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The map label for this gene is yngJ [H]

Identifier: 89055302

GI number: 89055302

Start: 2825779

End: 2827014

Strand: Reverse

Name: yngJ [H]

Synonym: Jann_2811

Alternate gene names: 89055302

Gene position: 2827014-2825779 (Counterclockwise)

Preceding gene: 89055303

Following gene: 89055301

Centisome position: 65.47

GC content: 60.28

Gene sequence:

>1236_bases
ATGGATCTGGGCGTCTCCGACAGGGTGAAGCCGCTGGTGGAGGCGGTCCGGCGCATGGTGCGCGACGACATTGCGCCACT
TGATATGGAATACCACGCGGAGGTCGGCCAGCACCCTTCAGGCGATCGCTTCGCCATGACGGACCGCCAGATAGAGATCC
TCAAGACGTTGAAAGATAAGGCGAAAGGACAAGGGCTCTGGAATTTCTGGCTGACGGATTCGCAGGACGGCTACGGGCTG
TCGACCGTCGAATACGCCTATCTGGCCGAGGAGATGGGCGCGGTATCGATCGCGCCTGAGATATTCAACTGCAACGCGCC
AGACACCGGCAACATGGAAGTGTTGGAGCGGTATGGATCGGAGGCGCAACGGACGCGATGGTTGCCGGATCTGATGGCCG
GAGTGAGCCGATCTGCATACCTGATGACAGAGCCGTCCGTCGCATCGTCAGATGCAACTCAAATTTCATTAAAATGCGAA
CGACAGGGTGAAGACTACGTCCTAAACGGCGAGAAATATTGGGCAACGGGTGCCGGGGATCCGCGGTGTGCGCTCTATAT
CGTGATGGTTTGCACCGATCCCGGCGCGGCGAAACACGCGCGGCATTCGATGCTGCTGATCCCCTCCGATGCCGCTGGGA
TCGAGACCCTGCGTCCAATGCAGGTGTTTGGCCAAGACGATGCGCCCCACGGGCACATGCATATCCGTTTCACCGACGTT
CGCGTGCCGATAGATGCGATGGTGCTGGGAGAAGGGCGCGGCTTTGAAGTGGCGCAGGGACGGCTCGGCCCGGGGCGCAT
TCACCACTGCATGCGGGCCATCGGGCGAGCCGAGTATGCCCTTGAACTGATGGTAAAAAGAGGGCTGACGCGCGAAGCAT
TTGGCAAGCCGCTGGTCGAATTGGGGGCGAATTACGACATCATCGCCAATGCGCGCATCGACATCGAGATGACGCGGCTC
CTGTGCCTGAAGGCGGCGTGGATGATGGATCATGCGGGCGTCCGCGCCGCACAACCGTGGATCTCAAAGGTCAAGGTGCA
GGCACCGTTGATGGCCTTGCAAGTGGTTGATGAAGCGATGCAAATGCACGGAGCGACCGGGCTGAGCCAGGATACGCCTC
TGTCTCGCATCTGGGCGGATCTGAGGACTTTGCGCCTTGCGGATGGTCCGGACGCTGTCCATCGCAGGCAGGTCGCCCGT
GCCGAGCTGCGCAAACATACCAATACCTCCCAATGA

Upstream 100 bases:

>100_bases
CGGGCCAAGGGATCGGAGCGGTGAAATCAGTGGGCCCTGCGGCGGCGCTGGTGGATCGGATTGCCGCAGAATACGCGGCG
GCCCGGGAGGGGTTGTTGTA

Downstream 100 bases:

>100_bases
CGGACATGGAGCTTGCGCGCATTGAGCGCTGGCTGGAGGTGAATGTCGGTCTGCAAGGCACGGTAACCGCACGTAAATTC
GCGAATGGGCAATCCAACCC

Product: acyl-CoA dehydrogenase-like protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MDLGVSDRVKPLVEAVRRMVRDDIAPLDMEYHAEVGQHPSGDRFAMTDRQIEILKTLKDKAKGQGLWNFWLTDSQDGYGL
STVEYAYLAEEMGAVSIAPEIFNCNAPDTGNMEVLERYGSEAQRTRWLPDLMAGVSRSAYLMTEPSVASSDATQISLKCE
RQGEDYVLNGEKYWATGAGDPRCALYIVMVCTDPGAAKHARHSMLLIPSDAAGIETLRPMQVFGQDDAPHGHMHIRFTDV
RVPIDAMVLGEGRGFEVAQGRLGPGRIHHCMRAIGRAEYALELMVKRGLTREAFGKPLVELGANYDIIANARIDIEMTRL
LCLKAAWMMDHAGVRAAQPWISKVKVQAPLMALQVVDEAMQMHGATGLSQDTPLSRIWADLRTLRLADGPDAVHRRQVAR
AELRKHTNTSQ

Sequences:

>Translated_411_residues
MDLGVSDRVKPLVEAVRRMVRDDIAPLDMEYHAEVGQHPSGDRFAMTDRQIEILKTLKDKAKGQGLWNFWLTDSQDGYGL
STVEYAYLAEEMGAVSIAPEIFNCNAPDTGNMEVLERYGSEAQRTRWLPDLMAGVSRSAYLMTEPSVASSDATQISLKCE
RQGEDYVLNGEKYWATGAGDPRCALYIVMVCTDPGAAKHARHSMLLIPSDAAGIETLRPMQVFGQDDAPHGHMHIRFTDV
RVPIDAMVLGEGRGFEVAQGRLGPGRIHHCMRAIGRAEYALELMVKRGLTREAFGKPLVELGANYDIIANARIDIEMTRL
LCLKAAWMMDHAGVRAAQPWISKVKVQAPLMALQVVDEAMQMHGATGLSQDTPLSRIWADLRTLRLADGPDAVHRRQVAR
AELRKHTNTSQ
>Mature_411_residues
MDLGVSDRVKPLVEAVRRMVRDDIAPLDMEYHAEVGQHPSGDRFAMTDRQIEILKTLKDKAKGQGLWNFWLTDSQDGYGL
STVEYAYLAEEMGAVSIAPEIFNCNAPDTGNMEVLERYGSEAQRTRWLPDLMAGVSRSAYLMTEPSVASSDATQISLKCE
RQGEDYVLNGEKYWATGAGDPRCALYIVMVCTDPGAAKHARHSMLLIPSDAAGIETLRPMQVFGQDDAPHGHMHIRFTDV
RVPIDAMVLGEGRGFEVAQGRLGPGRIHHCMRAIGRAEYALELMVKRGLTREAFGKPLVELGANYDIIANARIDIEMTRL
LCLKAAWMMDHAGVRAAQPWISKVKVQAPLMALQVVDEAMQMHGATGLSQDTPLSRIWADLRTLRLADGPDAVHRRQVAR
AELRKHTNTSQ

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI211971008, Length=357, Percent_Identity=54.3417366946779, Blast_Score=381, Evalue=1e-106,
Organism=Homo sapiens, GI48976061, Length=357, Percent_Identity=54.3417366946779, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI38505218, Length=354, Percent_Identity=49.7175141242938, Blast_Score=348, Evalue=5e-96,
Organism=Homo sapiens, GI187960098, Length=406, Percent_Identity=27.0935960591133, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI4557231, Length=406, Percent_Identity=27.0935960591133, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI21361497, Length=398, Percent_Identity=25.6281407035176, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI4501859, Length=393, Percent_Identity=23.9185750636132, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI4557233, Length=352, Percent_Identity=27.5568181818182, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI7656849, Length=350, Percent_Identity=25.4285714285714, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI4501857, Length=412, Percent_Identity=23.5436893203883, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI226958412, Length=400, Percent_Identity=24.5, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI226958414, Length=326, Percent_Identity=25.4601226993865, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI76496475, Length=405, Percent_Identity=25.4320987654321, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI4557235, Length=405, Percent_Identity=25.4320987654321, Blast_Score=92, Evalue=7e-19,
Organism=Escherichia coli, GI87081958, Length=322, Percent_Identity=27.0186335403727, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786223, Length=297, Percent_Identity=23.2323232323232, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562446, Length=407, Percent_Identity=44.4717444717445, Blast_Score=350, Evalue=7e-97,
Organism=Caenorhabditis elegans, GI17533517, Length=408, Percent_Identity=26.7156862745098, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17534899, Length=364, Percent_Identity=26.0989010989011, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17570075, Length=407, Percent_Identity=25.7985257985258, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17569725, Length=408, Percent_Identity=25.2450980392157, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71985184, Length=357, Percent_Identity=26.3305322128852, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17505929, Length=354, Percent_Identity=24.2937853107345, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17506239, Length=288, Percent_Identity=26.7361111111111, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=401, Percent_Identity=23.1920199501247, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=322, Percent_Identity=25.1552795031056, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=408, Percent_Identity=22.5490196078431, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=260, Percent_Identity=25.7692307692308, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71990804, Length=288, Percent_Identity=24.3055555555556, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17534353, Length=289, Percent_Identity=25.6055363321799, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI32563615, Length=191, Percent_Identity=27.7486910994764, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24660351, Length=399, Percent_Identity=26.3157894736842, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21356377, Length=336, Percent_Identity=27.3809523809524, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24646207, Length=345, Percent_Identity=27.2463768115942, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI281363737, Length=327, Percent_Identity=26.2996941896024, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24666513, Length=396, Percent_Identity=21.4646464646465, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI19920834, Length=325, Percent_Identity=26.1538461538462, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355753, Length=288, Percent_Identity=23.2638888888889, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 45579; Mature: 45579

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGVSDRVKPLVEAVRRMVRDDIAPLDMEYHAEVGQHPSGDRFAMTDRQIEILKTLKDK
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHH
AKGQGLWNFWLTDSQDGYGLSTVEYAYLAEEMGAVSIAPEIFNCNAPDTGNMEVLERYGS
HCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEECCHHEECCCCCCCCHHHHHHHCC
EAQRTRWLPDLMAGVSRSAYLMTEPSVASSDATQISLKCERQGEDYVLNGEKYWATGAGD
HHHHHHCCHHHHHCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCEEECCCEEEECCCCC
PRCALYIVMVCTDPGAAKHARHSMLLIPSDAAGIETLRPMQVFGQDDAPHGHMHIRFTDV
CCEEEEEEEEECCCCCHHHCCCCEEEEECCCCCCHHCCHHHHHCCCCCCCCEEEEEEEEE
RVPIDAMVLGEGRGFEVAQGRLGPGRIHHCMRAIGRAEYALELMVKRGLTREAFGKPLVE
ECCEEEEEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHH
LGANYDIIANARIDIEMTRLLCLKAAWMMDHAGVRAAQPWISKVKVQAPLMALQVVDEAM
HCCCCEEEECCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QMHGATGLSQDTPLSRIWADLRTLRLADGPDAVHRRQVARAELRKHTNTSQ
HHHCCCCCCCCCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDLGVSDRVKPLVEAVRRMVRDDIAPLDMEYHAEVGQHPSGDRFAMTDRQIEILKTLKDK
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHH
AKGQGLWNFWLTDSQDGYGLSTVEYAYLAEEMGAVSIAPEIFNCNAPDTGNMEVLERYGS
HCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEECCHHEECCCCCCCCHHHHHHHCC
EAQRTRWLPDLMAGVSRSAYLMTEPSVASSDATQISLKCERQGEDYVLNGEKYWATGAGD
HHHHHHCCHHHHHCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCEEECCCEEEECCCCC
PRCALYIVMVCTDPGAAKHARHSMLLIPSDAAGIETLRPMQVFGQDDAPHGHMHIRFTDV
CCEEEEEEEEECCCCCHHHCCCCEEEEECCCCCCHHCCHHHHHCCCCCCCCEEEEEEEEE
RVPIDAMVLGEGRGFEVAQGRLGPGRIHHCMRAIGRAEYALELMVKRGLTREAFGKPLVE
ECCEEEEEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHH
LGANYDIIANARIDIEMTRLLCLKAAWMMDHAGVRAAQPWISKVKVQAPLMALQVVDEAM
HCCCCEEEECCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QMHGATGLSQDTPLSRIWADLRTLRLADGPDAVHRRQVARAELRKHTNTSQ
HHHCCCCCCCCCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]