT
GCAGCAGATCCGCGCCATCGGCAATGACATGGCGCTGGACCCGGGCATGGGCAATTGCGGCAAACAGGGCCAGTGGGTGC
CGGTGGGTGTCGGCCAGCCGACGCTGTTGATCGGCGGGCTGACCGTGGGCGGCTCCGCTGCGTGA

Upstream 100 bases:

>100_bases
AAGGCAGTGGCCTAAATTGTCTCACCCAAAGGGCCGAGACGGGGTGTCGCACCCGCCGCAAAACACCCTATGTATAGCCA
AACCGCGAGGAGCCTTTTGC

Downstream 100 bases:

>100_bases
CGGCGGCCCCCGTGAAAACCTTCACCCCCGCCCTGCGCAGCAGGCCCTACGGCCACCGGTACCTGCGGGCGGGAAGGGTC
GTGCTGATCGCGCTCGTCAC

Product: microcin-processing peptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MSDTAPFRPFETHLDEEAALRVLRQATAGADDGELFLERRRSEVLVFDDGRVKNASYDAAQGFGLRAVKGEVAGYAHSTE
ISEAAVLRAAETARLAVGDGGGTLADAPRGTNEKLYTDADPMAGAEFGVKLETLAEIDAFARALDTRVVQVSASMAASLQ
EVVILRPEGGSVTDARPMVRLNVSVIVEENGRRESGSAGGGGRVGLEGLMTRAHWESVAKEALRVAVVNLSAEPAPAGVM
DVALGSGWPGILLHEAIGHGLEGDFNRKKQSAFAGLMGQRIASKGVTVLDDGTIPDRRGSISVDDEGTPSEATTLIEDGV
LVSYMQDRQSARLMGVAPTGNGRRESYAHAPMTRMTNTYMLGGDVAPGDIVADVKDGIYAVGFGGGQVDITNGKFVFSCT
EAYRVKNGIVGAPVKGATLIGDGATALQQIRAIGNDMALDPGMGNCGKQGQWVPVGVGQPTLLIGGLTVGGSAA

Sequences:

>Translated_474_residues
MSDTAPFRPFETHLDEEAALRVLRQATAGADDGELFLERRRSEVLVFDDGRVKNASYDAAQGFGLRAVKGEVAGYAHSTE
ISEAAVLRAAETARLAVGDGGGTLADAPRGTNEKLYTDADPMAGAEFGVKLETLAEIDAFARALDTRVVQVSASMAASLQ
EVVILRPEGGSVTDARPMVRLNVSVIVEENGRRESGSAGGGGRVGLEGLMTRAHWESVAKEALRVAVVNLSAEPAPAGVM
DVALGSGWPGILLHEAIGHGLEGDFNRKKQSAFAGLMGQRIASKGVTVLDDGTIPDRRGSISVDDEGTPSEATTLIEDGV
LVSYMQDRQSARLMGVAPTGNGRRESYAHAPMTRMTNTYMLGGDVAPGDIVADVKDGIYAVGFGGGQVDITNGKFVFSCT
EAYRVKNGIVGAPVKGATLIGDGATALQQIRAIGNDMALDPGMGNCGKQGQWVPVGVGQPTLLIGGLTVGGSAA
>Mature_473_residues
SDTAPFRPFETHLDEEAALRVLRQATAGADDGELFLERRRSEVLVFDDGRVKNASYDAAQGFGLRAVKGEVAGYAHSTEI
SEAAVLRAAETARLAVGDGGGTLADAPRGTNEKLYTDADPMAGAEFGVKLETLAEIDAFARALDTRVVQVSASMAASLQE
VVILRPEGGSVTDARPMVRLNVSVIVEENGRRESGSAGGGGRVGLEGLMTRAHWESVAKEALRVAVVNLSAEPAPAGVMD
VALGSGWPGILLHEAIGHGLEGDFNRKKQSAFAGLMGQRIASKGVTVLDDGTIPDRRGSISVDDEGTPSEATTLIEDGVL
VSYMQDRQSARLMGVAPTGNGRRESYAHAPMTRMTNTYMLGGDVAPGDIVADVKDGIYAVGFGGGQVDITNGKFVFSCTE
AYRVKNGIVGAPVKGATLIGDGATALQQIRAIGNDMALDPGMGNCGKQGQWVPVGVGQPTLLIGGLTVGGSAA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=448, Percent_Identity=52.4553571428571, Blast_Score=441, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 49224; Mature: 49093

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTAPFRPFETHLDEEAALRVLRQATAGADDGELFLERRRSEVLVFDDGRVKNASYDAA
CCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCHH
QGFGLRAVKGEVAGYAHSTEISEAAVLRAAETARLAVGDGGGTLADAPRGTNEKLYTDAD
CCCCEEEECCHHCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCEEECCC
PMAGAEFGVKLETLAEIDAFARALDTRVVQVSASMAASLQEVVILRPEGGSVTDARPMVR
CCCCCCCCEEHHHHHHHHHHHHHHHHHEEEEHHHHHHCCEEEEEECCCCCCCCCCCCEEE
LNVSVIVEENGRRESGSAGGGGRVGLEGLMTRAHWESVAKEALRVAVVNLSAEPAPAGVM
EEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEE
DVALGSGWPGILLHEAIGHGLEGDFNRKKQSAFAGLMGQRIASKGVTVLDDGTIPDRRGS
EECCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCC
ISVDDEGTPSEATTLIEDGVLVSYMQDRQSARLMGVAPTGNGRRESYAHAPMTRMTNTYM
EEECCCCCCHHHHHHHHCCEEEEEHHCCCCCEEEEECCCCCCCCCCCCCCCHHHCCCEEE
LGGDVAPGDIVADVKDGIYAVGFGGGQVDITNGKFVFSCTEAYRVKNGIVGAPVKGATLI
ECCCCCCCCEEEECCCCEEEEEECCCEEEEECCEEEEEEHHHHHHHCCCCCCCCCCCEEE
GDGATALQQIRAIGNDMALDPGMGNCGKQGQWVPVGVGQPTLLIGGLTVGGSAA
CCCHHHHHHHHHHCCCCEECCCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCC
>Mature Secondary Structure 
SDTAPFRPFETHLDEEAALRVLRQATAGADDGELFLERRRSEVLVFDDGRVKNASYDAA
CCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCHH
QGFGLRAVKGEVAGYAHSTEISEAAVLRAAETARLAVGDGGGTLADAPRGTNEKLYTDAD
CCCCEEEECCHHCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCEEECCC
PMAGAEFGVKLETLAEIDAFARALDTRVVQVSASMAASLQEVVILRPEGGSVTDARPMVR
CCCCCCCCEEHHHHHHHHHHHHHHHHHEEEEHHHHHHCCEEEEEECCCCCCCCCCCCEEE
LNVSVIVEENGRRESGSAGGGGRVGLEGLMTRAHWESVAKEALRVAVVNLSAEPAPAGVM
EEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEE
DVALGSGWPGILLHEAIGHGLEGDFNRKKQSAFAGLMGQRIASKGVTVLDDGTIPDRRGS
EECCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCC
ISVDDEGTPSEATTLIEDGVLVSYMQDRQSARLMGVAPTGNGRRESYAHAPMTRMTNTYM
EEECCCCCCHHHHHHHHCCEEEEEHHCCCCCEEEEECCCCCCCCCCCCCCCHHHCCCEEE
LGGDVAPGDIVADVKDGIYAVGFGGGQVDITNGKFVFSCTEAYRVKNGIVGAPVKGATLI
ECCCCCCCCEEEECCCCEEEEEECCCEEEEECCEEEEEEHHHHHHHCCCCCCCCCCCEEE
GDGATALQQIRAIGNDMALDPGMGNCGKQGQWVPVGVGQPTLLIGGLTVGGSAA
CCCHHHHHHHHHHCCCCEECCCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]