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The map label for this gene is des [H]

Identifier: 89055486

GI number: 89055486

Start: 3015304

End: 3016350

Strand: Direct

Name: des [H]

Synonym: Jann_2995

Alternate gene names: 89055486

Gene position: 3015304-3016350 (Clockwise)

Preceding gene: 89055482

Following gene: 89055488

Centisome position: 69.83

GC content: 58.93

Gene sequence:

>1047_bases
ATGCACGCCACATCGTCCCTTCCCGAGATCACCCCAACCTACCGGCAGGAGGCGGAGCGAGAGATTCGTCGCTTCACGCG
CGATTGGACCAAACGCGATGATCGTTTGGCGGCCGTCGGCTATTGCCTGACATTCGTGGTTTTTGGCCTGTCCCTCACGC
TGGCTTTGCTCGCCTGGCCCAACCCCTGGCTCATGGCGCCCTTGATCGTGGTGAACGCTTTTGCCGGTGTCCGGCTTTAC
GTGTTGCAGCACGATGCGGGACATAATTCGCTGTTTTCGACCTCTCGCCGCAACACTTGGGCGGGGCACGGGCTGAGTGT
GTTCACCCTCACCCCATTCGCCGTGATGCAGCACAACCACAACGAACATCACAGCCATCTCGGCAATCTGGAAGAGCGGC
ATTCAACCGAGATTTTCACAATGACCTTAAGGGAGTGGCAGGAGGCAGGTATCTGGAAACGGTTGATCTATCGCCTCTAC
CGCAACCCGTTTCTAATGGTCCCGTTTGGCGGGATCTTCACCTATGCCATCGCATATCGCTGGCCCAAGAATGCCGCGAA
AGTCGCTCCATTTCAGGTGATCGCCCATAATCTGGGCCTCGCCGCGTGGATCTTCGCGCTGTGGATGATCGCGGGCGCGC
CGGCGCTCATCATCTATGCATCCACCATCTTCGCGGCGAGCTGCATCGGGGTTTTGCTCGTCTATTTGCAGCATAACTTT
GAGGACACATGGTGGGACCGCAAACCATCGCTCAACCCCGCGCGCGCCGCGCTGCAAGGGTCGTCGGCGCTTGACCTGGG
GTGGTGGTTTGACCTTGCCGTGGCCAACATCACCTACCACGACATTCACCATTTCAACGCGAATATCCCCAGCTATCGCC
TGCGCGCGTGCCACGTCGCCCTGCGGCAGCATTATGAGGTGCAGACCATCGGTTGGGGGGAGGCATTGCGTTCGTTCACA
TTGAAATTGTGGGATGAGGATCAGGGGCGTCTGGTGGCCTTCCCGAAACCACAAGAGCAACGCGTTCCGCCCGTCCCGGC
GAAATAA

Upstream 100 bases:

>100_bases
TTTCAGAATTGAACCATAGGTATCTGGTCGACACACAAACCCACCCATCTACCTGAAAAGACCCAAATTAAAACAAACCC
TAGAGACCTGGACCGGACCC

Downstream 100 bases:

>100_bases
AACAGCGCCCGCAATGGGCTAAGCCGCCACTGCGCGGCGCACCATGTCCCAGTAAATCGCCTCCACATCCGTGCGGGTCA
GGCGCCCGTCGTCGCGGAAC

Product: fatty acid desaturase

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MHATSSLPEITPTYRQEAEREIRRFTRDWTKRDDRLAAVGYCLTFVVFGLSLTLALLAWPNPWLMAPLIVVNAFAGVRLY
VLQHDAGHNSLFSTSRRNTWAGHGLSVFTLTPFAVMQHNHNEHHSHLGNLEERHSTEIFTMTLREWQEAGIWKRLIYRLY
RNPFLMVPFGGIFTYAIAYRWPKNAAKVAPFQVIAHNLGLAAWIFALWMIAGAPALIIYASTIFAASCIGVLLVYLQHNF
EDTWWDRKPSLNPARAALQGSSALDLGWWFDLAVANITYHDIHHFNANIPSYRLRACHVALRQHYEVQTIGWGEALRSFT
LKLWDEDQGRLVAFPKPQEQRVPPVPAK

Sequences:

>Translated_348_residues
MHATSSLPEITPTYRQEAEREIRRFTRDWTKRDDRLAAVGYCLTFVVFGLSLTLALLAWPNPWLMAPLIVVNAFAGVRLY
VLQHDAGHNSLFSTSRRNTWAGHGLSVFTLTPFAVMQHNHNEHHSHLGNLEERHSTEIFTMTLREWQEAGIWKRLIYRLY
RNPFLMVPFGGIFTYAIAYRWPKNAAKVAPFQVIAHNLGLAAWIFALWMIAGAPALIIYASTIFAASCIGVLLVYLQHNF
EDTWWDRKPSLNPARAALQGSSALDLGWWFDLAVANITYHDIHHFNANIPSYRLRACHVALRQHYEVQTIGWGEALRSFT
LKLWDEDQGRLVAFPKPQEQRVPPVPAK
>Mature_348_residues
MHATSSLPEITPTYRQEAEREIRRFTRDWTKRDDRLAAVGYCLTFVVFGLSLTLALLAWPNPWLMAPLIVVNAFAGVRLY
VLQHDAGHNSLFSTSRRNTWAGHGLSVFTLTPFAVMQHNHNEHHSHLGNLEERHSTEIFTMTLREWQEAGIWKRLIYRLY
RNPFLMVPFGGIFTYAIAYRWPKNAAKVAPFQVIAHNLGLAAWIFALWMIAGAPALIIYASTIFAASCIGVLLVYLQHNF
EDTWWDRKPSLNPARAALQGSSALDLGWWFDLAVANITYHDIHHFNANIPSYRLRACHVALRQHYEVQTIGWGEALRSFT
LKLWDEDQGRLVAFPKPQEQRVPPVPAK

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 39896; Mature: 39896

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHATSSLPEITPTYRQEAEREIRRFTRDWTKRDDRLAAVGYCLTFVVFGLSLTLALLAWP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
NPWLMAPLIVVNAFAGVRLYVLQHDAGHNSLFSTSRRNTWAGHGLSVFTLTPFAVMQHNH
CCHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHCCCCCCCCCCCEEEEEECHHHHHHCCC
NEHHSHLGNLEERHSTEIFTMTLREWQEAGIWKRLIYRLYRNPFLMVPFGGIFTYAIAYR
CHHHHHHCCHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHH
WPKNAAKVAPFQVIAHNLGLAAWIFALWMIAGAPALIIYASTIFAASCIGVLLVYLQHNF
CCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
EDTWWDRKPSLNPARAALQGSSALDLGWWFDLAVANITYHDIHHFNANIPSYRLRACHVA
CCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHH
LRQHYEVQTIGWGEALRSFTLKLWDEDQGRLVAFPKPQEQRVPPVPAK
HHHCCCEEECCHHHHHHHHHHEEEECCCCCEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MHATSSLPEITPTYRQEAEREIRRFTRDWTKRDDRLAAVGYCLTFVVFGLSLTLALLAWP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
NPWLMAPLIVVNAFAGVRLYVLQHDAGHNSLFSTSRRNTWAGHGLSVFTLTPFAVMQHNH
CCHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHCCCCCCCCCCCEEEEEECHHHHHHCCC
NEHHSHLGNLEERHSTEIFTMTLREWQEAGIWKRLIYRLYRNPFLMVPFGGIFTYAIAYR
CHHHHHHCCHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHH
WPKNAAKVAPFQVIAHNLGLAAWIFALWMIAGAPALIIYASTIFAASCIGVLLVYLQHNF
CCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
EDTWWDRKPSLNPARAALQGSSALDLGWWFDLAVANITYHDIHHFNANIPSYRLRACHVA
CCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHH
LRQHYEVQTIGWGEALRSFTLKLWDEDQGRLVAFPKPQEQRVPPVPAK
HHHCCCEEECCHHHHHHHHHHEEEECCCCCEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]