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The map label for this gene is siaT [H]

Identifier: 89055370

GI number: 89055370

Start: 2898866

End: 2901085

Strand: Direct

Name: siaT [H]

Synonym: Jann_2879

Alternate gene names: 89055370

Gene position: 2898866-2901085 (Clockwise)

Preceding gene: 89055369

Following gene: 89055371

Centisome position: 67.13

GC content: 63.51

Gene sequence:

>2220_bases
ATGGCAGATCAGACCGCACAGCAGGACGACACGCGCACGTTGACCGAAGAGGAACTTGCCGAGATCGAGCGCAAGTATGA
CGAGGGCGCCGCCACTCGGCCCGTCGGCCCGCGGCTGGGGTTGGCCCTGCGCGCCGTGGCGCTGACATTCGCCGTCTACC
ATTACCTGACCGCAGGCTTCGCCCTGCCCGCCGACCACTGGCACATGGGCTGGCATCTGGCGGGCCTGTTCATCCTGACC
TACGCCTTCTTCCCCCTCTTCAAGACCAAACGCGCGTTCGAGATGCGCCCCAGCGCGTTCCGCGTCGGCAATGTGCCGAT
CTTCGATTTCGTCCTGATGATCCTTGGCGTCGGCGCGGCCCTTTATCTGGGGCTCGCGTGGCGCGGCATCCCCGGGCTCG
GCATCGACGAGCAGACGTTTCGCATGGGCAACCCGAACAATTACGACATCTTCTTCGGCCTCGTGCTGATCATCCTGGTC
CTCGACATCGCGCGCCGGACATTGGGCTGGATCCTGCCCGCGATCATCTGCGTCTTCATCGCCTATGCGCTGTTCGGCCC
GTGGTTTCCGGGCGTGTTGCAACATCCCGGCGTGCGGTTCCGCACCTTCGTGTCGTCGATGTATTTCCCGCAGGAAGGCA
TCTTTGGCGTCACGCTCTGGGTCGTGTCCACCATCGTCTTCCACTTCGTGCTGTTCGGCGTGATCGCGCAGCGCACGGGC
CTGGGGCAGTTGTTCATCGACAACGCGACGATCCTTGCGGGGCGCTATACGGGCGGACCTGCGAAAGTGTCCGTCGTGTC
CTCGGCCTTTTTTGGCACGATCTCGGGCAGTTCAGTGGCCAACACCGTCTCCACCGGCGCGCTGACCATCCCCAACATGA
AACGGCTGGGGTATCCGGGCCATTTCGCGGGCGGGGTGGAGGCAGCCTCCTCCGCCGGTGGCCAGATCACGCCGCCGATC
ATGGGCGCGGCCGCCTTCATCATGGCCGAATTCCTGGAGGTCCCCTACACCACCATCGTCATCGCCGCGATCTTCCCGGC
GCTGCTGCACTATGTGGGCGTCTTCACCGTTGTGCACCTGATGGCCAAAAAGCTGGACCTTAAGGGCCTGACCAAAGACG
CGATGCCGCAATTCAAGGCGGTCTGGAAGGAGGGATGGGCCAATATCGTGCCGCTGGTGGCGCTGCTGGTCGTCCTCTTC
TCCGGCTACACGCCTTATATGTCGGCCTTCTGCGGGATATCCGTGGCGATCATCGCGGGCATGAGCCGTGTGCGGGAGCC
GCTGTCGCTGATCTATGCCATAGCCTTCATCGCCTTCGTGATCTGGAAATACATGGGTGGCGGGTTTGACATCGGCATGT
CGGGCATCCTGATCGCCTGCGCCGTCTTGGGGTCGTTCAACCCGCAGGCCCGGGTGAAGCTGCCGGAAATGGCCACCACG
TTCGAGACGGGCGTGAAATACGCGCTGGCCGTGGGGGCGGCCTCGGCGGCGGTGGGCATCGTGGTGGGGGTGATCAACAC
CACGGGCATCGGCTTCCGCATCGGCTTCATGGTGACGCAGGGCGCGTCCAATCTGGGCTCCGACCTGCATGTGCTGTTTG
CCATGACAGGGCTGCAATTCATCACCGTGGAAGATCTGACGCTGTTCATCAGCCTCGTCTTCATCGCCGTGGCCTGCATC
CTGATGGGCGCGGGCGTGCCGACGACGGCGCTCTATATCATGCTGGTCTCCGTCGCGCAGCCGGCGCTGTCGCAACTGGG
CATTCCGCCCATCGCGTCGCATATGTTCGTACTCTATTACGGGGTCGTGGCGGAGATCACGCCACCGGTCTGCACATCGG
CCTATGCGGCAGCAGCCATCGCCAATTCCAACCCGTTCAGAACCGGCATATCCGCCTTCACCCTGGGCCTTGGCAAGGTG
GTGGCGCCGATGGCCTTCGTCTATGCGCCGGTCCTGTTGTTCGTATCCTCAACCGGGTTCGACTTCTGGGAATTCACCTA
CACCGCCGCCAGTTGCATCGCGGGGGTCGTGGCGCTGTCCACGGCGGTGGTCGGCTACTTCTACGCGCCGGTGAATATCG
CCTTCCGGTGGTTGCTGGCGTTTGCCGGGCTGGTCTTCATCGCGCCATCCATTCAGGCCGATATCTTCGCGCTGGTCCTG
TGCACGCCGGTGATCATCAGCCAGTTGGTGAAGCGCCGCACGGTGGCCCCAGCCGGATGA

Upstream 100 bases:

>100_bases
CGGGCCTGATGGAGTGATCGCTCCACCCGTTTGAAGACTTCTGGGGCGTCCGAAGCGGGCGCCCCAGTCACAAGAGATAC
CAGAACCGGCAGGGGCATCG

Downstream 100 bases:

>100_bases
ACGACGACACCACGAGTGTTCTGGGCGCGGGCATCGTGGGCCTGTGTTGCGCGCTGTCCTTGGCCGAGCGGGGGCACAAG
GTGCGCGTGATTGACCGTGA

Product: TRAP transporter, 4TM/12TM fusion protein

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 739; Mature: 738

Protein sequence:

>739_residues
MADQTAQQDDTRTLTEEELAEIERKYDEGAATRPVGPRLGLALRAVALTFAVYHYLTAGFALPADHWHMGWHLAGLFILT
YAFFPLFKTKRAFEMRPSAFRVGNVPIFDFVLMILGVGAALYLGLAWRGIPGLGIDEQTFRMGNPNNYDIFFGLVLIILV
LDIARRTLGWILPAIICVFIAYALFGPWFPGVLQHPGVRFRTFVSSMYFPQEGIFGVTLWVVSTIVFHFVLFGVIAQRTG
LGQLFIDNATILAGRYTGGPAKVSVVSSAFFGTISGSSVANTVSTGALTIPNMKRLGYPGHFAGGVEAASSAGGQITPPI
MGAAAFIMAEFLEVPYTTIVIAAIFPALLHYVGVFTVVHLMAKKLDLKGLTKDAMPQFKAVWKEGWANIVPLVALLVVLF
SGYTPYMSAFCGISVAIIAGMSRVREPLSLIYAIAFIAFVIWKYMGGGFDIGMSGILIACAVLGSFNPQARVKLPEMATT
FETGVKYALAVGAASAAVGIVVGVINTTGIGFRIGFMVTQGASNLGSDLHVLFAMTGLQFITVEDLTLFISLVFIAVACI
LMGAGVPTTALYIMLVSVAQPALSQLGIPPIASHMFVLYYGVVAEITPPVCTSAYAAAAIANSNPFRTGISAFTLGLGKV
VAPMAFVYAPVLLFVSSTGFDFWEFTYTAASCIAGVVALSTAVVGYFYAPVNIAFRWLLAFAGLVFIAPSIQADIFALVL
CTPVIISQLVKRRTVAPAG

Sequences:

>Translated_739_residues
MADQTAQQDDTRTLTEEELAEIERKYDEGAATRPVGPRLGLALRAVALTFAVYHYLTAGFALPADHWHMGWHLAGLFILT
YAFFPLFKTKRAFEMRPSAFRVGNVPIFDFVLMILGVGAALYLGLAWRGIPGLGIDEQTFRMGNPNNYDIFFGLVLIILV
LDIARRTLGWILPAIICVFIAYALFGPWFPGVLQHPGVRFRTFVSSMYFPQEGIFGVTLWVVSTIVFHFVLFGVIAQRTG
LGQLFIDNATILAGRYTGGPAKVSVVSSAFFGTISGSSVANTVSTGALTIPNMKRLGYPGHFAGGVEAASSAGGQITPPI
MGAAAFIMAEFLEVPYTTIVIAAIFPALLHYVGVFTVVHLMAKKLDLKGLTKDAMPQFKAVWKEGWANIVPLVALLVVLF
SGYTPYMSAFCGISVAIIAGMSRVREPLSLIYAIAFIAFVIWKYMGGGFDIGMSGILIACAVLGSFNPQARVKLPEMATT
FETGVKYALAVGAASAAVGIVVGVINTTGIGFRIGFMVTQGASNLGSDLHVLFAMTGLQFITVEDLTLFISLVFIAVACI
LMGAGVPTTALYIMLVSVAQPALSQLGIPPIASHMFVLYYGVVAEITPPVCTSAYAAAAIANSNPFRTGISAFTLGLGKV
VAPMAFVYAPVLLFVSSTGFDFWEFTYTAASCIAGVVALSTAVVGYFYAPVNIAFRWLLAFAGLVFIAPSIQADIFALVL
CTPVIISQLVKRRTVAPAG
>Mature_738_residues
ADQTAQQDDTRTLTEEELAEIERKYDEGAATRPVGPRLGLALRAVALTFAVYHYLTAGFALPADHWHMGWHLAGLFILTY
AFFPLFKTKRAFEMRPSAFRVGNVPIFDFVLMILGVGAALYLGLAWRGIPGLGIDEQTFRMGNPNNYDIFFGLVLIILVL
DIARRTLGWILPAIICVFIAYALFGPWFPGVLQHPGVRFRTFVSSMYFPQEGIFGVTLWVVSTIVFHFVLFGVIAQRTGL
GQLFIDNATILAGRYTGGPAKVSVVSSAFFGTISGSSVANTVSTGALTIPNMKRLGYPGHFAGGVEAASSAGGQITPPIM
GAAAFIMAEFLEVPYTTIVIAAIFPALLHYVGVFTVVHLMAKKLDLKGLTKDAMPQFKAVWKEGWANIVPLVALLVVLFS
GYTPYMSAFCGISVAIIAGMSRVREPLSLIYAIAFIAFVIWKYMGGGFDIGMSGILIACAVLGSFNPQARVKLPEMATTF
ETGVKYALAVGAASAAVGIVVGVINTTGIGFRIGFMVTQGASNLGSDLHVLFAMTGLQFITVEDLTLFISLVFIAVACIL
MGAGVPTTALYIMLVSVAQPALSQLGIPPIASHMFVLYYGVVAEITPPVCTSAYAAAAIANSNPFRTGISAFTLGLGKVV
APMAFVYAPVLLFVSSTGFDFWEFTYTAASCIAGVVALSTAVVGYFYAPVNIAFRWLLAFAGLVFIAPSIQADIFALVLC
TPVIISQLVKRRTVAPAG

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG4666

COG function: function code R; TRAP-type uncharacterized transport system, fused permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 78976; Mature: 78845

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADQTAQQDDTRTLTEEELAEIERKYDEGAATRPVGPRLGLALRAVALTFAVYHYLTAGF
CCCCCCCCCCHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
ALPADHWHMGWHLAGLFILTYAFFPLFKTKRAFEMRPSAFRVGNVPIFDFVLMILGVGAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHH
LYLGLAWRGIPGLGIDEQTFRMGNPNNYDIFFGLVLIILVLDIARRTLGWILPAIICVFI
HHHHHHHCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYALFGPWFPGVLQHPGVRFRTFVSSMYFPQEGIFGVTLWVVSTIVFHFVLFGVIAQRTG
HHHHHCCCCCHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
LGQLFIDNATILAGRYTGGPAKVSVVSSAFFGTISGSSVANTVSTGALTIPNMKRLGYPG
CCEEEECCCEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCEECCCHHHCCCCC
HFAGGVEAASSAGGQITPPIMGAAAFIMAEFLEVPYTTIVIAAIFPALLHYVGVFTVVHL
CCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
MAKKLDLKGLTKDAMPQFKAVWKEGWANIVPLVALLVVLFSGYTPYMSAFCGISVAIIAG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
MSRVREPLSLIYAIAFIAFVIWKYMGGGFDIGMSGILIACAVLGSFNPQARVKLPEMATT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCHHHHH
FETGVKYALAVGAASAAVGIVVGVINTTGIGFRIGFMVTQGASNLGSDLHVLFAMTGLQF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHCCCHHHHHHHHHCCCE
ITVEDLTLFISLVFIAVACILMGAGVPTTALYIMLVSVAQPALSQLGIPPIASHMFVLYY
EEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
GVVAEITPPVCTSAYAAAAIANSNPFRTGISAFTLGLGKVVAPMAFVYAPVLLFVSSTGF
HHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DFWEFTYTAASCIAGVVALSTAVVGYFYAPVNIAFRWLLAFAGLVFIAPSIQADIFALVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
CTPVIISQLVKRRTVAPAG
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ADQTAQQDDTRTLTEEELAEIERKYDEGAATRPVGPRLGLALRAVALTFAVYHYLTAGF
CCCCCCCCCHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
ALPADHWHMGWHLAGLFILTYAFFPLFKTKRAFEMRPSAFRVGNVPIFDFVLMILGVGAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHH
LYLGLAWRGIPGLGIDEQTFRMGNPNNYDIFFGLVLIILVLDIARRTLGWILPAIICVFI
HHHHHHHCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYALFGPWFPGVLQHPGVRFRTFVSSMYFPQEGIFGVTLWVVSTIVFHFVLFGVIAQRTG
HHHHHCCCCCHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
LGQLFIDNATILAGRYTGGPAKVSVVSSAFFGTISGSSVANTVSTGALTIPNMKRLGYPG
CCEEEECCCEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCEECCCHHHCCCCC
HFAGGVEAASSAGGQITPPIMGAAAFIMAEFLEVPYTTIVIAAIFPALLHYVGVFTVVHL
CCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
MAKKLDLKGLTKDAMPQFKAVWKEGWANIVPLVALLVVLFSGYTPYMSAFCGISVAIIAG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
MSRVREPLSLIYAIAFIAFVIWKYMGGGFDIGMSGILIACAVLGSFNPQARVKLPEMATT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCHHHHH
FETGVKYALAVGAASAAVGIVVGVINTTGIGFRIGFMVTQGASNLGSDLHVLFAMTGLQF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHCCCHHHHHHHHHCCCE
ITVEDLTLFISLVFIAVACILMGAGVPTTALYIMLVSVAQPALSQLGIPPIASHMFVLYY
EEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
GVVAEITPPVCTSAYAAAAIANSNPFRTGISAFTLGLGKVVAPMAFVYAPVLLFVSSTGF
HHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DFWEFTYTAASCIAGVVALSTAVVGYFYAPVNIAFRWLLAFAGLVFIAPSIQADIFALVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
CTPVIISQLVKRRTVAPAG
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]